Postoperative complication

术后并发症
  • 文章类型: Journal Article
    没有关于胸外科手术后应选择的胸管数量和尺寸的标准指南。本研究旨在评估采用双尾纤导管(BPCs)引流策略对通过单孔电视辅助胸外科(VATS)进行肺叶切除术的患者的影响。
    对2021年8月至2022年8月在大连理工大学肿瘤医院胸外科接受单孔肺叶切除术的患者进行了回顾性研究。根据所采取的引流策略将患者分为以下两组:(I)传统胸管(TCT)组;(II)BPC组。测量的结果包括术后并发症,通过Clavien-Dindo方法测量,术后患者疼痛视觉模拟评分(VAS)。
    总共,868例患者在研究期间接受了肺切除术,排除后,回顾了470例接受单行肺叶切除术的患者的资料(TCT组235例,和BPC组中的235)。两组基线资料比较差异无统计学意义(P>0.05)。术后并发症发生率(7.7%vs.19.1%)和术后7-24小时的VAS疼痛评分(3.3±1.0vs.3.7±1.5)和25-48小时(3.1±0.8vs.BPC组的3.6±1.5)明显低于TCT组(均P<0.001)。此外,术后住院时间(4.6±1.5vs.5.4±4.5天)和残余肺的塌陷率(19.2%±9.1%vs.BPC组20.9%±9.6%)优于TCT组(P<0.05)。单变量和多变量分析的结果表明,TCT引流策略是减少术后并发症的独立危险因素。手术后7-24和25-48小时,中度或重度疼痛评分降低。
    我们的BPCs引流策略降低了单管胸腔镜肺叶切除术患者术后并发症的发生率,减轻了术后疼痛,是安全可行的。
    UNASSIGNED: There are no standard guidelines regarding the number and size of chest tubes that should be selected after thoracic surgery. This study aimed to evaluate the effects of adopting a drainage strategy with bi-pigtail catheters (BPCs) on patients undergoing lobectomy by uniportal video-assisted thoracic surgery (VATS).
    UNASSIGNED: A retrospective study was performed of patients undergoing uniportal lobectomy at the Department of Thoracic Surgery of the Cancer Hospital of Dalian University of Technology between August 2021 and August 2022. The patients were divided into the following two groups according to the drainage strategy adopted: (I) a traditional chest tube (TCT) group; and (II) a BPC group. The outcomes measured included postoperative complications, as measured by the Clavien-Dindo method, and the visual analogue scale (VAS) pain scores of the patients after surgery.
    UNASSIGNED: In total, 868 patients underwent lung resection during the study period, after exclusion, the data of 470 patients who underwent uniport lobectomy were reviewed (235 in the TCT group, and 235 in the BPC group). There were no statistically significant differences between the two groups in terms of baseline data (P>0.05). The incidence of postoperative complications (7.7% vs. 19.1%) and postoperative VAS pain scores at 7-24 hours (3.3±1.0 vs. 3.7±1.5) and 25-48 hours (3.1±0.8 vs. 3.6±1.5) were significantly lower in the BPC group than the TCT group (all P<0.001). Additionally, the postoperative length of stay (4.6±1.5 vs. 5.4±4.5 days) and the collapse rate of the residual lung (19.2%±9.1% vs. 20.9%±9.6%) of the BPC group were better than those of the TCT group (P<0.05). The results of univariable and multivariable analyses showed that a drainage strategy with a TCT was an independent risk factor for decreased postoperative complications, and reduced moderate or severe pain scores at 7-24 and 25-48 hours after surgery.
    UNASSIGNED: Our drainage strategy with BPCs decreased the incidence of postoperative complications and alleviated the postoperative pain of patients undergoing lobectomy by uniportal VATS and is safe and feasible.
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  • 文章类型: Journal Article
    本研究旨在全面概述成人输尿管重建特有的并发症,强调他们的介绍,诊断,输尿管结构疾病的治疗和管理。
    这篇综述涉及对现有文献和案例研究有关输尿管重建的深入分析,重点检查手术后可能出现的并发症的范围。特别注意每个并发症的呈现,所涉及的诊断过程,以及后续的管理策略。
    输尿管重建术可以治疗输尿管狭窄疾病,发病率低;然而,并发症,虽然不常见,会有严重的后果。最显著的并发症包括尿外渗,狭窄复发,尿路感染,筋膜室综合征,有症状的膀胱输尿管反流,和Boari皮瓣坏死。每种并发症都提出了独特的诊断挑战,并需要特定的管理方法。
    输尿管重建术是治疗输尿管狭窄的有效方法。对输尿管重建后患者可能经历的潜在并发症有深刻的了解不仅对于充分咨询患者至关重要,而且还有助于在出现并发症时及时诊断和管理。
    UNASSIGNED: This study aimed to provide a comprehensive overview of the complications unique to ureteral reconstruction in adults, emphasizing their presentation, diagnosis, and management in the treatment of ureteral structure disease.
    UNASSIGNED: This review involves an in-depth analysis of existing literature and case studies pertaining to ureteral reconstruction, with a focus on examining the range of complications that can arise post-surgery. Special attention is given to the presentation of each complication, the diagnostic process involved, and the subsequent management strategies.
    UNASSIGNED: Ureteral reconstruction can treat ureteral stricture disease with low morbidity; however, complications, although uncommon, can have severe consequences. The most notable complications include urinary extravasation, stricture recurrence, urinary tract infections, compartment syndrome, symptomatic vesicoureteral reflux, and Boari flap necrosis. Each complication presents unique diagnostic challenges and requires specific management approaches.
    UNASSIGNED: Ureteral reconstruction is a highly effective treatment for ureteral stricture disease. Having a strong understanding of the potential complications that patients may experience following ureteral reconstruction is not only critical to adequately counsel patients but also facilitate prompt diagnosis and management of complications when they arise.
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  • 文章类型: Case Reports
    脾动脉瘤(SAA)是最常见的内脏动脉瘤,如果破裂会导致严重的后果。本报告介绍了一名71岁的女性,该女性在接受胰十二指肠切除术治疗胰头癌19年后突然发生严重的胃肠道出血。病人带着休克的迹象来到医院,影像学显示SAA破裂并伴有胃穿孔。急诊治疗涉及血管内技术,稳定了病人并控制了出血.该病例强调了快速诊断的重要性和血管内治疗在治疗SAA破裂中的有效性。特别是有复杂手术史的患者。
    Splenic artery aneurysm (SAA) is the most common visceral artery aneurysm and can lead to severe outcomes if ruptured. This report presents the case of a 71-year-old female who experienced a sudden and severe gastrointestinal hemorrhage 19 years after undergoing pancreaticoduodenectomy for pancreatic head cancer. The patient arrived at the hospital with signs of shock, and imaging revealed an SAA rupture with associated gastric perforation. Emergency treatment involved endovascular techniques, which stabilized the patient and controlled the bleeding. This case highlights the importance of rapid diagnosis and the effectiveness of endovascular therapy in managing SAA rupture, particularly in patients with complex surgical histories.
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  • 文章类型: Journal Article
    新辅助免疫疗法和化学疗法(NICT)的结合已成为局部晚期胃癌(LAGC)的常用治疗方案。然而,NICT后胃癌根治术(NICT-G)的安全性和有效性仍存在争议.本研究旨在分析影响NICT-G术后并发症(POCs)的危险因素。此外,旨在构建列线图,为预测POCs提供临床参考。
    这项研究包括2020年1月至2024年1月在中国人民解放军总医院第一医学中心接受NICT-G治疗的177名患者。单变量和多变量logistic回归模型用于评估影响POCs的危险因素,并建立了列线图模型。为了评估列线图模型的区分度和准确性,测量受试者工作特征曲线下面积(AUC)和校准曲线.
    在177名接受NICT-G的患者中,病理完全缓解率和主要病理缓解率分别为15.8%和45.2%,分别,而总体和严重治疗相关不良事件的发生率分别为71.8%和15.8%,分别。此外,43例(24.3%)患者出现总体POC(Clavien-Dindo分类≥II)。单变量和多变量逻辑分析表明,年龄≥70岁,估计失血更多,血小板/淋巴细胞比值(PLR)≤196,中性粒细胞/淋巴细胞比值(NLR)>1.33,非R0切除,体重指数(BMI)<18.5kg/m2是总体POC的独立危险因素(p<0.05)。使用上述变量建立的列线图模型显示,预测POC风险的AUC(95%置信区间[CI])为0.808(95%CI):0.731-0.885。校准曲线表明,列线图的预测曲线与实际POC拟合良好(Hosmer-Lemeshow检验:χ2=5.76,P=0.451)。
    NICT-G中总体POC的独立危险因素是年龄≥70岁,估计失血更多,PLR≤196,NLR>1.33,非R0切除,BMI<18.5kg/m2。基于上述指标建立的列线图模型在预测POC风险方面显示出更好的准确性。
    UNASSIGNED: The combination of neoadjuvant immunotherapy and chemotherapy (NICT) has become a common treatment regimen for locally advanced gastric cancer (LAGC). However, the safety and efficacy of radical gastrectomy following NICT (NICT-G) remain controversial. This study aimed to analyze the risk factors influencing postoperative complications (POCs) after NICT-G. Additionally, it aimed to construct a nomogram to provide a clinical reference for predicting POCs.
    UNASSIGNED: This study included 177 patients who received NICT-G at the Chinese PLA General Hospital First Medical Center from January 2020 to January 2024. Univariable and multivariable logistic regression models were used to evaluate the risk factors influencing POCs, and a nomogram model was constructed. To evaluate the discrimination and accuracy of the nomogram model, the area under the receiver operating characteristic curve (AUC) and the calibration curve were measured.
    UNASSIGNED: In 177 patients who received NICT-G, the pathological complete response and major pathological response rates were 15.8% and 45.2%, respectively, whereas the rates of the overall and severe treatment-related adverse events were 71.8% and 15.8%, respectively. In addition, 43 (24.3%) patients developed overall POCs (Clavien-Dindo classification ≥ II). Univariable and multivariable logistic analyses showed that age ≥70 years, greater estimated blood loss, platelet/lymphocyte ratio (PLR) ≤196, neutrophil/lymphocyte ratio (NLR) >1.33, non-R0 resection, and body mass index (BMI) < 18.5 kg/m2 were independent risk factors for overall POCs (p < 0.05). The nomogram model developed using the abovementioned variables showed that the AUC (95% confidence interval [CI]) was 0.808 (95% CI): 0.731-0.885 in predicting the POC risk. The calibration curves showed that the prediction curve of the nomogram was a good fit for the actual POCs (Hosmer-Lemeshow test: χ2 = 5.76, P = 0.451).
    UNASSIGNED: The independent risk factors for overall POCs in the NICT-G were age ≥ 70 years, greater estimated blood loss, PLR ≤ 196, NLR > 1.33, non-R0 resection, and BMI < 18.5 kg/m2. The nomogram model developed based on the abovementioned indicators showed better accuracy in predicting the POC risk.
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  • 文章类型: Journal Article
    目的:本研究旨在阐明隆突下转移模式,胸段食管鳞状细胞癌的左、右喉返神经淋巴结清扫及探讨相应的淋巴结清扫策略。
    方法:对2020年12月至2024年4月行食管切除术的胸段食管鳞癌患者进行回顾性分析。隆突下的危险因素,采用卡方检验和多因素logistic回归分析确定左、右喉返神经淋巴结转移。我们根据不同的临床病理特征可视化了这些特定淋巴结的转移率。隆突下之间的相关性,同时分析左右喉返淋巴结转移及术后并发症。
    结果:共纳入503例胸段食管鳞癌患者行食管切除术。隆突下的转移率,左右喉返神经淋巴结占10.3%,10.3%,10.9%,分别。淋巴管浸润状态和肿瘤位置是隆下和右喉返神经淋巴结转移的重要预测因素,分别为(P<0.001和P=0.013)。对于左喉返神经淋巴结转移,年龄较小(P=0.020)和淋巴管浸润(P=0.009)是显著的危险因素.此外,肺部感染是隆突下夹层术后最常见的并发症,左右喉返淋巴结。吻合口漏发生率差异无统计学意义(P=0.872)。肺部感染(P=0.139),乳糜胸(P=0.702),隆突下淋巴结清扫队列和保留队列之间的声音嘶哑(P=0.179)。与保留队列相比,右侧(P=0.042)和左侧(P=0.010)喉返神经淋巴结清扫队列的声音嘶哑发生率显着增加,发病率分别为5.9%和6.7%,分别。
    结论:隆突下转移率,胸段食管鳞癌中左右喉返神经淋巴结均超过10%。隆突下淋巴结清扫术不会增加术后并发症风险,喉返神经淋巴结清扫术显著增加了声音嘶哑的发生率。因此,隆突下淋巴结的淋巴结清扫应常规进行,而喉返神经淋巴结清扫术可以在特定患者中选择性进行。
    OBJECTIVE: This research aimed to clarify the metastatic patterns of subcarinal, right and left recurrent laryngeal nerve lymph nodes in thoracic esophageal squamous cell carcinoma and to investigate appropriate strategies for lymph node dissection.
    METHODS: Patients with thoracic esophageal squamous cell carcinoma receiving esophagectomy from December 2020 to April 2024 were retrospectively analyzed. Risk factors for subcarinal, right and left recurrent laryngeal nerve lymph nodes metastasis were determined by chi-square test and multivariate logistic regression analysis. We visualized the metastasis rates of these specific lymph nodes based on the different clinicopathological characteristics. Correlation between subcarinal, right and left recurrent laryngeal lymph nodes metastasis and postoperative complications were also analyzed.
    RESULTS: A total of 503 thoracic esophageal squamous carcinoma patients who underwent esophagectomy were enrolled. The metastasis rates of subcarinal, right and left recurrent laryngeal nerve lymph nodes were 10.3%, 10.3%, and 10.9%, respectively. The lymphovascular invasion status and tumor location were the significant predictors for subcarinal and right recurrent laryngeal nerve lymph nodes metastasis, respectively (P < 0.001 and P = 0.013). For left recurrent laryngeal nerve lymph node metastasis, younger age (P = 0.020) and presence of lymphovascular invasion (P = 0.009) were significant risk factors. Additionally, pulmonary infection is the most frequent postoperative complication in patients with dissection of subcarinal, right and left recurrent laryngeal lymph nodes. There was no significant difference in the incidence of anastomotic leakage (P = 0.872), pulmonary infection (P = 0.139), chylothorax (P = 0.702), and hoarseness (P = 0.179) between the subcarinal lymph node dissection cohort and the reservation cohort. The incidence of hoarseness significantly increased in both right (P = 0.042) and left (P = 0.010) recurrent laryngeal nerve lymph nodes dissection cohorts compared by the reservation cohorts, with incidence rates of 5.9% and 6.7%, respectively.
    CONCLUSIONS: The metastasis rates of subcarinal, right and left recurrent laryngeal nerve lymph nodes in thoracic esophageal squamous cell carcinoma were all over 10%. The dissection of subcarinal lymph nodes does not increase postoperative complications risk, while recurrent laryngeal nerve lymph nodes dissection significantly increases the incidence of hoarseness. Thus, lymph node dissection of subcarinal lymph nodes should be conducted routinely, while recurrent laryngeal nerve lymph nodes dissection may be selectively performed in specific patients.
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  • 文章类型: Journal Article
    评估术中监测和干预局部脑氧饱和度水平是否可以降低心血管手术患者术后认知功能障碍的发生率并有助于患者预后。
    Cochrane图书馆,PubMed,从2000年1月1日至2022年5月1日,系统检索了WebofScience中涉及脑氧饱和度对心血管手术后患者认知功能影响的相关随机对照试验。主要结果是术后认知功能障碍的发生率。次要结果是住院时间,重症监护病房(ICU)住院时间,机械通气的长度,体外循环的长度,和其他主要的术后结果,如肾功能衰竭,感染,心律失常,医院死亡率,和中风。使用风险比或标准化平均差以95%置信区间(CI)汇集数据。原始研究方案在PROSPERO(CRD42020178068)中前瞻性注册。
    共13项随机对照试验,涉及1669例心血管手术患者。与对照组相比,干预组术后认知功能障碍的风险显著降低(RR=0.50;95%CI:0.30~0.85;p=0.01;I2=71%).干预组重症监护病房的住院时间也明显短于对照组(标准均差(SMD)=-0.14;95%CI:-0.26至-0.01;p=0.03;I2=26%)。单变量荟萃回归分析显示年龄是异质性的主要来源。
    我们目前的研究表明,术中脑氧饱和度监测和干预可以显着降低术后认知功能障碍的发生率,干预后重症监护病房的住院时间大大减少。鉴于本次审查中的一些限制,更高质量,我们仍需要长期试验来证明我们的发现.
    UNASSIGNED: To assess whether intraoperative monitoring and intervention of regional cerebral oxygen saturation levels can reduce the incidence of postoperative cognitive dysfunction in patients undergoing cardiovascular surgery and contribute to patient prognosis.
    UNASSIGNED: The Cochrane Library, PubMed, and the Web of Science were systematically searched for relevant randomized controlled trials involving the effects of cerebral oxygen saturation on the cognitive function of patients after cardiovascular surgery from January 1, 2000 to May 1, 2022. The primary outcome was the incidence of postoperative cognitive dysfunction. The secondary outcomes were length of hospital stay, length of intensive care unit (ICU) stay, length of mechanical ventilation, length of cardiopulmonary bypass, and other major postoperative outcomes such as renal failure, infection, arrhythmia, hospital mortality, and stroke. Data were pooled using the risk ratio or standardized mean difference with 95% confidence interval (CI). The original study protocol was registered prospectively with PROSPERO (CRD42020178068).
    UNASSIGNED: A total of 13 randomized controlled trials involving 1669 cardiovascular surgery patients were included. Compared with the control group, the risk of postoperative cognitive dysfunction was significantly lower in the intervention group (RR = 0.50; 95% CI: 0.30 to 0.85; p = 0.01; I 2 = 71%). The Duration of stay in intensive care units in the intervention group was also significantly shorter than that in the control group (standard mean difference (SMD) = -0.14; 95% CI: -0.26 to -0.01; p = 0.03; I 2 = 26%). Univariate meta-regression analyses showed that age is a major source of heterogeneity.
    UNASSIGNED: Our current study suggests that intraoperative cerebral oxygen saturation monitoring and intervention can significantly reduce the incidence of postoperative cognitive dysfunction, and the length of intensive care unit stay after intervention is considerably reduced. Given that some limits in this review, more high-quality, and long-term trials are still needed to certify our findings.
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  • 文章类型: Case Reports
    上颌骨节段截骨术,一种用于正颌手术的手术技术,涉及腭粘膜撕裂的风险,会导致严重的并发症.在这里,我们报道了1例AngleII类错牙合的女性,她接受了多节段选择性上颌骨截骨术和隆突术,以矫正错牙合并增强面部轮廓.手术后一周,病人出现了腭部溃疡。我们采用了包括14天高压氧治疗和常规方式的综合治疗方法;这种方法产生了良好的结果。我们的案例强调了立即干预的重要性以及综合方法预防口鼻瘘形成的协同潜力。我们的发现表明高压氧治疗促进伤口愈合,尤其是颌面手术引起并发症的患者。
    Segmental maxillary osteotomy, a surgical technique used in orthognathic surgery, involves the risk of palatal mucosa tearing, which can lead to severe complications. Herein, we report the case of a woman with Angle class II malocclusion who underwent multiple elective segmental maxillary osteotomy and augmentation genioplasty procedures for the correction of her malocclusion and the enhancement of her facial profile. A week after surgery, the patient developed a palatal ulcer. We adopted a comprehensive treatment approach involving 14-day hyperbaric oxygen therapy and conventional modalities; this approach resulted in favorable outcomes. Our case underscores the importance of immediate intervention and the synergistic potential of the comprehensive approach against oronasal fistula formation. Our findings indicate that hyperbaric oxygen therapy promotes wound healing, particularly in patients with complications arising from maxillofacial surgery.
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  • 文章类型: Journal Article
    背景:最近的研究表明,这种情况与结肠癌患者的预后有关。然而,侧方在手术结局中的作用尚不清楚.在这项研究中,对于接受手术干预的结肠癌患者,我们试图证明片面性在术后结果中的真正作用。方法:这是一项使用2009年至2013年美国外科医生学会-国家外科质量改进计划(ACS-NSQIP)数据库的倾向评分匹配研究。根据相关的诊断和程序代码创建包括右侧和左侧结肠癌的侧视组。术后30天死亡率,发病率,整体并发症,进行倾向评分匹配后,对住院总时间进行分析。结果:在接受相关手术的24,436例结肠癌患者中,15,945例患者患有右侧癌症,8941例患者患有左侧癌症。右半结肠癌患者术前合并症较多,包括高龄,女性性别,高血压,呼吸困难,贫血,低蛋白血症,和高美国麻醉医师协会等级(SMD>0.1)。术后死亡率,包括重新插管在内的疾病,出血,尿路感染和深静脉血栓形成,术后总体并发症,和住院总时间与右侧癌显著相关(p<0.05)。1:1倾向评分匹配后,右侧癌(2.3%)和左侧癌(2.4%)患者的术后死亡率无显著差异.左侧结肠癌患者术后并发症明显增多,更多的整体并发症,和更长的总住院时间。结论:右侧癌症患者的临床特征和术后结局较差。在倾向得分匹配后,左侧癌症患者的术后结局比右侧癌症患者差.
    Background: Recent investigations have suggested that-sidedness is associated with the prognosis of colon cancer patients. However, the role of sidedness in surgical outcome is unclear. In this study, we tried to demonstrate the real role of sidedness in postoperative results for colon cancer patients receiving surgical intervention. Methods: This is a propensity score matching study using the database of the American College of Surgeons-National Surgical Quality Improvement Program (ACS-NSQIP) from 2009 to 2013. Sidedness groups including right-sided and left-sided colon cancer were created according to the associated diagnosis and procedure codes. Postoperative 30-day mortality, morbidity, overall complications, and total length of hospital stay were analyzed after performing propensity score matching. Results: Out of a total of 24,436 colon cancer patients who received associated operations, 15,945 patients had right-sided cancer and 8941 patients had left-sided cancer. Right-sided colon cancer patients were accompanied by more preoperative comorbidities including old age, female sex, hypertension, dyspnea, anemia, hypoalbuminemia, and a high American Society of Anesthesiologists grade (SMD > 0.1). Postoperative mortality, morbidities including re-intubation, bleeding, urinary tract infection and deep vein thrombosis, postoperative overall complications, and total length of hospital stay were significantly associated with right-sided cancer (p < 0.05). After 1:1 propensity score matching, postoperative mortality was not significantly different between right-sided cancer (2.3%) and left-sided cancer (2.4%) patients. The patients with left-sided colon cancer had significantly more postoperative morbidities, more overall complications, and longer total length of hospital stay. Conclusions: Poor clinical characteristics and postoperative outcomes were noted in right-sided cancer patients. After propensity score matching, left-sided cancer patients had worse postoperative outcomes than those with right-sided cancer.
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  • 文章类型: Journal Article
    应用半肝流入闭塞(HIO)和全肝流入闭塞(TIO)是两种常见的肝切除术方法。然而,其疗效和安全性仍存在争议.
    在2023年1月15日之前发表的随机对照试验(RCT)通过系统的文献检索纳入,比较了HIO和TIO的临床结果。主要结果是估计的失血量(EBL)。三位独立作者筛选并提取了数据,并通过共识解决了分歧。ROB2.0工具用于评估偏倚风险。
    在荟萃分析中对9项研究中的1026名患者(511TIO和515HIO)进行了分析。TIO和HIO组的EBL相似,而HIO与需要输血的患者比例较低相关(P=0.002),较少单位的血液转移(P<0.001)和较低的总并发症发生率(P=0.008)。TIO和HIO的死亡率无显著差异(P=0.37),住院时间(P=0.97),胆漏率(P=0.58),肝衰竭发生率(P=0.96),再手术率(P=0.48),术后出血发生率(P=0.93)和术后腹水发生率(P=0.96)。HIO的手术时间通常不超过TIO的15分钟(P<0.001)。
    与TIO相比,HIO增加了手术时间,但未能进一步降低肝脏手术患者的EBL。然而,尽管操作复杂,由于对血液制品的消耗和术后并发症的类似影响,建议使用HIO。
    UNASSIGNED: Application of hemihepatic inflow occlusion (HIO) and total hepatic inflow occlusion (TIO) are two common approaches for hepatectomy. However, their efficacy and safety remain controversial.
    UNASSIGNED: Randomized control trials (RCTs) published before 15t January 2023 were included by a systematic literature search, which compared the clinical outcomes between HIO and TIO. The primary outcome was the estimated blood loss (EBL). Three independent authors screened and extracted the data and resolved disagreements by consensus. The ROB2.0 tool was used for evaluating the risk of bias.
    UNASSIGNED: A total of 1026 patients (511 TIO and 515 HIO) from 9 studies were analyzed in the meta-analyses. The EBL between TIO and HIO group was similar, while HIO was associated with a lower proportion of patients required transfusion (P=0.002), less units of blood transferred (P<0.001) and a lower overall complication rate (P=0.008). There were no significant differences between TIO and HIO in mortality (P=0.37), length of stay (P=0.97), bile leak rate (P=0.58), liver failure rate (P=0.96), reoperation rate (P=0.48), postoperative haemorrhage rate (P=0.93) and incidence of postoperative ascites (P=0.96). The operative time of HIO was usually no more than 15 min longer than that of TIO (P<0.001).
    UNASSIGNED: Comparing with the TIO, HIO increased the operative time and failed to further reduce the EBL in patients with liver surgery. However, despite the complexity of the operation, HIO was recommended due to the similar effect on the consumption of blood products and the postoperative complications.
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  • 文章类型: Journal Article
    背景:肺切除术后常见术后并发症的危险因素之间的关系,如空气泄漏,肺不张,和心律不齐,和患者特征,包括营养状况或围手术期因素,还没有被充分阐明。
    方法:回顾性分析接受肺切除术治疗的99例非小细胞肺癌患者术后常见并发症的危险因素。
    结果:在多变量分析中,男性(P=0.01),年龄≥65岁(P<0.01),慢性阻塞性肺疾病(COPD)的共存(P<0.01),上叶(P<0.01),手术时间≥155min(P<0.01),淋巴浸润(P=0.01)是术后并发症的重要因素。男性(P<0.01),年龄≥65岁(P=0.02),体重指数(BMI)<21.68(P<0.01),COPD共存(P=0.02),手术时间≥155min(P=0.01)是术后严重并发症的重要因素。男性(P=0.01),BMI<21.68(P<0.01),胸腔镜手术(P<0.01),手术时间≥155min(P<0.01)是术后漏气的危险因素。COPD共存(P=0.01)和哮喘共存(P<0.01)是术后肺不张的危险因素。预后营养指数(PNI)<45.52(P<0.01),肺叶切除术或扩大切除术多于肺叶切除术(P=0.01),手术时间≥155min(P<0.01)是术后心律失常的危险因素。
    结论:低BMI,胸腔镜手术,手术时间较长是术后漏气的重要危险因素。COPD共存和哮喘共存是术后肺不张的重要危险因素。PNI,手术时间,和手术方式是术后心律失常的危险因素。有这些因素的患者应监测术后并发症。
    背景:金泽医科大学机构审查委员会批准了这项回顾性研究的方案(批准号:I392),并获得所有患者的书面知情同意书.
    BACKGROUND: The relationship between risk factors of common postoperative complications after pulmonary resection, such as air leakage, atelectasis, and arrhythmia, and patient characteristics, including nutritional status or perioperative factors, has not been sufficiently elucidated.
    METHODS: One thousand one hundred thirty-nine non-small cell lung cancer patients who underwent pulmonary resection were retrospectively analyzed for risk factors of common postoperative complications.
    RESULTS: In a multivariate analysis, male sex (P = 0.01), age ≥ 65 years (P < 0.01), coexistence of chronic obstructive pulmonary disease (COPD) (P < 0.01), upper lobe (P < 0.01), surgery time ≥ 155 min (P < 0.01), and presence of lymphatic invasion (P = 0.01) were significant factors for postoperative complication. Male sex (P < 0.01), age ≥ 65 years (P = 0.02), body mass index (BMI) < 21.68 (P < 0.01), coexistence of COPD (P = 0.02), and surgery time ≥ 155 min (P = 0.01) were significant factors for severe postoperative complication. Male sex (P = 0.01), BMI < 21.68 (P < 0.01), thoracoscopic surgery (P < 0.01), and surgery time ≥ 155 min (P < 0.01) were significant risk factors for postoperative air leakage. Coexistence of COPD (P = 0.01) and coexistence of asthma (P < 0.01) were significant risk factors for postoperative atelectasis. Prognostic nutrition index (PNI) < 45.52 (P < 0.01), lobectomy or extended resection more than lobectomy (P = 0.01), and surgery time ≥ 155 min (P < 0.01) were significant risk factors for postoperative arrhythmia.
    CONCLUSIONS: Low BMI, thoracoscopic surgery, and longer surgery time were significant risk factors for postoperative air leakage. Coexistence of COPD and coexistence of asthma were significant risk factors for postoperative atelectasis. PNI, surgery time, and surgical procedure were revealed as risk factors of postoperative arrhythmia. Patients with these factors should be monitored for postoperative complication.
    BACKGROUND: The Institutional Review Board of Kanazawa Medical University approved the protocol of this retrospective study (approval number: I392), and written informed consent was obtained from all patients.
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