Nerve Compression Syndromes

神经压迫综合征
  • 文章类型: Journal Article
    目的复杂区域疼痛综合征(CRPS)需要进一步了解。因此,本研究旨在分析术前和术中因素是否与术后CRPS的发生有关.方法我们回顾了2015年至2021年接受前臂和手部手术的1,183例患者的病历。感兴趣的数据,也就是说,诊断,切口,合成材料,和麻醉,被收集,列表,并进行了统计分析,随后计算赔率比。结果大部分患者为女性,年龄在30至59岁之间,并选择性寻求服务(67%的案件)。诊断包括软组织创伤(43%),骨创伤(31.6%),和压缩综合症(25.5%)。在此期间,45名(3.8%)受试者发生CRPS。统计分析表明,压迫综合征患者发生CRPS的几率是其两倍,尤其是腕管综合征(CTS),这代表了我们服务中进行的大多数手术(24%)。7.6%的病例出现两个或两个以上切口,这增加了发生术后CRPS的机会。性别,年龄,使用PF合成材料,麻醉类型在统计学上没有增加发生术后CRPS的风险.结论总之,CRPS的发病率较低;然而,了解和认识术后预防和积极筛查的危险因素至关重要。
    Objective  Complex regional pain syndrome (CRPS) requires further understanding. Thus, the present study aimed to analyze if pre- and intraoperative factors may be related to the development of CRPS in the postoperative period. Methods  We reviewed 1,183 medical records of patients undergoing forearm and hand surgeries from 2015 to 2021. The data of interest, that is, diagnosis, incisions, synthesis material, and anesthesia, were collected, tabulated, and statistically analyzed, with subsequent calculation of the odds ratios. Results  Most patients were female, aged between 30 and 59 years, and sought the service electively (67% of the cases). The diagnoses included soft tissue trauma (43%), bone trauma (31.6%), and compressive syndromes (25.5%). During this period, 45 (3.8%) subjects developed CRPS. The statistical analysis showed that the chance of developing CRPS is twice as high in patients with compressive syndrome, especially carpal tunnel syndrome (CTS), which represented most surgeries performed in our service (24%). Two or more incisions occurred in 7.6% of the cases, which tripled the chance of developing postoperative CRPS. Gender, age, use pf synthetic material, type of anesthesia type did not statistically increase the risk of developing postoperative CRPS. Conclusion  In short, the incidence of CRPS is low; however, it is critical to know and recognize the risk factors for prevention and active screening in the postoperative period.
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  • 文章类型: Case Reports
    背景技术咽部肿块对迷走神经的压迫是一种有据可查的病症,其可导致窦房结功能障碍(SND)。然而,关于扁桃体脓肿引起的外在迷走神经压迫的文献很少。病例报告一名59岁的女性,有哮喘和慢性咽喉不适病史,因心动过缓被送往急诊科,心悸,和声音的变化。贝类过敏住院后,耳鼻喉科检查显示右扁桃体增大,推荐扁桃体切除术,但是日程安排挑战仍然存在。病人报告有轻微的咽喉疼痛,吞咽困难,声音嘶哑,鼻漏,和劳力性呼吸困难,并被纳入评估扁桃体周围肿块。她被发现心动过缓,心率为47,心电图显示SND。沙丁胺醇和异丙托铵雾化器,以及地塞米松和泮托拉唑,已启动。有了这种治疗,患者症状改善,新心率为68。她在门诊出院,但不幸的是失去了后续行动。结论该病例显示扁桃体脓肿导致的外在迷走神经压迫引起的窦房结功能障碍。迷走神经的压力会引发心动过缓和低血压,可能是由于局部质量效应引起的传入迷走神经信号的代偿性过度放电。早期识别和抗生素治疗对于预防心脏并发症至关重要。临床医生必须对这些外在原因保持警惕,特别是有慢性咽喉痛和心脏症状的患者。需要进一步的研究和病例报告来加深我们对这种罕见但重要的关联的理解。
    BACKGROUND Compression of the vagus nerve by a pharyngeal mass is a well-documented condition that can result in sinus node dysfunction (SND). However, there is scarce literature on extrinsic vagal nerve compression from a tonsillar abscess. CASE REPORT A 59-year-old woman with a history of asthma and chronic throat discomfort presented to the Emergency Department with bradycardia, palpitations, and voice changes. Following a shellfish allergy hospitalization, an otolaryngology evaluation revealed an enlarged right tonsil, recommending tonsillectomy, but scheduling challenges persisted. The patient reported mild throat pain, dysphagia, hoarseness, rhinorrhea, and exertional dyspnea and was admitted for the evaluation of peritonsillar mass. She was found to be bradycardic with a heart rate of 47, with an electrocardiogram revealing SND. Albuterol and ipratropium nebulizers, as well as dexamethasone and pantoprazole, were initiated. With this treatment, the patient symptomatically improved with a new heart rate of 68. She was discharged with outpatient appointments, but was unfortunately lost to follow-up. CONCLUSIONS This case reveals sinus node dysfunction resulting from extrinsic vagal nerve compression by a tonsillar abscess. Pressure on the vagus nerve can trigger bradycardia and low blood pressure, possibly due to compensatory overfiring of afferent vagal nerve signals from local mass effect. Early recognition and antibiotic treatment are essential to prevent cardiac complications. Clinicians must remain vigilant for such extrinsic causes, particularly in patients with chronic sore throat and cardiac symptoms. Further research and case reports are needed to deepen our understanding of this rare yet significant association.
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  • 文章类型: Case Reports
    本文报道一例女性患者入院,右前臂肿胀和皮下肿块,最初怀疑是多发性神经纤维瘤。然而,通过术前成像和手术,最终诊断为浅表血栓性静脉炎。这种情况导致radial神经分支陷入,导致明显的神经卡压和放射疼痛。手术包括切除炎症组织和血栓,头静脉结扎,并完全释放桡神经分支.术后病理证实为表浅血栓性静脉炎。通过这个案子,我们强调综合利用临床的重要性,成像,和手术干预,以获得更准确的诊断和治疗。这是由于浅表血栓性静脉炎引起的radial神经分支卡压的首次临床报告。
    This article reports a case of a female patient admitted with swelling and subcutaneous mass in the right forearm, initially suspected to be multiple nerve fibroma. However, through preoperative imaging and surgery, the final diagnosis confirmed superficial thrombophlebitis. This condition resulted in entrapment of the radial nerve branch, leading to noticeable nerve entrapment and radiating pain. The surgery involved the excision of inflammatory tissue and thrombus, ligation of the cephalic vein, and complete release of the radial nerve branch. Postoperative pathology confirmed the presence of Superficial Thrombophlebitis. Through this case, we emphasize the importance of comprehensive utilization of clinical, imaging, and surgical interventions for more accurate diagnosis and treatment. This is the first clinical report of radial nerve branch entrapment due to superficial thrombophlebitis.
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  • 文章类型: Journal Article
    前瞻性招募30例男性原发性腹股沟疝患者行原发性腹股沟疝修补术,进行髂腹股沟神经切除和评估。切除的髂腹股沟神经的三个样本(近端,运河,和远端)使用Masson三色染色法进行评估,以测量束和总神经横截面积并检测胶原蛋白的变化。
    与观察到的大效应大小的近端对照相比,管段中的束横截面积显着降低(p=0.016,η2=0.16)。位置之间的神经横截面积没有显着差异,但是在位置之间观察到中等到较大的效应大小(p=0.165,η2=0.105)。位置之间的胶原蛋白含量和效应大小均无显着差异(p=0.99,η2=1.503×10-4)。解释。腹股沟管束横截面积的减小进一步表明,疝组织施加的慢性压力与轴突变性一致。胶原蛋白含量沿着神经的长度均匀分布。需要对更大样本进行进一步研究,以证实观察到的神经位置对总神经横截面积和轴突损失的影响。
    UNASSIGNED: 30 male patients with primary inguinal hernias undergoing primary inguinal herniorrhaphy were prospectively recruited for ilioinguinal nerve resection and evaluation. Three samples of the resected ilioinguinal nerve (proximal, canal, and distal) were evaluated using Masson\'s trichrome stain to measure fascicle and total nerve cross-sectional area and detect changes in collagen.
    UNASSIGNED: The fascicle cross-sectional area in the canal segment was significantly decreased compared to the proximal control with a large effect size observed (p = 0.016, η2  = 0.16). There was no significant difference in the nerve cross-sectional area between locations, but there was a moderate to large effect size observed between locations (p = 0.165, η2  = 0.105). There was no significant difference in collagen content nor effect size observed between locations (p = 0.99, η2  = 1.503 × 10-4). Interpretation. The decrease in the fascicle cross-sectional area within the inguinal canal further suggests that there is chronic pressure applied by hernia tissue consistent with axon degeneration. Collagen content is uniformly distributed along the length of the nerve. Further studies with larger samples are needed to confirm the observed effect of nerve location on the total nerve cross-sectional area and axon loss.
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  • 文章类型: Case Reports
    强调在大腿后区表现出症状的患者中评估股后皮神经(PFCN)压迫的重要性。一名42岁的男性牙医,最初诊断为半腱肌撕裂,大腿后部持续疼痛和刺痛,在我们的门诊寻求治疗。尽管物理治疗不成功,综合评估显示,PFCN在骶结节韧带和半腱肌残端之间异常截留。患者接受了一系列专门的治疗干预,包括软组织松解术,运动学录音,和生活方式的改变。病人的症状,包括疼痛和刺痛,完全解决了,使他可以长时间坐在凳子上而不会感到不适。此病例报告强调物理治疗师需要考虑在大腿后部疼痛和刺痛的患者中发生PFCN截留的可能性。这些症状很容易被误认为是坐骨神经痛或腿筋肌肉撕裂等疾病。
    To underscore the importance of evaluating the entrapment of the posterior femoral cutaneous nerve (PFCN) in patients exhibiting symptoms in the posterior thigh region. A 42-year-old male dentist, initially diagnosed with a semitendinosus muscle tear and persistent pain and tingling in the posterior thigh, sought treatment at our outpatient clinic. Despite unsuccessful physiotherapy, a comprehensive evaluation revealed an unusual entrapment of the PFCN between the sacrotuberous ligament and the semitendinosus muscle stump. The patient was subjected to a series of specialized therapeutic interventions, including soft tissue release, kinesiology taping, and lifestyle modifications. The patient\'s symptoms, including pain and tingling, were completely resolved, enabling him to sit on a stool for extended periods without discomfort. This case presentation emphasizes the need for physical therapists to consider the possibility of PFCN entrapment in patients experiencing pain and tingling in the posterior thigh. These symptoms can be easily mistaken for conditions such as sciatica or a hamstring muscle tear.
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  • 文章类型: Journal Article
    背景:意外的硬脑膜撕裂(DT)是腰椎手术中最常见的术中并发症。单侧双门内窥镜技术(UBE)在治疗各种腰椎退行性疾病中日益普及;然而,UBE特有的DT发生率和危险因素仍未确定.因此,本研究旨在评估DTs在UBE中的发生率和危险因素。
    方法:使用2018年11月至2021年12月在我们机构接受UBE治疗退行性腰椎疾病的所有患者的数据来评估人口统计学的影响,诊断,以及意外DT风险的手术类型。
    结果:总体而言,24/608名患者(3.95%)经历了DTs,并接受了初次缝合修复或卧床休息治疗。尽管有几名患者出现了脑脊液(CSF)泄漏的轻度症状,没有严重的术后后遗症,如神经根卡压,脑膜炎,或颅内出血。此外,DT和性别之间没有发现显著的相关性(P=0.882),体重指数(BMI)(P=0.758),吸烟状况(P=0.506),糖尿病(P=0.672),高血压(P=0.187),或外科医生经验(P=0.442)。然而,老年患者比年轻患者更容易经历DT(P=0.034),与腰椎间盘突出症(LDH)患者相比,腰椎管狭窄(LSS)患者更容易发生DT(P=0.035)。此外,DT在翻修术和初次手术中更为常见(P<0.0001),在双侧减压的单侧椎板切开术(ULBD)和单侧减压术中更为常见(P=0.031)。单因素Logistic回归分析显示,年龄,LSS,ULBD,和翻修手术是DT的重要危险因素。
    结论:在此UBE队列中,我们发现DT的发病率为3.95%。此外,年龄较大,LSS,ULBD,修正手术显著增加了UBE手术中DT的风险。
    BACKGROUND: An unintended dural tear (DT) is the most common intraoperative complication of lumbar spine surgery. The unilateral biportal endoscopic technique (UBE) has become increasingly popular for treating various degenerative diseases of the lumbar spine; however, the DT incidence and risk factors specific to UBE remain undetermined. Therefore, this study aimed to evaluate the incidence and risk factors of DTs in UBE.
    METHODS: Data from all patients who underwent UBE for degenerative lumbar spinal diseases from November 2018 to December 2021 at our institution were used to assess the effects of demographics, diagnosis, and type of surgery on unintended DT risk.
    RESULTS: Overall, 24/608 patients (3.95%) experienced DTs and were treated with primary suture repair or bed rest. Although several patients experienced mild symptoms of cerebrospinal fluid (CSF) leaks, no serious postoperative sequelae such as nerve root entrapment, meningitis, or intracranial hemorrhage occurred. Additionally, no significant correlations were identified between DT and sex (P = 0.882), body mass index (BMI) (P = 0.758), smoking status (P = 0.506), diabetes (P = 0.672), hypertension (P = 0.187), or surgeon experience (P = 0.442). However, older patients were more likely to experience DT than younger patients (P = 0.034), and patients with lumbar spinal stenosis (LSS) were more likely to experience DT than patients with lumbar disc herniation (LDH) (P = 0.035). Additionally, DT was more common in revision versus primary surgery (P < 0.0001) and in unilateral laminotomy with bilateral decompression (ULBD) versus unilateral decompression (P = 0.031). Univariate logistic regression analysis revealed that age, LSS, ULBD, and revision surgery were significant risk factors for DT.
    CONCLUSIONS: In this UBE cohort, we found that the incidence of DT was 3.95%. Additionally, older age, LSS, ULBD, and revision surgery significantly increased the risk of DT in UBE surgery.
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  • 文章类型: Journal Article
    没有治疗儿童前皮神经卡压综合征(ACNES)的循证指南。本综述的主要目的是审查支持当前使用的治疗干预措施的证据。根据世界卫生组织(WHO)儿童慢性疼痛管理指南,这些患者及其家属和护理人员应在生物心理社会模式的背景下进行治疗;疼痛不应纯粹作为生物医学问题进行治疗.因此,我们的第二个目的是评估这些干预措施是否在生物心理社会模型的背景下应用,利用跨学科或多学科方法。
    对文献进行范围审查,以探索儿童ACNES的治疗策略。为了确保对有关该主题的已发表文献进行全面概述,搜索不受研究类型的限制.两名审稿人独立评估标题和摘要。排除与儿童无关的记录后,对全文进行筛选纳入。任何判断上的差异都是通过与第三名审稿人讨论来解决的。
    在35个相关标题中,这次审查中包括22人。只有4篇文章提供了有关长期结果的信息。审查的总体质量被认为较低。大多数报告没有涉及心理和社会领域的治疗或教育。由于数据的实质性异质性,结构定性分析是不可行的。
    支持当前ACNES儿童治疗策略的证据质量较低。需要更多的研究来为患有这种具有挑战性的疼痛问题的患者建立基于证据的治疗算法。根据世卫组织的建议,应该更加重视生物心理社会方法。最终目标应该是开发通用治疗算法,概述适用于所有相关专业人员的ACNES方法。
    UNASSIGNED: Evidence-based guidelines for managing anterior cutaneous nerve entrapment syndrome (ACNES) in children are absent. The primary aim of this review was to scrutinize the evidence supporting currently used treatment interventions. In accordance with the World Health Organization (WHO) guidelines for managing chronic pain in children, these patients and their families and caregivers should be treated within the context of the biopsychosocial model; pain should not be treated purely as a biomedical problem. Therefore, our second aim was to evaluate whether these interventions are applied within the context of the biopsychosocial model, utilizing an inter- or multidisciplinary approach.
    UNASSIGNED: A scoping review of the literature was conducted to explore treatment strategies for ACNES in children. To ensure a comprehensive overview of published literature on this topic, the search was not restricted based on study type. Two reviewers independently assessed titles and abstracts. After excluding records unrelated to children, full texts were screened for inclusion. Any discrepancies in judgement were resolved through discussion with a third reviewer.
    UNASSIGNED: Out of 35 relevant titles, 22 were included in this review. Only 4 articles provided information on long-term outcomes. The overall quality of the review was deemed low. The majority of reports did not address treatment or education within the psychological and social domains. A structural qualitative analysis was not feasible due to the substantial heterogeneity of the data.
    UNASSIGNED: The evidence supporting current treatment strategies in children with ACNES is of low quality. More research is needed to establish an evidence-based treatment algorithm for patients with this challenging pain problem. In line with the WHO recommendation, greater emphasis should be placed on a biopsychosocial approach. The ultimate goal should be the development of a generic treatment algorithm outlining an approach to ACNES applicable to all professionals involved.
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  • 文章类型: Journal Article
    下肢压迫性神经病是一种被误解和未被诊断的疾病,以疼痛和感觉障碍为特征,肌肉无力,以及体检中特定的挑衅性动作。在临床实践中最常见的这些综合征是腓骨神经卡压,胫骨近端神经病,腓肠神经神经病,臀深综合征或坐骨神经卡压,股外侧皮神经卡压,也被称为meralgia异常。这些通常被误认为是腰丛疾病,神经根病,和肌肉肌腱疾病,出现频率更高,临床表现重叠。一个全面的回忆,体检,和电诊断研究应该有助于澄清诊断。如果诊断仍不清楚或怀疑是导致截留的次要原因,磁共振神经成像,MRI,或超声检查应明确病因,排除其他疾病,并确认诊断。这篇叙述性综述的目的是帮助临床医生熟悉这种疾病,随着诊断信心的增加,导致神经损伤的早期诊断和肌肉萎缩的预防。我们回顾了流行病学,解剖学,病理生理学,病因学,临床表现,和EDX技术和下肢压迫性神经病的解释,使用1970年至2022年出版的文章,MEDLINE,科克伦图书馆,谷歌学者,EMBASE,WebofScience,和Scopus数据库。
    Entrapment neuropathies of the lower limb are a misunderstood and underdiagnosed group of disorders, characterized by pain and dysesthesia, muscular weakness, and specific provoking movements on physical examination. The most frequent of these syndromes encountered in clinical practice are fibular nerve entrapment, proximal tibial neuropathy, sural nerve neuropathy, deep gluteal syndrome or sciatic nerve entrapment, and lateral femoral cutaneous nerve entrapment, also known as meralgia paresthetica. These are commonly mistaken for lumbar plexopathies, radiculopathies, and musculotendinous diseases, which appear even more frequently and have overlapping clinical presentations. A comprehensive anamnesis, physical examination, and electrodiagnostic studies should help clarify the diagnosis. If the diagnosis is still unclear or a secondary cause of entrapment is suspected, magnetic resonance neurography, MRI, or ultrasonography should be conducted to clarify the etiology, rule out other diseases, and confirm the diagnosis. The aim of this narrative review was to help clinicians gain familiarity with this disease, with an increase in diagnostic confidence, leading to early diagnosis of nerve damage and prevention of muscle atrophy. We reviewed the epidemiology, anatomy, pathophysiology, etiology, clinical presentation, and EDX technique and interpretation of the entrapment neuropathies of the lower limb, using articles published from 1970 to 2022 included in the Pubmed, MEDLINE, Cochrane Library, Google Scholar, EMBASE, Web of Science, and Scopus databases.
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  • 文章类型: Case Reports
    子宫肌瘤是育龄期妇女中最常见的妇科肿瘤,患病率高达80%。症状可以从大量阴道出血和大量症状到,不那么频繁,深静脉血栓形成和肠梗阻。
    一名32岁女性患者出现急性右腹股沟和膝关节疼痛,和行走困难。发现一个巨大的子宫后肌瘤压迫了腰丛的分支,包括闭孔神经.该患者接受了妇科评估和紧急腹腔镜子宫肌瘤切除术。术后,她的神经系统症状有了显著改善.她继续进行物理治疗,以治疗残留的轻度感觉异常和长时间行走的疼痛。
    对于急性非妇科症状,如压迫性神经病,在鉴别诊断时,应考虑子宫肌瘤等盆腔大肿块,这需要紧急评估和可能的手术管理。
    Uterine fibroids are the most common gynecologic tumors in reproductive-aged women with a prevalence of up to 80%. Symptoms can range from heavy vaginal bleeding and bulk symptoms to, less frequently, deep vein thrombosis and bowel obstruction.
    A 32-year-old female patient presented with acute-onset of right groin and knee pain, and difficulty ambulating. A large posterior uterine fibroid was found to be compressing branches of the lumbar plexus, including the obturator nerve. The patient underwent gynecologic evaluation and an urgent laparoscopic myomectomy. Postoperatively, she had significant improvement in neurologic symptoms. She continued physical therapy for residual mild paresthesia and pain with prolonged ambulation.
    Large pelvic masses such as uterine fibroids should be considered on the differential diagnosis for acute-onset non-gynecologic symptoms such as compressive neuropathy, which require urgent evaluation and possible surgical management.
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  • 文章类型: Journal Article
    骨科手术界罕见但通常被忽视的诊断是上肌腱神经(SCN)卡压综合征。肘部神经的功能是纯粹的感觉纤维,SCNs为后骶骨提供皮肤神经支配,臀肌,和大腿后外侧区域。当被激怒时,这种综合征可引起急性和慢性下背部疼痛和下肢症状。一名14岁的青春期女孩出现在诊所,以评估她下背部右侧的疼痛。患者的体格检查显示,在距中线7厘米的右后髂关节触诊有压痛。她的神经系统检查显示深肌腱反射正常,肌肉力量,和L2-S1皮肌分布中的感觉。尽管影像学显示有左L5峡部裂的证据,她对髂后骨上的类固醇注射反应积极,但对L5条缺损上的类固醇注射反应消极。她后来接受了右SCN减压手术。手术后,她报告说疼痛至少改善了90%,并将其评为严重程度,在0到10的范围内。在过去的几年中,有关SCN诱捕综合征的研究有所增加。然而,这些研究大多仅限于成年人群。因此,还需要更多的报告强调这种综合征在青少年中的可能性。
    A rare but typically overlooked diagnosis in the orthopaedic surgery community is superior cluneal nerve (SCN) entrapment syndrome. The cluneal nerves function as purely sensory fibers, and the SCNs provide cutaneous innervation to the posterior parasacral, gluteal, and posterolateral thigh regions. When irritated, this syndrome can cause acute and chronic lower back pain and lower extremity symptoms. A 14-year-old adolescent girl presented to the clinic for an evaluation of pain in the right side of her lower back. The patient\'s physical examination showed tenderness to palpation on the right posterior iliac crest seven centimeters from the midline. Her neurologic examination demonstrated normal deep tendon reflexes, muscle strength, and sensation in the L2-S1 dermatomal distribution. Although imaging showed evidence of a left L5 spondylolysis, she responded positively to a steroid injection over the posterior iliac crest but negatively to one over the L5 pars defect. She later underwent a right SCN decompression surgery. After the procedure, she reported at least 90% improvement in her pain and rated it as a one in severity, on a scale of 0 to 10. Research regarding SCN entrapment syndrome has increased in the past several years. However, most of these studies are limited to the adult population. Therefore, more reports highlighting the potential for this syndrome in adolescents are needed as well.
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