United States Dept. of Health and Human Services

美国部门.健康与人类服务
  • 文章类型: Journal Article
    背景:这项研究估计了美国卫生与人类服务部的收益和成本,“我们可以做这项COVID-19公共教育运动(运动)和相关的疫苗接种相关影响。
    方法:使用每周媒体市场和国家运动支出来估计每周第一剂疫苗接种,如果没有运动,每周由Campaign指定的完整疫苗接种,以及相应的COVID-19病例,住院治疗,避免了死亡。使用估计的发病率和死亡率降低以及统计寿命和统计病例的相关值来评估益处。使用Campaign支付的媒体支出和相应的疫苗接种费用估算了成本。计算了净运动和疫苗接种效益和投资回报率。从2022年到2024年进行了分析。
    结果:在2021年4月至2022年3月之间,如果没有这项运动,估计将不会使用5590万剂COVID-19疫苗。运动疫苗接种导致轻度COVID-19病例减少2,576,133例,非致命性COVID-19住院人数减少243,979人,从COVID-19中拯救了51,675条生命。竞选总收益为7402亿美元,运动和疫苗接种费用总计83亿美元,净收益约为7320亿美元。每花1美元,这项运动和相应的疫苗接种费用带来了约89.54美元的收益.
    结论:我们可以做到的这项COVID-19公共教育活动挽救了5万多人的生命,防止了数十万人住院和数百万例COVID-19病例,在不到一年的时间里代表了数千亿美元的福利。研究结果表明,公共教育运动是降低COVID-19发病率和死亡率的一种具有成本效益的方法。
    This study estimated the benefits and costs of the U.S. Department of Health and Human Services\' We Can Do This COVID-19 public education campaign (the Campaign) and associated vaccination-related impacts.
    Weekly media market and national Campaign expenditures were used to estimate weekly first-dose vaccinations that would not have occurred absent the Campaign, weekly Campaign-attributed complete vaccinations, and corresponding COVID-19 cases, hospitalizations, and deaths averted. Benefits were valued using estimated morbidity and mortality reductions and associated values of a statistical life and a statistical case. Costs were estimated using Campaign paid media expenditures and corresponding vaccination costs. The net Campaign and vaccination benefit and return on investment were calculated. Analyses were conducted from 2022 to 2024.
    Between April 2021 and March 2022, an estimated 55.9 million doses of COVID-19 vaccines would not have been administered absent the Campaign. Campaign-attributed vaccinations resulted in 2,576,133 fewer mild COVID-19 cases, 243,979 fewer nonfatal COVID-19 hospitalizations, and 51,675 lives saved from COVID-19. The total Campaign benefit was $740.2 billion, and Campaign and vaccination costs totaled $8.3 billion, with net benefits of approximately $732.0 billion. For every $1 spent, the Campaign and corresponding vaccination costs resulted in benefits of approximately $89.54.
    The We Can Do This COVID-19 public education campaign saved more than 50,000 lives and prevented hundreds of thousands of hospitalizations and millions of COVID-19 cases, representing hundreds of billions of dollars in benefits in less than one year. Findings suggest that public education campaigns are a cost-effective approach to reducing COVID-19 morbidity and mortality.
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  • 文章类型: Journal Article
    背景:美国的孕产妇发病率和死亡率很高,而且还在不断增加,其中很大一部分与心血管健康(CVH)有关。方法:我们搜索了美国国立卫生研究院(NIH)支持的研究以及美国卫生与人类服务部(DHHS)其他两个机构在2016-2021财年的研究。补助金包括所有怀孕阶段的孕产妇健康状况或暴露,但不包括完全关注出生的补助金,新生儿,婴儿/儿童结局。通过审查抽象和具体目标来手动策划结果。被认为相关的赠款按类别分组。结果:2016-2021财年,孕产妇健康补助金总额保持不变,平均占DHHS补助金总额的1.4%。针对产妇CVH(MCVH)的755笔赠款为278,926,105美元,191,344,649美元是534个第一类赠款,代表了两倍的增长。非NIHDHHS机构最常资助与CVH相关的一般孕产妇健康;NIH重点资助被归类为妊娠期高血压疾病,产妇发病率和死亡率,肥胖,和糖尿病。非NIHDHSS机构最常资助的临床应用研究。除了临床应用补助金,NIH资助了大部分被归类为基础研究的赠款,临床试验,和/或翻译。国家之心,肺,和血液研究所(NHLBI)MCVH补助金研究参与者在产前期(78.5%),其次是产后(50.5%),孕前和围产期相对较少(10.8%和9.7%,分别);在NIH级别,围产期较好,为20.3%,而孕前时期仍然很低,为9.9%。结论:包括MCVH在内的孕产妇健康联邦拨款资金与总体研究资金的增长速度相同,仅占整体资金总额的1.4%。在整个NIH资助中,孕前时期没有得到充分研究,这是一个空白领域,资助机构可以进一步促进研究进展。
    Background: The United States has high and increasing rates of maternal morbidity and mortality, large proportions of which are related to cardiovascular health (CVH). Methods: We searched for National Institutes of Health (NIH) supported research as well as that of two other Agencies in the U.S. Department of Health and Human Services (DHHS) for fiscal years (FY) 2016-2021. Grants included maternal health conditions or exposures across all pregnancy stages, but excluded grants that focused entirely on birth, neonatal, infant/childhood outcomes. Results were manually curated by reviewing the abstract and specific aims. Grants deemed to be relevant were grouped by category. Results: Between FY 2016-2021, overall Maternal Health grants remained unchanged at an average of 1.4% of total DHHS grant funding. Maternal CVH-specific (MCVH) funding amounted to $278,926,105 for 755 grants, $191,344,649 was for 534 Type-1 grants, representing a twofold increase. Non-NIH DHHS agencies most commonly funded general Maternal Health related to CVH; NIH focused funding classified as hypertensive disorders of pregnancy, maternal morbidity and mortality, obesity, and diabetes. Non-NIH DHSS Agencies most commonly funded clinical applied research. In addition to clinical applied grants, NIH funded substantial proportions of grants classified as basic research, clinical trials, and/or translational. National Heart, Lung, and Blood Institute (NHLBI) MCVH grants studied participants in the pre-partum period (78.5%), followed by the post-partum period (50.5%), with relatively few in pre-pregnancy and peri-partum periods (10.8% and 9.7%, respectively); at the NIH level, the peri-partum period had better representation at 20.3%, whereas the pre-pregnancy period remained low at 9.9%. Conclusions: Federal grant funding for maternal health including MCVH increased at the same rate as its funding for overall research, and represented only 1.4% of overall total funding. The pre-pregnancy period was understudied in overall NIH funding and represents a gap area whereby funding agencies could further foster research advances.
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  • 文章类型: Journal Article
    虽然化学和放射性试剂通过不同的机制引起毒性,由这些威胁引起的多器官损伤在基本生物学反应水平上具有相似性。本出版物将讨论这些融合领域,并探索“多效用”方法,这些方法可用于以威胁不可知的方式解决化学和放射剂作用的共同损伤机制。此外,我们将概述放射性和化学威胁研究的现状,讨论美国政府在医疗准备方面的努力,并确定潜在的合作领域,以加强对放射性和化学威胁的准备和响应。我们还将讨论以前的监管经验,以提供有关如何为美国食品和药物管理局(FDA)批准/许可/清除产品解决化学或放射性/核威胁的监管路径的见解。本出版物是在2022年跨机构会议之后召开的,“皮肤和肺的辐射和硫芥末暴露中的重叠科学:模型的考虑,机制,器官系统,和医疗对策,由国家过敏和传染病研究所(NIAID)赞助,美国国立卫生研究院(NIH)的一部分。这次会议的讨论探讨了辐射和化学伤害的重叠性质,并激发了人们对一种威胁的准备如何导致另一种威胁的准备的兴趣。在这里,NIAID和生物医学高级研究与发展局(BARDA)的主题专家,战略准备和响应管理局(ASPR)的一部分,总结从最近资助的生物医学研究中获得的知识,以及2022年会议的见解。这些主题包括确定协作的共同领域,潜在使用损伤的生物标志物来识别由两种危害引起的损伤,以及可以治疗由放射性或化学威胁造成的损害的常见和广泛可用的治疗方法。
    Although chemical and radiological agents cause toxicity through different mechanisms, the multiorgan injuries caused by these threats share similarities that convene on the level of basic biological responses. This publication will discuss these areas of convergence and explore \"multi-utility\" approaches that could be leveraged to address common injury mechanisms underlying actions of chemical and radiological agents in a threat-agnostic manner. In addition, we will provide an overview of the current state of radiological and chemical threat research, discuss the US Government\'s efforts toward medical preparedness, and identify potential areas for collaboration geared toward enhancing preparedness and response against radiological and chemical threats. We also will discuss previous regulatory experience to provide insight on how to navigate regulatory paths for US Food and Drug Administration (FDA) approval/licensure/clearance for products addressing chemical or radiological/nuclear threats. This publication follows a 2022 trans-agency meeting titled, \"Overlapping Science in Radiation and Sulfur Mustard Exposures of Skin and Lung: Consideration of Models, Mechanisms, Organ Systems, and Medical Countermeasures,\" sponsored by the National Institute of Allergy and Infectious Diseases (NIAID), a part of the National Institutes of Health (NIH). Discussions from this meeting explored the overlapping nature of radiation and chemical injury and spurred increased interest in how preparedness for one threat leads to preparedness for the other. Herein, subject matter experts from the NIAID and the Biomedical Advanced Research and Development Authority (BARDA), a part of the Administration for Strategic Preparedness and Response (ASPR), summarize the knowledge gained from recently funded biomedical research, as well as insights from the 2022 meeting. These topics include identification of common areas for collaboration, potential use of biomarkers of injury to identify injuries caused by both hazards, and common and widely available treatments that could treat damage caused by radiological or chemical threats.
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    文章类型: Journal Article
    这次范围审查的目的是帮助那些想要使用调查数据的研究人员,在学术或社区环境中,为了识别和理解影响夏威夷原住民(NH)的健康差异,太平洋岛民(PI),和/或菲律宾人口,因为这些是已知和众多健康差异的群体。范围界定审查方法被用来识别调查数据集,这些数据集将数据分解为NH,PI,或者菲律宾人.搜索了Healthdata.gov,因为没有数据库的官方索引。该网站是由美国(US)部门和卫生与公共服务部门建立的,旨在增加企业家对健康数据的可访问性,研究人员,和政策制定者,最终目标是改善健康结果。使用搜索词\'调查,检索了332个数据集,其中许多是不同年份的复制品。包括符合以下标准的数据集:(1)与健康相关;(2)分类的NH,PI,和/或菲律宾亚组;(3)在美国管理;(4)公开提供;(5)个人水平的数据;(6)自我报告的信息;和(7)包含2010年或以后的数据。15个调查数据集符合纳入标准。同事们确定了另外两个调查数据集。对于每个数据集,数据集名称,数据源,多年的数据可用性,分类NH的可用性,PI,和/或菲律宾数据,关于健康结果和健康的社会决定因素的数据,并记录了网站信息。此数据集清单应用于希望进一步了解NH经历的健康差异的研究人员,PI,和美国的菲律宾人。
    The aim of this scoping review was to assist researchers who want to use survey data, either in academic or community settings, to identify and comprehend health disparities affecting Native Hawaiian (NH), Pacific Islander (PI), and/or Filipino populations, as these are groups with known and numerous health disparities. The scoping review methodology was used to identify survey datasets that disaggregate data for NH, PI, or Filipinos. Healthdata.gov was searched, as there is not an official index of databases. The website was established by the United States (US) Department and Health and Human Services to increase accessibility of health data for entrepreneurs, researchers, and policy makers, with the ultimate goal of improving health outcomes. Using the search term \'survey,\' 332 datasets were retrieved, many of which were duplicates from different years. Datasets were included that met the following criteria: (1) related to health; (2) disaggregated NH, PI, and/or Filipino subgroups; (3) administered in the US; (4) publicly available; (5) individual-level data; (6) self-reported information; and (7) contained data from 2010 or later. Fifteen survey datasets met the inclusion criteria. Two additional survey datasets were identified by colleagues. For each dataset, the dataset name, data source, years of the data availability, availability of disaggregated NH, PI, and/or Filipino data, data on health outcomes and social determinants of health, and website information were documented. This inventory of datasets should be of use to researchers who want to advance understanding of health disparities experienced by NH, PI, and Filipino populations in the US.
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  • 文章类型: Journal Article
    背景:美国有超过100万人死于COVID-19。为了应对这场公共卫生危机,美国卫生与公众服务部于2021年4月发起了“我们可以做到这一点”的公共教育运动,以提高对疫苗的信心。该活动使用了数字组合,电视,打印,广播和户外频道,以达到目标受众。然而,这项运动对疫苗接种的影响尚未评估.
    目的:我们的目标是通过评估“我们可以做到”COVID-19公共教育活动的数字印象与美国成年人首次接种COVID-19疫苗的可能性之间的关联来解决这一差距。
    方法:从美国概率小组招募的3,642名成年人的全国代表性样本进行了关于COVID-19疫苗接种的三波调查(W1:2021年1月至2月;W2:2021年5月至6月;W3:2021年9月至11月),疫苗信心,和社会人口统计学。在此期间,调查数据与每周向每个受访者的媒体市场(指定市场区域[DMA])发送的付费数字活动印象合并。分析单位是调查受访者广播周,受访者由DMA嵌套。使用多级logit模型分析数据,该模型具有DMA和时间固定效应的不同截距。
    结果:“我们可以做到”这项数字活动成功地鼓励了第一剂COVID-19疫苗接种。这些发现对多种建模规范都是稳健的,活动数字剂量变化的独立影响在所有模型中几乎保持不变。在给定的一周内,DMA级别的付费数字活动印象从30,000增加到30,000,使首次接种COVID19疫苗的可能性增加了125%。
    结论:这项研究的结果提供了初步证据,证明了我们可以做这项运动对疫苗摄取的数字影响。HHS的规模和长度,我们可以做这项公共教育活动,使其处于独特的位置,可以研究数字活动对COVID-19疫苗接种的影响,这可能有助于为未来的疫苗宣传工作和更广泛的公众教育工作提供信息。这些结果表明,Campaign数字剂量与美国成年人的COVID-19疫苗接种量呈正相关;建议未来研究评估Campaign对降低COVID-19归因于的发病率和死亡率以及其他益处的影响。这项研究表明,数字渠道在COVID-19大流行应对中发挥了重要作用。数字外联可能是应对未来大流行的组成部分,甚至可以在应对非大流行公共卫生危机中发挥作用。
    背景:
    Over 1 million people in the United States have died of COVID-19. In response to this public health crisis, the US Department of Health and Human Services launched the We Can Do This public education campaign in April 2021 to increase vaccine confidence. The campaign uses a mix of digital, television, print, radio, and out-of-home channels to reach target audiences. However, the impact of this campaign on vaccine uptake has not yet been assessed.
    We aimed to address this gap by assessing the association between the We Can Do This COVID-19 public education campaign\'s digital impressions and the likelihood of first-dose COVID-19 vaccination among US adults.
    A nationally representative sample of 3642 adults recruited from a US probability panel was surveyed over 3 waves (wave 1: January to February 2021; wave 2: May to June 2021; and wave 3: September to November 2021) regarding COVID-19 vaccination, vaccine confidence, and sociodemographics. Survey data were merged with weekly paid digital campaign impressions delivered to each respondent\'s media market (designated market area [DMA]) during that period. The unit of analysis was the survey respondent-broadcast week, with respondents nested by DMA. Data were analyzed using a multilevel logit model with varying intercepts by DMA and time-fixed effects.
    The We Can Do This digital campaign was successful in encouraging first-dose COVID-19 vaccination. The findings were robust to multiple modeling specifications, with the independent effect of the change in the campaign\'s digital dose remaining practically unchanged across all models. Increases in DMA-level paid digital campaign impressions in a given week from -30,000 to 30,000 increased the likelihood of first-dose COVID-19 vaccination by 125%.
    Results from this study provide initial evidence of the We Can Do This campaign\'s digital impact on vaccine uptake. The size and length of the Department of Health and Human Services We Can Do This public education campaign make it uniquely situated to examine the impact of a digital campaign on COVID-19 vaccination, which may help inform future vaccine communication efforts and broader public education efforts. These findings suggest that campaign digital dose is positively associated with COVID-19 vaccination uptake among US adults; future research assessing campaign impact on reduced COVID-19-attributed morbidity and mortality and other benefits is recommended. This study indicates that digital channels have played an important role in the COVID-19 pandemic response. Digital outreach may be integral in addressing future pandemics and could even play a role in addressing nonpandemic public health crises.
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  • 文章类型: Editorial
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  • 文章类型: Journal Article
    To protect both patients and staff, healthcare personnel (HCP) were among the first groups in the United States recommended to receive the COVID-19 vaccine. We analyzed data reported to the U.S. Department of Health and Human Services (HHS) Unified Hospital Data Surveillance System on COVID-19 vaccination coverage among hospital-based HCP. After vaccine introduction in December 2020, COVID-19 vaccine coverage rose steadily through April 2021, but the rate of uptake has since slowed; as of September 15, 2021, among 3,357,348 HCP in 2,086 hospitals included in this analysis, 70.0% were fully vaccinated. Additional efforts are needed to improve COVID-19 vaccine coverage among HCP.
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  • 文章类型: Journal Article
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  • 文章类型: Journal Article
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  • 文章类型: Journal Article
    在过去的几十年里,美国的性别薪酬差距已经缩小。美国女性/男性收入比从20世纪80年代前的约60%上升到2014年的约79%。然而,医护人员之间的性别薪酬差距仍然存在。这项研究的目的是估计2010-2018年美国联邦政府公共卫生人员的性别薪酬差距。
    我们使用了一个管理数据集,其中包括美国卫生与公共服务部员工的年薪率和工作特征。员工的性别是根据名字分类的。回归分析用于使用预测的性别来估计性别工资差距。
    DHHS的女性雇员在2010年的收入比男性低约13%,在2018年低9.2%。职业,薪酬计划,和地点解释了一半以上的性别工资差距。控制工作等级进一步减少差距。2018年性别工资差距的无法解释部分在1.0%至3.5%之间。在研究期间,女性雇员在加薪方面略有优势。
    虽然性别工资差距在过去的二十年里缩小了,联邦政府公共卫生工作人员中男女雇员之间的薪酬差距仍然存在,值得继续关注和研究。应继续努力缩小卫生工作人员之间的性别工资差距。
    The gender pay gap in the United States (US) has narrowed over the last several decades, with the female/male earnings ratio in the US increased from about 60% before the 1980s to about 79% by 2014. However, the gender pay gap among the healthcare workforce persists. The objective of this study is to estimate the gender pay gap in the US federal governmental public health workforce during 2010-2018.
    We used an administrative dataset including annual pay rates and job characteristics of employees of the US Department of Health and Human Services. Employees\' gender was classified based on first names. Regression analyses were used to estimate the gender pay gap using the predicted gender.
    Female employees of the DHHS earned about 13% less than men in 2010, and 9.2% less in 2018. Occupation, pay plan, and location explained more than half of the gender pay gap. Controlling for job grade further reduces the gap. The unexplained portion of the gender pay gap in 2018 was between 1.0 and 3.5%. Female employees had a slight advantage in terms of pay increase over the study period.
    While the gender pay gap has narrowed within the last two decades, the pay gap between female and male employees in the federal governmental public health workforce persists and warrants continuing attention and research. Continued efforts should be implemented to reduce the gender pay gap among the health workforce.
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