Minimally invasive cardiac Surgery

微创心脏手术
  • 文章类型: Journal Article
    背景:EuroSCOREII(ES2)是心脏手术前死亡率风险预测的可靠工具;然而,病人的年龄,外科手术的重量和可用的新设备可能会导致其准确性漂移。我们试图调查ES2性能与手术风险和晚期死亡率估计相关的患者主动脉瓣置换术(AVR)无缝合瓣膜。方法:在2012年至2021年之间,回顾性收集了来自六个欧洲中心的1126例单纯性主动脉瓣狭窄患者,这些患者通过无缝合瓣膜进行了AVR手术。根据EuroSCOREII风险等级将患者分为三组(ES2<4%,ES24-8%和ES2>8%)。使用标准化死亡率比(O/E比)评估ES2估计死亡风险的准确性,ROC曲线(AUC)和Hosmer-Lemeshow(HL)检验拟合优度。结果:总体观察死亡率为3.0%(预测死亡率ES2:5.39%),观察/预期(O/E)比为0.64(保密区间(CI):0.49-0.89)。在我们的人口中,ES2显示中等辨别能力(AUC0.65,95CI0.56-0.72,p<0.001;HLp=0.798)。ES2<4%的患者(O/E比0.54,95CI0.23-1.20,AUC0.75,p<0.001,HLp=0.999)和年龄<75岁的患者(O/E比0.98,95CI0.45-1.96,AUC0.76,p=0.004,HLp=0.762)具有良好的准确性。ES2在估计长期死亡风险方面观察到中度区分(AUC0.64,95CI:0.60-0.68,p<0.001)。结论:EuroSCOREII在年龄<75岁和ES2<4%的患者中显示出良好的准确性,同时高估了其他亚组的风险。应根据实际患者的复杂性和新技术的影响考虑模型的重新校准。
    Background: EuroSCORE II (ES2) is a reliable tool for preoperative cardiac surgery mortality risk prediction; however, a patient\'s age, a surgical procedure\'s weight and the new devices available may cause its accuracy to drift. We sought to investigate ES2 performance related to the surgical risk and late mortality estimation in patients who underwent aortic valve replacement (AVR) with sutureless valves. Methods: Between 2012 and 2021, a total of 1126 patients with isolated aortic stenosis who underwent surgical AVR by means of sutureless valves were retrospectively collected from six European centers. Patients were stratified into three groups according to the EuroSCORE II risk classes (ES2 < 4%, ES2 4-8% and ES2 > 8%). The accuracy of ES2 in estimating mortality risk was assessed using the standardized mortality ratio (O/E ratio), ROC curves (AUC) and Hosmer-Lemeshow (HL) test for goodness-of-fit. Results: The overall observed mortality was 3.0% (predicted mortality ES2: 5.39%) with an observed/expected (O/E) ratio of 0.64 (confidential interval (CI): 0.49-0.89). In our population, ES2 showed a moderate discriminating power (AUC 0.65, 95%CI 0.56-0.72, p < 0.001; HL p = 0.798). Good accuracy was found in patients with ES2 < 4% (O/E ratio 0.54, 95%CI 0.23-1.20, AUC 0.75, p < 0.001, HL p = 0.999) and for patients with an age < 75 years (O/E ratio 0.98, 95%CI 0.45-1.96, AUC 0.76, p = 0.004, HL p = 0.762). Moderate discrimination was observed for ES2 in the estimation of long-term risk of mortality (AUC 0.64, 95%CI: 0.60-0.68, p < 0.001). Conclusions: EuroSCORE II showed good accuracy in patients with an age < 75 years and patients with ES2 < 4%, while overestimating risk in the other subgroups. A recalibration of the model should be taken into account based on the complexity of actual patients and impact of new technologies.
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  • 文章类型: Journal Article
    微创技术的发展和采用,使各种外科学科发生了革命性的变化,也被引入心脏外科,与传统的胸骨切开心脏直视手术相比,为患者提供更少侵入性的选择,减少创伤和更快的恢复时间。本文全面概述了微创心脏手术(MICS)的麻醉管理,专注于术前评估,术中麻醉技术,和术后护理方案。麻醉诱导和气道管理策略是根据每个患者的需求量身定制的,一丝不苟地注意保持血流动力学稳定和确保充分的通气。术中监测,包括经食管超声心动图(TEE),经过处理的脑电图监测,和近红外光谱(NIRS),便于实时评估心脏和大脑灌注,以及功能,优化患者安全并改善预后。描述了用于体外循环(CPB)启动的外周插管技术,强调插管放置的重要性,以尽量减少组织和血管创伤和优化灌注。本文还讨论了具体的MICS程序,详细介绍麻醉注意事项和手术技术。接受MICS的患者的围手术期护理需要包括外科医生在内的多学科方法,灌注主义者,和麻醉医师坚持标准化的治疗方案和途径。通过利用先进的监测技术和量身定制的麻醉方案,临床医生可以优化患者预后,促进早期拔管和加快康复.
    The development and adoption of minimally invasive techniques has revolutionized various surgical disciplines and has also been introduced into cardiac surgery, offering patients less invasive options with reduced trauma and faster recovery time compared to traditional open-heart procedures with sternotomy. This article provides a comprehensive overview of the anesthesiologic management for minimally invasive cardiac surgery (MICS), focusing on preoperative assessment, intraoperative anesthesia techniques, and postoperative care protocols. Anesthesia induction and airway management strategies are tailored to each patient\'s needs, with meticulous attention to maintaining hemodynamic stability and ensuring adequate ventilation. Intraoperative monitoring, including transesophageal echocardiography (TEE), processed EEG monitoring, and near-infrared spectroscopy (NIRS), facilitates real-time assessment of cardiac and cerebral perfusion, as well as function, optimizing patient safety and improving outcomes. The peripheral cannulation techniques for cardiopulmonary bypass (CPB) initiation are described, highlighting the importance of cannula placement to minimize tissue as well as vessel trauma and optimize perfusion. This article also discusses specific MICS procedures, detailing anesthetic considerations and surgical techniques. The perioperative care of patients undergoing MICS requires a multidisciplinary approach including surgeons, perfusionists, and anesthesiologists adhering to standardized treatment protocols and pathways. By leveraging advanced monitoring techniques and tailored anesthetic protocols, clinicians can optimize patient outcomes and promote early extubation and enhanced recovery.
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  • 文章类型: Journal Article
    乳内动脉(IMA)是冠状动脉旁路移植术(CABG)中最常用的移植物,因为它具有优越的长期通畅率。然而,它的小直径带来了处理方面的挑战,在手术期间可能发生的任何血管损伤都会显著影响手术结果。IMA采集期间的主要重点是确保安全和有效的止血,而不会直接损伤血管。同时确保血管分支的安全可靠结扎。使用多个外科器械的各种方法已经用于此目的。与传统乐器不同,剪切尖端谐波手术刀提供更精确的血管分支控制,同时尽量减少对周围组织的损害。在这项研究中,我们评估了剪切尖端谐波手术刀在微创冠状动脉旁路移植术(MICABG)患者中的应用价值.
    从2019年4月到2023年5月,共有40名患者接受了MICABG。IMA是使用剪切尖端谐波手术刀和无夹骨架技术采集的。在这个队列中,5例患者接受了完整的内窥镜采集,而34例患者通过最小开胸手术进行了直接可视化采集。通过测量旁路导管中的多普勒流量计来评估移植物通畅性。
    所有患者均获得了成功的移植物通畅。IMA收获的平均持续时间为87分钟。总的来说,40名患者中有38名在不需要体外循环的情况下接受了MICABG,确保程序稳定。在任何患者中均未观察到移植物相关事件或并发症,都出院了,没有任何问题。在15.2个月的中位随访期间,只有一名患者经历了需要干预的移植物闭塞。
    在MICABG中使用剪切尖端谐波手术刀进行IMA采集是可行的,并产生稳定的早期结果。
    UNASSIGNED: The internal mammary artery (IMA) is the most commonly used graft in coronary artery bypass grafting (CABG) because of its superior long-term patency rate. However, its small diameter poses challenges in handling, and any vascular damage that may occur during harvesting can significantly affect surgical outcomes. The primary focus during IMA harvesting is to ensure safe and effective hemostasis without direct vascular injury, while ensuring secure and reliable ligation of the vascular branches. Various methods using multiple surgical instruments have been used for this purpose. Unlike traditional instruments, the shear-tip Harmonic scalpel offers more precise vessel branching control, while minimizing damage to surrounding tissues. In this study, we assessed the utility of the shear-tip Harmonic scalpel in patients undergoing minimally invasive coronary artery bypass grafting (MICABG).
    UNASSIGNED: From April 2019 to May 2023, a total of 40 patients underwent MICABG. The IMA was harvested using the shear-tip Harmonic scalpel with a clipless skeletonized technique. In this cohort, 5 patients underwent complete endoscopic harvesting, while 34 patients underwent direct visualization harvesting through minimal thoracotomy. Graft patency was assessed by measuring a Doppler flowmeter in the bypass conduit.
    UNASSIGNED: Successful graft patency was achieved in all patients. The mean duration of IMA harvesting was 87 min. In total, 38 of the 40 patients underwent MICABG without the need for cardiopulmonary bypass, ensuring a stable procedure. There were no graft-related events or complications observed in any of the patients, and all were discharged without any issues. During a median follow-up period of 15.2 months, only one patient experienced graft occlusion necessitating intervention.
    UNASSIGNED: The utilization of shear-tip Harmonic scalpel for IMA harvesting in MICABG is feasible and yields stable early results.
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  • 文章类型: Journal Article
    目的:评估微创心脏手术(MICS)与胸骨切开术对无法接受输血的耶和华见证人(JW)患者的治疗效果。设计:这是一项回顾性观察性研究。
    方法:这项研究是在专门的心血管介入和外科研究所进行的。
    方法:研究队列包括2016年9月至2022年7月接受心脏手术的JW患者。
    方法:无测量和主要结果:患者(n=63)分为MICS(n=19)和胸骨切开术(n=44)组,并对临床结局进行分析。除冠状动脉旁路移植术外,手术类型无差异(MICS组n=1[5.3%]v胸骨切开术组n=20[45.5%];p=0.005)。早期死亡率和发病率没有组间差异。在随访期间,总生存率没有显着差异(平均值,43.9±24.4个月)。术后第一天,MICS组的胸管引流量显着降低(平均值,胸骨切开术组224.0±122.7mLv334.0±187.0mL;p=0.022)。MICS组手术当天的平均血红蛋白水平明显高于胸骨切开术组(11.7±1.3mg/dLv10.6±2.0mg/dL;p=0.042)和术后第一天(12.3±1.8mg/dLv11.2±1.9mg/dL;p=0.032)。
    结论:与常规胸骨切开术相比,JW患者的MICS显示出良好的早期结局和中期生存率。MICS可能是拒绝输血的JW患者的可行选择。
    OBJECTIVE: To evaluate the outcomes of minimally invasive cardiac surgery (MICS) compared with the sternotomy approach for Jehovah\'s Witness (JW) patients who cannot receive blood transfusions DESIGN: This was a retrospective observational study.
    METHODS: The study was conducted at a specialized cardiovascular intervention and surgery institute.
    METHODS: The study cohort comprised JW patients undergoing cardiac surgery between September 2016 and July 2022.
    METHODS: None MEASUREMENTS AND MAIN RESULTS: Patients (n = 63) were divided into MICS (n = 19) and sternotomy (n = 44) groups, and clinical outcomes were analyzed. There was no difference in types of operation except coronary bypass grafting (n = 1 [5.3%] in the MICS group v n = 20 [45.5%] in the sternotomy group; p = 0.005). There were no between-group differences in early mortality and morbidities. Overall survival did not differ significantly during the follow-up period (mean, 43.9 ± 24.4 months). The amount of chest tube drainage was significantly lower in the MICS group on the first postoperative day (mean, 224.0 ± 122.7 mL v 334.0 ± 187.0 mL in the sternotomy group; p = 0.022). The mean hemoglobin level was significantly higher in the MICS group on the day of operation (11.7 ± 1.3 mg/dL v 10.6 ± 2.0 mg/dL in the sternotomy group; p = 0.042) and the first postoperative day (12.3 ± 1.8 mg/dL v 11.2 ± 1.9 mg/dL; p = 0.032).
    CONCLUSIONS: MICS for JW patients showed favorable early outcomes and mid-term survival compared to conventional sternotomy. MICS may be a viable option for JW patients who decline blood transfusions.
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  • 文章类型: Journal Article
    机器人辅助的微创直接冠状动脉搭桥术(RA-MIDCAB)是冠状动脉血运重建的一种有吸引力的策略。越来越多的证据支持在冠状动脉手术中使用全动脉移植。我们使用RA-MIDCAB评估了双侧胸廓内动脉(BITA)的总动脉左侧冠状动脉血运重建,并将其与倾向评分匹配(PSM)非体外循环CAB(OPCAB)手术人群进行了比较。
    我们回顾性纳入了2015年1月1日至2022年10月31日使用BITA进行的所有孤立的OPCAB和RA-MIDCAB手术,而没有进行大隐静脉移植。我们分析了所有RA-MIDCAB患者,并进行了PSM,以将其与我们的OPCAB人群进行比较。主要结局是主要不良心脑血管事件(MACCE)和死亡率。次要结果是手术参数,住院时间,和学习曲线。
    我们包括601OPCAB和77RA-MIDCAB程序,这导致2个队列的54名患者PSM后。死亡率和MACCE生存分析显示无显著差异。与OPCAB组(38.9%;P=0.02)相比,RA-MIDCAB组的输血减少(16.7%)。我们观察到重症监护病房(ICU)入院人数减少(24.1%vs96.6%),ICU住院时间较短(0.78±1.7vs1.91±1.01天),RA-MIDCAB与OPCAB组的住院时间较短(6.78±2.4vs8.01±2.5天)(P<0.01)。手术时间从400.0±70.8降至325.0±38.0min,RA-MIDCABBITA采集经验更多(P<0.01)。
    这是用于左冠状动脉系统血运重建的77份连续RA-MIDCABBITA采集的第一份出版物。该技术在MACCE和死亡率方面是安全的。其他优点是住院时间短,ICU入院人数减少,减少输血。
    UNASSIGNED: Robot-assisted minimally invasive direct coronary artery bypass (RA-MIDCAB) is an attractive strategy for coronary revascularization. Growing evidence supports the use of total arterial grafting in coronary surgery. We evaluated total arterial left-sided coronary revascularization with bilateral internal thoracic artery (BITA) using RA-MIDCAB and compared it with a propensity score-matched (PSM) off-pump CAB (OPCAB) surgery population.
    UNASSIGNED: We retrospectively included all isolated OPCAB and RA-MIDCAB surgery using BITA without saphenous vein graft from January 1, 2015, to October 31, 2022. We analyzed all our RA-MIDCAB patients and performed PSM to compare them with our OPCAB population. Primary outcomes were major adverse cardiovascular and cerebrovascular events (MACCE) and mortality. Secondary outcomes were surgical parameters, length of hospital stay, and learning curve.
    UNASSIGNED: We included 601 OPCAB and 77 RA-MIDCAB procedures, which resulted in 2 cohorts of 54 patients after PSM. Mortality and MACCE survival analysis showed no significant difference. There was less blood transfusion in the RA-MIDCAB (16.7%) compared with the OPCAB group (38.9%; P = 0.02). We observed fewer intensive care unit (ICU) admissions (24.1% vs 96.6%), shorter ICU stay (0.78 ± 1.7 vs 1.91 ± 1.01 days), and shorter hospital stay (6.78 ± 2.4 vs 8.01 ± 2.5 days) in the RA-MIDCAB versus OPCAB group (P < 0.01). Surgery time decreased from 400.0 ± 70.8 to 325.0 ± 38.0 min with more experience in RA-MIDCAB BITA harvesting (P < 0.01).
    UNASSIGNED: This is a first publication of 77 consecutive RA-MIDCAB BITA harvesting for left coronary artery system revascularization. This technique is safe in terms of MACCE and mortality. Additional advantages are shorter length of hospital stay, fewer ICU admissions, and less blood transfusion.
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  • 文章类型: Journal Article
    背景:历史上,大多数接受基于运动的心脏康复(EBCR)的住院患者接受了心脏直视手术(OHS).然而,随着微创心脏手术(MICS)的进步,这些患者群体也越来越多地因住院EBCR而被提及.在这里,我们旨在比较这些群体在康复期间的进展。
    方法:在此前瞻性中,非随机研究,从2022年12月至2023年9月招募了403名住院EBCR患者,并将其分为两组:OHS,和MICS。参与者完成了3-4周认证的EBCR计划。主要终点定义为6分钟步行试验(6MWT)的变化。此外,在入院和出院时进行全面的生活质量(QoL)评估.
    结果:在基线时,OHS患者年龄较大(66岁[IQR59-72]),更常见的是男性(83%),与MICS患者相比,接受急诊/紧急手术的频率更高(20%)。此外,与OHS患者(381米[IQR299-453])相比,MICS患者在入院时显示出更好的6MWT(426米[IQR336-483]).虽然所有患者都能够增加6MWT的距离,在完全校正模型中进行的回归分析显示,两组间的改善无差异(β-5,95%CI,-26-14,p=0.58).此外,在EBCR期间,我们观察到所有组的所有QoL指标均有显著改善.
    结论:在这项研究中,改善健身,通过6WMT评估,在所有组中观察到。此外,多个QoL指标在所有组中的改善程度相同。这些令人鼓舞的结果强调了EBCR的重要性。
    BACKGROUND: Historically, the majority of patients admitted to inpatient exercise-based cardiac rehabilitation (EBCR) have undergone open heart surgery (OHS). However, with advances in minimally invasive cardiac surgery (MICS), these patient groups are also increasingly referred for inpatient EBCR. Herein, we aimed to compare the progress of these groups during rehabilitation.
    METHODS: In this prospective, nonrandomized study, 403 inpatient EBCR patients were recruited from December 2022 until September 2023 and stratified into two groups: OHS, and MICS. Participants completed a 3-4-week certified EBCR program. The primary endpoint was defined as a change in the 6-minute walk test (6MWT). Moreover, a comprehensive panel of quality-of-life (QoL) assessments were performed at admission and discharge.
    RESULTS: At baseline, patients with OHS were older (66 years [IQR 59 - 72]), more often male (83%), and underwent emergency/urgent procedures more often (20%) than patients with MICS. Furthermore, patients with MICS showed a better 6MWT at admission (426 meters [IQR 336 - 483]) compared to patients with OHS (381 meters [IQR 299 - 453]). While all patients were able to increase the distance in the 6MWT, regression analyses in fully adjusted models showed no difference in improvements between the two groups (β -5, 95% CI, -26 - 14, p = 0.58). Moreover, during EBCR, we observed significant improvements in all QoL measures in all groups.
    CONCLUSIONS: In this study, improvements in fitness, as assessed by the 6WMT were observed in all groups. Furthermore, multiple QoL measures improved equally across all groups. These encouraging results emphasize the importance of EBCR.
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  • 文章类型: Case Reports
    微创心脏手术非体外循环冠状动脉搭桥术(MICSOPCAB)已变得越来越普遍,心脏定位器等设备有助于手术精度。然而,罕见的并发症如心外膜血肿可发生。这里,我们介绍一例75岁接受MICSOPCAB治疗的男性患者,该患者因心脏定位器而出现心外膜血肿.术中通过直接缝合和大毛毡成功修复了血肿。术后恢复顺利,强调警惕监测和及时管理此类并发症的重要性。这种情况强调了在使用心脏定位器期间需要仔细注意,以最大程度地减少不良事件并确保良好的患者预后。
    Minimally invasive cardiac surgery off-pump coronary artery bypass (MICSOPCAB) has become increasingly prevalent, with devices like the heart positioner aiding in surgical precision. However, rare complications such as epicardial hematoma can occur. Here, we present a case of a 75-year-old man undergoing MICSOPCAB who developed an epicardial hematoma due to the heart positioner. The hematoma was successfully repaired intraoperatively with direct suturing and large felts. Postoperative recovery was uneventful, highlighting the importance of vigilant monitoring and prompt management of such complications. This case underscores the need for careful attention during the use of cardiac positioners to minimize adverse events and ensure favorable patient outcomes.
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  • 文章类型: Journal Article
    目标:微创直接冠状动脉搭桥术(MIDCAB)是孤立的左前降支(LAD)动脉血运重建的替代方法,也可以作为对角支(RD)或左回旋支(LCX)区域的多血管(MV)手术。方法:从2021年到2022年,91例患者在我们的心脏中心接受了MIDCAB或多血管MIDCAB手术。所有患者均通过左胸小切口手术将左乳内动脉(LIMA)与左前降支吻合。结果:在患者中,共有86.8%为男性。80%的患者患有两支或三支冠状动脉疾病。平均年龄为65.1±10.1岁。平均手术时间为2.6±0.8h。30天死亡率为0。平均所需的压积红细胞(pRBC)为0.4±1.2单位。重症监护病房(ICU)平均住院时间为1.5±1.6天。平均随访时间为1.5±0.5年。由于RCA的新狭窄,一名患者接受了经皮冠状动脉介入治疗。晚期死亡率为2.2%。Kaplan-Meier1年和2年生存率为98.8%。结论:我们的MIDCAB队列的术后并发症发生率较低,短期生存是有利的。我们的术后和短期临床结果表明,该程序是安全可行的。
    Objectives: Minimally invasive direct coronary artery bypass (MIDCAB) is an alternative for revascularisation of the isolated left anterior descending (LAD) artery or as a multi-vessel (MV) procedure for the diagonal branch (RD) or the left circumflex coronary artery (LCX) region. Methods: From 2021 to 2022, 91 patients underwent MIDCAB or multi-vessel MIDCAB procedures in our heart center. The left internal mammary artery (LIMA) was anastomosed to the left anterior descending artery via the left minithoracotomy approach in all patients. Results: Of the patients, a total of 86.8% were male. Eighty percent of the patients had two- or three-vessel coronary artery disease. The mean age was 65.1 ± 10.1 years. The mean operation time was 2.6 ± 0.8 h. The 30-day mortality was 0. The mean required packed red blood cells (pRBC) was 0.4 ± 1.2 unit. The mean intensive care unit stay (ICU) was 1.5 ± 1.6 days. The mean follow-up time was 1.5 ± 0.5 years. One patient received percutaneous coronary intervention due to de novo stenosis of the RCA. Late mortality was 2.2%. The Kaplan-Meier survival rate was 98.8% at 1 and 2 years. Conclusions: The postoperative complication rate of our MIDCAB cohort is low, and the short-term survival is favorable. Our postoperative and short-term clinical results demonstrate that this procedure is safe and feasible.
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  • 文章类型: Editorial
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  • 文章类型: Journal Article
    背景:狭窄胸部对微创二尖瓣手术(MIMVS)的影响尚不清楚。方法和结果:我们招募了206例MIMVS患者,并测量了胸骨和椎骨之间的前后直径(APD)。胸横径(TD),右和左胸侧APD(RD和LD,分别),和计算机断层扫描的哈勒指数(HI;TD/APD比)。比较胸部狭窄患者(N组;HI>2.5;n=53)和胸部正常患者(对照组[C];HI≤2.5;n=153)的术前特征和手术结果,并在133例接受隔离二尖瓣手术的患者中评估了这些测量值与手术时间的相关性。N组和C组在APD上存在显着差异(89.4vs.114.3mm,分别为;P<0.001),TD(251.5vs.240.3mm,分别为;P=0.002),RD(152.5vs.172.5mm,分别为;P<0.001),LD(155.0vs.172.4mm,分别为;P<0.001),和HI(2.84vs.分别为2.12;P<0.001)。程序特征相当,除了N组的主动脉交叉钳夹时间(ACCT)更长(118.7vs.105.8min;P=0.047)。手术死亡率,重新探索,脑梗塞,两组之间的通气时间相当。在接受隔离二尖瓣手术的患者中,TD与ACCT显着相关(R2=0.037,P=0.028)。
    结论:胸部狭窄患者的早期MIMVS结果令人满意。TD在MIMVS期间延长ACCT。
    BACKGROUND: The effect of a narrow chest on minimally invasive mitral valve surgery (MIMVS) is unclear.Methods and Results: We enrolled 206 MIMVS patients and measured anteroposterior diameter (APD) between the sternum and vertebra, transverse thoracic diameter (TD), right and left APD of the hemithorax (RD and LD, respectively), and the Haller index (HI; TD/APD ratio) on computed tomography. Preoperative characteristics and operative outcomes were compared between patients with a narrow chest (Group N; HI >2.5; n=53) and those with a normal chest (control [C]; HI ≤2.5; n=153), and the correlations of these measurements with operation time were evaluated in 133 patients undergoing an isolated mitral procedure. Groups N and C differed significantly in APD (89.4 vs. 114.3 mm, respectively; P<0.001), TD (251.5 vs. 240.3 mm, respectively; P=0.002), RD (152.5 vs. 172.5 mm, respectively; P<0.001), LD (155.0 vs. 172.4 mm, respectively; P<0.001), and HI (2.84 vs. 2.12, respectively; P<0.001). Procedural characteristics were comparable, except for a longer aortic cross-clamp time (ACCT) in Group N (118.7 vs. 105.8 min; P=0.047). Rates of surgical death, re-exploration, cerebral infarction, and prolonged ventilation were comparable between the 2 groups. TD was significantly correlated with ACCT (R2=0.037, P=0.028) in patients undergoing an isolated mitral procedure.
    CONCLUSIONS: Early MIMVS outcomes in patients with narrow chests are satisfactory. TD prolongs ACCT during MIMVS.
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