背景:这项研究的目的是确定解剖变异的患病率(肾,血管和泌尿外科)和活体肾脏供体候选人(LKDC)的获得性肾脏病变。
方法:这是2003年4月至2014年9月期间转诊至我们中心的所有LKDC的回顾性研究。在491LKDC中,189人最初因医疗原因(n=140)或其他原因(n=49)被排除在外,没有接受放射学评估.总的来说,302进行了放射学评估(血管CT或MRI),以预期捐赠,而226/302(73.5%)可以捐赠肾脏。
结果:在178/302(58.9%)的LKDC中观察到一种或多种解剖变异和/或获得性异常。最常见的是动脉变异或异常(多个动脉,纤维发育不良,动脉瘤,狭窄≥70%),在39.3%的LKDC中观察到,其次是静脉异常(27.8%)。在5.6%的LKDC中观察到肾结石,在3%的LKDC中发现了尿路异常(重复/输尿管双重)。没有诊断出恶性肿瘤,虽然发现了4例良性肿瘤(1.3%),其中一个需要额外的调查。
结论:我们发现LKDC人群中解剖变异和获得性异常的患病率很高。然而,这些发现导致只有4%的候选人被排除在外,因为他们没有禁止捐赠,或者,在大多数情况下,可以使用对侧肾脏。
方法:3.
BACKGROUND: The aim of this study was to determine the prevalence of anatomic variations (renal, vascular and urological) and acquired renal pathologies in living kidney donor candidates (LKDC).
METHODS: This is a retrospective study of all LKDC referred to our center between April 2003 and September 2014. Of the 491 LKDC, 189 were initially excluded for medical reasons (n=140) or others reasons (n=49), without undergoing a radiological assessment. In total, 302 had a radiological assessment (angio-CT or MRI) in anticipation of the donation and 226/302 (73.5%) could donate a kidney.
RESULTS: One or more anatomical variations and/or acquired abnormalities were observed in 178/302 (58.9%) of the LKDC. The most frequent were arterial variations or abnormalities (multiple arteries, fibrodysplasia, aneurysms, stenosis≥70%) which where observed in 39.3% of the LKDC, followed by the venous abnormalities (27.8%). Kidney stones were observed in 5.6% of the LKDC and the urinary abnormalities (duplication/ureteral bifidity) were found in 3% of the LKDC. No malignant tumour was diagnosed, while 4 benign tumours (1.3%) were identified, and one of them required additional investigations.
CONCLUSIONS: We found a high prevalence of anatomical variations and acquired abnormalities in a population of LKDC. However, these findings resulted in the exclusion of only 4% of the candidates, because they did not contraindicate the donation or, in most of cases, the contralateral kidney could be used.
METHODS: 3.