Minimally invasive cardiac Surgery

微创心脏手术
  • 文章类型: Journal Article
    乳内动脉(IMA)是冠状动脉旁路移植术(CABG)中最常用的移植物,因为它具有优越的长期通畅率。然而,它的小直径带来了处理方面的挑战,在手术期间可能发生的任何血管损伤都会显著影响手术结果。IMA采集期间的主要重点是确保安全和有效的止血,而不会直接损伤血管。同时确保血管分支的安全可靠结扎。使用多个外科器械的各种方法已经用于此目的。与传统乐器不同,剪切尖端谐波手术刀提供更精确的血管分支控制,同时尽量减少对周围组织的损害。在这项研究中,我们评估了剪切尖端谐波手术刀在微创冠状动脉旁路移植术(MICABG)患者中的应用价值.
    从2019年4月到2023年5月,共有40名患者接受了MICABG。IMA是使用剪切尖端谐波手术刀和无夹骨架技术采集的。在这个队列中,5例患者接受了完整的内窥镜采集,而34例患者通过最小开胸手术进行了直接可视化采集。通过测量旁路导管中的多普勒流量计来评估移植物通畅性。
    所有患者均获得了成功的移植物通畅。IMA收获的平均持续时间为87分钟。总的来说,40名患者中有38名在不需要体外循环的情况下接受了MICABG,确保程序稳定。在任何患者中均未观察到移植物相关事件或并发症,都出院了,没有任何问题。在15.2个月的中位随访期间,只有一名患者经历了需要干预的移植物闭塞。
    在MICABG中使用剪切尖端谐波手术刀进行IMA采集是可行的,并产生稳定的早期结果。
    UNASSIGNED: The internal mammary artery (IMA) is the most commonly used graft in coronary artery bypass grafting (CABG) because of its superior long-term patency rate. However, its small diameter poses challenges in handling, and any vascular damage that may occur during harvesting can significantly affect surgical outcomes. The primary focus during IMA harvesting is to ensure safe and effective hemostasis without direct vascular injury, while ensuring secure and reliable ligation of the vascular branches. Various methods using multiple surgical instruments have been used for this purpose. Unlike traditional instruments, the shear-tip Harmonic scalpel offers more precise vessel branching control, while minimizing damage to surrounding tissues. In this study, we assessed the utility of the shear-tip Harmonic scalpel in patients undergoing minimally invasive coronary artery bypass grafting (MICABG).
    UNASSIGNED: From April 2019 to May 2023, a total of 40 patients underwent MICABG. The IMA was harvested using the shear-tip Harmonic scalpel with a clipless skeletonized technique. In this cohort, 5 patients underwent complete endoscopic harvesting, while 34 patients underwent direct visualization harvesting through minimal thoracotomy. Graft patency was assessed by measuring a Doppler flowmeter in the bypass conduit.
    UNASSIGNED: Successful graft patency was achieved in all patients. The mean duration of IMA harvesting was 87 min. In total, 38 of the 40 patients underwent MICABG without the need for cardiopulmonary bypass, ensuring a stable procedure. There were no graft-related events or complications observed in any of the patients, and all were discharged without any issues. During a median follow-up period of 15.2 months, only one patient experienced graft occlusion necessitating intervention.
    UNASSIGNED: The utilization of shear-tip Harmonic scalpel for IMA harvesting in MICABG is feasible and yields stable early results.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    背景:历史上,大多数接受基于运动的心脏康复(EBCR)的住院患者接受了心脏直视手术(OHS).然而,随着微创心脏手术(MICS)的进步,这些患者群体也越来越多地因住院EBCR而被提及.在这里,我们旨在比较这些群体在康复期间的进展。
    方法:在此前瞻性中,非随机研究,从2022年12月至2023年9月招募了403名住院EBCR患者,并将其分为两组:OHS,和MICS。参与者完成了3-4周认证的EBCR计划。主要终点定义为6分钟步行试验(6MWT)的变化。此外,在入院和出院时进行全面的生活质量(QoL)评估.
    结果:在基线时,OHS患者年龄较大(66岁[IQR59-72]),更常见的是男性(83%),与MICS患者相比,接受急诊/紧急手术的频率更高(20%)。此外,与OHS患者(381米[IQR299-453])相比,MICS患者在入院时显示出更好的6MWT(426米[IQR336-483]).虽然所有患者都能够增加6MWT的距离,在完全校正模型中进行的回归分析显示,两组间的改善无差异(β-5,95%CI,-26-14,p=0.58).此外,在EBCR期间,我们观察到所有组的所有QoL指标均有显著改善.
    结论:在这项研究中,改善健身,通过6WMT评估,在所有组中观察到。此外,多个QoL指标在所有组中的改善程度相同。这些令人鼓舞的结果强调了EBCR的重要性。
    BACKGROUND: Historically, the majority of patients admitted to inpatient exercise-based cardiac rehabilitation (EBCR) have undergone open heart surgery (OHS). However, with advances in minimally invasive cardiac surgery (MICS), these patient groups are also increasingly referred for inpatient EBCR. Herein, we aimed to compare the progress of these groups during rehabilitation.
    METHODS: In this prospective, nonrandomized study, 403 inpatient EBCR patients were recruited from December 2022 until September 2023 and stratified into two groups: OHS, and MICS. Participants completed a 3-4-week certified EBCR program. The primary endpoint was defined as a change in the 6-minute walk test (6MWT). Moreover, a comprehensive panel of quality-of-life (QoL) assessments were performed at admission and discharge.
    RESULTS: At baseline, patients with OHS were older (66 years [IQR 59 - 72]), more often male (83%), and underwent emergency/urgent procedures more often (20%) than patients with MICS. Furthermore, patients with MICS showed a better 6MWT at admission (426 meters [IQR 336 - 483]) compared to patients with OHS (381 meters [IQR 299 - 453]). While all patients were able to increase the distance in the 6MWT, regression analyses in fully adjusted models showed no difference in improvements between the two groups (β -5, 95% CI, -26 - 14, p = 0.58). Moreover, during EBCR, we observed significant improvements in all QoL measures in all groups.
    CONCLUSIONS: In this study, improvements in fitness, as assessed by the 6WMT were observed in all groups. Furthermore, multiple QoL measures improved equally across all groups. These encouraging results emphasize the importance of EBCR.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Case Reports
    微创心脏手术非体外循环冠状动脉搭桥术(MICSOPCAB)已变得越来越普遍,心脏定位器等设备有助于手术精度。然而,罕见的并发症如心外膜血肿可发生。这里,我们介绍一例75岁接受MICSOPCAB治疗的男性患者,该患者因心脏定位器而出现心外膜血肿.术中通过直接缝合和大毛毡成功修复了血肿。术后恢复顺利,强调警惕监测和及时管理此类并发症的重要性。这种情况强调了在使用心脏定位器期间需要仔细注意,以最大程度地减少不良事件并确保良好的患者预后。
    Minimally invasive cardiac surgery off-pump coronary artery bypass (MICSOPCAB) has become increasingly prevalent, with devices like the heart positioner aiding in surgical precision. However, rare complications such as epicardial hematoma can occur. Here, we present a case of a 75-year-old man undergoing MICSOPCAB who developed an epicardial hematoma due to the heart positioner. The hematoma was successfully repaired intraoperatively with direct suturing and large felts. Postoperative recovery was uneventful, highlighting the importance of vigilant monitoring and prompt management of such complications. This case underscores the need for careful attention during the use of cardiac positioners to minimize adverse events and ensure favorable patient outcomes.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    目标:微创直接冠状动脉搭桥术(MIDCAB)是孤立的左前降支(LAD)动脉血运重建的替代方法,也可以作为对角支(RD)或左回旋支(LCX)区域的多血管(MV)手术。方法:从2021年到2022年,91例患者在我们的心脏中心接受了MIDCAB或多血管MIDCAB手术。所有患者均通过左胸小切口手术将左乳内动脉(LIMA)与左前降支吻合。结果:在患者中,共有86.8%为男性。80%的患者患有两支或三支冠状动脉疾病。平均年龄为65.1±10.1岁。平均手术时间为2.6±0.8h。30天死亡率为0。平均所需的压积红细胞(pRBC)为0.4±1.2单位。重症监护病房(ICU)平均住院时间为1.5±1.6天。平均随访时间为1.5±0.5年。由于RCA的新狭窄,一名患者接受了经皮冠状动脉介入治疗。晚期死亡率为2.2%。Kaplan-Meier1年和2年生存率为98.8%。结论:我们的MIDCAB队列的术后并发症发生率较低,短期生存是有利的。我们的术后和短期临床结果表明,该程序是安全可行的。
    Objectives: Minimally invasive direct coronary artery bypass (MIDCAB) is an alternative for revascularisation of the isolated left anterior descending (LAD) artery or as a multi-vessel (MV) procedure for the diagonal branch (RD) or the left circumflex coronary artery (LCX) region. Methods: From 2021 to 2022, 91 patients underwent MIDCAB or multi-vessel MIDCAB procedures in our heart center. The left internal mammary artery (LIMA) was anastomosed to the left anterior descending artery via the left minithoracotomy approach in all patients. Results: Of the patients, a total of 86.8% were male. Eighty percent of the patients had two- or three-vessel coronary artery disease. The mean age was 65.1 ± 10.1 years. The mean operation time was 2.6 ± 0.8 h. The 30-day mortality was 0. The mean required packed red blood cells (pRBC) was 0.4 ± 1.2 unit. The mean intensive care unit stay (ICU) was 1.5 ± 1.6 days. The mean follow-up time was 1.5 ± 0.5 years. One patient received percutaneous coronary intervention due to de novo stenosis of the RCA. Late mortality was 2.2%. The Kaplan-Meier survival rate was 98.8% at 1 and 2 years. Conclusions: The postoperative complication rate of our MIDCAB cohort is low, and the short-term survival is favorable. Our postoperative and short-term clinical results demonstrate that this procedure is safe and feasible.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Editorial
    暂无摘要。
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    背景:增强术后恢复(ERAS)方案旨在减少术后并发症并促进早期恢复。虽然它在非心脏手术领域已经很成熟,ERAS方法最近才在心脏手术中被采用.这篇综述的目的是评估接受心脏瓣膜手术的患者的ERAS协议的状态和实施情况,并总结相关的临床结果。方法:通过在线数据库对2015年1月和2024年1月进行文献检索。包括对接受心脏瓣膜外科手术的患者进行临床研究(随机对照试验和队列研究),并比较ERAS和常规方法。提取的数据涵盖了研究和人群特征,早期结果和每个ERAS协议的特点。结果:有14项研究符合最终搜索标准,并最终被纳入综述。总的来说,在14项研究中确定了5142名患者,ERAS组2501例,对照组2641例。七项经验仅包括接受心脏瓣膜手术的患者。十四个方案中有十二个涉及从术前到术后阶段的多种干预措施,而两项研究报告的行动仅限于术中和术后护理。我们发现,在所包含的关于针对改进和衡量结果的关键行动的协议之间存在高度异质性。所有的研究表明,ERAS途径可以安全地在心脏手术中采用,并且在大多数经验与较短的机械通气时间有关。减少术后阿片类药物的使用,减少ICU和住院时间。结论:正如非心脏手术所证明的,采用结构化ERAS方案有可能改善心脏瓣膜手术患者的结果.需要基于更大人群的进一步证据,包括更同质的途径,并报告患者满意度方面的进一步结果,术后恢复和生活质量。
    Background: Enhanced recovery after surgery (ERAS) protocols aim to reduce postoperative complications and promote earlier recovery. Although it is well established in noncardiac surgery fields, the ERAS approach has only recently been adopted in cardiac surgery. The aim of this review is to evaluate the status and implementation of ERAS protocols in patients undergoing heart valve surgery and to summarise associated clinical results. Methods: A literature search for the period January 2015 and January 2024 was performed through online databases. Clinical studies (randomised controlled trials and cohort studies) on patients undergoing heart valve surgical procedures and comparing ERAS and conventional approaches were included. The data extracted covered studies and populations characteristics, early outcomes and the features of each ERAS protocol. Results: There were 14 studies that fulfilled the final search criteria and were ultimately included in the review. Overall, 5142 patients were identified in the 14 studies, with 2501 in ERAS groups and 2641 patients who were representative of control groups. Seven experiences exclusively included patients who underwent heart valve surgery. Twelve out of fourteen protocols involved multiple interventions from the preoperative to postoperative phase, while two studies reported actions limited to intraoperative and postoperative care. We found high heterogeneity among the included protocols regarding key actions targeted for improvement and measured outcomes. All the studies showed that ERAS pathways can be safely adopted in cardiac surgery and in most of the experiences were associated with shorter mechanical ventilation time, reduced postoperative opioid use and reduced ICU and hospital stays. Conclusions: As demonstrated in noncardiac surgery, the adoption of structured ERAS protocols has the potential to improve results in patients undergoing heart valve surgery. Further evidence based on larger populations is needed, including more homogenous pathways and reporting further outcomes in terms of patient satisfaction, recovery and quality of life after surgery.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    背景:使用模拟模型进行模拟自我练习可以提高手术学员的精细运动技能和自信心。
    目的:本研究的目的是通过使用手术模拟模型来评估心胸外科学员的自我报告的信心水平。
    方法:我们对所有参与MIS模拟训练的外科医生(n=10)进行了横断面研究。所有外科医生都需要执行三个微创手术(MIS)程序(二尖瓣修复,二尖瓣置换术和主动脉瓣置换术)。根据现有的两个与自信相关的量表设计了问卷,手术自我效能感量表[SSES]和感知能力量表[PCS]。我们使用评分量表1-5评估了他们在MIS程序中使用模拟的自信心(训练前后)。计算每个域的平均得分并用作预测变量。我们还使用与每个领域相关的客观结构化技术技能评估(OSAT)开发了六个问题(PCS),并询问参与者在执行每个MICS程序后的信心。
    结果:所有评估领域的平均得分为4.7,除了“知识”(3.8)。进行了一个或多个MIS手术的外科医生得分较高(P<0.05)。执行的MIS程序的数量与自信心得分之间没有相关性。
    结论:结果表明,基于MIS模拟的心脏手术培训提高了受训者和顾问的自信心水平。尽管外科医生在接受MIS心脏手术的模拟训练后通常具有很高的自信心,与程序本身及其结果相关的技术技能仍有改进的余地。
    BACKGROUND: Simulated self-practice using simulation models could improve fine motor skills and self confidence in surgical trainees.
    OBJECTIVE: The purpose of this study is to evaluate on self-reported confidence level in cardiothoracic surgical trainees by using surgical simulation models.
    METHODS: We conducted a cross-sectional study on all surgeons (n=10) involved in MIS simulation training. All surgeons are required to perform on three minimally invasive surgery (MIS) procedures (Mitral Valve Repair, Mitral Valve Replacement and Aortic Valve Replacement). A questionnaire was designed based on two existing scales related to self-confidence, the surgical self-efficacy scale [SSES] and the perceived competency scale [PCS]. We assessed their self-confidence (before and after training) in the use of simulation in MIS procedures using rating scales 1-5. The mean score was calculated for each domain and used as the predictor variable. We also developed six questions (PCS) using Objective Structured Assessment of Technical Skills (OSAT) related to each domain and asked participants how confident they were after performing each MICS procedure.
    RESULTS: The mean score was 4.7 for all assessed domains, except \"knowledge\" (3.8). Surgeons who had performed one or more MIS procedures had higher scores (P<0.05). There was no correlation between the number of MIS procedures performed and self-confidence scores.
    CONCLUSIONS: The results indicate that the cardiac surgery training based on MIS simulation improves trainees and consultants in terms of the level of self-confidence. Although surgeons generally have high levels of self-confidence after simulation training in MIS cardiac procedures, there is still room for improvement with respect to technical skills related to the procedure itself and its results.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Case Reports
    锯齿肌肋间后平面阻滞(SPSIPB)是一种新型的椎旁阻滞。它提供了前外侧后胸壁镇痛。这是一个干扰平面块,在超声引导下进行,地标的可视化很容易。它在第三肋骨水平的锯齿后上肌深处进行。直到现在,有关于使用单发SPSIPB的案例报告,但是没有关于使用SPSIPB阻滞导管技术的报道。从筋膜平面阻滞的导管连续输注对于诸如胸外科和心脏外科等疼痛手术后的术后镇痛管理很重要。因此,我们对1例接受右心房肿块切除术和微创开胸手术的患者进行了SPSIPB导管插入术.这里,在本病例报告中,我们介绍了连续SPSIPB的成功镇痛经验。
    Serratus posterior intercostal plane block (SPSIPB) is a novel periparavertebral block. It provides anterolateral posterior chest wall analgesia. It is an interfascial plane block, performed under ultrasound guidance, and the visualization of landmarks is easy. It is performed deep into the serratus posterior superior muscle at the level of the third rib. Until now, there have been case reports about the usage of single-shot SPSIPB, but there are no reports about the usage of the block catheterization technique of SPSIPB. Continuous infusion from a catheter of interfascial plane blocks is important for postoperative analgesia management after painful surgeries such as thoracic and cardiac surgeries. Thus, we performed SPSIPB catheterization in a patient who underwent right atrial mass excision with minimally invasive thoracotomy surgery. Here, we present our successful analgesic experience with continuous SPSIPB in this case report.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    主动脉瓣置换术(MIAVR)的微创方法在技术上和后勤上都要求很高。然而,由于资源有限,很少有中心开始使用具有标准设备的这些方法。我们试图报告术中和术后的临床结果,并解决MIAVR后的卫生资源利用问题。
    共有102名符合条件的主动脉瓣置换术患者参加了前瞻性研究,多中心队列研究于2015年6月至2017年12月进行。50例患者通过上倒T形半胸骨切开术(MS)接受了主动脉瓣手术,52例患者在发展中国家的两个中心使用全胸骨切开术(FS)进行手术。在所有情况下进行中央插管。主要不良心脏事件,疼痛,并对伤口并发症进行比较。进行了成本分析,并评估了插管的暴露和可行性。MS皮肤切口平均长度为5.82±0.67cm。两组的累积交叉钳夹时间不显著(91.87±34.41对94.91±33.96分钟;p=0.66)。MS表现出更短的通气时间(6.18±1.86对10.68±12.78h;p=0.029)和重症监护停留时间(33.27±19.75对49.42±47.1h;p=0.037)。主要不良心脏事件(MACE)进行比较,和MS组表现出更少的输血(1.18±0.89对1.7±0.97单位;p=0.002),肺部并发症较少(1例(2%)与2例(3.8%);p<0.001),胸骨切开术伤口感染较少(1(2%)对5(9.6%);p=0.048)。手术总死亡率为4.46%(n=5)。记录的成本显着降低有利于MS;与FS方法相比,中央插管节省了907.16美元,总成本降低了580美元(9.3%)(p<0.0001)。
    由于发展中国家缺乏物流,MIAVR不仅具有美容优势,而且显着减少了血液使用,呼吸系统并发症,疼痛,和成本。MIAVR是可行的,在发展中中心有快速的学习曲线。
    UNASSIGNED: Minimally-invasive approaches to aortic valve replacement (MIAVR) are technically and logistically demanding. However, few centers have started using these approaches with standard equipment because of the limited resources. We sought to report intra- and postoperative clinical outcomes and address health resource utilization after MIAVR.
    UNASSIGNED: A total of 102 eligible patients who had aortic valve replacement were enrolled in a prospective, multicenter cohort study conducted from June 2015 to December 2017. Fifty patients underwent aortic valve surgery via upper inverted T-shaped hemi-sternotomy (MS), and 52 patients were operated using full sternotomy (FS) in two centers in a developing country. Central cannulation was performed in all cases. Major adverse cardiac events, pain, and wound complications were compared. A cost analysis was performed, and exposure and feasibility for cannulation were assessed. The mean length of MS skin incision was 5.82 ± 0.67 cm. Cumulative cross-clamp time was insignificant between both groups (91.87 ± 34.41 versus 94.91 ± 33.96 min; p = 0.66). MS exhibited shorter ventilation time (6.18 ± 1.86 versus 10.68 ± 12.78 h; p = 0.029) and intensive care stays (33.27 ± 19.75 versus 49.42 ± 47.1 h; p = 0.037). Major adverse cardiac events (MACEs) were compared, and MS group exhibited fewer transfusions (1.18 ± 0.89 versus 1.7 ± 0.97 units; p = 0.002), fewer pulmonary complications (1 (2%) versus 2 (3.8%); p < 0.001), and less sternotomy wound infection (1 (2%) versus 5 (9.6%); p = 0.048). Total operative mortality of 4.46% was recorded (n = 5). Significant cost reduction was recorded favoring MS; central cannulation saved $907.16 and carried a total cost reduction of $580 (9.3%) when compared with the FS approach (p < 0.0001).
    UNASSIGNED: With a lack of logistics in developing countries, MIAVR not only has a cosmetic advantage but carries a significant reduction in blood use, respiratory complications, pain, and cost. MIAVR can be feasible, with a rapid learning curve in developing centers.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    背景:微创二尖瓣手术(MIC-MVS)已被确定为二尖瓣返流(MR)的首选治疗方法。但二尖瓣经导管边缘-边缘瓣膜修复术(M-TEER)通常在手术风险高的患者中进行,并且在中危患者中的应用越来越多.方法:从2010年到2021年,我们进行了723个M-TEER和123个分离的MIC-MVS程序。我们通过匹配年龄应用了敏感性分析,左心室射血分数(LVEF),EuroSCOREII和MR的病因。结果:基线特征在总体队列中显示出显着差异(p<0.01):年龄78.3岁与61.5年,EuroSCOREII5.5%与1.3%和LVEF48.4%与60.4%的M-TEER与MIC-MVS患者。M-TEER患者出院时的MR分级为中度/重度,占24.5%(171/697),与MIC-MVS中6.5%(8/123)(p<0.01)。M-TEER的一年生存率为91.5%(552/723)。MIC-MVS为97.6%(95/123)(p=0.04)。与49对(n=98)的匹配显示随访期间具有可比性的生存率,但数值上更高的平均二尖瓣梯度为4.1mmHg(95%CI:3.6-4.6)M-TEER中3.4mmHg(95%CI:3.0-3.8)(p=0.04)。结论:接受M-TEER的患者一年生存率低于MIC-MVS,但匹配后差异消失。M-TEER患者的MR减少效果较差,术后二尖瓣梯度较高。
    Background: Minimally invasive mitral valve surgery (MIC-MVS) has been established as preferred treatment of mitral regurgitation (MR), but mitral transcatheter edge-to-edge valve repair (M-TEER) is routinely performed in patients at high surgical risk and is increasingly performed in intermediate risk patients. Methods: From 2010 to 2021, we performed 723 M-TEER and 123 isolated MIC-MVS procedures. We applied a sensitivity analysis by matching age, left ventricular ejection fraction (LVEF), EuroSCORE II and etiology of MR. Results: Baseline characteristics showed significant differences in the overall cohort (p < 0.01): age 78.3 years vs. 61.5 years, EuroSCORE II 5.5% vs. 1.3% and LVEF 48.4% vs. 60.4% in M-TEER vs. MIC-MVS patients. Grade of MR at discharge was moderate/severe in 24.5% (171/697) in M-TEER vs. 6.5% (8/123) in MIC-MVS (p < 0.01). One-year survival was 91.5% (552/723) in M-TEER vs. 97.6% (95/123) in MIC-MVS (p = 0.04). A matching with 49 pairs (n = 98) showed comparable survival during follow-up, but a numerically higher mean mitral valve gradient of 4.1 mmHg (95% CI: 3.6-4.6) vs. 3.4 mmHg (95% CI: 3.0-3.8) in M-TEER (p = 0.04). Conclusions: Patients undergoing M-TEER had lower one-year survival than MIC-MVS, but differences disappeared after matching. Reduction in MR was less effective in M-TEER patients and postprocedural mitral valve gradients were higher.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

公众号