digital vasculopathy

  • 文章类型: Case Reports
    在撒哈拉以南非洲地区温暖的气候中,雷诺现象作为急性肢体缺血的原因并不常见,因为它通常被认为是寒冷天气中常见的疾病。非洲黑人中结缔组织疾病的患病率正在增加,这些情况与继发性雷诺现象和缺血性数字病变有关。我们介绍了一名36岁的女性,患有皮肌炎/系统性硬化症重叠和继发性雷诺现象,在加纳的一家三级医院中出现急性肢体缺血(所有手指的湿性坏疽)。出现急性肢体缺血的年轻患者也应筛查潜在的结缔组织疾病。在结缔组织病患者中,数字血管病变的发作可以是快速和进行性的,因此,治疗必须及时全面,才能获得更好的临床疗效.
    没有声明。
    Raynaud\'s phenomenon as a cause of acute limb ischaemia in the warmer climates of Sub-Saharan Africa region is uncommon because it is usually thought of as a disease common in cold weather. The prevalence of connective tissue diseases among Black Africans is increasing, and these conditions are associated with secondary Raynaud\'s phenomenon and ischaemic digital lesions. We present the case of a 36-year old female with dermatomyositis/systemic sclerosis overlap and secondary Raynaud\'s phenomenon who presented with acute limb ischemia (wet gangrene of all digits) in a Tertiary Hospital in Ghana. Young patients presenting with acute limb ischaemia should also be screened for an underlying connective tissue disease. In patients with connective tissue disease, the onset of digital vasculopathy can be rapid and progressive, hence treatment must be prompt and comprehensive to enable better clinical outcomes.
    UNASSIGNED: None declared.
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  • 文章类型: Consensus Development Conference
    OBJECTIVE: Digital vasculopathy (comprising RP, digital ulceration and critical digital ischaemia) is responsible for much of the pain and disability experienced by patients with SSc. However, there is a limited evidence base to guide clinicians in the management of SSc-related digital vasculopathy. Our aim was to produce recommendations that would be helpful for clinicians, especially for those managing patients outside specialist centres.
    METHODS: The UK Scleroderma Study Group set up several working groups to develop a number of consensus best practice pathways for the management of SSc-specific complications, including digital vasculopathy.
    RESULTS: This overview presents the background and best practice consensus pathways for SSc-related RP, digital ulceration and critical ischaemia. Examples of drug therapies, including doses, are suggested in order to inform prescribing practice.
    CONCLUSIONS: A number of treatment algorithms are provided that are intended to provide the clinician with accessible reference tools for use in daily management.
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