背景:乙酰六肽-8,也称为Argireline,是一个话题,短效,合成肽最近因其抗皱作用而受到欢迎。该试剂已成为肉毒杆菌神经毒素的更容易获得的替代品。
目的:这项研究评估了2013年至2023年美国对乙酰六肽-8的公共利益,如Google上的搜索量所述,最常用的搜索引擎
方法:我们分析了从2013年1月1日至2023年1月1日的纵向相对每月搜索量,以寻找与乙酰六肽相关的术语。在此期间,我们将“肉毒杆菌毒素”的互联网搜索趋势与“Argireline”进行了比较。“
结果:术语“Argireline”和“瓶装肉毒杆菌”在2022年的搜索量均大幅增加。尽管它的搜索量急剧增加,“Argireline”比“肉毒杆菌”搜索次数少,“有一个稳定的,在过去十年中,搜索量呈上升趋势。
结论:对乙酰六肽-8的兴趣增加可能是由于其成本效益和用作肉毒杆菌神经毒素替代品。负担能力,非处方可用性,并且易于自我应用该药物表明其具有增强美容皮肤病护理可及性的潜力。
BACKGROUND: Acetyl hexapeptide-8, also known as Argireline, is a topical, short-acting, synthetic peptide that has recently gained popularity for its antiwrinkle effects. This agent has emerged as a more accessible alternative to botulinum
neurotoxin.
OBJECTIVE: This study evaluates the public interest in acetyl hexapeptide-8 in the United States from 2013 to 2023, as described by search volume on Google, the most-used search engine.
METHODS: We analyzed the longitudinal relative monthly search volume from January 1, 2013, to January 1, 2023, for acetyl hexapeptide-related terms. We compared the internet search trends for \"Botox\" during this period to \"Argireline.\"
RESULTS: The terms \"Argireline\" and \"Botox in a Bottle\" both had substantial increases in search volume in 2022. Although its search volume is drastically increasing, \"Argireline\" was less searched than \"Botox,\" which had a stable, up-trending search volume over the past decade.
CONCLUSIONS: The increasing interest in acetyl hexapeptide-8 may be due to its cost-effectiveness and use as a botulinum
neurotoxin alternative. Affordability, over-the-counter availability, and ease of self-application of the agent suggest its potential to enhance accessibility to cosmetic dermatologic care.