■本研究旨在评估小梁切除术后网板曲率指数(LCCI)的短期和长期变化,并探讨影响这些变化的因素。
■在这次回顾中,观察性研究,纳入40例接受小梁切除术并随访至少2年的青光眼患者的40只眼。术前使用谱域光学相干断层扫描(Pre_OP)扫描视神经头区域,术后6个月内(Post_OP1),在最后一次访问(Post_OP2)。从六个不同平面(0°,30°,60°,90°,120°,和150°),并比较了它们的平均值。使用单变量和多变量线性回归分析来确定与LCCI变化量相关的临床因素。
■平均随访时间为38.3±16.8个月。在OP1后,平均LCCI从9.28±2.58下降到7.91±2.57(P<0.001),平均眼压从22.0±7.6mmHg降至12.2±3.8mmHg(P=0.001)。在Post_OP2,平均LCCI维持在7.74±2.49(当与Post_OP1相比时,P=0.56,当与Pre_OP相比时,P<0.001)。平均眼压为12.6±5.4mmHg(与Post_OP1相比,P=0.67,与Pre_OP相比,P<0.001)。长期LCCI变化与基线年龄相关(P=0.04),球形当量(P=0.02),随访期间的平均IOP(P=0.02),术前LCCI(P=0.04)。
■接受小梁切除术的青光眼在平均随访超过3年后显示LCCI减少。长期LCCI降低与年龄较小有关,随访期间平均IOP较低,较大的球面等效屈光不正,术前LCCI。
UNASSIGNED: This study aimed to evaluate both short-term and long-term changes in the lamina cribrosa curvature index (LCCI) following trabeculectomy and investigate the factors influencing these changes.
UNASSIGNED: In this retrospective, observational study, 40 eyes of 40 patients with glaucoma who underwent trabeculectomy and had a follow-up of at least 2 years were included. Optic nerve head area was scanned by using spectral-domain optical coherence tomography before surgery (Pre_OP), within 6 months postoperatively (Post_OP1), and at the last visit (Post_OP2). LCCI values calculated from B-scan images at six different planes (0°, 30°, 60°, 90°, 120°, and 150°) and their mean values were compared. Univariate and multivariate linear regression analyses were used to identify the clinical factors associated with the amount of LCCI changes.
UNASSIGNED: The mean follow-up time was 38.3 ± 16.8 months. At Post_OP1, the mean LCCI decreased from 9.28 ± 2.58 to 7.91 ± 2.57 (P < 0.001), and the mean intraocular pressure decreased from 22.0 ± 7.6 mm Hg to 12.2 ± 3.8 mm Hg (P = 0.001). At Post_OP2, the mean LCCI was maintained at 7.74 ± 2.49 (P = 0.56 when compared to Post_OP1 and P < 0.001 when compared to Pre_OP). The mean intraocular pressure was 12.6 ± 5.4 mm Hg (P = 0.67 when compared to Post_OP1 and P < 0.001 when compared to Pre_OP). Long-term LCCI changes were associated with baseline age (P = 0.04), spherical equivalent (P = 0.02), mean IOP during follow-ups (P = 0.02), and preoperative LCCI (P = 0.04).
UNASSIGNED: Glaucomatous eyes undergoing trabeculectomy demonstrated reductions in the LCCI after a mean follow-up of over 3 years. Greater long-term LCCI reduction was associated with younger age, lower mean IOP during follow-up period, greater spherical equivalent refractive error, and preoperative LCCI.