关键词: Raynaud’s phenomenon critical digital ischaemia digital ulcer digital vasculopathy scleroderma systemic sclerosis

Mesh : Algorithms Disease Management Fingers / blood supply pathology Humans Ischemia / etiology therapy Practice Patterns, Physicians' Raynaud Disease / etiology therapy Scleroderma, Systemic / complications Ulcer / etiology therapy United Kingdom Vascular Diseases / etiology therapy

来  源:   DOI:10.1093/rheumatology/kev201   PDF(Sci-hub)

Abstract:
OBJECTIVE: Digital vasculopathy (comprising RP, digital ulceration and critical digital ischaemia) is responsible for much of the pain and disability experienced by patients with SSc. However, there is a limited evidence base to guide clinicians in the management of SSc-related digital vasculopathy. Our aim was to produce recommendations that would be helpful for clinicians, especially for those managing patients outside specialist centres.
METHODS: The UK Scleroderma Study Group set up several working groups to develop a number of consensus best practice pathways for the management of SSc-specific complications, including digital vasculopathy.
RESULTS: This overview presents the background and best practice consensus pathways for SSc-related RP, digital ulceration and critical ischaemia. Examples of drug therapies, including doses, are suggested in order to inform prescribing practice.
CONCLUSIONS: A number of treatment algorithms are provided that are intended to provide the clinician with accessible reference tools for use in daily management.
摘要:
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