METHODS: In this study, 74 eyes of 74 patients were measured using the Eyestar 900 SS-OCT and Lenstar LS 900 OLCR. Flat keratometry (K1) and steep keratometry (K2), central corneal thickness (CCT), anterior chamber depth (ACD), lens thickness (LT), and axial length (AL) were measured three times with each device. The repeatability was analyzed with the intrasubject standard deviation, coefficient of variability (CoV), and coefficient of repeatability (CoR) for each instrument. The agreement between the instruments was evaluated with Bland-Altman analysis.
RESULTS: K1, K2 and CCT CoV values were < 0.2%, < 0.4% and < 0.55%, respectively. Higher CoV values were found for ACD and LT ranging from 0.56% to 1.74%. The lowest CoV values were found for the AL measurements (0.03% and 0.06% for the Eyestar 900 and the Lenstar LS 900, respectively). AL measurements provided the highest repeatability, measured with both CoV and CoR values, and the CCT was the parameter with the lowest repeatability. The CCT and LT measurements were statistically significant between the two biometers (P < 0.001). The interval of the limits of agreement was < 0.6 D for K1 and K2, 15.78 µm for CCT, 0.21 mm for ACD, 0.34 mm for LT, and 0.08 mm for AL.
CONCLUSIONS: Both biometers provide repeatable measurements for the different parameters analyzed and can be used interchangeably.
方法:在本研究中,使用Eyestar900SS-OCT和LenstarLS900OLCR测量了74例患者的74只眼。平面角膜曲率(K1)和陡峭角膜曲率(K2),中央角膜厚度(CCT),前房深度(ACD),透镜厚度(LT),每个装置测量三次和轴向长度(AL)。用受试者内标准偏差分析可重复性,变异系数(CoV),和每个仪器的重复性系数(CoR)。用Bland-Altman分析评估仪器之间的一致性。
结果:K1、K2和CCTCoV值<0.2%,<0.4%和<0.55%,分别。发现ACD和LT的CoV值较高,范围为0.56%至1.74%。对于AL测量,CoV值最低(Eyestar900和LenstarLS900分别为0.03%和0.06%)。AL测量提供了最高的可重复性,用CoV和CoR值测量,CCT是重复性最低的参数。CCT和LT测量值在两个生物指标之间具有统计学意义(P<0.001)。K1和K2的协议极限间隔<0.6D,CCT的15.78µm,ACD为0.21mm,LT为0.34mm,和0.08毫米的AL。
结论:两种生物测定器均为所分析的不同参数提供了可重复的测量,并且可以互换使用。