Mondor disease

Mondor 病
  • 文章类型: Case Reports
    Mondor病是主要位于胸腹壁的浅表性血栓性静脉炎,中上臂,和阴茎。这种疾病可以影响所有30岁以上的人,无论种族,种族,但对女性的影响大于男性。本研究案例的重要性在于成为阿尔巴尼亚首例报告的Mondor病病例。
    方法:在本研究中,据报道,一例浅表血栓性静脉炎影响右胸壁的胸腹静脉。注意到乳房下外象限有明显的脐带。病人,一名49岁的女性从2021年3月开始绝经,出现胸痛,应该进行两个月的夸大体力活动。
    进行了详细的主观和客观检查。所有实验室数据,包括COVID-19检测,显示除ESR外的正常范围值。布洛芬治疗2周,胸痛消退,但胸壁可触及的脊髓持续存在。
    结论:回顾文献并在彩色多普勒检查后得出此诊断结论。由于以前没有这种临床病例的经验,因此很难确定诊断。
    UNASSIGNED: Mondor Disease is superficial thrombophlebitis mostly located in the thoracic-abdominal wall, mid-upper arm, and penis. The disease can affect all people over 30 years old regardless of race, ethnicity but affects women more than men. The importance of this study case consists on being the first reported case of Mondor Disease in Albania.
    METHODS: In this study, a case of superficial thrombophlebitis affecting the thoraco-epigastric veins in the right chest wall is reported. Evidence of a palpable cord in the inferior outer quadrant of the breast was noted. The patient, a 49-year-old female who has been in menopause from March of 2021, presented with chest pain ought to two months of exaggerated physical activity.
    UNASSIGNED: A detailed subjective and objective examination was performed. All laboratory data, including tests for COVID-19, showed normal range value except ESR. For 2 weeks under treatment with Ibuprofen, the chest pain was subsided but the palpable cord in the chest wall was persistent.
    CONCLUSIONS: Reviewing the literature and after the Color Doppler examination it has been concluded in this diagnose. It was difficult to determine the diagnosis because of no previous experience with such clinical case.
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  • 文章类型: Case Reports
    阴茎Mondor病是一种罕见的疾病,其特征是阴茎背侧浅静脉血栓形成,其发病机制尚不清楚。长期或积极的性交已被确定为潜在的危险因素。我们介绍了一例54岁的男子,他在侵略性活动后出现了阴茎肿块。对背浅静脉血栓的诊断采用超声诊断,MRI证实。患者接受保守治疗并放弃性活动。四周后,观察到血栓完全消退.这个案例强调了医疗保健专业人员的重要性,尤其是泌尿科医生,在识别和管理阴茎蒙多的疾病。
    Penile Mondor\'s disease is a rare condition characterized by superficial dorsal vein thrombosis of the penis, whose pathogenesis remains unclear. Prolonged or aggressive sexual intercourse has been identified as a potential risk factor. We present a case of a 54-year-old man who developed a penile mass following aggressive sexual activity. Diagnosis of superficial dorsal vein thrombosis was made using ultrasound and confirmed by MRI. The patient underwent conservative treatment and abstained from sexual activity. After four weeks, complete resolution of the thrombus was observed. This case emphasizes the importance of healthcare professionals, particularly urologists, in recognizing and managing Penile Mondor\'s disease.
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  • 文章类型: Journal Article
    Mondor疾病的特征是在特定解剖部位发生的急性疼痛性血栓性静脉炎。关于其发病率的数据,临床表现的特点,和课程是不可用的日期。我们研究了2004年至2020年在苏黎世(瑞士)大学医院诊断和随访的患者的Mondor病程。主要研究结果是在临床诊断Mondor疾病时或在1年内诊断出活动性癌症,以及1年全因死亡和复发性Mondor病。我们纳入了45例患者,并将他们分为三个Mondor疾病亚组之一:胸部(n=26),阴茎(n=12),或腋窝(n=7)。中位年龄为39岁(Q1-Q3:30-45岁),44%的患者为男性。在53.8%的胸廓型患者中,手术是引起Mondor病的可能原因,有阴茎位置的人中有41.7%,以及所有有腋窝位置的人。已知的活动性癌症在基线时存在于45名患者中的9名(20%)中。对43例患者进行了一年的随访(中位数为94个月),而其余2例患者的6个月数据可用.在可用的后续行动中,没有患者有新的癌症诊断。总之,五分之一的Mondor病患者在诊断时已知癌症。随访期间,新的癌症诊断率和死亡率可以忽略不计,为这种情况的良好预后提供保证。根据这些初步数据,对于Mondor病患者,除了目前指南推荐的普通人群外,可能不需要延长癌症筛查.
    Mondor disease is characterized by an acute painful thrombophlebitis occurring at specific anatomical sites. Data on its incidence, characteristics of clinical presentation, and course are unavailable to date. We studied the course of Mondor disease in patients diagnosed and followed at the University Hospital Zurich (Switzerland) between 2004 and 2020. The primary study outcomes were a diagnosis of active cancer either at the time of clinical diagnosis of Mondor disease or within 1 year, as well as 1-year all-cause death and recurrent Mondor disease. We included 45 patients and classified them into one of the three Mondor disease subgroups: thoracic (n = 26), penile (n = 12), or axillary (n = 7). The median age was 39 (Q1-Q3: 30-45) years and 44% of patients were men. Surgery was the likely cause of Mondor disease in 53.8% of patients with a thoracic form, 41.7% of those with a penile location, and all of those with an axillary location. Known active cancer was present in nine (20%) of 45 patients at baseline. One-year follow-up was available for 43 patients (median 94 months), whereas 6-month data were available for the remaining two patients. During the available follow-up, no patient had a new diagnosis of cancer. In conclusion, one in five patients with Mondor disease had known cancer at the time of diagnosis. During follow-up, the rate of new cancer diagnosis and death was negligible, providing reassurance about the good prognosis of this condition. Based on these preliminary data, extended cancer screening besides what is recommended by current guidelines for the general population might not be necessary in patients with Mondor disease.
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  • 文章类型: Case Reports
    伦勃朗的芭丝谢巴的模型,巴黎卢浮宫博物馆的一幅著名画作,是他的爱人HendrickjeStoffels.这张照片定期引起医学界的注意,因为Hendrickje似乎患有影响她左乳房的疾病。通常已经提出了乳腺癌。对过去的诊断进行了回顾,并提出了一种新的诊断——蒙多病——基于颜色,对过去诊断的批评,和疾病的深度可以被画家的眼睛感知。最后,这篇文章显示了Bathsheba病与最近观察到的Mondor血栓形成的病例之间的令人信服的比较。
    The model of Rembrandt\'s Bathsheba, a celebrated painting of the Louvre Museum in Paris, was his lover Hendrickje Stoffels. The picture has periodically caught the attention of the medical community because Hendrickje appears to have a condition affecting her left breast. Generally breast cancer has been proposed. The past diagnoses have been reviewed and has been proposed a new one - Mondor\'s disease - based on colour, a critique of past diagnoses, and the depth of the disease to be perceivable by the painters\' eye. Finally, the article shows a convincing comparison between Bathsheba disease and a case of Mondor\'s thrombophebites recently observed.
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  • 文章类型: Case Reports
    背景:先天性耻骨前窦是在下腹部中线发现的罕见异常。新生儿先天性耻骨前窦通常无症状,并且诊断通常是在从耻骨区域的先前存在的孔中自发挤出脓性物质之后的以后生活中实现的。我们介绍了一例先天性耻骨前窦包皮环切术后出现脓性分泌物的病例。一个4岁的高加索男孩出现在我们的泌尿科门诊诊所,他的阴茎背侧远端有脓性分泌物。他有在另一个中心进行包皮环切术的历史,6个月前.他的父母说,尽管使用了各种抗生素,脓性分泌物持续了6个月,孩子在包皮环切术前没有任何抱怨。据报道他的情况是浅背静脉血栓形成,被称为阴茎蒙多病,在以前的医院进行的磁共振成像。体格检查显示,他的阴茎远端有一个小的针孔病变,一个刚性的圆柱形管延伸到阴茎的近侧。我们通过小型血管导管注射对比剂进行了血管造影,并确认了耻骨前窦的诊断。进行了手术探查和长鼻窦,显然在他的耻骨联合前表面以纤维束结束,被发现并切除。
    结论:先天性耻骨前窦手术前,排除阴茎Mondor病和包皮环切术并发症(尤其是感染性并发症)的可能性是非常重要的,这类似于先天性耻骨前窦.
    BACKGROUND: Congenital prepubic sinus is a rare anomaly found in the midline of the lower abdomen. Congenital prepubic sinus is usually asymptomatic in neonates, and a diagnosis is often achieved later in life after spontaneous extrusion of purulent material from the pre-existing hole in the pubic region. We present a case of congenital prepubic sinus presenting with purulent discharge after circumcision. A 4-year-old Caucasian boy presented to our urology out-patient clinic with purulent discharge from the distal part of the dorsum of his penis. He had a history of circumcision performed at a different center, 6 months ago. His parents stated that although various antibiotics were used, the purulent discharge continued for 6 months and the child had no complaints before circumcision. His condition was reported as superficial dorsal venous thrombosis, known as penile Mondor disease, in magnetic resonance imaging that was performed in the previous hospital. A physical examination revealed a small pinhole lesion at the distal part of his penis and a rigid cylindrical tube extending to the proximal side of his penis. We performed fistulography by injecting contrast material through a small angiocatheter and confirmed the diagnosis of prepubic sinus. Surgical exploration was performed and a long sinus, apparently ending as a fibrous tract at the anterior surface of his pubic symphysis, was found and resected.
    CONCLUSIONS: Before congenital prepubic sinus surgery, it is critically important to rule out penile Mondor disease and the possibility of a circumcision complication (especially infective complications) mimicking congenital prepubic sinus.
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  • 文章类型: Journal Article
    Mondor\'s disease (MD) is a rare disease that manifests with a palpable cord-like induration on the body surface. In general, MD is a self-limited, benign thrombophlebitis that resolves in four to eight weeks without any specific treatment. Cases of MD can be roughly categorized into three different groups based on the site of the lesion as follows: original MD of the anterolateral thoracoabdominal wall, penile MD with dorsum and dorsolateral aspects of the penis, and axillary web syndrome with mid-upper arm after axillary surgery. The diagnosis of MD is rather straightforward and based on a physical examinations. However, some case occur \"secondary\" with another underlying disease, including malignancy, a hypercoagulative state, and vasculitis. Therefore, it is critical to identify MD precisely, evaluate any possible underlying disease, and avoid any unnecessary invasive tests or treatment. In this paper, we comprehensively review the clinical characteristics of MD.
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  • 文章类型: Comparative Study
    目的:已知腋窝网综合征(AWS)发生在腋窝清扫术后,并在乳腺癌腋窝前哨淋巴结活检(ASLNB)后报道。然而,ASLNB治疗黑色素瘤后AWS的发生率和结局未知.
    方法:对前瞻性收集的,在14年期间,我们对在一家机构接受黑色素瘤ASLNB治疗的临床淋巴结阴性患者进行了研究,以确定AWS的发病率.与患者有关的特征(年龄和性别),原发性肿瘤(位置,Breslow\的深度),和节点(删除了数字,阳性节率)与AWS的发生相关。
    结果:在接受ASLNB的465名患者中,21人(4.5%)在术后发展AWS。相比之下,该人群中其他并发症的发生率为感染3%,出血1.5%,伤口开裂。8%,淋巴结肿大5%,和淋巴水肿.有或没有AWS的患者在肿瘤厚度方面没有统计学差异,主要位置(上肢vs躯干),平均去除的前哨节点数,SLNB阳性率(10%对12%),患者年龄,或性别。所有AWS病例均通过预期管理解决;没有需要手术干预。
    结论:AWS是黑色素瘤患者ASLNB的显著并发症,发病率高于或高于“标准”并发症。AWS应该,因此,术前讨论ASLNB可能的并发症。传统患者,肿瘤,节点因素不能预测AWS。应告知患者AWS通常对对症治疗有反应,并随时间解决。
    OBJECTIVE: Axillary web syndrome (AWS) is known to occur after axillary dissection and has been reported after axillary sentinel lymph node biopsy (ASLNB) for breast cancer. However, the incidence and outcomes of AWS after ASLNB for melanoma are unknown.
    METHODS: A retrospective review of prospectively collected, clinically node-negative patients undergoing ASLNB for melanoma at a single institution during a 14-year period was conducted to determine the incidence of AWS. Features pertaining to patients (age and gender), primary tumor (location, Breslow\'s depth), and nodes (number removed, positive node rate) were correlated with the occurrence of AWS.
    RESULTS: Of the 465 patients undergoing ASLNB, 21 (4.5%) developed AWS postoperatively. In comparison, the incidence of other complications in this population were infection 3%, bleeding 1.5%, wound dehiscence .8%, lymphocele 5%, and lymphedema .4%. There was no statistical difference between patients with or without AWS in terms of tumor thickness, location of primary (upper extremity vs trunk), average number of sentinel nodes removed, positive SLNB rates (10% vs 12%), patient age, or gender. All cases of AWS resolved with expectant management; none required surgical intervention.
    CONCLUSIONS: AWS is a notable complication of ASLNB for melanoma, with an incidence as high or higher than \"standard\" complications. AWS should, therefore, be included in the preoperative discussion of possible complications of ASLNB. Traditional patient, tumor, and nodal factors are not predictive of AWS. Patients should be counseled that AWS usually responds to symptomatic treatment and resolves with time.
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  • 文章类型: Journal Article
    背景:蒙多病(MD),文献中很少报道胸腹静脉及其汇合的浅表血栓性静脉炎。腹上静脉是受影响最大的血管,但也已描述了腹下血管或其分支的受累。文献中没有关于治疗的普遍共识,但大多数作者建议使用非甾体抗炎药(NSAIDs)进行对症治疗。
    方法:我们报告一例马拉松运动员出现右髂窝疼痛,类似急性阑尾炎的临床症状。病史和计算的Alvarado评分不赞成急性阑尾炎。这种情况激发了多种调查,我们最终得出了MD的诊断。
    结论:急性阑尾炎(AA)是引起外科急症的最常见原因,也是全世界进行紧急腹部手术的最常见适应症之一。在某些情况下,尽管美国,右下腹疼痛仍不清楚,CT扫描,排除泌尿科和妇科原因,因此,我们需要考虑一些罕见的病理,如MD。
    结论:MD在乳腺病变的鉴别诊断中经常被提及,但在腹痛评估中很少被提及。当临床表现不明确且排除急性阑尾炎时,在右下腹疼痛的鉴别诊断中应提及。对MD的认识可以避免误诊,并通过节省不必要的成像来减少额外的费用。
    BACKGROUND: Mondor disease (MD), a superficial thrombophlebitis of the thoraco-epigastric veins and their confluents is rarely reported in the literature. The superior epigastric vein is the most affected vessel but involvement of the inferior epigastric vessels or their branches have also been described. There is no universal consensus on treatment in the literature but most authors suggest symptomatic treatment with non-steroid anti-inflammatory drugs (NSAIDs).
    METHODS: We report the case of a marathon runner who presented with right iliac fossa pain mimicking the clinical symptomatology of an acute appendicitis. The history and the calculated Alvarado score were not in favor of an acute appendicitis. This situation motivated multiple investigations and we finally arrived at the diagnosis of MD.
    CONCLUSIONS: Acute appendicitis (AA) is the most common cause of surgical emergencies and one of the most frequent indications for an urgent abdominal surgical procedure around the world. In some cases, right lower quadrant pain remains unclear in spite of US, CT scan, and exclusion of urological and gynecological causes, thus we need to think of some rare pathologies like MD.
    CONCLUSIONS: MD is often mentioned in the differential diagnosis of breast pathologies but rarely in abdominal pain assessment. It should be mentioned in the differential diagnosis of the right lower quadrant pain when the clinical presentation is unclear and when acute appendicitis has been excluded. Awareness of MD can avoid misdiagnosis and decrease extra costs by sparing unnecessary imaging.
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