solids

  • 文章类型: Journal Article
    背景:使用单次推注一致性进行吞咽的客观评估在言语-语言病理学家(SLP)中很受欢迎,但对其他推注一致性的推广有限。饮食吞咽能力(SPEAD)测试使用三种不同的一致性评估吞咽的口腔和咽部阶段。
    目的:本研究的目的是在20-79岁的健康个体中建立SPEAD测试的规范数据。
    方法:从社区招募的112名健康成年人分为三个年龄组(20-39.11岁、40-59.11岁和60-79.11岁)。参与者吞下100克的水和增厚的电子,和6.67gParleMonaco的视频记录用于数据分析。
    结果:CronbachsAlpha测试表明内部一致性良好,类别间相关性测试显示,所有SPEAD参数的评分者间可靠性都很高。老年人表现出更多的咬伤,咀嚼,还有燕子,与年轻人和中年人相比,需要更多的吞咽时间。同样,老年人的摄食速度和SPEAD率最低。SPEAD指数在三个一致性之间也显示出显著差异,p<0.01。
    结论:总之,SPEAD测试被认为是可行的,可靠,在印度20至79岁的健康成年人中有效。本研究中建立的基于年龄和性别的规范数据将使SLP能够使用一种测试来评估口腔和咽部阶段中不同一致性的吞咽困难的存在和/或不存在。
    BACKGROUND: Objective evaluation of swallowing using single bolus consistency are popular among Speech-Language Pathologists (SLPs) but has limited generalization to other bolus consistencies. The Swallowing Proficiency for Eating and Drinking (SPEAD) test assesses the oral and pharyngeal phases of swallowing using three different consistencies.
    OBJECTIVE: The aim of this study was to establish normative data for the SPEAD test among healthy individuals aged 20-79 years.
    METHODS: One hundred and twelve healthy adults recruited from the community were divided into three age groups (20-39.11, 40-59.11, & 60-79.11 years). Participants swallowing 100 g of water and thickened Electral, and 6.67 g of Parle Monaco was video recorded for data analysis.
    RESULTS: Cronbachs Alpha test indicated good to excellent internal consistency and inter-class correlation test revealed a high level of inter-rater reliability for all SPEAD parameters. Older adults exhibited a higher number of bites, chews, and swallows, and required more time to swallow compared to younger and middle adults. Similarly, speed of ingestion and SPEAD rate were lowest in older adults. SPEAD indices also showed significant differences across the three consistencies at p < 0.01.
    CONCLUSIONS: In summary, the SPEAD test was found to be feasible, reliable, and valid in healthy adults of India between 20 and 79 years of age. The age and sex based normative data established in this study will enable SLPs in assessing the presence and / or absence of swallowing difficulties in the oral and pharyngeal phases across different consistencies using one test.
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  • 文章类型: Journal Article
    背景:针对国际研究表明,早期引入常见食物过敏原可以减少发生过敏的机会,2016年,澳大利亚临床免疫学和过敏协会(ASCIA)修订了过敏原介绍指南,建议在婴儿第一年早期引入过敏原。澳大利亚的食物过敏率很高,对遵守过敏原引入指南的理解有限,尤其是在农村地区。该项目探讨了农村父母对ASCIA指南的遵守情况。
    方法:这是一项混合方法的横断面研究,使用在线调查,包括多项选择和定性的简短回答。样本是来自新南威尔士州两个农村卫生区的336名妇女。都是18岁或以上,自2018年7月以来怀孕或分娩。描述性统计数据用于衡量行为与推荐指南的一致性,主题分析用于分析态度和解释。
    结果:在84.3%的儿童中,喂养遵守了所有研究的四项指导方针,包括在怀孕期间不消除过敏原(98%),固体引入年龄(97.7%),在引入固体期间继续母乳/牛奶配方(95%),和引入过敏原的年龄(92.9%)。依从性与受教育程度无显著相关(X2=17.9,P=.056),既往过敏史[母亲(X2=0.945,P=.623)和既往儿童(X2=0.401,P=.818)],或怀孕期间接受的初级保健。超过90%的参与者同意或强烈同意准则是现实的,值得信赖,对孩子的健康很重要。然而,主题分析显示,父母对孩子个人进步的看法,以及医疗状况或其他情况,例如母乳喂养的挑战,通常优先于遵守特定的指南建议。
    结论:此处发现的ASCIA指南的高依从率与大城市研究的结果相当,对未来的人群健康也是令人鼓舞的。参与者对指南的评论意味着农村决策者对父母关于婴儿喂养的决定有多种影响,通常包括父母自己的直觉和经验。进一步研究,以提高对信息作用的理解,看护者,以及其他有关喂养态度和行为的父母决策的影响将是必要的,以优化农村地区的依从性。
    Responding to international research showing that early introduction of common food allergens can reduce the chance of developing allergies, in 2016 the Australasian Society of Clinical Immunology and Allergy (ASCIA) revised allergen introduction guidelines, recommending earlier introduction of allergens to infants in their first year. Australia has high food allergy rates, and limited understanding of adherence to allergen introduction guidelines, especially in rural areas. This project explored rural parent adherence to ASCIA guidelines.
    This was a mixed method cross sectional study using an online survey including multiple-choice and qualitative short answer responses. The sample were 336 women from two rural health districts in New South Wales. All were aged 18 or over, and either pregnant or had delivered a baby since July 2018. Descriptive statistics were used to measure behavioural alignment with the recommended guidelines, thematic analysis was used to analyse attitudes and explanations.
    In 84.3% of children, feeding adhered to all four guidelines studied, including no elimination of allergens during pregnancy (98%), age of introduction of solids (97.7%), continuation of breast milk/cow\'s milk formula during introduction of solids (95%), and age of introduction of allergens (92.9%). Adherence was not significantly correlated with the education (X2 = 17.9, P = .056), prior history of allergy [neither mother (X2 = 0.945,P = .623) nor previous children (X2 = 0.401,P = .818)], or primary care received during pregnancy. More than 90% of participants agreed or strongly agreed that the guidelines are realistic, trustworthy, and important for the health of their child. However, thematic analysis revealed that parents\' perceptions of a child\'s individual progress, and medical conditions or other circumstances, such as challenges with breastfeeding, will often take precedence over adherence to specific guideline recommendations.
    High rates of adherence with ASCIA guidelines found here are comparable with findings from metropolitan studies and encouraging for future population health. Participant comments on the guidelines imply to rural policymakers that there are multiple influences on parent decisions about infant feeding, often including parents\' own intuition and experiences. Further studies to improve understanding of the role of information, carers, and other influences on parent decision-making concerning feeding attitudes and behaviours will be necessary to optimise adherence in rural areas.
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  • 文章类型: Journal Article
    富营养化是水体中藻类的过度生长,导致生物多样性丧失,降低水质和对人的吸引力。这是水体中的一个重要问题。在本文中,我们提出了一种低成本传感器,用于监测浓度在0至200mg/L之间以及沉积物和藻类的不同混合物(0、20、40、60、80和100%藻类,其余为沉积物)。我们使用两个光源(红外和RGBLED)和两个光源90°和180°的光感受器。该系统具有微控制器(M5stacks),该微控制器为光源供电并获得由光感受器接收的信号。此外,微控制器负责发送信息和生成警报。我们的结果表明,使用90°红外光可以确定浊度,NTU读数高于2.73NTU的误差为7.45%,用180°红外光可以测量固体浓度,误差为11.40%。根据藻类百分比的测定,使用神经网络的分类精度为89.3%,水中藻类mg/L的测定误差为17.95%。
    Eutrophication is the excessive growth of algae in water bodies that causes biodiversity loss, reducing water quality and attractiveness to people. This is an important problem in water bodies. In this paper, we propose a low-cost sensor to monitor eutrophication in concentrations between 0 to 200 mg/L and in different mixtures of sediment and algae (0, 20, 40, 60, 80, and 100% algae, the rest are sediment). We use two light sources (infrared and RGB LED) and two photoreceptors at 90° and 180° of the light sources. The system has a microcontroller (M5stacks) that powers the light sources and obtains the signal received by the photoreceptors. In addition, the microcontroller is responsible for sending information and generating alerts. Our results show that the use of infrared light at 90° can determine the turbidity with an error of 7.45% in NTU readings higher than 2.73 NTUs, and the use of infrared light at 180° can measure the solid concentration with an error of 11.40%. According to the determination of the % of algae, the use of a neural network has a precision of 89.3% in the classification, and the determination of the mg/L of algae in water has an error of 17.95%.
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  • 文章类型: Journal Article
    雨水池广泛用于通过沉积颗粒和相关污染物来控制径流质量。它们的维护需要定期清除和处理积聚的材料。这就需要对物质危险性进行评估,包括金属污染造成的潜在危险。在这里,我们使用几种化学分析方法(总提取,顺序提取,薄膜DGT中的扩散梯度,和孔隙水提取),以考虑不同方法的互补性和可比性。在可能测量相似金属分数(DGT和顺序提取的分数1(吸附的和可交换的金属和碳酸盐)或孔隙水浓度)的分析之间没有发现明确的关系。烧失量(LOI)与本文开发的包含不同金属的环境风险指标(∑等级)有显著正相关,物种,和环境终点。观察到池塘之间的金属含量差异很大。由于聚类在不同的分析之间受到限制,仍然需要对不同参数进行综合分析,以充分了解金属形态和生物利用度。
    Stormwater ponds are widely used for controlling runoff quality through the sedimentation of particles and associated pollutants. Their maintenance requires regular removal and disposal of accumulated material. This necessitates an assessment of material hazardousness, including potential hazard due to its contamination by metals. Here we analyze 32 stormwater pond sediment samples from 17 facilities using several chemical analysis methods (total extraction, sequential extraction, diffusive gradients in thin-films DGT, and pore water extraction) in order to consider the complementarity and comparability of the different approaches. No clear relationship was found between analyses that have the potential to measure similar metal fractions (DGT and either fraction 1 of the sequential extraction (adsorbed and exchangeable metals and carbonates) or pore water concentrations). Loss on ignition (LOI) had a significant positive correlation with an indicator of the environmental risk developed in this paper (∑ranks) that incorporates different metals, speciations, and environmental endpoints. Large variations in metal levels were observed between ponds. As clustering was limited between the different analyses, a comprehensive analysis of different parameters is still needed to fully understand metal speciation and bioavailability.
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  • 文章类型: Journal Article
    分子固体中高度精确的化学位移预测是NMR晶体学成功和快速发展的背后。然而,有时会报告预测的氢和碳化学位移的异常大的误差。了解这些偏差对于NMR晶体学的可靠性至关重要。这里,最近报道的预测氢和碳化学位移的大偏差的一系列固体吡啶富马酸盐被彻底分析。研究了几何优化协议和NMR计算的计算水平对预测化学位移准确性的影响。使用GGA进行定期计算,采用meta-GGA和杂化功能。此外,计算了耦合簇单双(CCSD)水平的分子校正。还研究了核离域对结构和NMR屏蔽的影响。具有计算要求高的混合功能的几何优化导致质子化学位移预测的实质性改善。
    Highly accurate chemical-shift predictions in molecular solids are behind the success and rapid development of NMR crystallography. However, unusually large errors of predicted hydrogen and carbon chemical shifts are sometimes reported. An understanding of these deviations is crucial for the reliability of NMR crystallography. Here, recently reported large deviations of predicted hydrogen and carbon chemical shifts of a series of solid pyridinium fumarates are thoroughly analyzed. The influence of the geometry optimization protocol and of the computational level of NMR calculations on the accuracy of predicted chemical shifts is investigated. Periodic calculations with GGA, meta-GGA and hybrid functionals are employed. Furthermore, molecular corrections at the coupled-cluster singles-and-doubles (CCSD) level are calculated. The effect of nuclear delocalization on the structure and NMR shielding is also investigated. The geometry optimization with a computationally demanding hybrid functional leads to a substantial improvement in proton chemical-shift predictions.
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  • 文章类型: Journal Article
    含油污泥在石油开采过程中广泛产生,storage,交通运输,和精炼,并且在老化过程中变得更加稳定。老化含油污泥的界面稳定性阻碍了石油资源的回收和处置。本文综述了老化含油污泥的界面膜稳定性,这是通过在重质组分(沥青质和树脂)和无机颗粒之间形成粘弹性和刚性双层界面膜而发生的。双层界面膜增强了界面膜强度,阻碍了液滴的聚集,有助于形成稳定和高粘度的油-水-固体三相混合物。最近用于降低界面膜稳定性的破乳技术分类如下:去除重质组分,改变沥青质骨料结构,降低无机颗粒含量。通过深入分析沥青质和树脂的微观结构和界面性质,有望开发出更有效的破乳技术。以及全面研究各种成分之间复杂的相互作用。这篇综述在稳定机制和相应的失稳方法之间架起了桥梁,这将促进未来老化含油污泥处理的研究。
    Oily sludge is widely produced in the processes of petroleum exploitation, storage, transportation, and refining, and becomes more stable during aging. The interfacial stability of aging oily sludge hinders the recovery and disposal of oil resources. This review summarizes the interfacial film stability of aging oily sludge, which occurs through the formation of viscoelastic and rigid bilayer interfacial films between heavy components (asphaltenes and resins) and inorganic particles. The bilayer interfacial films enhance interfacial film strength and hinder the aggregation of droplets, contributing to the formation of a stable and high-viscosity oil-water-solid three-phase mixture. Recent demulsification technologies for reducing the stability of interfacial films have been classified as follows: removing heavy components, changing asphaltene aggregate structure, and reducing inorganic particle content. More efficient demulsification technologies are expected to be developed by deeply analyzing the microstructure and interfacial properties of asphaltenes and resins, as well as comprehensively studying the complex interactions among various components. This review constructs a bridge between the stability mechanism and the corresponding destabilization methods, which would promote future studies in aging oily sludge treatment.
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  • 文章类型: Journal Article
    It is shown that meeting the increased nutritional demand of preterm infants from birth is not only important for survival but essentially contributes to the infants` overall development and long-term health. While there are established guidelines for weaning term infants, evidence regarding preterm infants is scarce and less precise. The aim of this study was to identify the current practices on introducing solids to preterm infants amongst caregivers in Salzburg and determine potential reasons for early weaning.
    Altogether 68 infants born between 24 0/7 and 36 6/7 weeks were recruited and detailed structured interviews with the caregivers were conducted at 17 weeks corrected age. Weight, height and head circumference were collected.
    52% of the study group received solids before the recommended 17 weeks corrected age. For this group the mean age being 13.77 ± 1.11 weeks corrected age. Premature introduction of solids significantly correlates with exclusively and early formula-feeding. 34% were weaned due to recommendation by their paediatrician. 23% of the preterm infants even received solids before 12 weeks corrected age, putting them at risks for developing obesity, celiac disease and diabetes.
    This study shows the necessity for clear guidelines regarding the introduction of complementary feeding in preterm infants as well as the importance of their implementation. Caregivers should receive information on this topic early enough and they should fully understand the difference between chronological and corrected age.
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  • 文章类型: Journal Article
    以Poynting-Thomson-Zener流变模型为例,同时表现出耗散和波传播,具有非线性色散关系,我们引入并研究了有限差分数值格式。我们的目标是证明其特性,并在以后的连续热力学问题应用中简化计算。关键要素是以相对于彼此的半个空间和时间步长偏移的离散量的定位。根据数量和控制它们的方程式的时空属性来选择排列。数值稳定性,耗散误差,并详细分析了色散误差。找到了最好的设置,该方案能够做出精确和快速的预测。最后,将所提出的方案与商业有限元软件进行比较,COMSOL,即使在最简单的弹性建模水平上,也证明了本质区别。
    On the example of the Poynting-Thomson-Zener rheological model for solids, which exhibits both dissipation and wave propagation, with nonlinear dispersion relation, we introduce and investigate a finite difference numerical scheme. Our goal is to demonstrate its properties and to ease the computations in later applications for continuum thermodynamical problems. The key element is the positioning of the discretized quantities with shifts by half space and time steps with respect to each other. The arrangement is chosen according to the spacetime properties of the quantities and of the equations governing them. Numerical stability, dissipative error, and dispersive error are analyzed in detail. With the best settings found, the scheme is capable of making precise and fast predictions. Finally, the proposed scheme is compared to a commercial finite element software, COMSOL, which demonstrates essential differences even on the simplest-elastic-level of modeling.
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  • 文章类型: Journal Article
    The recent results attained from a thermodynamically conceived numerical scheme applied on wave propagation in viscoelastic/rheological solids are generalized here, both in the sense that the scheme is extended to four spacetime dimensions and in the aspect of the virtues of a thermodynamical approach. Regarding the scheme, the arrangement of which quantity is represented where in discretized spacetime, including the question of appropriately realizing the boundary conditions, is nontrivial. In parallel, placing the problem in the thermodynamical framework proves to be beneficial in regards to monitoring and controlling numerical artefacts-instability, dissipation error, and dispersion error. This, in addition to the observed preciseness, speed, and resource-friendliness, makes the thermodynamically extended symplectic approach that is presented here advantageous above commercial finite element software solutions.
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  • 文章类型: Journal Article
    在缺乏预防COVID-19的有效疫苗的情况下,重要的是能够跟踪社区感染,为旨在减少传播的公共卫生干预措施提供信息,从而减轻对医疗保健的压力,改善健康结果,减少经济不确定性。废水监测已迅速成为通过测量废水系统中RNA信号趋势来有效监测社区感染的潜在工具。在这项研究中,SARS-CoV-2病毒RNAN1和N2基因区域在两个为加拿大国家首都地区服务的水资源回收设施(WRRF)中从进水后砂砾固体(PGS)和初级澄清污泥(PCS)中收集的固体中进行了定量。即,渥太华市,开(弹出。≈1.1M)和加蒂诺市,QC(流行。≈280K)。与RT-qPCR相比,PCS样品使用RT-ddPCR显示信号抑制,与PGS样品显示相似的可量化的RNA浓度使用两种测定。RT-qPCR显示PCS中N1和N2基因区的检测频率较高(92.7,90.6%,n=6)与PGS样本(79.2,82.3%,n=5)。因此,PCS采样可能是SARS-CoV-2病毒定量的有效方法,特别是在社区COVID-19发病率下降和低的时期。对于两个WRRF,在三个月的时间内,确定辣椒轻度斑驳病毒(PMMoV)在PCS中的RNA信号变化较小,无论环境条件如何,与拟杆菌16SrRNA或人类18SrRNA相比,使PMMoV成为SARS-CoV-2信号归一化的潜在有用生物标志物。来自两个城市WRRF的PMMoV归一化PCSRNA信号与区域公共卫生流行病学指标相关,将PCS标准化为粪便指标(PMMoV),作为监测社区SARS-Cov-2感染减少和低发生率期间趋势的潜在有效工具。
    In the absence of an effective vaccine to prevent COVID-19 it is important to be able to track community infections to inform public health interventions aimed at reducing the spread and therefore reduce pressures on health-care, improve health outcomes and reduce economic uncertainty. Wastewater surveillance has rapidly emerged as a potential tool to effectively monitor community infections through measuring trends of RNA signal in wastewater systems. In this study SARS-CoV-2 viral RNA N1 and N2 gene regions are quantified in solids collected from influent post grit solids (PGS) and primary clarified sludge (PCS) in two water resource recovery facilities (WRRF) serving Canada\'s national capital region, i.e., the City of Ottawa, ON (pop. ≈ 1.1M) and the City of Gatineau, QC (pop. ≈ 280K). PCS samples show signal inhibition using RT-ddPCR compared to RT-qPCR, with PGS samples showing similar quantifiable concentrations of RNA using both assays. RT-qPCR shows higher frequency of detection of N1 and N2 gene regions in PCS (92.7, 90.6%, n = 6) as compared to PGS samples (79.2, 82.3%, n = 5). Sampling of PCS may therefore be an effective approach for SARS-CoV-2 viral quantification, especially during periods of declining and low COVID-19 incidence in the community. The pepper mild mottle virus (PMMoV) is determined to have a less variable RNA signal in PCS over a three month period for two WRRFs, regardless of environmental conditions, compared to Bacteroides 16S rRNA or human 18S rRNA, making PMMoV a potentially useful biomarker for normalization of SARS-CoV-2 signal. PMMoV-normalized PCS RNA signal from WRRFs of two cities correlated with the regional public health epidemiological metrics, identifying PCS normalized to a fecal indicator (PMMoV) as a potentially effective tool for monitoring trends during decreasing and low-incidence of infection of SARS-Cov-2 in communities.
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