dry needling

干针刺
  • 文章类型: Case Reports
    本研究提出了使用干针(DN)作为干预措施,以支持被诊断患有外侧上髁病的成年人的功能康复。
    回顾,单一主题,实现了AB设计。一名50岁的男性,有6个月的显性左外侧上髁病病史,接受了4周的传统干预(基线阶段;A),然后进行相同的干预,并增加了DN(干预阶段;B)。QuickDASH评估,疼痛数字评定量表(NRS),握力(肘部弯曲和中性),和Maudsley的测试被用作有效性的测量,以及患者进行日常生活活动能力的自我报告(ADLS),仪器ADL,工作,和休闲职业。
    患者在传统治疗的最初4周内进展甚微。他在NRS上最初的7/10疼痛评分没有变化,左手握力(67磅。),或初始QuickDASH得分。DN在第5周开始,从第6周到第8周疼痛从7/10减少到2/10。他在第12周出院,没有疼痛,在QuickDASH上得分为0/100,83磅的非疼痛抓地力。,以及执行所有ADL的能力的自我报告,仪器ADL,工作,和独立的休闲职业。
    对于患有慢性外侧上髁病的个体,如果结合整体方法,干刺似乎是一种有效的干预措施。需要更多的研究来评估干针刺作为一种干预措施,以更大的样本量和随机化来支持功能康复。
    UNASSIGNED: This study presents the use of dry needling (DN) as an intervention to support functional rehabilitation for an adult diagnosed with lateral epicondylosis.
    UNASSIGNED: A retrospective, single subject, AB design was implemented. A 50-year-old male with a six-month history of dominant left lateral epicondylosis received traditional interventions for 4 weeks (baseline phase; A) followed by the same interventions with the addition of DN (intervention phase; B). The QuickDASH assessment, numeric rating scale (NRS) for pain, grip strength (elbow flexed and neutral), and Maudsley\'s test were used as measures of effectiveness along with patient self-report of ability to perform activities of daily living (ADLS), instrumental ADLs, work, and leisure occupations.
    UNASSIGNED: The patient made minimal progress for the initial 4 weeks of traditional treatment. There were no changes to his initial pain rating of 7/10 on the NRS, left hand grip strength (67 lbs.), or initial QuickDASH score. DN was initiated at week five with a reduction in pain from 7/10 to 2/10 from weeks six to eight. He was discharged at week 12 with no pain, a score of 0/100 on the QuickDASH, non-painful grip of 83 lbs., and a self-report of the ability to perform all ADLs, instrumental ADLs, work, and leisure occupations independently.
    UNASSIGNED: Dry needling appears to have been an effective intervention when integrated with a holistic approach for an individual with chronic lateral epicondylosis. More research is needed to evaluate dry needling as an intervention to support functional rehabilitation with a larger sample size and randomization.
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  • 文章类型: Journal Article
    这项研究的目的是比较压缩对比疗法(CT)和干针疗法(DN)对肌张力(MT)的急性影响,肌肉力量(Fmax),压力痛阈值(PPT),和前臂肌肉疲劳后的灌注(PU)(例如,radium屈肌)在格斗运动运动员中。采用单盲随机对照试验。参与者首先接受了肌肉疲劳诱导,其中包括在5秒周期内以其最大自愿收缩的60%维持等距手柄。随后是暴露于一种再生疗法。45名参与者被随机分为三组:CT/DN(n=15),CT/ShDN(n=15),和ShCT/DN(n=15)。假条件(Sh)涉及该技术的模拟版本。在四个时间点进行测量:(i)休息时;(ii)运动后立即导致疲劳状态;(iii)治疗后5分钟(PostTh5min);(iv)治疗后24小时(PostTh24h)。每个参与者都暴露在一个实验条件和一个对照条件下,从而在两个会议中进行评估。在Th5min后发现两组之间的MT存在显着差异(p=0.005),以及在PU后5分钟(p<0.001)和PU后24小时(p<0.001)。所有组在治疗后5分钟时与肌肉立即疲劳后相比显示出显著改善。作为结论,在5分钟的肌肉疲劳诱导后,CT/DN似乎对增强MT和PU明显更好。使用任一CT,DN,或两者结合,建议提高肌肉功能和性能的恢复,有利于恢复并可能加快性能增强。
    The aim of this study was to compare the acute effects of compression contrast therapy (CT) and dry needling therapy (DN) on muscle tension (MT), muscle strength (Fmax), pressure pain threshold (PPT), and perfusion (PU) following fatigue of forearm muscles (e.g., flexor carpi radialis) in combat sports athletes. A single-blind randomized controlled trial was employed. Participants first underwent muscle fatigue induction, which involved sustaining an isometric handgrip at 60% of their maximum voluntary contraction in 5-second cycles. This was followed by exposure to one of the regenerative therapies. Forty-five participants were randomly assigned to one of three groups: CT/DN (n = 15), CT/ShDN (n = 15), and ShCT/DN (n = 15). The sham condition (Sh) involved a simulated version of the technique. Measurements were taken at four time points: (i) at rest; (ii) immediately after exercise that led to a state of fatigue; (iii) 5 minutes after therapy (PostTh5min); and (iv) 24 hours after therapy (PostTh24h). Each participant was exposed to one experimental condition and one control condition, thereby undergoing evaluation in two sessions. Significant differences between groups were found in MT during the PostTh5min (p = 0.005), as well as in PU during the PostTh5min (p < 0.001) and PU during the PostTh24h (p < 0.001). All groups showed significant improvements at 5 minutes post-therapy compared to immediately post-muscle fatigue. As conclusions, CT/DN seems to be significantly better for enhancing MT and PU after 5 minutes of muscle fatigue induction. Using either CT, DN, or both combined is recommended to enhance the recovery of muscle functionality and properties, favoring recovery and potentially speeding up performance enhancement.
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  • 文章类型: Journal Article
    长头肱二头肌肌腱病,前肩疼痛的常见来源,可能导致不适和功能减弱。这项研究的目的是评估干刺和经皮神经电刺激对这些患者的疗效。
    30例患者随机分为干刺和经皮神经电刺激组,并在治疗前进行评估。治疗后8天和15天使用视觉模拟量表,肩痛和残疾指数,压力痛阈值,组织硬度,和肱二头肌周围积液。
    两种治疗方法均显着降低了视觉模拟评分(p<0.001),短期(p<0.01),和中期效应(p<0.01)。在短期和中期影响下,干针治疗肩痛和残疾指数分量表的疼痛(p<0.01)和残疾(p<0.03)优于经皮神经电刺激,分别。两种治疗后压力痛阈值均增加,但持续8天以上。两种治疗均未显示肱二头肌长头的组织硬度有任何改善。值得注意的是,在短期和中期效果上,只有干刺组显着减少了二头肌肌腱周围积液(p<0.01)。
    干刺在减轻疼痛和残疾方面的效果不劣于经皮神经电刺激,在减少肱二头肌肌腱周围积液方面的效果甚至更好(见图形摘要)。
    中国医科大学附属医院机构审查委员会(CMUH107-REC2-101)批准了这项研究,并在ClinicalTrials.gov上注册了标识符NCT03639454。
    干针刺和经皮神经电刺激均可有效减轻肱二头肌肌腱病的长头疼痛。干针法在短期和中期疼痛和残疾缓解方面优于经皮神经电刺激,分别。与经皮神经电刺激相比,干刺在减少二头肌肌腱周围积液方面表现出更好的效果。
    UNASSIGNED: Long head of biceps brachii tendinopathy, a frequent source of anterior shoulder pain, may lead to discomfort and diminished function. The objective of this study is to assess the efficacy of dry needling and transcutaneous electrical nerve stimulation in these patients.
    UNASSIGNED: Thirty patients were randomized into dry needling and transcutaneous electrical nerve stimulation groups and assessed before treatment, 8 and 15 days after treatment using a visual analogue scale, shoulder pain and disability index, pressure pain threshold, tissue hardness, and biceps peritendinous effusion.
    UNASSIGNED: Both treatments significantly reduced the visual analogue scale in immediate (p < 0.001), short-term (p < 0.01), and medium-term effects (p < 0.01). Dry needling outperformed transcutaneous electrical nerve stimulation for the pain (p < 0.01) and disability (p < 0.03) subscales of the shoulder pain and disability index in the short-term and medium-term effects, respectively. Pressure pain threshold increased after both treatments but didn\'t last beyond 8 days. Neither treatment showed any improvements in tissue hardness of the long head of biceps brachii muscle. Notably, only the dry needling group significantly reduced biceps peritendinous effusion in both short-term and medium-term effects (p < 0.01).
    UNASSIGNED: Dry needling showed non-inferior results to transcutaneous electrical nerve stimulation in reducing pain and disability and demonstrated even superior results in reducing biceps peritendinous effusion (see Graphical Abstract).
    UNASSIGNED: The Institutional Review Board of the China Medical University Hospital (CMUH107-REC2-101) approved this study, and it was registered with Identifier NCT03639454 on ClinicalTrials.gov.
    Both dry needling and transcutaneous electrical nerve stimulation effectively reduced pain in the long head of biceps brachii tendinopathy.Dry needling outperformed transcutaneous electrical nerve stimulation in short-term and medium-term pain and disability relief, respectively.Dry needling demonstrated superior results in reducing biceps peritendinous effusion compared to transcutaneous electrical nerve stimulation.
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  • 文章类型: Journal Article
    目的:比较Prolotherapy和深干针(DDN)联合治疗缓解颞下颌关节(TMJ)前盘移位症状的效果。
    方法:临床试验随机分配40名患者。(对照组)患者接受了四次关节内和咬肌DDN会话,而(研究组)患者接受了精确的技术,然后进行了Prolosolution注射。基线术前测量包括最大切缝开口(MIO),听诊点击的存在,和视觉模拟评分(VAS),一次后重复进行术后测量,两个,五,还有八个月.
    结果:在研究结束时,所有患者均表示疼痛MIO和咔嗒声明显改善。组间和组内比较显示,对照组在5个月和8个月后的疼痛评分值明显高于研究组。研究组MIO校准比对照组更显著,在任何时间间隔内,两组之间关于点击存在的差异都不显著。单击和VAS值之间的关联,在点击和MIO之间,在VAS值和MIO升高之间,试验组阳性,对照组阴性。
    结论:葡萄糖普罗疗法和DDN是有益的。然而,Prolotherapy证明更显著,持续,与症状的长期缓解和MIO增加相关。
    结论:该研究评估了除穿刺针的影响外,右旋糖修复疗法对缓解TMJ前椎间盘移位体征的唯一作用。
    背景:该研究在www上注册。
    结果:gov(#:NCT05821985),AhmedNagiAlghandour。
    OBJECTIVE: to compare the combined effect of Prolotherapy and Deep Dry Needling (DDN) versus DDN effect on relieving the symptoms of Temporomandibular joint (TMJ) anterior disc displacement.
    METHODS: The clinical trial randomly allocated forty patients. The (control group) patients received four intraarticular and masseteric DDN sessions, while the (study group) patients were subjected to the exact technique followed by Prolosolution injection. The baseline preoperative measurements included Maximal interincisal opening (MIO), auscultation of the presence of clicking, and Visual Analogue Scale (VAS), which were repeated for postoperative measurements after one, two, five, and eight months.
    RESULTS: By the end of the study, all patients expressed apparent improvement in pain MIO and clicking. The inter- and intragroup comparison revealed that the pain score values of the control group after five and eight months were significantly higher than those of the study group. The study group demonstrated more significant MIO calibration than the control group, with insignificant differences between both groups regarding the presence of clicking at any time interval. The associations between clicking and VAS values, between clicking and MIO, and between VAS values and increased MIO were positive in the test group and negative in the control group.
    CONCLUSIONS: Dextrose Prolotherapy and DDN were beneficial. However, Prolotherapy demonstrated more significant, sustained, and correlated long-term alleviation of symptoms and increased MIO.
    CONCLUSIONS: The study assesses the sole effect of dextrose prolotherapy on relieving the signs of TMJ anterior disc displacement apart from the impact of the penetrating needle.
    BACKGROUND: The study was registered on www.
    RESULTS: gov (#: NCT05821985) by Ahmed Nagi Alghandour.
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  • 文章类型: Journal Article
    背景:颈源性头痛很常见,被认为是上颈椎功能障碍的原因。地图集的活动性和位置已被确定为上颈椎功能障碍的原因。地图集的活动性完全受枕下肌的控制。斜头炎下肌收缩时对地图集有旋转作用。这项研究评估了干针电刺激引起的左斜头炎下肌收缩对寰枢关节中寰椎的位置和活动性的直接影响。方法:31名受试者参与本受试者内重复测量研究设计。每位受试者都接受了预先测量的颈部弯曲旋转测试,触诊图谱位置,用肌肉骨骼超声成像测量右斜头炎下肌的长度。在斜头炎下肌两次五秒钟的强直收缩后,重复了预先测量。结果:干预后分析显示右斜头肌下肌长度有明显变化。这种长度变化与介入后立即触诊的位置默认位置相关。结论:左斜头炎下肌的两个五秒强直收缩立即影响了寰枢关节中寰枢关节的位置。在我们的主题中,90%在左旋转中显示位置默认值,这与颈部屈曲旋转试验的变化有关。这项研究支持枕下肌张力可导致活动功能障碍的观点,因此,如宫颈源性头痛。
    Background: cervicogenic headaches are common and are believed to be the cause of dysfunction in the upper cervical spine. The mobility and the position of the atlas have been identified as a cause of upper cervical dysfunction. The mobility of the atlas is entirely under the control of the suboccipital muscles. The oblique capitis inferior muscle has a rotatory effect on the atlas when contracted. This study evaluated the immediate effects of a dry needling electrical stimulation-induced contraction of the left oblique capitis inferior muscle on the position and mobility of the atlas in the atlantoaxial joint. Methods: thirty-one subjects participated in this within-subject repeated measure study design. Each subject underwent a pre-measures neck flexion rotation test, palpation of the atlas position, and measurement of the length of the right oblique capitis inferior muscle with musculoskeletal ultrasound imaging. The pre-measures were repeated after two five-second tetanic contractions of the oblique capitis inferior muscle. Results: post-intervention analysis revealed significant changes in the length of the right oblique capitis inferior muscle. This length change correlated with the palpated positional default position immediately after the intervention. Conclusions: two five-second tetanic contractions of the left oblique capitis inferior muscle immediately affected the position of the atlas in the atlantoaxial joint. In our subjects, 90% displayed a positional default in the left rotation, and this was correlated with a change in the neck flexion rotation test. This study supports the notion that suboccipital muscle tonicity can result in mobility dysfunction and, thus, conditions such as cervicogenic headaches.
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  • 文章类型: Journal Article
    肌肉骨骼疾病,尤其是慢性肌肉疼痛,对公众健康有重大影响,影响全世界数百万人。这篇综述探讨了肌筋膜疼痛的诊断和治疗的最新进展,重点介绍了触发点理论的精细化应用。这个理论现在包含了一个复杂的模型,融合了生物力学和神经生理机制,对于理解疼痛的开始和持续至关重要,并需要有针对性的治疗干预措施。利用有条理的方法,本文将肌肉疼痛分为三种类型:肌肉肚皮痛,起源-插入疼痛,并引用疼痛,如最新版“肌筋膜疼痛和功能障碍-触发点手册”所述。这种分类通过为每种类型的疼痛建立特定的治疗方案来提高诊断精度和治疗效果。本文讨论了各种治疗方法的含义,如干针刺和手动治疗,由经验得出的触发点图表提供信息。这些图表有助于精确定位疼痛源的确切位置和定制治疗计划。此外,本综述严格评估了触发点图表的演变性质,并提出了疼痛管理的整体方法.它强调了整合生物力学的必要性,运动学,和代偿机制,以提供全面的理解,使从业者不仅能够解决症状性疼痛,而且还解决肌肉骨骼疾病的根本原因,从而提高临床环境中的长期患者护理结果。
    Musculoskeletal disorders, especially chronic muscle pain, have a significant impact on public health, affecting millions worldwide. This review examines recent advancements in the diagnosis and management of myofascial pain, with a focus on the refined application of trigger point theory. This theory now incorporates an intricate model that blends biomechanical and neurophysiological mechanisms, essential for understanding the initiation and persistence of pain, and necessitating targeted therapeutic interventions. Utilizing a methodical approach, this paper categorizes muscle pain into three types: Muscle Belly Pain, Origin-Insertion Pain, and Referred Pain, as delineated in the most recent edition of \"Myofascial Pain and Dysfunction-The Trigger Point Manual.\" Such classification enhances diagnostic precision and therapeutic effectiveness by establishing a specific treatment protocol for each type of pain. The paper discusses the implications of various treatments, such as dry needling and manual therapy, which are informed by empirically derived trigger point charts. These charts are instrumental in pinpointing the exact locations of pain sources and customizing treatment plans. Moreover, this review critically assesses the evolving nature of trigger point charts and champions a holistic approach to pain management. It underscores the necessity of integrating biomechanics, kinesiology, and compensatory mechanisms to provide a comprehensive understanding that allows practitioners to address not only symptomatic pain but also the root causes of musculoskeletal disorders, thereby enhancing long-term patient care outcomes in clinical environments.
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  • 文章类型: Journal Article
    背景:干针(DN)通常用于治疗各种神经肌肉综合征。它可有效减少中风和其他神经系统疾病的痉挛。当前的研究探讨了超声引导的干针刺对中风患者比目鱼肌痉挛和厚度的直接影响。
    方法:获得了D.Y.Patil理疗学院的机构亚伦理委员会的批准,浦那。该试验在印度临床试验注册中心注册。根据改良的Ashworth量表(MMAS)选择了30名比目鱼肌痉挛的1至4级中风幸存者。还使用改良的Tardeau量表(MTS)和H反射评估了痉挛。通过超声检查(USG)评估比目鱼肌结构。参与者接受了一次痉挛的比目鱼肌DN。评估DN前和即时后结局指标。
    结果:根据USG的调查结果,干针处理后,比目鱼肌厚度显着增加了2.67mm(p<0.001)。MMAS显示踝关节足底屈肌痉挛减少1.47(p<0.001)。注意到H-反射值显著降低1.4mV(p<0.001)。MTS还显示踝关节运动范围显著增加2.7(p<0.001)。所有这些都表明DN后痉挛立即减少。
    结论:根据当前研究的结果,我们可以得出结论,在卒中患者中,单次接受USG指导的DN对减轻比目鱼肌痉挛和增加肌肉厚度具有直接的有益效果.
    BACKGROUND: Dry needling (DN) is commonly used to treat various neuromuscular syndromes. It is effective in reducing spasticity in stroke and other neurological conditions. The current study explores the immediate effect of ultrasound-guided dry needling on soleus muscle spasticity and thickness in individuals with stroke.
    METHODS: Approval was obtained from the Institutional Sub-ethics Committee of Dr. D. Y. Patil College of Physiotherapy, Pune. The trial was registered with the Clinical Trials Registry of India. Thirty stroke survivors having soleus muscle spasticity ranging from grade 1 to 4 on the Modified Modified Ashworth Scale (MMAS) were selected. Spasticity was also assessed using the Modified Tardeau Scale (MTS) and H-reflex. Soleus muscle architecture was assessed by using ultrasonography (USG). Participants received a single session of DN for the spastic soleus muscle. Pre and immediate post-DN outcome measures were assessed.
    RESULTS: Based on USG findings, the thickness of the soleus muscle significantly increased by 2.67 mm (p<0.001) after dry needling treatment. The MMAS showed decreased spasticity by 1.47 (p<0.001) for ankle plantar flexors. A significant reduction of H-reflex values by 1.4 mV (p<0.001) was noted. The MTS also showed a significant increase in the range of ankle motion by 2.7 (p<0.001). All these indicate an immediate reduction of spasticity following DN.
    CONCLUSIONS: Based on the findings of the current study, we can conclude that a single session of USG-guided DN has an immediate beneficial effect on reducing soleus muscle spasticity and increased muscle thickness in individuals with stroke.
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  • 文章类型: Journal Article
    运动员肌筋膜疼痛的治疗需要一套旨在快速有效的康复技术。在这种情况下,干针(DNY)由于其在短期内减轻疼痛的能力而显示出有趣的结果。因此,本研究的目的是探讨DNY在治疗头顶运动员肩关节肌筋膜疼痛中的作用.PubMed,截至2024年3月,Scopus和WebofScience进行了筛选,以确定符合以下纳入标准的研究:高架运动员肩痛,采用DNY方法治疗肌筋膜触发点(MTrP),RCT,病例对照研究,可行性研究作为研究设计。排除标准是不包括运动员的研究,不关注DNY治疗MTrPs的研究,其他评论,没有全文可用性和以英语以外的语言编写的论文。在399篇文章中,165个被排除为重复。在筛选的234篇文章中,只有6篇文章符合纳入标准。共有6项研究纳入系统评价。初步结果显示,DNY在短期迅速改善疼痛;然而,对于最小次数和治疗间隔时间仍未达成共识.主要发现报告了感知疼痛的快速潜在减少,肩膀残疾和肌肉力量的增加;在这种情况下,DNY可能是运动康复环境中的有效解决方案。
    The treatment of myofascial pain in athletes requires a set of rehabilitation techniques that aim to be effective quickly. In this context, dry needling (DNY) has shown interesting results due to its ability to reduce pain in the short term. Thus, the aim of this study was to investigate the role of DNY in managing myofascial shoulder pain in overhead athletes. PubMed, Scopus and Web of Science were screened up to March 2024, to identify studies that met the following inclusion criteria: overhead athletes with shoulder pain with a DNY approach for myofascial trigger points (MTrPs), RCT, case-control study, feasibility study as the study design. Exclusion criteria were studies that did not include athletes, studies that did not focus on the treatment of MTrPs with DNY, other reviews, no full-text availability and papers written in a language other than English. Out of 399 articles, 165 were excluded as duplicates. Of the 234 articles screened, only 6 articles met the inclusion criteria. A total of 6 studies were included in the systematic review. Initial results showed that DNY improved pain rapidly and in the short term; however, there is still no consensus on the minimum number and the interval between treatments. Major findings reported a rapid potential decrease in perceived pain, shoulder disability and an increase in muscle strength; in this scenario, DNY might be a valid solution in a sports rehabilitation setting.
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  • 文章类型: Journal Article
    这项研究旨在研究潜在的安慰剂和nocebo效应对经皮针头电解(PNE)的疼痛感知的影响。
    在这项对三臂随机双盲对照试验的二次分析中,本研究调查了48名18~45岁髌腱病运动参与者的会中和会期疼痛感知数据.参与者分为3个平行组:“无假组”[PNE干预],“单假手术组”[使用干针刺进行假手术],和“双假手术组”[使用假针进行假手术]。每组在8周内接受4次针对the肌腱的针刺疗法,并被指示对患侧的股四头肌进行单侧偏心运动程序。临床和针头相关的疼痛进行评估之前,during,并在每次治疗后使用视觉模拟量表。
    两组间在疼痛减轻方面没有发现差异(P=0.424),尽管自第一次治疗以来所有组的临床疼痛均有所减轻(P<0.001)。此外,尽管双假手术组显示在针头干预期间报告针头相关疼痛的参与者百分比较低(P=0.005),两组间针刺干预后针刺相关疼痛强度相似(P=0.682).此外,任何针刺干预后疼痛感觉的持续时间没有组间差异(P=0.184),在许多情况下超过24小时。
    髌腱病患者的针刺疗法容易引起临床疼痛的安慰剂效应和针刺相关疼痛的无效应。治疗肌肉骨骼疼痛的临床医生和物理治疗师在常规使用针头技术之前,应考虑附加值和潜在的作用机制。
    UNASSIGNED: This study aimed to investigate the influence of potential placebo and nocebo effects on pain perception of percutaneous needle electrolysis (PNE) in individuals with patellar tendinopathy.
    UNASSIGNED: In this secondary analysis of a three-arm randomized double-blinded controlled trial, intra and inter-session pain perception data from 48 sporting participants with patellar tendinopathy between 18 and 45 years were investigated. Participants were divided into 3 parallel groups: \"no-sham group\" [PNE intervention], \"single-sham group\" [sham PNE by using dry needling], and \"double-sham group\" [sham PNE by using sham needles]. Every group received 4 sessions of the needling therapies targeting the patellar tendon over 8 weeks and was instructed to perform a unilateral eccentric exercise program of the quadriceps muscle on the affected side. Clinical and needle-related pain was assessed before, during, and after each treatment session using a visual analog scale.
    UNASSIGNED: No differences were found between groups intra- or inter-session in terms of pain reduction (P = 0.424) despite clinical pain decreased in all groups since the first treatment session (P < 0.001). Furthermore, although the double-sham group showed a lower percentage of participants reporting needle-related pain during needle intervention (P = 0.005), the needle-related pain intensity after needle intervention was similar between groups (P = 0.682). Moreover, there were no group differences for the duration of pain sensation after any needle intervention (P = 0.184), extending in many cases beyond 24 h.
    UNASSIGNED: Needling therapies for individuals with patellar tendinopathy are prone to elicit placebo effects regarding clinical pain and nocebo effects regarding needling-related pain. Clinicians and physical therapists treating musculoskeletal pain conditions should consider the added value and potential mechanisms of action before routinely using needle techniques.
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  • 文章类型: Journal Article
    背景:血管性认知障碍(VCI)持续损害认知和进行日常生活活动的能力,严重影响患者的生活质量。先前的研究报道,血清铁代谢紊乱和大脑中铁沉积可导致炎症,异常的蛋白质聚集和变性,中枢神经系统大量神经元凋亡,这反过来又导致认知过程的逐步下降。我们之前的临床研究发现针灸治疗VCI是一种安全有效的干预措施,但具体机制有待进一步探索。
    目的:本试验旨在评价通都醒神针刺法的临床疗效,探讨其是否能通过调节脑铁沉积和机体铁代谢来改善VCI。
    方法:总共,42名VCI患者和21名健康个体将参与这项临床试验。将42例VCI患者随机分为针刺组和对照组,而21名健康个体将进入健康对照组。对照组和针刺组均接受常规药物治疗和认知康复训练。此外,针刺组用通度醒神电针治疗,每次30分钟,每周6次,共4周。同时,健康对照组将不接受任何干预。所有3组将接受脑铁沉积的基线评估,血清铁代谢,和入学后的神经心理学测试。针灸组和对照组将在治疗4周结束时再次进行评估,如前所述。通过比较各组之间的神经心理学测试成绩,我们将研究通都醒神针刺治疗VCI的疗效。此外,我们将测试神经心理学测试成绩之间的相关性,脑铁沉积,及机体铁代谢指标,探讨通毒醒神针刺治疗VCI的可能机制。
    结果:目前正在招募参与者。第一位参与者于2023年6月注册,这标志着实验的正式开始。截至论文提交之时,有23人参加。招聘过程预计将持续到2025年6月,届时将开始处理和分析数据。截至2024年5月15日,多达30人参加了这项临床试验。
    结论:本研究将提供通都醒神针刺对VCI患者脑铁沉积以及躯体铁代谢的影响。这些结果将有助于证明通都醒神针法能否通过调节脑铁沉积和机体铁代谢来改善VCI,为针灸疗法在VCI康复中的广泛应用提供临床和理论依据。
    背景:中国临床注册管理机构ChiCTR2300072188;https://tinyurl.com/5fcydtkv.
    PRR1-10.2196/56484。
    BACKGROUND: Vascular cognitive impairment (VCI) persistently impairs cognition and the ability to perform activities of daily living, seriously compromising patients\' quality of life. Previous studies have reported that disorders of serum iron metabolism and iron deposition in the brain can lead to inflammation, abnormal protein aggregation and degeneration, and massive neuronal apoptosis in the central nervous system, which in turn leads to a progressive decline in cognitive processes. Our previous clinical studies have found acupuncture to be a safe and effective intervention for treating VCI, but the specific mechanisms require further exploration.
    OBJECTIVE: The objective of the trial is to evaluate the clinical efficacy of Tongdu Xingshen acupuncture and to investigate whether it can improve VCI by regulating brain iron deposition and body iron metabolism.
    METHODS: In total, 42 patients with VCI and 21 healthy individuals will participate in this clinical trial. The 42 patients with VCI will be randomized into acupuncture and control groups, while the 21 healthy individuals will be in the healthy control group. Both the control and acupuncture groups will receive conventional medical treatment and cognitive rehabilitation training. In addition, the acupuncture group will receive electroacupuncture treatment with Tongdu Xingshen for 30 minutes each time, 6 times a week for 4 weeks. Meanwhile, the healthy control group will not receive any intervention. All 3 groups will undergo baseline assessments of brain iron deposition, serum iron metabolism, and neuropsychological tests after enrollment. The acupuncture and control groups will be evaluated again at the end of 4 weeks of treatment, as described earlier. By comparing neuropsychological test scores between groups, we will examine the efficacy of Tongdu Xingshen acupuncture in treating VCI. Additionally, we will test the correlations between neuropsychological test scores, brain iron deposition, and body iron metabolism indexes to explore the possible mechanisms of Tongdu Xingshen acupuncture in treating VCI.
    RESULTS: Participants are currently being recruited. The first participant was enrolled in June 2023, which marked the official start of the experiment. As of the submission of the paper, there were 23 participants. The recruitment process is expected to continue until June 2025, at which point the processing and analysis of data will begin. As of May 15, 2024, up to 30 people have been enrolled in this clinical trial.
    CONCLUSIONS: This study will provide data on the effects of Tongdu Xingshen acupuncture on cerebral iron deposition as well as somatic iron metabolism in patients with VCI. These results will help to prove whether Tongdu Xingshen acupuncture can improve VCI by regulating brain iron deposition and body iron metabolism, which will provide the clinical and theoretical basis for the wide application of acupuncture therapy in VCI rehabilitation.
    BACKGROUND: China Clinical Registration Agency ChiCTR2300072188; https://tinyurl.com/5fcydtkv.
    UNASSIGNED: PRR1-10.2196/56484.
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