目的:观察活动性和非活动性葡萄膜炎患者的眼部结构变化。方法:回顾性研究30例(32只眼)前、中度葡萄膜炎患者和54例54只眼对照组,他们被Trakya大学眼科录取。在研究小组中,14名患者为女性,16例患者为男性,对照组26例志愿者为女性,54名志愿者中有28名是男性。前房深度,轴向长度,眼内压,透镜厚度,中央角膜厚度,角膜曲率测量中的陡峭和平坦值,双眼矫正视力,前房细胞,测量和比较三组(两个葡萄膜炎组-活跃和不活跃-和对照组)之间的玻璃体细胞。结果:在比较轴向长度的中值时,中央角膜厚度,角膜曲率测量的陡峭和平坦的值,活动性葡萄膜炎患者的各项指标均高于对照组,但没有观察到显著差异。前房深度参数值较高,活动性葡萄膜炎患者的晶状体厚度值低于对照组,差异有统计学意义(p<0.05)。没有观察到活跃和不活跃组患者的值的显著结构差异(p>0.05)。结论:只有晶状体厚度和前房深度参数在活动性葡萄膜炎患者中具有统计学意义,与不活跃的葡萄膜炎组相比。与对照组相比,活动性葡萄膜炎患者的前房深度测量值较高,晶状体厚度测量值较低。缩写:AAU=急性前葡萄膜炎,CAU=慢性前葡萄膜炎,AC=前房,IOP=眼内压,IVCM=体内共聚焦显微镜,AS-OCT=前段光学相干断层扫描,UBM=超声生物显微镜,LFP=激光耀斑测光,KP=角质沉淀物,OCT=光学相干断层扫描,AL=轴向长度,ACD=前房深度,LT=透镜厚度,CCT=中央角膜厚度,Ks=角化术的陡峭值,Kf=角化术的平值,AUP=活动性葡萄膜炎患者,IUP=非活动性葡萄膜炎患者,SUN=葡萄膜炎命名法的标准化。
Objective (Aim): To observe the ocular structural changes in active and inactive uveitis patients. Methods: This retrospective study involved 30 patients (32 eyes) with anterior and intermediate uveitis cases and 54 eyes of 54 cases in a control group, who were admitted to the Ophthalmology Department at Trakya University. In the study group, 14 patients were females, 16 patients were males and in the control group 26 volunteers were females, and 28 volunteers were male of the 54 volunteers. Anterior chamber depth, axial length, intraocular pressure, lens thickness, central corneal thickness, steep and flat values in keratometry, corrected visual acuity in both eyes, anterior chamber cells, and vitreous cells were measured and compared between three groups (two uveitis groups - active and inactive - and control group). Results: In the comparison of the median values of axial length, central corneal thickness, and steep and flat values of keratometry, the values of the patients with active uveitis were higher than the ones in the control group in each parameter, but no significant difference was observed. The anterior chamber depth parameter value was higher, the lens thickness value was lower in patients with active uveitis than the values in the control group and the differences were statistically significant (p<0,05). No significant structural differences in the values of the active and inactive group patients (p>0,05) were observed. Conclusions: Only lens thickness and anterior chamber depth parameters were statistically significant in patients with active uveitis, compared with the inactive uveitis group. Anterior chamber depth measurement values were higher and lens thickness measurement values were lower in patients with active uveitis when compared with the control group. Abbreviations: AAU = Acute anterior uveitis, CAU = Chronic Anterior Uveitis, AC = Anterior Chamber, IOP = Intraocular Pressure, IVCM = in vivo Confocal Microscopy, AS-OCT = Anterior Segment Optical Coherence Tomography, UBM = Ultrasound Biomicroscopy, LFP = Laser Flare Photometry, KP = Keratic Precipitates, OCT = Optical Coherence Tomography, AL = Axial Length, ACD = Anterior Chamber Depth, LT = Lens Thickness, CCT = Central Corneal Thickness, Ks = Steep Value of Keratometry, Kf = Flat Value of Keratometry, AUP = Active Uveitis Patients, IUP = Inactive Uveitis Patients, SUN = Standardization of Uveitis Nomenclature.