Nerve Compression Syndromes

神经压迫综合征
  • 文章类型: Journal Article
    背景:上/中肘部神经卡压(CN-E)是下腰痛(LBP)的诱发因素。疼痛检测问卷用于表征CN-E症状。
    方法:由CN-E引起的LBP的19例连续患者(上CN-E=7;中CN-E=12)参加了手术前的日语疼痛DETECT问卷调查。12分或更低的分数被记录为“不太可能的神经病变成分”,19分或更高的“神经性疼痛可能”,得分在13到18之间,即“神经性疼痛可能”。LBP严重程度记录在数字评定量表上,罗兰-莫里斯残疾问卷,和EuroQol-5维度-5级别。
    结果:平均疼痛检测评分为11.8分,在较高的CN-E组和中间的CN-E组之间没有显著差异。我们在13例患者中将下腰痛分类为不太可能有神经性成分,2名患者可能有神经病变成分,4名患者可能患有神经病。painDETECT评分≤12分和≥13分的患者疼痛水平无显著差异。所有患者均报告触发疼痛;电击疼痛阳性率高,放射疼痛,疼痛发作和低度的灼热或刺痛感,轻微的触摸引起的疼痛,和冷或热刺激引起的疼痛。
    结论:痛苦检测问卷可能无法可靠地将由上/中CN-E引起的LBP确定为神经性疼痛。必须仔细诊断由于CN-E引起的LBP,因为症状类似于伤害性疼痛。
    BACKGROUND: Superior/middle cluneal nerve entrapment (CN-E) is an elicitor of low back pain (LBP). The painDETECT questionnaire is used to characterize CN-E symptoms.
    METHODS: Nineteen consecutive patients with LBP caused by CN-E (superior CN-E = 7; middle CN-E = 12) participated in a Japanese language painDETECT questionnaire survey before surgery. A score of 12 or lower was recorded as \'neuropathic component unlikely\', a score of 19 or higher as \'neuropathic pain likely\', and scores between 13 and 18 as \'neuropathic pain possible\'. LBP severity was recorded on a numerical rating scale, the Roland-Morris Disability Questionnaire, and the EuroQol-5 dimension-5 level.
    RESULTS: The mean painDETECT score was 11.8 and did not significantly differ between the superior CN-E and middle CN-E groups. We classified low back pain as unlikely to have a neuropathic component in 13 patients, as likely to have a neuropathic component in 2 patients, and as possibly neuropathic in 4 patients. There was no significant difference in the pain level of patients with scores of ≤12 and ≥13 on painDETECT. All patients reported trigger pain; the positive rate was high for electric shock pain, radiating pain, and pain attacks and low for a burning or tingling sensation, pain elicited by a light touch, and pain caused by cold or hot stimulation.
    CONCLUSIONS: The painDETECT questionnaire may not reliably identify LBP caused by superior/middle CN-E as neuropathic pain. A diagnosis of LBP due to CN-E must be made carefully because symptoms resemble nociceptive pain.
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  • 文章类型: Journal Article
    超声和磁共振神经成像是帮助评估压迫性神经病的有用方式。尽管它们在神经微结构的分辨率和监测术后神经恢复的能力方面仍然有限。光学相干层析成像,临床前成像模式,很有希望能够更好地识别周围神经的结构和潜在的生理变化,但在广泛的临床实施之前需要额外的测试和研究。神经成像的进一步进展可以阐明术中神经损伤区的可视化能力,监测神经再生的进展,并在神经恢复期间定位问题。
    Ultrasound and magnetic resonance neurography are useful modalities to aid in the assessment of compressive neuropathies, although they are still limited in their resolution of nerve microstructure and their capacity to monitor postoperative nerve recovery. Optical coherence tomography, a preclinical imaging modality, is promising in its ability to better identify structural and potential physiologic changes to peripheral nerves, but requires additional testing and research prior to widespread clinical implementation. Further advances in nerve imaging may elucidate the ability to visualize the zone of nerve injury intraoperatively, monitor the progression of nerve regeneration, and localize problems during nerve recovery.
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  • 文章类型: Journal Article
    先进的解剖学知识是周围神经外科医生的先决条件。本文用于提供可能发生神经卡压或压迫的解剖区域的轮廓。每个部分都细分为病因的解剖区域,适应症,并讨论了相关和异常的解剖学,以及有问题的解剖部位的常见手术方法。目的是为周围神经外科医生提供概述,并提供宝贵的资源,为该患者人群提供更好的理解和最佳护理。
    Advance knowledge of anatomy is a prerequisite for the peripheral nerve surgeon. This article serves to provide an outline of anatomic regions where nerve entrapment or compression can occur. Each section is subdivided into anatomic regions where the etiology, indications, and relevant and aberrant anatomy are discussed, as well as common surgical approaches to the problematic anatomic site. The purpose is to provide an overview for the peripheral nerve surgeon and offer a valuable resource to provide a better understanding and optimal care for this patient population.
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  • 文章类型: Journal Article
    目的复杂区域疼痛综合征(CRPS)需要进一步了解。因此,本研究旨在分析术前和术中因素是否与术后CRPS的发生有关.方法我们回顾了2015年至2021年接受前臂和手部手术的1,183例患者的病历。感兴趣的数据,也就是说,诊断,切口,合成材料,和麻醉,被收集,列表,并进行了统计分析,随后计算赔率比。结果大部分患者为女性,年龄在30至59岁之间,并选择性寻求服务(67%的案件)。诊断包括软组织创伤(43%),骨创伤(31.6%),和压缩综合症(25.5%)。在此期间,45名(3.8%)受试者发生CRPS。统计分析表明,压迫综合征患者发生CRPS的几率是其两倍,尤其是腕管综合征(CTS),这代表了我们服务中进行的大多数手术(24%)。7.6%的病例出现两个或两个以上切口,这增加了发生术后CRPS的机会。性别,年龄,使用PF合成材料,麻醉类型在统计学上没有增加发生术后CRPS的风险.结论总之,CRPS的发病率较低;然而,了解和认识术后预防和积极筛查的危险因素至关重要。
    Objective  Complex regional pain syndrome (CRPS) requires further understanding. Thus, the present study aimed to analyze if pre- and intraoperative factors may be related to the development of CRPS in the postoperative period. Methods  We reviewed 1,183 medical records of patients undergoing forearm and hand surgeries from 2015 to 2021. The data of interest, that is, diagnosis, incisions, synthesis material, and anesthesia, were collected, tabulated, and statistically analyzed, with subsequent calculation of the odds ratios. Results  Most patients were female, aged between 30 and 59 years, and sought the service electively (67% of the cases). The diagnoses included soft tissue trauma (43%), bone trauma (31.6%), and compressive syndromes (25.5%). During this period, 45 (3.8%) subjects developed CRPS. The statistical analysis showed that the chance of developing CRPS is twice as high in patients with compressive syndrome, especially carpal tunnel syndrome (CTS), which represented most surgeries performed in our service (24%). Two or more incisions occurred in 7.6% of the cases, which tripled the chance of developing postoperative CRPS. Gender, age, use pf synthetic material, type of anesthesia type did not statistically increase the risk of developing postoperative CRPS. Conclusion  In short, the incidence of CRPS is low; however, it is critical to know and recognize the risk factors for prevention and active screening in the postoperative period.
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  • 文章类型: Case Reports
    背景技术咽部肿块对迷走神经的压迫是一种有据可查的病症,其可导致窦房结功能障碍(SND)。然而,关于扁桃体脓肿引起的外在迷走神经压迫的文献很少。病例报告一名59岁的女性,有哮喘和慢性咽喉不适病史,因心动过缓被送往急诊科,心悸,和声音的变化。贝类过敏住院后,耳鼻喉科检查显示右扁桃体增大,推荐扁桃体切除术,但是日程安排挑战仍然存在。病人报告有轻微的咽喉疼痛,吞咽困难,声音嘶哑,鼻漏,和劳力性呼吸困难,并被纳入评估扁桃体周围肿块。她被发现心动过缓,心率为47,心电图显示SND。沙丁胺醇和异丙托铵雾化器,以及地塞米松和泮托拉唑,已启动。有了这种治疗,患者症状改善,新心率为68。她在门诊出院,但不幸的是失去了后续行动。结论该病例显示扁桃体脓肿导致的外在迷走神经压迫引起的窦房结功能障碍。迷走神经的压力会引发心动过缓和低血压,可能是由于局部质量效应引起的传入迷走神经信号的代偿性过度放电。早期识别和抗生素治疗对于预防心脏并发症至关重要。临床医生必须对这些外在原因保持警惕,特别是有慢性咽喉痛和心脏症状的患者。需要进一步的研究和病例报告来加深我们对这种罕见但重要的关联的理解。
    BACKGROUND Compression of the vagus nerve by a pharyngeal mass is a well-documented condition that can result in sinus node dysfunction (SND). However, there is scarce literature on extrinsic vagal nerve compression from a tonsillar abscess. CASE REPORT A 59-year-old woman with a history of asthma and chronic throat discomfort presented to the Emergency Department with bradycardia, palpitations, and voice changes. Following a shellfish allergy hospitalization, an otolaryngology evaluation revealed an enlarged right tonsil, recommending tonsillectomy, but scheduling challenges persisted. The patient reported mild throat pain, dysphagia, hoarseness, rhinorrhea, and exertional dyspnea and was admitted for the evaluation of peritonsillar mass. She was found to be bradycardic with a heart rate of 47, with an electrocardiogram revealing SND. Albuterol and ipratropium nebulizers, as well as dexamethasone and pantoprazole, were initiated. With this treatment, the patient symptomatically improved with a new heart rate of 68. She was discharged with outpatient appointments, but was unfortunately lost to follow-up. CONCLUSIONS This case reveals sinus node dysfunction resulting from extrinsic vagal nerve compression by a tonsillar abscess. Pressure on the vagus nerve can trigger bradycardia and low blood pressure, possibly due to compensatory overfiring of afferent vagal nerve signals from local mass effect. Early recognition and antibiotic treatment are essential to prevent cardiac complications. Clinicians must remain vigilant for such extrinsic causes, particularly in patients with chronic sore throat and cardiac symptoms. Further research and case reports are needed to deepen our understanding of this rare yet significant association.
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  • 文章类型: Case Reports
    方法:本病例报告描述了一名患者,该患者在radium神经的浅表感觉分支的分布中出现感觉异常,并接受了手术治疗。术中,有一个独特的内部压缩的原因是一个罕见的浅桡动脉变异运行在它附近。神经从动脉动员,筋膜释放。患者术后症状缓解。
    结论:据我们所知,这种压迫的原因以前没有描述过,在鉴别诊断中应考虑。此外,在静脉穿刺和手术入路期间,临床医生应该意识到这种解剖变异。
    METHODS: This case report describes a patient with paresthesia in the distribution of the superficial sensory branch of the radial nerve that was treated with surgery. Intraoperatively, there was a unique cause of internal compression by a rare superficial radial artery variant running adjacent to it. The nerve was mobilized from the artery with fascial releases. The patient had symptom resolution postoperatively.
    CONCLUSIONS: To our knowledge, this cause of compression has not been described before and should be considered in a differential diagnosis. In addition, clinicians should be aware of this anatomical variant during venipunctures and surgical approaches.
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  • 文章类型: Case Reports
    本文报道一例女性患者入院,右前臂肿胀和皮下肿块,最初怀疑是多发性神经纤维瘤。然而,通过术前成像和手术,最终诊断为浅表血栓性静脉炎。这种情况导致radial神经分支陷入,导致明显的神经卡压和放射疼痛。手术包括切除炎症组织和血栓,头静脉结扎,并完全释放桡神经分支.术后病理证实为表浅血栓性静脉炎。通过这个案子,我们强调综合利用临床的重要性,成像,和手术干预,以获得更准确的诊断和治疗。这是由于浅表血栓性静脉炎引起的radial神经分支卡压的首次临床报告。
    This article reports a case of a female patient admitted with swelling and subcutaneous mass in the right forearm, initially suspected to be multiple nerve fibroma. However, through preoperative imaging and surgery, the final diagnosis confirmed superficial thrombophlebitis. This condition resulted in entrapment of the radial nerve branch, leading to noticeable nerve entrapment and radiating pain. The surgery involved the excision of inflammatory tissue and thrombus, ligation of the cephalic vein, and complete release of the radial nerve branch. Postoperative pathology confirmed the presence of Superficial Thrombophlebitis. Through this case, we emphasize the importance of comprehensive utilization of clinical, imaging, and surgical interventions for more accurate diagnosis and treatment. This is the first clinical report of radial nerve branch entrapment due to superficial thrombophlebitis.
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  • 文章类型: Journal Article
    前瞻性招募30例男性原发性腹股沟疝患者行原发性腹股沟疝修补术,进行髂腹股沟神经切除和评估。切除的髂腹股沟神经的三个样本(近端,运河,和远端)使用Masson三色染色法进行评估,以测量束和总神经横截面积并检测胶原蛋白的变化。
    与观察到的大效应大小的近端对照相比,管段中的束横截面积显着降低(p=0.016,η2=0.16)。位置之间的神经横截面积没有显着差异,但是在位置之间观察到中等到较大的效应大小(p=0.165,η2=0.105)。位置之间的胶原蛋白含量和效应大小均无显着差异(p=0.99,η2=1.503×10-4)。解释。腹股沟管束横截面积的减小进一步表明,疝组织施加的慢性压力与轴突变性一致。胶原蛋白含量沿着神经的长度均匀分布。需要对更大样本进行进一步研究,以证实观察到的神经位置对总神经横截面积和轴突损失的影响。
    UNASSIGNED: 30 male patients with primary inguinal hernias undergoing primary inguinal herniorrhaphy were prospectively recruited for ilioinguinal nerve resection and evaluation. Three samples of the resected ilioinguinal nerve (proximal, canal, and distal) were evaluated using Masson\'s trichrome stain to measure fascicle and total nerve cross-sectional area and detect changes in collagen.
    UNASSIGNED: The fascicle cross-sectional area in the canal segment was significantly decreased compared to the proximal control with a large effect size observed (p = 0.016, η2  = 0.16). There was no significant difference in the nerve cross-sectional area between locations, but there was a moderate to large effect size observed between locations (p = 0.165, η2  = 0.105). There was no significant difference in collagen content nor effect size observed between locations (p = 0.99, η2  = 1.503 × 10-4). Interpretation. The decrease in the fascicle cross-sectional area within the inguinal canal further suggests that there is chronic pressure applied by hernia tissue consistent with axon degeneration. Collagen content is uniformly distributed along the length of the nerve. Further studies with larger samples are needed to confirm the observed effect of nerve location on the total nerve cross-sectional area and axon loss.
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  • 文章类型: Case Reports
    方法:一名65岁的女性患者,表现为右手腕弥漫性疼痛和肿胀,右手感觉异常,大鱼间消瘦。她的磁共振成像扫描提示腕部屈肌腱鞘炎,正中神经受多个水稻体压迫。她接受了切除活检和正中神经减压术。通过聚合酶链反应(GeneXpert)检测结核分枝杆菌,组织病理学发现干酪样肉芽肿。患者术后开始接受抗结核化疗。
    结论:在印度等地方病国家,结核性屈肌腱鞘炎必须始终是腕关节肿胀的鉴别诊断。
    METHODS: A 65-year-old female patient presented with complaints of diffuse pain and swelling in her right wrist with paresthesia in her right hand with thenar wasting. Her magnetic resonance imaging scan was suggestive of flexor tenosynovitis of the wrist with compression of the median nerve with multiple rice bodies. She underwent excisional biopsy along with median nerve decompression. Mycobacterium tuberculosis was detected by polymerase chain reaction (GeneXpert), and histopathology identified caseous granulomas. The patient was started on antitubercular chemotherapy postoperatively.
    CONCLUSIONS: In endemic countries such as India, tuberculous flexor tenosynovitis must always be a differential diagnosis in cases of wrist swelling with rice bodies.
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  • 文章类型: Case Reports
    前皮神经卡压综合征(ACNES)的特征是腹壁神经痛。我们报告了一名85岁的女性,在双极髋关节置换术中由固定装置引起的ACNES。预防ACNES作为围手术期周围神经损伤,在手术过程中保持病人在适当的位置是很重要的。阳性Carnett标志意味着腹痛起源于腹壁,可用于诊断ACNES。因此,医师应检查Carnett的体征,以区分术后发生腹痛的患者的ACNES。
    Anterior cutaneous nerve entrapment syndrome (ACNES) is characterized by abdominal wall neuralgia. We report an 85-year-old woman with ACNES caused by a fixation device during the bipolar hip arthroplasty. To prevent ACNES as a perioperative peripheral nerve injury, it is important to maintain patients in the appropriate position during the operation. A positive Carnett\'s sign means the abdominal pain originates from the abdominal wall and is useful in diagnosing ACNES. Thus, physicians should examine Carnett\'s sign to differentiate ACNES in patients with abdominal pain developing after an operation.
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