背景:视网膜血管闭塞,包括视网膜静脉阻塞和视网膜动脉阻塞,是视力障碍的常见原因。为了评估国家医疗负担,帮助完善眼科保健政策规划,我们调查了2011-2020年韩国视网膜血管闭塞性疾病的发病率.
方法:本研究是一项全国性的基于人群的回顾性研究,使用健康保险审查和评估(HIRA)服务的韩国国家健康索赔数据库的数据。我们根据国际疾病分类的视网膜血管阻塞代码(H34)及其子代码,确定了从2009年1月1日至2020年12月31日注册的视网膜血管阻塞疾病,第十次修订诊断代码。我们使用基于2015年韩国人口普查的整个韩国人口的数据来计算标准化发病率。
结果:我们确定了348,775名个体(男性,161,673[46.4%];女性,187,102[53.6%])伴有视网膜血管阻塞(H34),10451个人(男性,6,329[60.6%];女性,4,122[39.4%])合并视网膜中央动脉阻塞(H34.1),和252,810个人(男性,114,717[45.4%];女性,138,093[54.6%])在10年的研究期间发生视网膜静脉阻塞(H34.8)。视网膜血管阻塞的加权平均发生率为70.41(95%CI,70.18-70.65)例/100,000人年。视网膜中央动脉阻塞的加权平均发生率为2.10(95%CI,2.06-2.14)例/100,000人年。视网膜静脉阻塞的加权平均发生率为50.99(95%CI,50.79-51.19)例/100,000人年。
结论:到2020年,视网膜血管阻塞和视网膜静脉阻塞呈下降趋势。然而,视网膜中央动脉阻塞在2014年之前有所下降,并且在2020年之前保持稳定,没有明显的进一步下降.女性视网膜血管完全阻塞和视网膜静脉阻塞的发生率高于男性,而男性视网膜中央动脉阻塞的发生率较高。所有视网膜血管闭塞性疾病的发病率均随着年龄的增长而增加;视网膜血管完全阻塞和视网膜静脉阻塞的高峰年龄为75-79岁。视网膜中央动脉阻塞80-85岁.
BACKGROUND: Retinal vascular occlusions, including retinal vein occlusion and retinal artery occlusion, are common causes of visual impairment. In order to evaluate the national medical burden and help improve ophthalmic health care policy planning, we investigated the incidence of retinal vascular occlusive diseases from 2011 to 2020 in Korea.
METHODS: This study is a nationwide population-based retrospective study using data from the Korea national health claim database of the Health Insurance Review and Assessment (HIRA) service. We identified retinal vascular occlusive diseases registered from January 1, 2009, to December 31, 2020, according to the retinal vascular occlusion code (H34) and its sub-codes from international classification of disease, tenth revision diagnosis code. We used data from the entire Korean population based on the 2015 census of the population in Korea to calculate standardized incidence rates.
RESULTS: We identified 348,775 individuals (male, 161,673 [46.4%]; female, 187,102 [53.6%]) with incident retinal vascular occlusion (H34), 10,451 individuals (males, 6,329 [60.6%]; females, 4,122 [39.4%]) with incident central retinal artery occlusion (H34.1), and 252,810 individuals (males, 114,717 [45.4%]; females, 138,093 [54.6%]) with incident retinal vein occlusion (H34.8) during the 10-year study period. The weighted mean incidence rate of retinal vascular occlusion was 70.41 (95% CI, 70.18-70.65) cases/100,000 person-years. The weighted mean incidence rate of central retinal artery occlusion was 2.10 (95% CI, 2.06-2.14) cases/100,000 person-years. The weighted mean incidence rate of retinal vein occlusion was 50.99 (95% CI, 50.79-51.19) cases/100,000 person-years.
CONCLUSIONS: The total retinal vascular occlusion and retinal vein occlusion showed a decreasing trend until 2020. However, the central retinal artery occlusion decreased until 2014 and remained stable without a significant further decline until 2020. The incidence of total retinal vascular occlusion and retinal vein occlusion was higher in females than in males, while the incidence of central retinal artery occlusion was higher in males. All retinal vascular occlusive diseases showed an increasing incidence with older age; the peak age incidence was 75-79 years for total retinal vascular occlusion and retinal vein occlusion, and 80-85 years for central retinal artery occlusion.