Three-dimensional analysis

三维分析
  • 文章类型: Case Reports
    现在,增强植入物周围软硬组织结构的重要性已被广泛接受。然而,虽然大多数当代研究都支持这个前提,临床医生遇到种植体周围软组织缺损的频率越来越高,因此,他们需要重建。这些并发症可能是由于难以建立适当的诊断和治疗计划或不良的临床情况(植入物错位,前庭牙槽骨厚度不足或粘膜厚度不足)。在这种情况下,种植体周围软组织表型在短期和长期对美学和健康相关结果的影响最大。本文介绍了两个临床病例,其中提出了对根尖通道技术的修改,这可能在需要粘膜厚度大幅增加的临床情况下有用。使用改良的双层根尖通道和去上皮化的游离牙龈移植技术显示出有希望的结果,粘膜厚度显着增加,美学和种植体周围健康的结果令人满意。
    The importance of augmenting the peri-implant soft- and hard-tissue architecture is now widely accepted. However, while most contemporary research supports this premise, clinicians are encountering peri-implant soft tissue defects with increasing frequency, which they are therefore required to reconstruct. These complications can result from the difficulty of establishing an appropriate diagnosis and treatment plan or from suboptimal clinical situations (implant malposition, insufficient vestibular alveolar bone thickness or inadequate mucosal thickness). In this context, it is the peri-implant soft-tissue phenotype that most influences esthetic and health-related results in the short and long term. This article describes two clinical cases in which a modification of the apical access technique is presented that may be useful in clinical scenarios requiring large gains in mucosal thickness. Use of the modified bilaminar apical access with de-epithelialized free gingival graft technique showed promising results, with a significant increase in mucosal thickness and satisfactory outcomes in esthetics and peri-implant health.
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  • 文章类型: Journal Article
    关于上颌窦增强术中植骨的确切数量尚未达成共识。这项研究的目的是估计增加鼻窦的最小骨体积,并研究影响增加体积(AV)的因素。
    这项研究包括接受锥形束计算机断层扫描的患者。在A组(未植入)和B组(植入)中,在3、5、7和9mm的垂直高度(VH)几乎进行了圆顶形窦增强。测量增大角(AA)和窦宽度(SW)。使用三维图像处理程序3DSlicer测量AV。进行单变量和多变量分析。
    本研究包括30名患者(120名受试者)。A组,在3、5、7和9mm的VHs下,平均AVs分别为0.062、0.271、0.642和1.287cc,分别,B组,平均AVs分别为0.037,0.230,0.594和1.230cc.单变量分析显示两组与房室病变显著相关的因素包括SW,AA,和VH(P<0.001)。多因素分析显示,与AV相关的因素包括AA和VH(P<0.01)。
    临床医生可以通过测量增加高度和角度来预测用于鼻窦增加的骨体积。
    UNASSIGNED: No consensus has been established regarding the exact amount of bone grafting in maxillary sinus augmentation. The aim of this study was to estimate the minimum bone volume for sinus augmentation and to investigate the factors that influence the augmentation volume (AV).
    UNASSIGNED: This study included patients with cone-beam computed tomography scanning. Dome-shaped sinus augmentation was performed virtually at vertical heights (VH) of 3, 5, 7, and 9 mm in Group A (without implantation) and Group B (with implantation). The augmentation angle (AA) and the sinus width (SW) were measured. The AV was measured using the three-dimensional image processing program 3D Slicer. Univariable and multivariable analyses were conducted.
    UNASSIGNED: This study included 30 patients (120 subjects). In Group A, the mean AVs were 0.062, 0.271, 0.642, and 1.287 cc at VHs of 3, 5, 7, and 9 mm, respectively, in Group B, the mean AVs were 0.037, 0.230, 0.594, and 1.230 cc. Univariable analysis indicated that factors significantly associated with the AV in both groups included SW, AA, and VH (P < 0.001). Multivariable analysis indicated that factors significantly associated with the AV in both groups included AA and VH (P < 0.01).
    UNASSIGNED: Clinicians can predict the bone volume for sinus augmentation by measuring the augmentation height and angle.
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  • 文章类型: Journal Article
    本研究旨在探讨颞下颌关节(TMJ)积液与TMJ疼痛之间的关系,以及通过二维(2D)和三维(3D)磁共振成像(MRI)评估患者的颌骨功能限制。
    121例被诊断为颞下颌关节紊乱病(TMD)的患者被纳入。使用MRI定性评估TMJ积液,并使用3DSlicer软件定量。然后相应地分级。此外,采用视觉模拟量表(VAS)进行疼痛报告,采用8项颌骨功能限制量表(JFLS-8)评估颌骨功能限制.适当地进行统计分析以进行组比较和关联确定。P<0.05的概率被认为是统计学上显著的。
    2D定性和3D定量策略对于TMJ积液等级(κ=0.766)是高度一致的。关节积液与颞下颌关节疼痛无显著关联,也没有椎间盘位移和JLFS-8评分。此外,二元logistic回归分析显示性别与TMJ积液的存在显著相关,女性的赔率为5.168(p=0.008)。
    2D定性评估与3D定量评估对TMJ积液的诊断同样有效。在TMJ积液和TMJ疼痛之间没有发现显着关联。椎间盘位移或钳口功能限制。然而,研究表明,女性TMD患者可能存在TMJ积液的风险.需要进一步的前瞻性研究进行验证。
    UNASSIGNED: This study aimed to investigate the relationship between temporomandibular joint (TMJ) effusion and TMJ pain, as well as jaw function limitation in patients via two-dimensional (2D) and three-dimensional (3D) magnetic resonance imaging (MRI) evaluation.
    UNASSIGNED: 121 patients diagnosed with temporomandibular disorder (TMD) were included. TMJ effusion was assessed qualitatively using MRI and quantified with 3D Slicer software, then graded accordingly. In addition, a visual analogue scale (VAS) was employed for pain reporting and an 8-item Jaw Functional Limitations Scale (JFLS-8) was utilized to evaluate jaw function limitation. Statistical analyses were performed appropriately for group comparisons and association determination. A probability of p<0.05 was considered statistically significant.
    UNASSIGNED: 2D qualitative and 3D quantitative strategies were in high agreement for TMJ effusion grades (κ = 0.766). No significant associations were found between joint effusion and TMJ pain, nor with disc displacement and JLFS-8 scores. Moreover, the binary logistic regression analysis showed significant association between sex and the presence of TMJ effusion, exhibiting an Odds Ratio of 5.168 for females (p = 0.008).
    UNASSIGNED: 2D qualitative evaluation was as effective as 3D quantitative assessment for TMJ effusion diagnosis. No significant associations were found between TMJ effusion and TMJ pain, disc displacement or jaw function limitation. However, it was suggested that female patients suffering from TMD may be at a risk for TMJ effusion. Further prospective research is needed for validation.
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  • 文章类型: Journal Article
    背景:牙源性上颌窦炎(OMS)在牙科和耳鼻咽喉科领域都得到了广泛认可。最近,医源性牙源性上颌窦炎可以经常遇到。这项研究的目的是通过比较CBCT和症状的术前和术后体积测量,评估使用小侧窗入路对牙源性上颌窦炎患者进行口内冲洗的效果。我们调查了2016年至2022年在PNUDH口腔颌面外科就诊的21例患者。所有患者的信息都是从电子数据库中提取的。包括随访时间为2个月或更长时间的患者。使用ImageJ程序(美国国立卫生研究院,威斯康星大学)。
    结果:在21例患者中,16人(76.1%)为男性,5名(23%)为女性。最常见的手术类型是全身麻醉(16例),其中7例有口窦瘘。在上颌窦炎的原因中,有七名植入物相关患者,五名拔牙患者,7名植骨患者,和其他组的两名患者。鼻窦冲洗后,射线照相不透明度降低了40.15%,尤其是在植骨和拔牙病例中。临床上,17例(80.9%)患者症状得到改善。
    结论:通过这项研究,可以得出结论,小侧窗入路上颌窦冲洗是临床和放射学上有效的治疗牙源性上颌窦炎的方法。
    BACKGROUND: Odontogenic maxillary sinusitis (OMS) is widely acknowledged in both the dentistry and otolaryngology fields. Recently, iatrogenic odontogenic maxillary sinusitis cases can be encountered frequently. The purpose of this study was to evaluate the effect of intraoral sinus irrigation using the small lateral window approach in patients with odontogenic maxillary sinusitis by comparing pre- and postoperative volumetric measurement of CBCT and symptoms. We surveyed 21 patients who visited the Oral and Maxillofacial Surgery Department at PNUDH from 2016 to 2022. All the patients\' information was extracted from an electronic database. The patients with a follow-up period of 2 months or more were included. The three-dimensional volumetric measurement was performed using the ImageJ program (National Institute of Health, University of Wisconsin).
    RESULTS: Among 21 patients, 16 (76.1%) were male, and 5 (23%) were female. The most common type of surgery was general anesthesia (16 cases) in which oroantral fistula was present in 7 cases. In the causes of maxillary sinusitis, there were seven implant-related patients, five patients of tooth extraction, seven patients of bone grafting, and two patients in other groups. Radiographic opacity decreased by 40.15% after sinus irrigation especially in bone graft and tooth extraction cases. Clinically, symptoms improved in 17 patients (80.9%).
    CONCLUSIONS: By this study, it can be concluded that maxillary sinus irrigation using the small lateral window approach is a clinically and radiologically effective treatment method for odontogenic maxillary sinusitis.
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  • 文章类型: Journal Article
    尺尺关节(DRUJ)损伤可能是毁灭性的,并且具有挑战性。尺骨表现出的多平面曲率影响DRUJ的形态,这使得很难单独通过二维射线照片进行评估。我们用了全长,三维(3D)计算机断层扫描血管造影扫描,以评估尺骨弯曲之间的关系,DRUJ尺骨方差(UV),和乙状结肠缺口角。这项研究的目的是建立这些标志的正常解剖范围,以改善前臂创伤和DRUJ病理的治疗。
    检查了82次完整的上肢计算机断层扫描血管造影扫描并重建为3D模型。我们使用计算机辅助设计软件对尺骨弯曲和DRUJ指标进行了表征。计算集中趋势和皮尔逊相关系数的度量进行比较分析。
    该研究得出272.3mm的平均尺骨长度。我们确定近端尺骨弓占骨骼总长度的36.7%,深度为10.3毫米,6.6°的近端角度,和3.9°的远端角度。尺骨远端弓出现在骨长度的75.3%处,以4.2毫米的深度为特征,2°的近端角度,和4.3°的远端角度。在日冕平面上,尺弓近端角度与紫外线呈正相关(r=0.39,P<.001),而远端尺骨弓的远角呈负相关(r=-0.48,P<.001)。我们还发现近端和远端弓的深度与紫外线之间存在显着相关性(分别为r=0.38,P<.001;r=-0.34,P<.001)。此外,DRUJ内的紫外线与S形切口角密切相关(r=-0.77,P=0.01)。相比之下,矢状平面指标与紫外线没有显示有意义的相关性.
    DRUJ关节处的矢状对齐和平移与尺骨远端的尺骨弯曲直接相关。对这些3D关系的细微了解可以在纠正尺侧病理时增强术前计划。
    治疗IV。
    UNASSIGNED: Distal radioulnar joint (DRUJ) injuries can be devastating and challenging to manage. The multiplanar curvature exhibited by the ulna impacts the morphology of the DRUJ, making it difficult to assess through two-dimensional radiographs alone. We used full-length, three-dimensional (3D) computed tomography angiography scans to assess the relationship between ulnar bowing, DRUJ ulnar variance (UV), and sigmoid notch angle. The goal of this study was to establish normal anatomic ranges for these landmarks to improve treatment for forearm traumas and DRUJ pathologies.
    UNASSIGNED: Eighty-two intact upper extremity computed tomography angiography scans were examined and reconstructed into 3D models. We characterized ulnar bowing and DRUJ metrics using computer-aided design software. Measures of central tendency and Pearson correlation coefficients were calculated for comparative analysis.
    UNASSIGNED: The study yielded an average ulnar length of 272.3 mm. We identified the proximal ulnar bow at 36.7% of the bone\'s total length, possessing a depth of 10.3 mm, a proximal angle of 6.6°, and a distal angle of 3.9°. The distal ulnar bow appeared at 75.3% of the bone\'s length, characterized by a depth of 4.2 mm, a proximal angle of 2°, and a distal angle of 4.3°. In the coronal plane, the proximal angle of the proximal ulnar bow correlated positively with UV (r = 0.39, P < .001), whereas the distal angle of the distal ulnar bow correlated negatively (r = -0.48, P < .001). We also found significant correlations between the depths of both proximal and distal bows with UV (r = 0.38, P < .001; r = -0.34, P < .001, respectively). Moreover, UV within the DRUJ strongly correlated with the sigmoid notch angle (r = -0.77, P = .01). In contrast, the sagittal plane metrics did not show meaningful correlations with UV.
    UNASSIGNED: Sagittal alignment and translation at the DRUJ articulation are directly related to ulna bowing at the distal ulna. A nuanced understanding of these 3D relationships can enhance preoperative planning when correcting ulnar-side pathology.
    UNASSIGNED: Therapeutic IV.
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  • 文章类型: Journal Article
    目的:小儿肱骨髁上骨折(PSHFs)后肘内翻畸形(CVD)的三维(3D)重塑能力仍未阐明。这项研究通过检查受伤后随时间的3D畸形分布来调查PSHFs后的重塑模式。
    方法:分析86例PSHFs后CVD患者的计算机断层扫描(CT)数据。三维畸形角度在矢状,日冕,评估和轴向方向,并与受伤年龄和CT评估之间的持续时间相关。对于子群分析,我们在年轻组(<8岁)和老年组(≥8岁)中进行了相同的相关性分析;我们将持续时间分为早期(<2年),中期(≥2至<5年),和晚期(≥5年),并比较三组各方向的畸形角度。
    结果:矢状畸形与畸形持续时间呈中度相关(r=-0.54;P<0.001),而冠状和轴向畸形显示出微不足道的相关性。年轻组矢状畸形与病程呈中度相关(r=-0.62;P<0.001),老年组则呈弱相关(r=-0.37;P=0.091)。在矢状方向上,早期畸形角度明显大于中晚期(P<0.001)。然而,三组之间在冠状方向和轴向方向上没有显着差异。
    结论:CVD的矢状畸形能够重塑,尤其是在早期和年轻的时候,而冠状和轴向畸形不太可能进行重塑。
    OBJECTIVE: Three-dimensional (3D) capacity for remodelling in cubitus varus deformity (CVD) after paediatric supracondylar humeral fractures (PSHFs) remains unelucidated. This study investigated remodelling patterns after PSHFs by examining 3D deformity distribution over time after injury.
    METHODS: Computed tomography (CT) data of 86 patients with CVD after PSHFs were analysed. The 3D deformity angles in the sagittal, coronal, and axial directions were assessed and correlated with the duration between the age at injury and CT evaluation. For the subgroup analysis, we performed the same correlation analysis in a younger (< 8 years old) and an older group (≥ 8 years old); we categorized the duration into early (< 2 years), middle (≥ 2 to < 5 years), and late periods (≥ 5 years) and compared the deformity angles of each direction among the three groups.
    RESULTS: Sagittal deformity showed a moderate correlation with the duration of deformity (r = -0.54; P < 0.001), while coronal and axial deformities showed a negligible correlation. Sagittal deformity showed moderate correlations with the duration in the younger group (r = -0.62; P < 0.001) and weak correlations in the older group (r = -0.37; P = 0.091). In the sagittal direction, the deformity angle in the early period was significantly larger than those in the mid and late periods (P < 0.001). However, there were no significant differences among the three groups in the coronal and axial directions.
    CONCLUSIONS: Sagittal deformities in CVDs are capable of remodelling, especially in the early period and at a younger age, whereas coronal and axial deformities are less likely to undergo remodelling.
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  • 文章类型: Journal Article
    男性不育是所有不育病例中大约一半的重要因素,其特征是精子数量和运动能力下降。精子数量减少不仅是由于精子产量减少,而且成功通过男性生殖道的数量减少。平滑肌运动可能在男性生殖道的精子运输中起重要作用;因此,了解这种运动的机制对于阐明精子运输障碍的原因是必要的。最近的研究强调了各种平滑肌器官中血小板衍生的生长因子受体α(PDGFRα)阳性间质细胞(PIC)的存在。虽然研究还在进行中,男性生殖道中的PICs可能参与平滑肌运动的调节,就像它们在其他平滑肌器官中一样。这篇综述总结了迄今为止关于男性生殖器官中PIC的发现。结构的进一步探索,功能,和PICs的分子特征可以为男性不育的发病机制提供有价值的见解,并可能导致新的治疗方法。
    Male infertility is a significant factor in approximately half of all infertility cases and is marked by a decreased sperm count and motility. A decreased sperm count is caused by not only a decreased production of sperm but also decreased numbers successfully passing through the male reproductive tract. Smooth muscle movement may play an important role in sperm transport in the male reproductive tract; thus, understanding the mechanism of this movement is necessary to elucidate the cause of sperm transport disorder. Recent studies have highlighted the presence of platelet-derived growth factor receptor α (PDGFRα)-positive interstitial cells (PICs) in various smooth muscle organs. Although research is ongoing, PICs in the male reproductive tract may be involved in the regulation of smooth muscle movement, as they are in other smooth muscle organs. This review summarizes the findings to date on PICs in male reproductive organs. Further exploration of the structural, functional, and molecular characteristics of PICs could provide valuable insights into the pathogenesis of male infertility and potentially lead to new therapeutic approaches.
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  • 文章类型: Journal Article
    背景:在股骨头坏死(ONFH)的经转子旋转截骨术(TRO)失败后的全髋关节置换术(THA)中,据报道,股骨近端畸形会影响茎的放置。这项研究的目的是评估股骨近端的形态学变化,肌肉萎缩,THA术后软组织增厚及临床转归。
    方法:TRO组包括在TRO失败后接受THA的17例患者(18髋)。对照组包括21例(28髋)接受原发性THA治疗的ONFH患者。为了在THA之前评估股骨近端畸形,我们在小转子近端5mm的计算机断层扫描切片上测量了股骨的前后和中外侧直径。评估肌肉萎缩和软组织增厚,我们测量了腰大肌的厚度,髂关节,臀中肌和髋关节前囊.
    结果:TRO组股骨近端前后径与中外侧径之比明显更大(p<0.01)。两组之间的肌肉厚度没有差异,而TRO组前囊明显增厚(p<0.05)。TRO组常见内翻或外翻茎排列(>3°)(p<0.01)。
    结论:与ONFH的原发性THA相比,TRO后股骨近端圆形变形,这可能导致了茎的错位。此外,我们应该注意股骨近端前突和前囊增厚。
    BACKGROUND: In total hip arthroplasty (THA) after failed transtrochanteric rotational osteotomy (TRO) for osteonecrosis of the femoral head (ONFH), deformity of the proximal femur has been reported to affect stem placement. The aims of this study were to evaluate the morphological changes in the proximal femur, muscle atrophy, and soft tissue thickening in THA after TRO and the clinical outcomes.
    METHODS: The TRO group included 17 patients (18 hips) who underwent THA after failed TRO. The control group included 21 patients (28 hips) who underwent primary THA for ONFH. To evaluate the deformity of the proximal femur before THA, we measured the anteroposterior and mediolateral diameters of the femur on computed tomographic slices 5 mm proximal to the lesser trochanter. To evaluate muscle atrophy and soft tissue thickening, we measured the thicknesses of the psoas major, iliac, and gluteus medius muscles and the anterior capsule of the hip joint.
    RESULTS: The ratio of the anteroposterior to mediolateral diameters of the proximal femur was significantly greater in the TRO group (p < 0.01). The thicknesses of the muscles did not differ between the two groups, whereas the anterior capsule was significantly thicker in the TRO group (p < 0.05). Varus or valgus stem alignment (> 3°) was frequent in the TRO group (p < 0.01).
    CONCLUSIONS: The round shape of the proximal femur was deformed after TRO compared with primary THA for ONFH, which may have caused malposition of the stem. In addition, we should pay attention to anterior protrusion of the proximal femur and thickening of the anterior capsule.
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  • 文章类型: Journal Article
    其领先的髋部内旋(IR)的运动范围(ROM)减小的高尔夫球手的腰部旋转ROM和负荷增加。这项研究调查了在高尔夫挥杆过程中,泡沫辊(FR)应用于其主要臀部肌肉,并拉伸到主要臀部以及腰椎旋转ROM的效果。研究设计是交叉设计。受试者被分配到包括FR和动态伸展(FR+DS)或练习摆动的两组中的一组。运动分析用于评估高尔夫挥杆过程中的臀部和腰部角度。使用方差分析和Bonferroni校正,使用配对t检验的事后比较数据。使用相关分析研究了铅髋部IR角与腰椎左旋转(Lrot)角之间的关联。FR+DS组高尔夫挥杆过程中的铅髋部IRROM显著更大(p=0.034)。FR+DS组在高尔夫挥杆过程中显示铅髋部IRROM和下腰椎LrotROM之间呈中度负相关(r=-0.522)。FR+DS的应用可能有助于在高尔夫挥杆过程中增加铅髋部IR角。此外,FR+DS的应用可改善髋部导联IR角度,并可减少腰椎旋转。
    Golfers with decreased range of motion (ROM) of their leading hip internal rotation (IR) have increased lumbar rotation ROM and load. This study investigated the effects of foam roller (FR) applied to their leading hip muscles combined with stretching to the leading hip together with lumbar rotation ROM during the golf swing. The study design was a crossover design. Subjects were allocated to one of two groups comprising FR and dynamic stretching (FR + DS) or practice swing. Motion analysis was used to evaluate hip and lumbar angles during the golf swing. Data were compared using analysis of variance with Bonferroni correction using paired t-test\'s post hoc. The association between lead hip IR angle and lumbar spine left rotation (Lrot) angle was investigated using correlation analysis. Lead hip IR ROM during the golf swing was significantly greater in the FR + DS group (p = 0.034). The FR + DS group showed a moderate negative correlation between lead hip IR ROM and lower lumbar spine Lrot ROM during the golf swing (r = -0.522). The application of FR + DS might be useful to increase lead hip IR angle during the golf swing. Moreover, the application of FR + DS improves lead hip IR angle and may decrease lumbar spine rotation.
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  • 文章类型: Randomized Controlled Trial
    背景:新兴的临床数据指出了角质化组织(KT)的存在的相关性。尽管顶部定位的皮瓣/前庭成形术以及游离牙龈移植物(FGG)被认为是增加KT的标准干预措施,替代材料似乎是一种可行的治疗方法。到目前为止,缺乏调查用软组织替代物或FGG治疗的植入部位尺寸变化的数据.
    目的:本研究旨在比较猪来源的胶原基质(CM)和FGG在6个月随访期间增加牙种植体KT的三维变化。
    方法:该研究招募了32名表现出KT宽度不足的患者(即<2mm)在前庭方面使用CM(15名患者/23个植入物)或FGG(17名患者/31个植入物)进行软组织增强。主要结果定义为1-(S0)之间治疗植入部位的组织厚度变化(mm),3-(S1),6个月(S2)。次要结果考虑了6个月随访期间KT宽度的变化,手术治疗时间,和患者报告的结果。
    结果:从S0到S1和从S0到S2的尺寸分析显示,CM组的组织厚度平均减少-0.14±0.27mm和-0.04±0.40mm,FGG组的-0.08±0.29mm和-0.13±0.23mm,两组之间没有显着差异(3个月:p=0.542,6个月:p=0.659)。同样,在两组中,从S1到S2观察到相当的组织厚度下降(CM:-0.03±0.22mm,FGG:-0.06±0.14mm;p=0.467)。与CM组相比,FGG组在1、3和6个月后表现出明显更大的KT增益(1个月:CM:3.66±1.67mm,FGG:5.90±1.58mm;p=0.002;3个月:CM:2.22±1.44;FGG:4.91±1.55;p=0.0457;6个月:CM:1.45±1.13mm,FGG:4.52±1.40mm;p<0.1)。手术时间(CM:23.33±7.04分钟。;FGG:39.25±10.64分钟。;p=0.001),CM组术后镇痛药的摄入量显着降低(CM:1.2±1.08片;FGG:5.64±6.39片;p=0.001)。
    结论:CM和FGG在1至6个月之间具有相当的三维厚度变化。虽然可以使用FGG建立更宽的KT频段,CM的使用显着减少了手术时间和患者的镇痛药摄入量。
    BACKGROUND: Emerging clinical data points to the relevance of the presence of keratinized tissue (KT). Although apically positioned flap/vestibuloplasty along with free gingival graft (FGG) is considered as a standard intervention for augmenting KT, substitute materials appear to be a viable treatment alternative. So far, there is a lack of data investigating the dimensional changes at implant sites treated with soft-tissue substitutes or FGG.
    OBJECTIVE: The present study aimed at comparing three-dimensional changes of a porcine derived collagen matrix (CM) and FGG for increasing KT at dental implants over a 6-month follow-up period.
    METHODS: The study enrolled 32 patients exhibiting deficient KT width (i.e., < 2 mm) at the vestibular aspect who underwent soft tissue augmentation using either CM (15 patients/23 implants) or FGG (17 patients/31 implants). The primary outcome was defined as tissue thickness change (mm) at treated implant sites between 1- (S0), 3- (S1), and 6-months (S2). Secondary outcomes considered changes of KT width over a 6-month follow-up period, surgical treatment time, and patient-reported outcomes.
    RESULTS: Dimensional analyses from S0 to S1 and from S0 to S2 revealed a mean decrease in tissue thickness of - 0.14 ± 0.27 mm and - 0.04 ± 0.40 mm in the CM group, and - 0.08 ± 0.29 mm and - 0.13 ± 0.23 mm in the FGG group, with no significant differences noted between the groups (3 months: p = 0.542, 6 months: p = 0.659). Likewise, a comparable tissue thickness decrease was observed from S1 to S2 in both groups (CM: - 0.03 ± 0.22 mm, FGG: - 0.06 ± 0.14 mm; p = 0.467). The FGG group exhibited a significantly greater KT gain after 1, 3 and 6 months compared to the CM group (1 month: CM: 3.66 ± 1.67 mm, FGG: 5.90 ± 1.58 mm; p = 0.002; 3 months: CM: 2.22 ± 1.44; FGG: 4.91 ± 1.55; p = 0.0457; 6 months: CM: 1.45 ± 1.13 mm, FGG: 4.52 ± 1.40 mm; p < 0.1). Surgery time (CM: 23.33 ± 7.04 min.; FGG: 39.25 ± 10.64 min.; p = 0.001) and postoperative intake of analgesics were significantly lower in the CM group (CM: 1.2 ± 1.08 tablets; FGG: 5.64 ± 6.39 tablets; p = 0.001).
    CONCLUSIONS: CM and FGG were associated with comparable three-dimensional thickness changes between 1 and 6 months. While a wider KT band could be established with FGG, the use of CM significantly reduced surgical time and patients´ intake of analgesics.
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