odontogenic tumour

牙源性肿瘤
  • 文章类型: Case Reports
    外周牙源性粘液瘤(POM)是一种罕见的间充质肿瘤,是第一例涉及眼眶和zygoma区的POM报告。
    一名16岁男性出现无痛,他的左颞下区域缓慢增长的肿胀。
    肿瘤的组织病理学检查被诊断为POM。
    患者在全身麻醉下手术切除肿瘤。
    患者在过去的2.5年中一直在随访,没有复发。
    POM是一种罕见的间充质肿瘤。据我们所知,这只是颞下地区POM的第二次报告和粘液瘤的第一次报告,延伸到the骨区域和眼眶侧壁。
    UNASSIGNED: Peripheral odontogenic myxoma (POM) is a rare mesenchymal tumour and it is the first case report of POM involving orbital and zygoma region.
    UNASSIGNED: A 16-year-old male presented with a painless, slow-growing swelling over his left infratemporal region.
    UNASSIGNED: The histopathological examination of the tumour was diagnosed as POM.
    UNASSIGNED: The patient was treated by surgical removal of tumour under general anaesthesia.
    UNASSIGNED: The patient has been under follow-up for the past 2.5 years and there has been no recurrence.
    UNASSIGNED: POM is a rare mesenchymal tumour. To our knowledge, this is only the second report of a POM of the infratemporal region and the first report of a myxoma, which extends into the zygomatic region and lateral wall of the orbit.
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  • 文章类型: Case Reports
    上颌成釉细胞瘤是最罕见的牙源性上皮肿瘤之一,因为80%的成釉细胞瘤在下颌骨内可见。成釉细胞瘤通常是在生命的第三到第四个十年中偶然发现的,由于大多数患者仍然无症状;然而一些患者可能抱怨缓慢增长,无痛肿胀.我们介绍了一例伴有肺转移的上颌成釉细胞瘤,并进行了简要的文献综述。一名17岁男性最初表现为无痛性右侧面部肿胀,which,在考试中,是非招标的,不动的,不规则,粉红色的颜色,有很高的出血倾向,位于粘膜龈沟中,大小约为3x2.5厘米。经过全面的放射学和组织病理学评估,诊断为以丛状和滤泡型共存为特征的成釉细胞瘤。患者接受了右上颌部分切除术,闭孔封闭了硬腭。不幸的是,之后发现了多个局部复发,最终,检测到肺转移。早期和充分的手术切除原发肿瘤对于防止成釉细胞瘤患者的进一步复发至关重要。这可以通过提供严格的术后随访时间表来实现,同时特别注意肺部,脖子,和其他可疑区域,以尽早发现转移。
    Maxillary ameloblastoma is one of the rarest odontogenic epithelial tumors encountered, as 80% of ameloblastomas are seen within the mandible. Ameloblastoma is usually incidentally detected in the third to fourth decades of life, as most patients remain asymptomatic; yet some patients may complain of a slowly growing, painless swelling. We present a case of maxillary ameloblastoma with pulmonary metastasis along with a brief literature review. A 17-year-old male initially presented with painless right facial swelling, which, on examination, was non-tender, immobile, irregular, pink in color, with a high tendency to bleed, and located in the mucogingival sulcus with a size of around 3x2.5 cm. Following comprehensive radiological and histopathological evaluation, the diagnosis of ameloblastoma characterized by the coexistence of plexiform and follicular patterns was confirmed. The patient underwent a partial right maxillectomy with an obturator sealing the hard palate. Unfortunately, multiple local recurrences were identified afterward, and eventually, pulmonary metastasis was detected. Early and adequate surgical resection of the primary tumor is crucial to prevent further recurrences in patients with ameloblastoma. This could be achieved by providing a tight postoperative follow-up schedule while paying special attention to the lungs, neck, and other suspicious areas to detect metastasis as early as possible.
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  • 文章类型: Case Reports
    牙源性纤维粘液瘤通常表现为下颌无痛肿胀,临床上,它生长缓慢,变得良性和无症状。它导致皮质板逐渐扩张,导致牙齿的移动和漂移。根吸收也很常见。肿瘤本质上是局部侵袭性的。还已知其具有高复发率。我们介绍了一名30岁的女性患者的病例,该患者被诊断为上颌骨牙源性纤维粘液瘤,并进行了保守性摘除。X光片显示多房性病变,这可能与成釉细胞瘤混淆,动脉瘤样骨囊肿,或牙源性角化囊肿。因此,有了适当的临床,射线照相,和组织病理学检查,可以做出正确的诊断,并可以计划适当的治疗。
    Odontogenic fibromyxoma typically presents as painless swelling in the jaw, and clinically, it grows slowly, becoming benign and asymptomatic. It causes the cortical plates to expand gradually, which leads to mobility and drifting of the teeth. Root resorption is also common. The tumor is locally aggressive in nature. It is also known to have a high recurrence rate. We present the case of a 30-year-old female patient who was diagnosed and treated for odontogenic fibromyxoma of the maxilla conservatively with enucleation. The radiograph showed a multilocular lesion, which can be confused with ameloblastoma, aneurysmal bone cyst, or odontogenic keratocyst. Hence, with proper clinical, radiographic, and histopathological examination, a correct diagnosis can be made and adequate treatment can be planned.
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  • 文章类型: Journal Article
    牙源性粘液瘤是良性牙源性肿瘤之一,具有侵袭性行为,并表现出缓慢和无症状的扩张,生命的第二个到第三个十年是最有针对性的年龄组。具有很高的女性优势,关于管理,手术治疗是关于这种牙源性病理学的唯一选择,有多种治疗选择。这项研究旨在分析在单个机构中治疗的37例牙源性粘液瘤患者。
    总共,在苏丹的KTDH治疗了37例牙源性粘液瘤患者,并进行了回顾性分析。通过对所有牙源性粘液瘤患者的病历及相关变量的分析,数据使用SPSS统计程序(第23版)进行分析。
    大多数病例为女性(26例70.27%),男性约为(11例29.73%)。在大多数情况下,上颌骨的影响大于下颌骨(25例,67.57%)主要在后段(32例,86.49)。受影响最大的年龄组是病例组(0-20),约为18例(48.65%)。总的来说,其中35例出现肿胀(94.59%),而14例发现牙齿活动度(37.84%)和感觉异常仅在一例(2.70%)中是阳性发现。总的来说,12例(32.43%)患者有与病变相关的拔牙史,复发阳性(64,86%)。
    牙源性粘液瘤是局部侵袭性的。没有手术治疗的黄金标准方案,因此要考虑到每种情况的特征以及相关的术后损伤的复发率,选择最适合和最可靠的治疗方案。
    UNASSIGNED: Odontogenic myxoma is one of the benign mesenchymal odontogenic tumours with aggressive behaviour and showed slow and asymptomatic expansion, the second until the third decade of life is the most targeted age group. With high female preponderance, about the management, surgical management is the only option concerning this odontogenic pathology with a variety of treatment options. This study aims to analyse a series of 37 patients with odontogenic myxoma treated in a single institution.
    UNASSIGNED: In total, 37 patients with odontogenic myxoma were treated at KTDH in Sudan and were retrospectively reviewed. With the analysis of medical records of all patients diagnosed with odontogenic myxoma and the related variables, data were analysed using the SPSS statistical program (version 23).
    UNASSIGNED: Most of the cases were females (26 patients 70.27%), and males were about (11 patients 29.73%). In most of the cases maxilla was affected more than the mandible (25 cases, 67.57%) mostly in its posterior segment (32 cases, 86.49). The most age group affected was the group of cases (0-20) which were about 18 cases (48.65%). In total, 35 of the cases noticed swelling (94.59%), while 14 noticed tooth mobility (37.84%) and paraesthesia was a positive finding in just one case (2.70%). In total, 12 patients (32.43%) had a positive history of tooth extraction related to the lesion, and recurrence was positive in (64, 86%).
    UNASSIGNED: Odontogenic myxoma is locally aggressive. There is no gold standard protocol for surgical treatment so choosing the most suitable and reliable treatment option relay on the operator taking into consideration the characteristic of each case and the recurrence rate with the associated postoperative impairments.
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  • 文章类型: Case Reports
    成釉细胞瘤是最常见的侵袭性良性牙源性颌骨肿瘤。成釉细胞瘤是一种良性上皮牙源性肿瘤,通常发生在下颌骨或上颌骨。临床,放射学和组织病理学报告介绍了一名46岁健康女士的左半下颌骨中的巨大棘皮瘤成釉细胞瘤。切除标本的组织病理学检查显示了棘皮成釉细胞瘤的组织病理学模式。病变的影像学表现显示存在多房性放射性,穿过中线,在成釉细胞瘤中很少发现。由于它的稀有性和缺乏数据,我们借此机会介绍一例晚期棘皮瘤成釉细胞瘤及其手术挑战。
    Ameloblastoma is the most common aggressive benign odontogenic tumour of the jaws. Ameloblastoma is a benign epithelial odontogenic tumour that typically arises in the mandible or maxilla. A clinical, radiographic and histopathological report is presented of a case of giant acanthomatous ameloblastoma in the left hemi mandible of a 46-year-old healthy lady. The histopathological examination of the removed specimen revealed the histopathological pattern of an acanthomatous ameloblastoma. The radiographic appearance of the lesion showed the presence of multilocular radiolucencies, which were crossing the midline, which is rarely found in ameloblastoma. Due to its rarity and lack of data, we take this opportunity to present a case of advanced acanthomatous ameloblastoma and its surgical challenges.
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  • 文章类型: Case Reports
    良性肿瘤中央牙源性纤维瘤(COF)占所有现有牙源性肿瘤的不到1%。下颌或上颌皮质板显示出渐近的多样化。它被描述为良性颌骨肿瘤。射线照相,它主要表现为多房透射线。组织学上,它包括成纤维细胞和成熟的胶原纤维。COF管理的流行选择是摘除,然后拔除相关的牙齿。COF保持了手术后罕见复发机会的记录。在右下前牙区域水肿的38岁女性中检测到COF。手术切除了病灶,并进行了组织病理学检查。文献中已经陈述了许多COF的病例报告。这表明COF的情况并不罕见。
    The benign tumor central odontogenic fibroma (COF) accounts for less than 1% of all the existing odontogenic tumors. The mandibular or maxillary cortical plate is seen to show asymptotic diversification. It has been characterized as a benign jaw neoplasm. Radiographically, it primarily manifests as a multilocular radiolucency. Histologically, it comprises fibroblasts and mature collagen fibers. The popular choice for the management of COFs is enucleation, followed by the extraction of associated teeth. COFs have maintained a track record of showing rare chances of recurrence following surgery. COF was detected in a 38-year-old female who had edema in the lower right front tooth region. The lesion was surgically removed, and a histopathological examination was performed. Many case reports of COF have been stated in the literature. This indicates that cases of COF are not a rare appearance.
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  • 文章类型: Case Reports
    粘液纤维瘤(MF)是一种罕见的,非恶性,具有潜在间充质衍生的牙源性肿瘤。这种特定肿瘤的发生率估计为每年每百万个体约0.05个新病例。MF在10至30岁的年龄范围内表现出更高的发病率。这些肿瘤在女性人群中的患病率较高,下颌骨的主要定位,特别是在后部区域。一位女性患者,66岁,被转介到口腔外科,外科种植和放射学,塞萨洛尼基,希腊,抱怨上颌骨前部有肿瘤性病变和轻度疼痛。临床上,一个实性的触诊分叶肿瘤,在左上切牙观察到正常有色粘膜覆盖。切除活检后,丰富的纤维粘液样基质的微观外观,特别是,粘液样基质与胶原组织混合,被复层鳞状上皮覆盖,提示诊断为周围型黏液纤维瘤。在为期两年的随访中,无复发转诊.此病例说明了对牙龈的每个肿瘤性病变进行适当鉴别诊断以及使用组织病理学检查的必要性。
    The myxofibroma (MF) constitutes an uncommon, non-malignant, odontogenic neoplasm with potential mesenchymal derivation. The occurrence rate of this particular tumor is estimated to be around 0.05 new cases per million individuals annually. MFs exhibit a higher incidence rate within the age range of 10 to 30 years. The prevalence of these tumors is higher among the female population, with a predominant localization in the mandible, specifically in the posterior region. A female patient, 66 years old, was referred to the Department of Oral Surgery, Surgical Implantology and Radiology, Thessaloniki, Greece, complaining of a tumorous lesion in the anterior area of the maxilla and mild pain. Clinically, a solid in palpation lobulated tumor, covered by normal coloured mucosa was observed at the left upper incisor. After the excisional biopsy, the microscopic appearance of abundant fibromyxoid stroma, in particular, myxoid stroma intermingled with collagenous tissue, covered by stratified squamous epithelium, suggested the diagnosis of peripheral myxofibroma. During a 2-year follow-up, no recurrence was referred. This case illustrates the necessity of proper differential diagnosis of every tumorous lesion of the gingiva and of using the histopathological examination.
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  • 文章类型: Case Reports
    牙瘤是一种良性牙源性肿瘤,这被认为是错构瘤。错构瘤不是真正的肿瘤,而是在身体区域发现的异常混合细胞的生长,它们通常会生长。完全发育的牙瘤通常由牙釉质组成,牙本质和牙髓组织,以一种无组织的方式。其中一些也可能含有牙骨质。这些进一步分为复合和复杂,根据他们的临床,影像学和组织学特征。牙瘤通常无症状且生长缓慢,但可能会导致骨骼扩张和牙齿萌出障碍。这些病变通常通过X射线照片中的巧合来诊断。我们正在介绍一名38岁男性右上颌前区的复杂牙瘤和术后裂开的病例和手术治疗。
    Odontoma is a benign odontogenic tumour, which is rather considered hamartoma. Hamartoma is not a true neoplasm, rather a growth of abnormal mixture of cells found in the body area they normally grows. Fully developed odontomas generally consist of enamel, dentin and pulpal tissues, in an unorganised manner. Some of them may contain cementum too. These are further grouped into compound and complex, depending on their clinical, radiographic and histologic features. Odontomas are generally asymptomatic and slow growing, but may cause bone expansion and hinderance in tooth eruption. These lesions are generally diagnosed by coincidence in radiograph. We are presenting a case and surgical management of complex odontoma and post-operative dehiscence in the anterior right maxillary region of a 38-year-old male.
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  • 文章类型: Case Reports
    原始牙源性肿瘤(POT)是一种新描述的良性混合牙源性肿瘤,已被纳入世界卫生组织2017年分类。全世界仅报道了19例符合临床病理诊断标准的病例。我们介绍了全球报告的第20例POT病例,仅是印度报告的第3例。需要考虑POT作为影响10岁以下患者后下颌骨病变的可能诊断,临床医生和病理学家需要了解该实体,并且需要就POT的诊断标准得出更具体的结论,因此有必要报告来自世界不同地区的该实体的每一例病例。连同一名3岁儿童患者的病例报告,我们还在此提供迄今为止报告的病例摘要和文献综述。
    Primordial odontogenic tumour (POT) is a newly described benign mixed odontogenic neoplasm that has been included in the World Health Organization classification 2017. Only 19 cases that conform to the clinico-pathologic criteria for diagnosis have been reported worldwide. We present the 20th case of POT reported worldwide and is only the third case to be reported from India. The need for considering POT as a possible diagnosis in lesions affecting posterior mandible in patients below 10 years, the need for clinicians and pathologists to be aware of this entity and the need to draw more specific conclusions on the diagnostic criteria of POT make it necessary to report every single case of this entity from different parts of the world. Along with the case report in a 3-year-old child patient, we also present here a summary of the cases reported till date and the review of literature.
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  • 文章类型: Case Reports
    腺瘤样牙源性肿瘤(AOT)已有100多年的历史,名称不同,AOT一词由Philippsen和Birn于1969年创造。AOT经常发生在颌骨骨骼的骨内位置,在周围形态很少见。这些是罕见的牙源性肿瘤,占所有牙源性肿瘤的2.2--7.1%,而AOT在卵泡和卵泡外表现的中央或骨内变异,占所有AOT的95.6%。外周变异体表现为牙龈肿块,这可能会导致牙槽骨轻微的沙盘化或可能根本不会影响骨骼。这些外周变异占4.4%或更少,颌骨骨骼的所有AOT。这里,我们提出了一个罕见的病例,在35岁的女性AOT的外周变异,在右侧犬齿前磨牙区域的唇牙龈上看到的尺寸为1.5至2厘米。病变显示13和14颗牙齿区域有明显的骨丢失,造成13的流动性。组织病理学显示肿瘤包囊良好,囊内有化生骨。在肿瘤小滴和淀粉样物质中观察到具有导管和玫瑰花状图案的常规AOT。该病例在临床上表现出适度的攻击行为。
    The Adenomatoid Odontogenic Tumour (AOT) is more than 100 years old, known by different names and the term AOT was coined in 1969 by Philipsen and Birn. AOT frequently occurs in intra-osseous location in gnathic skeleton and rarely seen in peripheral forms. These are rare odontogenic tumours, accounting for 2.2--7.1% of all odontogenic tumours, whereas the central or intraosseous variant of AOT in follicular and extra-follicular presentation, accounts for 95.6% of all AOTs. The peripheral variant presents as a gingival mass, which may cause slight saucerization of alveolar bone or might not affect the bone at all. These peripheral variants constitute 4.4% or less, of all AOTs of the gnathic skeleton. Here, we present a rare case of a peripheral variant of AOT in a 35-years-old female, 1.5 to 2 cm in dimension seen on the labial gingiva in right canine-premolar area. The lesion showed marked bone loss in 13 and 14 teeth region, causing mobility of 13. Histopathology showed a well encapsulated tumour mass with metaplastic bone in the capsule. A conventional AOT with ductal and rosette pattern was seen with tumour droplets and amyloid like material. The case clinically presented a moderately aggressive behaviour.
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