rectal prolapse

直肠脱垂
  • 文章类型: Journal Article
    背景:腹腔镜直肠切除术是全层直肠脱垂的既定治疗选择。最近,缩孔手术(RPS)已经成为一个新的概念,与传统的多端口手术(MPS)相比,减少了术后疼痛并改善了美容效果。本研究旨在评估RPS治疗全层直肠脱垂的可行性和安全性。
    方法:2012年10月至2018年12月,37例患者(MPS:10例,RPS:27例)接受腹腔镜直肠切除术治疗全层直肠脱垂。腹腔镜后网状直肠固定术(Wells程序)是我们医院全层直肠脱垂的标准技术。使用多信道接入设备执行RPS,一个额外的12毫米右手端口。回顾性比较MPS和RPS的短期结果。
    结果:在中位手术时间上,MPS和RPS之间没有观察到显着差异,中位失血量,术后并发症发生率,和手术后住院时间中位数。
    结论:减孔腹腔镜后网眼直肠固定术可作为全层直肠脱垂的有效治疗选择。然而,为了确立RPS优于MPS的优势,一个潜在的,随机化,有必要进行对照试验。
    BACKGROUND: Laparoscopic rectopexy is an established treatment option for full-thickness rectal prolapse. Recently, reduced port surgery (RPS) has emerged as a novel concept, offering reduced postoperative pain and improved cosmetic outcomes compared with conventional multiport surgery (MPS). This study aimed to evaluate the feasibility and safety of RPS for full-thickness rectal prolapse.
    METHODS: From October 2012 to December 2018, 37 patients (MPS: 10 cases, RPS: 27 cases) underwent laparoscopic rectopexy for full-thickness rectal prolapse. Laparoscopic posterior mesh rectopexy (Wells procedure) is the standard technique for full-thickness rectal prolapse at our hospital. RPS was performed using a multi-channel access device, with an additional 12-mm right-hand port. Short-term outcomes were retrospectively compared between MPS and RPS.
    RESULTS: No significant differences were observed between MPS and RPS in the median operative time, the median blood loss volume, the postoperative complication rates, and median hospital stay duration after surgery.
    CONCLUSIONS: Reduced port laparoscopic posterior mesh rectopexy may serve as an effective therapeutic option for full-thickness rectal prolapse. However, to establish the superiority of RPS over MPS, a prospective, randomized, controlled trial is warranted.
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  • 文章类型: Case Reports
    直肠脱垂是一种相对罕见的疾病,直肠粘膜从肛管中突出。诊断是通过体检和临床评估,和手术治疗方案可能有所不同。文献中很少描述伪装成直肠脱垂的肛门息肉。一名79岁的男子有四年的膨胀史,肛门突出的肿块,排便和排便加剧。他最初被诊断为直肠脱垂,并通过机器人进行了乙状结肠切除术。手术后不久,他的症状复发了,他被转介给另一位外科医生进行重新评估。一个大的,体格检查可见息肉脱垂。进行了结肠镜检查和肛门镜检查。CT腹部/骨盆显示直肠内有肿块,活检显示腺瘤性息肉伴高度发育不良。患者接受了直肠息肉的经肛门切除术,症状永久缓解。为了准确的诊断,对患者的病史进行全面评估是至关重要的,体检,和不寻常的直肠脱垂的临床过程。大的稀有,息肉脱垂,以及它们与其他肛门直肠疾病相似的表现,可能有助于该患者诊断为直肠脱垂和随后的乙状结肠直肠切除术代替经肛门切除息肉。体格检查时触诊茎应该会引起息肉的怀疑,和进一步的工作,例如结肠镜检查和/或肛门镜检查,应该进行确认诊断。
    Rectal prolapse is a relatively rare condition where the rectal mucosa protrudes out of the anal canal. The diagnosis is made through a physical exam and clinical evaluation, and surgical treatment options can vary. Anal polyps masquerading as rectal prolapse have rarely been described in the literature. A 79-year-old man presented with a four-year history of a bulging, protruding mass from his anus that is exacerbated with defecation and bowel movements. He was initially diagnosed with rectal prolapse and had a proctosigmoidectomy performed robotically. Shortly after the procedure, his symptoms recurred, and he was referred to a different surgeon for reevaluation. A large, prolapsed polyp was visible on the physical exam. A colonoscopy and an anoscopy were performed. The CT abdomen/pelvis revealed a mass within the rectum, and the biopsy showed an adenomatous polyp with high-grade dysplasia. The patient underwent a transanal excision of the rectal polyp, with symptoms permanently resolving. For an accurate diagnosis, it is crucial to conduct a comprehensive assessment of the patient\'s history, a physical exam, and an unusual clinical course of rectal prolapse. The rarity of large, prolapsed polyps, along with their similar presentation to that of other anorectal conditions, may have contributed to this patient\'s diagnosis of rectal prolapse and the subsequent proctosigmoidectomy in place of a transanal excision of a polyp. The palpation of a stalk on a physical exam should raise suspicion of a polyp, and further workup, such as a colonoscopy and/or anoscopy, should be conducted to confirm the diagnosis.
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  • 文章类型: Journal Article
    本研究旨在研究纯种和杂交牧群母猪盆腔器官脱垂的遗传参数。在32个纯种和8个杂交农场的单个母猪水平上,盆腔器官脱垂被记录为正常或脱垂。总的来说,在2018年至2023年之间,记录了75,162头来自单一母系的纯种长白猪,而在2020年至2023年之间,有18,988头商业双向杂交(长白猪x大白)母猪。家系中有5,122,005只动物。在模型中,纯种和杂种的脱垂被认为是两个不同的性状。杂交母猪的系谱是根据基因型通过亲子关系确定的。纯种和杂种的平均发病率分别为1.81%和3.93%,分别。双变量模型结合了平差组和区域的固定效应以及当代群体的随机效应(第一个平差的农场和交配年份和月份),加性遗传,和残余。遗传参数估计是使用BLUPF90+和AIREML选项获得的。杂种的估计累加方差大于纯种。在观察到的尺度上,纯种的遗传力估计为0.09(0.006),杂种的遗传力估计为0.11(0.014),使用线性模型的遗传相关性为0.83。结果表明,包括发病率较高的杂交母猪的数据是有益的,选择减少纯种母猪群脱垂的发生率也将有利于商业杂交母猪群。
    This study aimed to investigate genetic parameters for sow pelvic organ prolapse in purebred and crossbred herds. Pelvic organ prolapse was recorded as normal or prolapsed on the individual sow level across 32 purebred and 8 crossbred farms. In total, 75,162 purebred Landrace sows from a single maternal line were recorded between 2018 and 2023, while 18,988 commercial two-way crossbred (Landrace x Large White) sows were available between 2020 and 2023. There were 5,122,005 animals included in the pedigree. The prolapse in purebreds and crossbreds was considered two different traits in the model. Pedigrees of the crossbred sows were determined based on genotypes through parentage assignment. The average incidence rates were 1.81% and 3.93% for purebreds and crossbreds, respectively. The bivariate model incorporated fixed effects of parity group and region with random effects of contemporary group (farm and mating year and month at the first parity), additive genetic, and residual. Genetic parameter estimates were obtained using BLUPF90+ with the AIREML option. The estimated additive variance was larger in crossbreds than in purebreds. Estimates of heritability in the observed scale were 0.09 (0.006) for purebreds and 0.11 (0.014) for crossbreds, with a genetic correlation of 0.83 using a linear model. Results suggested that including data from crossbreds with higher incidence rate is beneficial and selection to reduce the prolapse incidence in purebred sow herds would also benefit commercial crossbred sow herds.
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  • 文章类型: Journal Article
    虽然在成年人口中更常见,直肠脱垂是一种常见的肛门直肠疾病,可发生在儿童和青少年。虽然许多病例无需干预即可自发解决,较新的微创手术和手术的出现为儿科患者提供了选择.这里,我们回顾了病理生理学,病因学,介绍,在过去的几十年中,儿科人群直肠脱垂的诊断和治疗原则已经发展。
    这些文献是从免费数据库中查询的,这些数据库可供公众使用,包括美国国立卫生研究院国家医学图书馆MEDLINE和PubMed,以获取1975年1月1日至2023年12月1日出版的手稿。没有随附英语翻译的手稿或完全用外语编写的手稿被排除在外。
    许多情况导致儿童直肠脱垂,包括便秘,胃肠道感染性和非感染性病因,囊性纤维化,营养不良,神经性,解剖,领先点,和虐待。直肠脱垂的初始管理是医学管理,解决与直肠脱垂相关的潜在疾病,并尝试手动复位。对于复发性直肠脱垂的患者,除了通过开放和较新的微创方法进行手术直肠固定术外,还提供了多种非侵入性和程序性管理选择,包括注射硬化疗法和肛门包围。
    尽管评估取得了重大进展,在过去的几十年中,儿科肛肠疾病的程序和手术管理,在儿童和青少年直肠脱垂的治疗中,临床医生和外科医生的实践仍然存在很大差异。未来仍有许多研究要改善该患者群体的临床结果。
    UNASSIGNED: Although more frequent in the adult population, rectal prolapse is a common anorectal condition that can occur in children and adolescents. While many cases spontaneously resolve without the need for intervention, the advent of newer minimally invasive procedures and operations have provided options for pediatric patients. Here, we review the pathophysiology, etiology, presentation, diagnosis and principles of management of rectal prolapse in the pediatric population as it has evolved over the past several decades.
    UNASSIGNED: The literature was queried from free databases available to the public including the National Institute of Health National Library of Medicine MEDLINE and PubMed for manuscripts published from January 1, 1975 to December 1, 2023. Manuscripts without an accompanying English translation or those written entirely in foreign languages were excluded.
    UNASSIGNED: Numerous conditions contribute to rectal prolapse in children, including constipation, gastrointestinal infectious and non-infectious etiologies, cystic fibrosis, malnutrition, neurogenic, anatomic, lead points, and abuse. Initial management of rectal prolapse is medical management, addressing the underlying condition associated with rectal prolapse along with attempted manual reduction. For patients with recurrent rectal prolapse, a variety of noninvasive and procedural management options are available including injection sclerotherapy and anal encirclement in addition to surgical rectopexy by open and newer minimally invasive methods.
    UNASSIGNED: Despite significant advances in the evaluation, procedural and surgical management of pediatric anorectal conditions in the last few decades, there continues to be substantial variation in clinicians\' and surgeons\' practice for the treatment of rectal prolapse in children and adolescents. Much remains to be studied in the future to improve clinical outcomes for this patient population.
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  • 文章类型: Journal Article
    背景:会阴直肠切除术是一项复杂的手术,需要高级技能。目前,在此过程中没有用于训练的模拟器。作为我们开发虚拟现实模拟器目标的一部分,我们的目标是开发和验证特定任务的指标,以评估该程序的性能.我们进行了一项分三个阶段的研究,以建立特定任务的指标,就制定的指标的适当性获得专家共识,并建立所开发指标的判别效度。
    方法:在第一阶段,我们利用层次任务分析来制定指标。在第二阶段,一项涉及结直肠外科专家的调查确定了所制定指标的重要性.第三阶段旨在为新手(PGY1-3)和专家(PGY4-5和教职员工)建立判别效度。他们在直肠脱垂模型上进行了会阴直肠切除术。视频记录由两名评估者使用该程序的全球评级和任务特定指标进行独立评估。使用Kruskal-Wallis检验计算和分析两个指标的总分。使用具有Benjamini-Hochberg校正的Mann-WhitneyU检验来评估组间差异。计算Spearman的等级相关系数以评估全局和任务特定分数之间的相关性。
    结果:在第二阶段,共招募23名结直肠外科医生,并就所有任务特异性指标达成共识.在第三阶段,参与者(n=22)包括新手(n=15)和专家(n=7).总体得分和特定任务得分之间存在很强的正相关性(rs=0.86;P<0.001)。在总体评分(χ2=15.38;P<0.001;df=2)和任务特异性评分(χ2=11.38;P=0.003;df=2)方面均检测到显著的组间差异。
    结论:使用生物组织直肠脱垂模型,这项研究记录了较高的IRR和显著的判别有效性证据,以支持使用任务特定指标的基于视频的评估.
    BACKGROUND: Perineal proctectomy is a complex procedure that requires advanced skills. Currently, there are no simulators for training in this procedure. As part of our objective of developing a virtual reality simulator, our goal was to develop and validate task-specific metrics for the assessment of performance for this procedure. We conducted a three-phase study to establish task-specific metrics, obtain expert consensus on the appropriateness of the developed metrics, and establish the discriminant validity of the developed metrics.
    METHODS: In phase I, we utilized hierarchical task analysis to formulate the metrics. In phase II, a survey involving expert colorectal surgeons determined the significance of the developed metrics. Phase III was aimed at establishing the discriminant validity for novices (PGY1-3) and experts (PGY4-5 and faculty). They performed a perineal proctectomy on a rectal prolapse model. Video recordings were independently assessed by two raters using global ratings and task-specific metrics for the procedure. Total scores for both metrics were computed and analyzed using the Kruskal-Wallis test. A Mann-Whitney U test with Benjamini-Hochberg correction was used to evaluate between-group differences. Spearman\'s rank correlation coefficient was computed to assess the correlation between global and task-specific scores.
    RESULTS: In phase II, a total of 23 colorectal surgeons were recruited and consensus was obtained on all the task-specific metrics. In phase III, participants (n = 22) included novices (n = 15) and experts (n = 7). There was a strong positive correlation between the global and task-specific scores (rs = 0.86; P < 0.001). Significant between-group differences were detected for both global (χ2 = 15.38; P < 0.001; df = 2) and task-specific (χ2 = 11.38; P = 0.003; df = 2) scores.
    CONCLUSIONS: Using a biotissue rectal prolapse model, this study documented high IRR and significant discriminant validity evidence in support of video-based assessment using task-specific metrics.
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  • 文章类型: Case Reports
    直肠脱垂,以直肠粘膜或全层组织通过肛管突出为特征,显著影响生活质量,诊断后需要及时干预。此病例报告介绍了我们机构收治的两例直肠脱垂的治疗方法,这些病例均患有肛门脱垂性肿块和许多相关的合并症,以及随后使用Thiersch程序进行的手术治疗。按照程序,两名患者均在术后接受监测,一旦绝对稳定,并定期跟进。手术是直肠脱垂的主要治疗方法,虽然各种手术技术解决直肠脱垂,诸如Thiersch程序之类的肛门包围程序已被较新的腹部或会阴方法所取代。然而,对于选定的患者人群,这是一个有价值的选择。Thiersch手术是治疗直肠脱垂高危患者或依从性较差的患者进行更广泛手术的理想方式。它也可以暂时使用,直到将来计划进一步的明确治疗。
    Rectal prolapse, characterized by the protrusion of rectal mucosa or full-thickness tissue through the anal canal, significantly impacts quality of life, necessitating prompt intervention upon diagnosis. This case report presents the management of rectal prolapse in two cases admitted to our institution presenting with complaints of a prolapsing anal mass and many associated comorbidities and their subsequent surgical management using the Thiersch procedure. Following the procedure, both patients were monitored postoperatively, discharged once vitally stable, and kept on regular follow-up. Surgery is the primary therapy for rectal prolapse, and while various surgical techniques address rectal prolapse, anal encirclement procedures like the Thiersch procedure have been largely replaced by newer abdominal or perineal approaches. However, it is a valuable option for select patient populations. The Thiersch procedure is an ideal modality for treating high-risk patients with rectal prolapse or those patients with poor compliance for more extensive procedures. It can also be used temporarily until a further definitive treatment is planned later in the future.
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  • 文章类型: Multicenter Study
    背景:在患有外部全层直肠脱垂(EFRP)的老年患者中,腹腔镜腹侧网孔直肠切除术(LVMR)和会阴吻合器切除术(PSR)在术后复发和功能结局方面的确切差异尚未得到研究.
    方法:我们在2012年4月至2019年4月期间对330名老年患者进行了回顾性多中心研究,分为LVMR组(n=250)和PSR组(n=80)。通过Wexner失禁量表在手术前后对患者进行评估,Altomare便秘量表,和患者满意度问卷。主要结果是EFTRP复发的发生率和危险因素。次要结果是术后尿失禁,便秘,患者满意度。
    结果:LVMR与较少的术后并发症相关(p<0.001),较低的脱垂复发(p<0.001),较低的Wexner失禁评分(p=0.03),和较低的Altomare评分(p=0.047)。此外,LVMR显示出明显较高的手术复发间隔(p<0.001),失禁改善(p=0.019),患者满意度(p<0.001)高于PSR。3例和13例患者出现LVMR和PSR的新症状,分别。脱垂复发的预测因素是LVMR(与93%的复发风险降低相关,OR0.067,95%CI0.03-0.347,p=0.001),症状持续时间(持续时间延长与复发风险增加相关,OR1.131,95%CI1.036-1.236,p=0.006),和脱垂长度(长度增加与高复发风险相关(OR=1.407,95%CI=1.197-1.655,p<0.001)。
    结论:LVMR用于低复发老年患者的EFTRP治疗是安全的,并改善术后功能结局。
    背景:临床试验.gov(NCT05915936),于2023年6月14日追溯注册。
    BACKGROUND: In elderly patients with external full-thickness rectal prolapse (EFTRP), the exact differences in postoperative recurrence and functional outcomes between laparoscopic ventral mesh rectopexy (LVMR) and perineal stapler resection (PSR) have not yet been investigated.
    METHODS: We conducted a retrospective multicenter study on 330 elderly patients divided into LVMR group (n = 250) and PSR (n = 80) from April 2012 to April 2019. Patients were evaluated before and after surgery by Wexner incontinence scale, Altomare constipation scale, and patient satisfaction questionnaire. The primary outcomes were incidence and risk factors for EFTRP recurrence. Secondary outcomes were postoperative incontinence, constipation, and patient satisfaction.
    RESULTS: LVMR was associated with fewer postoperative complications (p < 0.001), lower prolapse recurrence (p < 0.001), lower Wexner incontinence score (p = 0.03), and lower Altomare\'s score (p = 0.047). Furthermore, LVMR demonstrated a significantly higher surgery-recurrence interval (p < 0.001), incontinence improvement (p = 0.019), and patient satisfaction (p < 0.001) than PSR. Three and 13 patients developed new symptoms in LVMR and PSR, respectively. The predictors for prolapse recurrence were LVMR (associated with 93% risk reduction of recurrence, OR 0.067, 95% CI 0.03-0.347, p = 0.001), symptom duration (prolonged duration was associated with an increased risk of recurrence, OR 1.131, 95% CI 1.036-1.236, p = 0.006), and length of prolapse (increased length was associated with a high recurrence risk (OR = 1.407, 95% CI = 1.197-1.655, p < 0.001).
    CONCLUSIONS: LVMR is safe for EFTRP treatment in elderly patients with low recurrence, and improved postoperative functional outcomes.
    BACKGROUND: Clinical Trial.gov (NCT05915936), retrospectively registered on June 14, 2023.
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  • 文章类型: Case Reports
    盆腔器官脱垂(POP)是一个非常常见的问题,可以影响盆底的任何方面。通常,阴道和直肠脱垂同时发生。先前的病例报告表明,合并直肠和阴道脱垂的患者直肠脱垂的症状得到缓解;然而,整体证据是有限的。我们介绍了两名患者的病例,这些患者在合并的阴道脱垂修复后直肠脱垂的症状完全缓解。两名患者均接受了传统的直肠前突修复和腔内成形术,随后报告他们的直肠脱垂症状完全缓解,在他们六个月的术后访问中持续存在。第二名患者最终取消了先前计划的结直肠手术。也许直肠前突修补术会限制直肠活动,从而消除其脱垂或肠套叠的能力,并引起烦人的症状。我们建议那些同时患有阴道和直肠脱垂并希望进行矫正手术的人首先接受侵入性较小的阴道修复。术后对直肠脱垂症状的重新评估可能表明,更具侵入性的直肠脱垂修复,这可能涉及结肠切除术和延长住院时间,事实上并不需要。需要进一步的前瞻性和随机研究来确定首次接受阴道修复的患者合并直肠和阴道脱垂的长期结局。
    Pelvic organ prolapse (POP) is a very common problem that can affect any aspect of the pelvic floor. Often, vaginal and rectal prolapse occur simultaneously. Prior case reports have suggested resolution of symptoms of rectal prolapse in those with concomitant rectal and vaginal prolapse; however, the overall body of evidence is limited. We present the cases of two patients who had complete resolution of their symptoms of rectal prolapse after repair of a concomitant vaginal prolapse. Both patients underwent a traditional rectocele repair and perineoplasty, and subsequently reported complete resolution of their symptoms of rectal prolapse, which persisted at their six-month post-operative visits. The second patient ultimately canceled a previously scheduled rectopexy with colorectal surgery. Perhaps a rectocele repair with perineoplasty is limiting rectal mobility, and therefore eliminating its ability to prolapse or intussuscept and cause bothersome symptoms. We suggest that those with concomitant vaginal and rectal prolapse desiring corrective surgery first undergo a less invasive vaginal repair. Post-operative re-evaluation of the symptoms rectal prolapse might then demonstrate that a more invasive rectal prolapse repair, which may involve a colon resection and prolonged hospital stay, was not in fact needed. Further prospective and randomized study is needed to determine the long-term outcomes of concomitant rectal and vaginal prolapse in those who first undergo a vaginal repair.
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  • 文章类型: Journal Article
    (1)背景:直肠脱垂是一种良性疾病,主要影响女性和老年人。最常见的症状是便秘和失禁。选择的治疗方法是手术,但到目前为止,没有黄金标准方法。这项研究的目的是比较用于治疗直肠脱垂的两种最常见的腹内手术:切除直肠固定术和网状直肠固定术。(2)方法:在本研究中,我们对现有文献进行了全面的系统回顾和荟萃分析,并比较了两种不同方法的并发症发生率,复发率,改善症状率。(3)结果:两种方法在手术时间上差异无统计学意义。逗留时间的长短,总并发症发生率,手术部位感染率,心肺并发症发生率,改善便秘和失禁的发生率,和复发率。(4)结论:我们的研究表明,网状直肠切除术和直肠切除术治疗直肠脱垂的短期和长期结果相似。因此,所使用的手术的决定应该是个性化的,并基于外科医生的偏好和专业知识。
    (1) Background: Rectal prolapse is a benign condition that mainly affects females and the elderly. The most common symptoms are constipation and incontinence. The treatment of choice is surgical, but so far, there has been no gold standard method. The aim of this study is to compare the two most common intrabdominal procedures utilized for treating rectal prolapse: the resection rectopexy and the mesh rectopexy. (2) Methods: In this study, we conducted a thorough systematic review and meta-analysis of the available literature and compared the two different approaches regarding their complication rate, recurrence rate, and improvement of symptoms rate. (3) Results: No statistically significant difference between the two methods was found regarding the operating time, the length of stay, the overall complication rate, the surgical site infection rate, the cardiopulmonary complication rate, the improvement in constipation and incontinence rates, and the recurrence rate. (4) Conclusions: Our study revealed that mesh rectopexy and resection rectopexy for rectal prolapse have similar short- and long-term outcomes. As a result, the decision for the procedure used should be individualized and based on the surgeon\'s preference and expertise.
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  • 文章类型: Editorial
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