Shock wave lithotripsy

冲击波碎石术
  • 文章类型: Journal Article
    所有临床冲击波碎石机都会产生轴对称声场,而不会考虑患者肾脏的解剖特征或呼吸运动。这项工作提出了一种可操纵和可调的聚焦电液(SAFE)冲击波发生器设计,具有可变的光束尺寸和形状。
    90个电液换能器同心安装在球形盆上,与单个换能器的连接可调。每个换能器由45个嵌入环氧树脂的3D打印钛微电极组成,尖端直径为0.3mm。所有的换能器被布置在5个同心环中并且被细分为6个扇区。
    通过改变各个传感器的连接,由换能器阵列产生的聚焦压力场可以是轴对称的,直径为14.8mm的-6dB焦距,或非轴对称,长轴为22.7毫米,短轴为15.1毫米。细长梁产生的峰值正压力为33.7±4.1MPa,粉碎效率为42.2±3.5%,与20kV下150个脉冲后的轴对称梁的36.2±0.7MPa和28.6±6.1%相比。
    我们已经证明,SAFE冲击波发生器可以产生细长的非轴对称压力场,并具有更高的石头粉碎效率。SAFE冲击波发生器可以提供灵活和通用的设计,以实现准确,稳定,和安全的碎石治疗肾结石。
    UNASSIGNED: All clinical shock wave lithotripters produce an axisymmetric acoustic field without accounting for the anatomic features of the kidney or respiratory motion of the patient. This work presents a steerable and adjustable focusing electrohydraulic (SAFE) shock wave generator design with variable beam size and shape.
    UNASSIGNED: 90 electrohydraulic transducers are mounted concentrically on a spherical basin with adjustable connection to individual transducers. Each transducer consists of 45 3D-printed titanium microelectrodes embedded in epoxy with a tip diameter of 0.3 mm. All the transducers are arranged in 5 concentric rings and sub-divided into 6 sectors.
    UNASSIGNED: By changing the connections of individual transducers, the focused pressure field produced by the transducer array can be either axisymmetric with a -6 dB focal width of 14.8 mm in diameter, or non-axisymmetric with a long axis of 22.7 mm and a short axis of 15.1 mm. The elongated beam produces a peak positive pressure of 33.7±4.1 MPa and comminution efficiency of 42.2±3.5%, compared to 36.2±0.7 MPa and 28.6±6.1% for axisymmetric beam after 150 pulses at 20 kV.
    UNASSIGNED: We have demonstrated that the SAFE shock wave generator can produce an elongated non-axisymmetric pressure field with higher stone comminution efficiency. The SAFE shock wave generator may provide a flexible and versatile design to achieve accurate, stable, and safe lithotripsy for kidney stone treatment.
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  • 文章类型: Review
    体外冲击波碎石术(ESWL)是一种安全有效的泌尿系结石疾病治疗方法。总体无石率(SFR)差异显著。这项研究旨在评估石头大小的影响,location,石材密度,和皮肤到石头的距离(SSD),关于ESWL的结果。我们评估了与仅肾输尿管膀胱膜(KUB)相比,治疗前非对比增强CT扫描(NCCT)是否具有显着优势。我们回顾了307例(165例男性,142名妇女)患有肾和输尿管结石,在2020年至2023年期间在我们的机构接受ESWL连续治疗。其中44人接受了NCCT。ESWL的结果以两种方式定义:KUB上可见的结石碎片,以及进一步治疗的需要。碎片的总体成功率为85%(261名患者)。61%的患者(n=184)不需要任何进一步的治疗。结石大小和位置与需要进一步治疗(p=0.004)和结石碎片(p=0.016)的治疗结果显着相关,分别。与平均SSD(p=0.462)不同,平均衰减值(MAV)与是否需要再治疗显著相关(p=0.016).MAV似乎是治疗成功的更好预测指标(ROC曲线的AUC:0.729),与结石大小相比(AUC:0.613)。两组(有和没有NCCT)在两种治疗结果中的差异均未达到统计学意义。在决策过程中,有关SSD和MAV的信息在更可疑的情况下可能很有用。然而,与仅仅依靠KUB相比,它们的加入似乎没有提供实质性的优势。
    Extracorporeal shock wave lithotripsy (ESWL) is a safe and efficient treatment option for urinary stone disease. The overall stone-free rate (SFR) varies significantly. This study aimed to assess the influence of stone size, location, stone density, and skin-to-stone distance (SSD), on the outcome of ESWL. We assessed whether pre-treatment non-contrast-enhanced CT scan (NCCT) confers significant advantages compared to kidney-ureter-bladder film (KUB) only. We reviewed the medical records of 307 cases (165 men, 142 women) with renal and ureteral stones treated consecutively at our institution with ESWL between 2020 and 2023. 44 of these underwent a NCCT. The outcome of ESWL was defined in two ways: visible stone fragmentation on KUB, and the need for further treatment. Overall success of fragmentation was 85% (261 patients). 61% of patients (n = 184) didn\'t need any further treatment. Stone size and location correlated significantly with treatment outcomes regarding the need for further treatment (p = 0.004) and stone fragmentation (p = 0.016), respectively. Unlike mean SSD (p = 0.462), the mean attenuation value (MAV) significantly correlated with the need for retreatment (p = 0.016). MAV seems to be a better predictor of treatment success (AUC of the ROC curve: 0.729), compared to stone size (AUC: 0.613). The difference between groups (with and without NCCT) in both treatment outcomes did not reach statistical significance. During decision-making, information regarding SSD and MAV can be useful in more dubious scenarios. However, it appears that their inclusion doesn\'t provide substantial advantages when compared to relying solely on KUB.
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  • 文章类型: Journal Article
    UNASSIGNED: In this review, we investigated the current literature to find out which artificial stones (AS) are available in endourology, and in which experimental and training schemes they are used.
    UNASSIGNED: A systematic review was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement. Twenty-one out of 346 studies met our inclusion criteria and are presented in the current review. The inclusion criteria were the existence of AS and their use for laboratory and training studies.
    UNASSIGNED: There is a wide variety of materials used for the creation of AS. BegoStone powder (BEGO USA, Lincoln, Rhode Island) and plaster of Paris™ were used in most of the studies. In addition, Ultracal-30 (U. S. Gypsum, Chicago, IL) was also used. Other materials that were used as phantoms were AS created from plaster (Limbs and Things, UK), standardized artificial polygonal stone material (Chaton 1028, PP13, Jet 280; Swarovski), model stones consisting of spheres of activated aluminum (BASF SE, Ludwigshafen am Rhein, Deutschland), Orthoprint (Zhermack, Badia Polesine, Italy), and a combination of plaster of Paris, Portland cement, and Velmix (calcium sulfate powder). Many experimental settings have been conducted with the use of AS. Our research demonstrated nine studies regarding testing and comparison of holmium: yttrium-aluminum-garnet laser devices, techniques, and settings. Six studies were about extracorporeal shock wave lithotripsy testing and settings. Three experiments looked into treatment with percutaneous nephrolithotomy. Additionally, one study each investigated imaging perioperatively for endourological interventions, stone bacterial burden, and obstructive uropathy.
    UNASSIGNED: AS have been used in a plethora of laboratory experimental studies. Independent of their similarity to real urinary tract stones, they present a tremendous potential for testing and training for endourological interventions.
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  • 文章类型: Journal Article
    沙特尿石症指南是一套诊断建议,评估,和治疗沙特人口的尿石症。这些指南基于最新证据和专家共识,以改善患者预后并优化护理服务。它们涵盖了尿石症的各个方面,包括风险因素,诊断,医学和外科治疗,和预防策略。通过遵循这些准则,医疗保健专业人员可以提高沙特阿拉伯尿石症患者的护理质量。
    沙特尿石症指南小组由具有尿石症专业知识的泌尿外科专家组成,并与指导方法学专家进行咨询。参与本文件的所有小组成员都提交了声明,披露了任何潜在的利益冲突。
    沙特关于尿石症的指南是通过主要依靠既定的国际指南来采用或调整最适合沙特情况的指南而制定的。必要时,小组修改了来自不同来源的建议的措辞,以确保文件的一致性。为了解决现有准则中较少涉及的领域,小组进行了定向文献检索,寻找以英文发表的高质量证据,包括荟萃分析,随机对照试验,和前瞻性非随机比较研究。小组还搜索了包含沙特阿拉伯人口特有信息的当地相关研究。这些建议是根据GRADE术语和解释制定的,同时依赖于现有准则的现有证据摘要。
    UNASSIGNED: The Saudi Urolithiasis Guidelines are a set of recommendations for diagnosing, evaluating, and treating urolithiasis in the Saudi population. These guidelines are based on the latest evidence and expert consensus to improve patient outcomes and optimize care delivery. They cover the various aspects of urolithiasis, including risk factors, diagnosis, medical and surgical treatments, and prevention strategies. By following these guidelines, health-care professionals can improve care quality for individuals with urolithiasis in Saudi Arabia.
    UNASSIGNED: The Saudi Urolithiasis Guidelines Panel consists of urologists specialized in endourology with expertise in urolithiasis and consultation with a guideline methodologist. All panelists involved in this document have submitted statements disclosing any potential conflicts of interest.
    UNASSIGNED: The Saudi Guidelines on Urolithiasis were developed by relying primarily on established international guidelines to adopt or adapt the most appropriate guidance for the Saudi context. When necessary, the panel modified the phrasing of recommendations from different sources to ensure consistency within the document. To address areas less well covered in existing guidelines, the panel conducted a directed literature search for high quality evidence published in English, including meta analyses, randomized controlled trials, and prospective nonrandomized comparative studies. The panel also searched for locally relevant studies containing information unique to the Saudi Arabian population. The recommendations are formulated with a direction and strength of recommendation based on GRADE terminology and interpretation while relying on existing summaries of evidence from the existing guidelines.
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  • 文章类型: Journal Article
    UNASSIGNED: The objective of the study y was to evaluate factors which can improve shock wave lithotripsy (SWL) results to keep up with COVID-19 pandemic.
    UNASSIGNED: Between June 2020 and June 2021, patients with radio-opaque or faint radio-opaque upper urinary tract stones, stone attenuation value ≤1200 HU, and stones size <2.5 cm were treated by electrohydraulic SWL. Patients with respiratory tract symptoms elevated temperature, contact with COVID-19 patients, or positive COVID-19 swab 2 weeks preoperatively, skin-to-stone distance >11 cm, and body mass index >30 kg/m2 were excluded from the study. Patients were prospectively enrolled in SWL done at a rate of 40-50 SWs/min under combined ultrasound and fluoroscopy-guided, ramped into high power in the 1st 300 shocks. Success rate and complications were recorded.
    UNASSIGNED: Five hundred and ninety patients completed the study. The success rate after 1st session was 408/590 patients (69.15%) which was augmented by 2nd session to reach 527/590 patients 89.3%. The success rate was 96.2% at 3 months postoperatively. Most complications were mild (Grade 1 or 2).
    UNASSIGNED: SWL results improved using slow rate high power from the start of the session under combined fluoroscopy and ultrasound guidance. SWL may be a preferred option during a pandemic.
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  • 文章类型: Case Reports
    自发性Steinstrasse(“石街”)是输尿管内的石头集合,是罕见且研究不足的事件。感染等因素,肾功能改变,和梗阻程度用于定义最适当的治疗选择。治疗可以是保守的或手术的。其决定取决于临床表现。本文报道了在泌尿科诊所检查的一例59岁自发性Steinstrasse患者的罕见病例。由于肾功能改变,需要手术干预。患者目前正在接受代谢研究的随访。
    Spontaneous steinstrasse (\"stone street\") is a collection of stones within the ureter and is a rare and understudied event. Factors such as infection, altered kidney function, and degree of obstruction are used to define the most adequate therapeutic option. Treatment can be either conservative or surgical. The decision of which depends on the clinical presentation. This paper reports a rare case of a 59-year-old patient with spontaneous steinstrasse examined at a urology clinic. Surgical intervention was required because of altered kidney function. The patient is currently undergoing follow-up for the metabolic investigation.
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  • 文章类型: Journal Article
    在治疗尿石症之前预测成功很重要。我们旨在通过比较彩色多普勒超声(CDUS)显示的闪烁伪影(TA)与非对比计算机断层扫描(NCCT)中的结石密度来预测冲击波碎石(SWL)的成功。
    在2021年1月至2022年1月期间接受SWL的80例患者被纳入研究。包括NCCT时肾盂和输尿管近端结石5-20mm的患者。患者人口统计学,NCCT中的Hounsfield单位(HU),并记录CDUS中的TA等级。SWL后的无石率,额外的治疗,整体成功率,并评估TA与成功率之间的关联。
    平均年龄为47.41±15.08岁。平均BMI为24.49±3.67kg/m2。23例(28.8%)患者为TA0级,33例(41.2%)患者为1级,24例(30%)为2级。TA等级0、1和2级结石的平均HU分别为628±107、864±123和1166±292。HU随结石TA等级的增加而增加(p<0.01)。TA等级为0的患者的SWL平均次数为2.26±0.75,TA等级为2的患者为2.92±0.40。SWL会话的平均次数随着TA等级的增加而增加(p<0.01)。无石率随着TA等级的增加而降低。结石直径和TA是SWL成功的唯一预测因子。
    我们认为TA可能对预测SWL成功有用。
    UNASSIGNED: It is important to predict success before the treatment of urolithiasis. We aimed to predict the success of shock wave lithotripsy (SWL) by comparing twinkling artifact (TA) revealed through colour Doppler ultrasonography (CDUS) with stone density in non-contrast computed tomography (NCCT).
    UNASSIGNED: Eighty patients who underwent SWL between January 2021 and January 2022 were included in the study. Patients with stones of 5-20 mm in the renal pelvis and proximal ureter at NCCT were included. Patients\' demographics, Hounsfield units (HU) in NCCT, and TA grades in CDUS were recorded. The stone-free rate after SWL, additional treatments, overall success rates, and the association between TA and success rates were evaluated.
    UNASSIGNED: The mean age was 47.41 ±15.08 years. The mean BMI was 24.49 ±3.67 kg/m2. Twenty-three (28.8%) patients were TA grade 0, 33 (41.2%) patients were grade 1, and 24 (30%) were grade 2. The mean HU of TA grades 0, 1, and 2 of stones were 628 ±107, 864 ±123, and 1166 ±292, respectively. The HU increased along with the increase in the TA grade of the stone (p <0.01). The mean number of SWL sessions was 2.26 ±0.75 in patients with TA grade 0, and 2.92 ±0.40 in patients with TA grade 2. The mean number of SWL sessions increased along with the increase in TA grade (p <0.01). The stone-free rate decreased as the TA grade increased. Stone diameter and TA were the only predictors of SWL success.
    UNASSIGNED: We think that TA may be useful in predicting SWL success.
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  • 文章类型: Case Reports
    我们介绍了一个罕见的病例,其中一名63岁的男性有高血压病史,糖尿病,高脂血症,和以前的冠状动脉旁路移植术(CABG)表现为双侧髂外动脉接近闭塞。我们描述了碎石球囊血管成形术的使用,而不是传统的双管支架置入方法或改良的血管内修复(EVAR)来治疗闭塞。术前计算机断层扫描(CT)血管造影显示90%的主动脉远端和右髂外动脉闭塞,99%的左髂外动脉闭塞.患者在干预后三年保持无症状,右和左踝肱指数正常,分别为1.34和1.32。我们回顾了有关主动脉闭塞性疾病(AIOD)的现有文献,并讨论了新型和传统治疗方式的优缺点。了解所有治疗方案对于出现类似病例的医生至关重要。
    We present a rare case in which a 63-year-old male with a history of hypertension, diabetes mellitus, hyperlipidemia, and previous coronary artery bypass graft (CABG) presented with bilateral external iliac artery near occlusion. We describe the utilization of lithotripsy balloon angioplasty as opposed to the traditional double-barrel stenting method or modified endovascular repair (EVAR) to treat the occlusion. Pre-operative computed tomography (CT) angiography demonstrated a 90 percent occlusion of both the distal aorta and right external iliac artery, and 99 percent occlusion of the left external iliac. The patient remains symptom-free three years post-intervention with normal right and left ankle-brachial indices, 1.34 and 1.32 respectively. We review the available literature regarding aortoiliac occlusive disease (AIOD) and discuss the advantages and disadvantages of novel and traditional treatment modalities. Understanding all treatment options is crucial for physicians who are presented with similar cases.
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  • 文章类型: Journal Article
    冲击波碎石术(SWL)是治疗输尿管结石的重要工具,特别是当输尿管切除术(URS)不容易获得时。
    该研究的目的是确定与冲击波碎石术(SWL)治疗输尿管下段结石成功相关的因素。
    对2021年1月至2022年2月期间使用SWL治疗的105例输尿管下段结石患者进行回顾性分析。临床和结石参数,包括年龄,性别,和体重指数(BMI),石长,和石材密度进行了分析。使用导电碎石机Sonolithi-sys(EDAPTMS,Vaulx-en-Velin,法国)。我们评估了可能与成功的SWL治疗相关的可用临床和放射学特征。
    67/105例患者(63.8%)治疗成功。多因素logistic回归分析显示,成功的结果与平均结石密度(MSD)(95%CI:1.004-1.009)和患者年龄(95%CI:1.022-1.13)显着相关。性别,BMI,石长不是独立的预测因素。
    结石密度和患者年龄是下输尿管两次SWL后成功预后的独立预测因素。然而,性别,BMI,结石长度不能独立预测治疗成功。
    UNASSIGNED: Shockwave lithotripsy (SWL) is an important tool for treating ureteral stones, especially when ureteroscoy (URS) is not readily available.
    UNASSIGNED: The aim of the study was to identify factors associated with the success of shockwave lithotripsy (SWL) in the treatment of lower ureteral stones.
    UNASSIGNED: Total of 105 consecutive patients with single lower ureteral stones treated with SWL between January 2021 and February 2022 were reviewed retrospectively. Clinical and stone parameters including age, gender, and body mass index (BMI), stone length, and stone density were analyzed. SWL procedures were done using electro-conductive lithotripter Sonolith i-sys (EDAP TMS, Vaulx-en-Velin, France). We evaluated available clinical and radiologic features that might have been related to successful SWL treatment.
    UNASSIGNED: Treatment was successful in 67/105 patients (63.8%). Multivariate logistic regression revealed that a successful outcome was significantly related to mean stone density (MSD) (95% CI: 1.004- 1.009) and the patients age (95% CI: 1.022- 1.13). Gender, BMI, and stone length were not an independent predicting factors.
    UNASSIGNED: Stone density and patient age were independent predictors of successful outcome after two SWLs in the lower ureter. However, gender, BMI, and stone length did not independently predict treatment success.
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  • 文章类型: Journal Article
    小儿尿路结石在过去20年中更为常见,泌尿科医师在手术治疗方面面临着独特的挑战,因为这种特殊的人群被认为是结石复发的高危类别之一.鉴于这一现实,护理的重点是维持肾功能,实现完全无石状态,最重要的是避免结石复发。在这篇文章中,我们旨在对目前小儿肾结石的微创治疗进行全面综述。
    在截至2023年2月的全面PubMed搜索后,我们评估了74项研究的结果。本文是利用当前的泌尿外科指南撰写的。
    考虑到除了解剖异常(约30%的病例)外,在多达50%的病例中报告的代谢问题发生,小儿尿石症的治疗需要单独进行全面的代谢和泌尿外科检查。及时管理代谢失衡和阻塞性疾病是必要的。除了鼓励适当的液体消耗,建议改善尿量,并考虑使用药物治疗来提高尿柠檬酸盐水平。位置,内容,和石头的大小,收集系统的形态,尿路感染的存在,以及任何障碍物的存在,在决定最佳外科手术时,应考虑所有因素。
    由于仪器技术的明显进步和从成年患者中获得的专业知识的扩展,现在所有现代泌尿外科方法都被用于小儿尿石症的安全有效护理。其他微创手术,如输尿管肾镜和经皮肾镜取石术,需要更多的专业知识,并且可以通过精心管理成功应用,以获得出色的无结石率和最低的发病率。在这些程序中,在大多数上尿路结石病例中,冲击波碎石仍是首选。对于患有复杂和大结石以及解剖异常的儿科患者,开放手术仍将是首选治疗方法。
    UNASSIGNED: Pediatric urolithiasis has been more common over the past 20 years, and urologists have unique challenges in managing it surgically because this particular demographic is recognized as one of the high-risk categories for stone recurrence. Given this reality, care focuses on maintaining renal function, achieving total stone-free status, and most importantly avoiding stone recurrences. In this presented article, we aimed to make a comprehensive review of the current minimally invasive treatment of pediatric kidney stone disease.
    UNASSIGNED: We evaluated the results of 74 studies following a comprehensive PubMed search till February 2023. This article was written by making use of current urology guidelines.
    UNASSIGNED: Considering the reported occurrence of metabolic issues in up to 50% of cases in addition to the anatomic anomalies (about 30% of cases), the treatment of pediatric urolithiasis necessitates a full metabolic and urological examination on an individual basis. Timely management of metabolic imbalances and obstructive diseases is necessary. In addition to encouraging proper fluid consumption, it is advisable to improve urine volume and consider using medical therapeutics to raise urinary citrate levels. The location, content, and size of the stone(s), the morphology of the collecting system, the presence of urinary tract infection, as well as the presence of any obstruction, should all be taken into consideration while deciding on the best surgical procedure.
    UNASSIGNED: All modern endourological methods are now used in the safe and efficient care of pediatric urolithiasis as a consequence of the obvious advancements in instrument technology and expanding expertise derived from adult patients. Other minimally invasive procedures, such as ureterorenoscopy and percutaneous nephrolithotomy, require more expertise and can be successfully applied with careful management for an excellent stone-free rate with minimal morbidity. Of these procedures, shock wave lithotripsy is still the first choice in the majority of cases with upper tract calculi. Open surgery will still be the therapy of choice for pediatric patients with complicated and big stones as well as anatomical anomalies.
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