Low-temperature plasma radiofrequency ablation

  • 文章类型: Journal Article
    目的:口状舌管囊肿是临床上较为少见的疾病。本文对7例患者的诊治过程进行综述,结合以往文献报道,探讨口内甲状舌管囊肿的临床诊治特点。
    方法:对2017年1月至2024年1月大连市中心医院耳鼻咽喉科收治的7例口内甲状舌管囊肿进行回顾性分析。这些病例是按性别记录的,年龄,症状,身体体征,放射学检查,手术方法,术后并发症。所有病例均得到随访,并记录最新的随访结果。
    结果:在7例中,6例患者在手术前接受了喉镜和放射学检查,1名儿童在手术中被发现有囊肿。所有病例均诊断为口内甲状舌管囊肿,并采用等离子射频手术治疗。患者均无术后并发症,出院后6个月随访未见复发。
    结论:口状甲状舌管囊肿临床少见。临床上重视其鉴别诊断,手术前需要仔细检查图像。低温等离子射频冷冻消融术不仅创伤小,恢复快,而且并发症少,复发率低。是一种安全有效的治疗方法,值得临床推广。
    方法:第3级。
    OBJECTIVE: Intraoral thyroglossal duct cyst is a relatively rare clinical disease. This article reviews the diagnosis and treatment process of 7 patients and explores the clinical characteristics of diagnosis and treatment of intraoral thyroglossal duct cyst in combination with past literature reports.
    METHODS: A retrospective analysis was conducted on 7 cases of intraoral thyroglossal duct cyst admitted to the Otolaryngology ward of Dalian Municipal Central Hospital from January 2017 to January 2024. The cases were recorded in terms of gender, age, symptoms, physical signs, radiological examinations, surgical methods, and postoperative complications. All cases were followed up, and the latest follow-up results were recorded.
    RESULTS: Among the 7 cases, 6 patients underwent laryngoscopic and radiological examinations before surgery, and 1 child was found to have a cyst during surgery. All cases were diagnosed with intraoral thyroglossal duct cyst and treated with plasma radiofrequency surgery. None of the patients had postoperative complications, and no recurrence was found in the six-month follow-up after discharge.
    CONCLUSIONS: Intraoral thyroglossal duct cyst is rare in clinical practice. It is important to pay attention to its differential diagnosis clinically, and careful review of images is required before surgery. Cryoablation with low-temperature plasma radiofrequency is not only minimally invasive and has a quick recovery but also has few complications and a low recurrence rate. It is a safe and effective treatment method that is worthy of clinical promotion.
    METHODS: Level 3.
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    文章类型: Journal Article
    目的:本研究旨在确定CO2激光联合低温等离子射频消融(LPRA)对老年早期声门喉癌(GLC)患者吞咽功能和预后的影响。
    方法:对2013年5月至2015年9月大庆油田总医院收治的115例老年早期GLC患者的临床资料进行回顾性分析。根据不同的治疗方案将这些患者分为研究组或对照组。将56例采用CO2激光切除的患者分为对照组。59例采用CO2激光联合LPRA治疗。住院,术后疼痛,粘膜恢复评分,术后并发症,吞咽功能,声乐功能,比较两组5年复发率。采用多因素logistic回归分析患者5年复发的独立危险因素。
    结果:研究组住院时间明显优于对照组,术后疼痛,粘膜恢复评分(P<0.05),两组术后并发症发生率比较差异无统计学意义(P>0.05)。治疗后,研究组吞咽功能和发声功能优于对照组,两组5年复发率相似(P=0.288)。多因素logistic回归分析确定年龄较高,较低的分化,和累积前连合的存在是复发的独立危险因素。
    结论:CO2激光联合LPRA治疗老年早期GLC的临床疗效较高,之后,患者吞咽功能和发声功能迅速恢复,但加入LPRA的长期好处并不明显。
    OBJECTIVE: This study was designed to determine the effect of CO2 laser combined with low-temperature plasma radiofrequency ablation (LPRA) on swallowing function and prognosis in elderly patients with early glottic laryngeal cancer (GLC).
    METHODS: The clinical data of 115 elderly patients with early GLC treated in General Hospital of Daqing Oil Field from May 2013 to September 2015 were retrospectively analyzed. These patients were assigned to a research group or control group according to different therapeutic regimen. Totally 56 cases treated with CO2 laser resection were assigned to the control group, and 59 cases treated with CO2 laser combined with LPRA were assigned to the research group. The hospital stay, postoperative pain, mucosal recovery score, postoperative complications, swallowing function, vocal function, and 5-year recurrence rate were compared between the two groups. Independent risk factors for 5-year recurrence in patients were analyzed by multivariate logistic regression.
    RESULTS: The research group was significantly superior to the control group in terms of hospital stay, postoperative pain, and mucosal recovery score (P<0.05), and the postoperative complication rate was not significantly different between the two groups (P>0.05). After treatment, the research group showed better swallowing function and vocal function than the control group, and the 5-year recurrence rate of the two groups was similar (P=0.288). Multivariate logistic regression analysis identified higher age, lower differentiation, and presence of a cumulative anterior commissure as independent risk factors for recurrence.
    CONCLUSIONS: CO2 laser combined with LPRA can provide relatively high clinical efficacy for early GLC in the elderly, after which patients\' swallowing function and vocal function recover quickly, but the long-term benefit of adding LPRA is not evident.
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  • 文章类型: Journal Article
    比较低温等离子射频消融和部分喉切除术治疗早期声门癌的疗效。
    分析2019年6月至2021年1月我院收治的80例早期声门癌患者的临床资料。根据干预类型将患者分为两组。40例患者接受喉部分切除术(对照组),40例患者接受低温等离子射频消融术(观察组)。手术指标,住院时间,术后并发症,比较两组患者术后疼痛视觉模拟量表(VAS)评分。术后应激反应指标,临床疗效,对两组患者术后恢复情况进行对比分析。
    操作时间,住院,术中出血,观察组术后并发症发生率明显低于对照组(P<0.05)。术后疼痛VAS评分,观察组丙二醛(MDA)、谷胱甘肽(GSH)水平明显低于对照组(P<0.05),而硝基酪氨酸(3-NT)和超氧化物歧化酶(SOD)水平明显高于对照组(P<0.05)。经过一年的随访,观察组发音功能优良率(95%)明显高于对照组(75%)(P<0.05)。
    低温等离子射频消融术治疗早期声门癌创伤小,操作时间短,出血少,住院时间短,术后应激反应率低。与喉部分切除术相比,安全性较高,术后声带功能恢复较好。
    UNASSIGNED: To compare the therapeutic effects of low-temperature plasma radiofrequency ablation and partial laryngectomy in the treatment of early glottis carcinoma.
    UNASSIGNED: Clinical data of 80 patients with early glottis carcinoma treated in our hospital from June 2019 to January 2021 were analyzed. Patients were retrospectively divided into two groups based on the type of intervention. Forty patients received partial laryngectomy (Control group) and 40 patients received low-temperature plasma radiofrequency ablation (Observation group). Surgical indexes, length of hospital stay, postoperative complications, and visual analog scale (VAS) score of postoperative pain of patients in the two groups were compared. Postoperative stress response indexes, clinical efficacy, and postoperative recovery in two groups were compared and analyzed.
    UNASSIGNED: The operation time, hospital stay, intraoperative bleeding, and the incidence of postoperative complications in the observation group were significantly lower than those in the Control group (P<0.05). The postoperative pain VAS scores, Levels of malondialdehyde (MDA) and glutathione (GSH) in the observation group were significantly lower than those in the control group (P<0.05), while the level of nitro tyrosine (3-NT) and superoxide dismutase (SOD) were significantly higher than that in the control group (P<0.05). After a one-year follow-up, the excellent and good rate of pronunciation function in the observation group (95%) was significantly higher than control group (75%) (P<0.05).
    UNASSIGNED: Low-temperature plasma radiofrequency ablation in the treatment of early glottis carcinoma is associated with less trauma, short operation time, less bleeding, short hospital stay and low postoperative stress reaction rate. Compared with partial laryngectomy, it has higher safety and better postoperative vocal cord function recovery.
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  • 文章类型: Journal Article
    UNASSIGNED:本研究评估了低温等离子消融背根神经节(DRG)联合选择性脊神经阻滞对急性或亚急性带状疱疹相关性神经痛(ZRN)患者的镇痛疗效和心理反应。
    UNASSIGNED:将90例ZRN患者随机均分为三组。A组采用C臂引导选择性脊神经阻滞(C-SSVB)治疗,B组使用C-SSVB和脉冲射频(PRF),和C组使用C-SSVB和低温等离子体消融的DRG。使用视觉模拟量表(VAS)检查结果。采用焦虑自评量表(SAS)和抑郁自评量表(SDS)对患者的焦虑、抑郁进行评价。使用匹兹堡睡眠质量指数(PSQI)和术后满意度量表评估生活质量。此外,收集有关不良事件和药物使用率的数据.
    未经批准:90例患者符合本研究的条件。三种治疗方法在同一时间点降低了VAS评分,A组和B组之间无显著差异;然而,B组的VAS评分往往较低。相对而言,与其他两组相比,C组治疗后第1天和第1个月的VAS评分明显降低。在SAS下降方面,SDS和PSQI得分,所有这三种治疗方法都改善了焦虑,患者的抑郁和睡眠质量。此外,在所有时间点,与A组相比,C组的焦虑显著减轻。然而,在治疗相关的不良事件,主要集中在手术部位的穿刺疼痛,三组之间没有统计学上的显著差异,皮肤麻木和药物使用率。
    UNASSIGNED:DRG的C-SSVB和LTPRA将被认为是ZRN患者的有希望的治疗选择,如果这些结果可以在进一步验证后得到证实。
    UNASSIGNED: This study evaluated the analgesic efficacy and psychological response of low-temperature plasma ablation of dorsal root ganglion (DRG) combined with selective spinal nerve block in patients with acute or subacute zoster-related neuralgia (ZRN).
    UNASSIGNED: Totally 90 ZRN patients were randomly and evenly divided into three groups. Treatment was given to Group A using C arm-guided selective spinal nerve block (C-SSVB), Group B using C-SSVB and pulsed radiofrequency (PRF), and Group C using C-SSVB and low-temperature plasma ablation of the DRG. The outcomes were examined using the Visual Analog Scale (VAS). Anxiety and depression of patients were evaluated using the Self-rating Anxiety Scale (SAS) and Self-rating Depression Scale (SDS). Quality of life was assessed using the Pittsburgh Sleep Quality Index (PSQI) and postoperative Satisfaction scale. In addition, data on adverse events and medication usage rates were collected.
    UNASSIGNED: The 90 patients were eligible for this study. The three treatments reduced VAS scores with no significant difference between groups A and B at the same time points; however, group B tended to have numerically lower VAS scores. Comparatively, group C had significantly reduced VAS scores on day 1 and 1 month after treatment compared with the other two groups. In terms of the decreasing SAS, SDS and PSQI scores, all the three treatments improved the anxiety, depression and sleep quality of the patients. In addition, significant alleviation in anxiety was found in group C compared with group A at all- time points. However, there was no statistically significant difference among the three groups in treatment-related adverse events that mainly focused on puncture pain at the surgical-site, skin numbness and medication usage rates.
    UNASSIGNED: C-SSVB and LTPRA of DRG will be considered as a promising treatment option for ZRN patients if those results can be confirmed after further validation.
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  • DOI:
    文章类型: Journal Article
    目的:探讨顺铂注射液联合低温等离子射频消融术对晚期喉癌患者临床疗效及血清survivin水平的影响。
    方法:选取我院2018年1月至2020年6月收治的42例局部晚期喉癌患者作为研究队列,根据每位患者的用药情况分为对照组(21例)和治疗组(21例)。对照组采用喉镜下CO2激光切除联合顺铂注射治疗,观察组患者采用低温等离子射频消融术联合顺铂注射治疗。观察两组临床疗效及WHOQOL-BREF评分,肿瘤标志物水平,比较血清survivin水平。
    结果:治疗后,对照组的ORR和CBR分别为33.3%和61.9%,分别,显著低于观察组的66.7%和90.5%(P<0.05)。观察组的生理,心理,与社会关系维度得分显著高于对照组相应得分(P<0.05)。观察组血清肿瘤标志物CA72-4、CA19-9、SCC-Ag水平均低于对照组(P<0.05)。观察组血清survivin水平低于对照组(P<0.05)。结论顺铂注射联合低温等离子射频消融术治疗局部晚期喉癌疗效显著。它可以改善患者的生活质量,降低体内的肿瘤标志物水平,并抑制血清存活素水平。
    OBJECTIVE: To investigate the effect of cisplatin injections combined with low-temperature plasma radiofrequency ablation on the clinical efficacy and serum survivin levels in advanced laryngeal cancer patients.
    METHODS: A total of 42 patients with locally advanced laryngeal cancer treated in our hospital from January 2018 to June 2020 were recruited as the study cohort and placed in a control group (21 cases) or a treatment group (21 cases) according to the medication administered to each patient. The patients in the control group were treated with CO2 laser resections under laryngoscopy combined with cisplatin injections, and the patients in the observation group were treated with low-temperature plasma radiofrequency ablation combined with cisplatin injections. The clinical efficacies in the two groups were observed and the WHOQOL-BREF scores, tumor marker levels, and serum survivin levels were compared.
    RESULTS: After the treatment, the ORR and CBR in the control group were 33.3% and 61.9%, respectively, levels that were significantly lower than the 66.7% and 90.5% in the observation group (P<0.05). The observation group\'s physiological, psychological, and social relations dimension scores were significantly higher than the corresponding scores in the control group (P<0.05). The tumor markers in the observation group were significantly lower in the serum CA72-4, CA19-9, and SCC-Ag levels than they were in the control group (P<0.05). The observation group exhibited lower serum survivin levels than the control group (P<0.05). Conclusion Cisplatin injections combined with low-temperature plasma radiofrequency ablation has a significant effect on the treatment of locally advanced laryngeal cancer. It can improve patients\' quality of life, reduce the tumor marker levels in the body, and inhibit the serum survivin levels.
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  • 文章类型: Journal Article
    尽管蝶腭神经节(SPG)被认为是治疗丛集性头痛(CH)的潜在部位,SPG的最佳技术仍有待确定。低温等离子射频消融(LTPRA)已被提议作为几种神经性疼痛疾病的替代疗法。
    评估SPG的LTPRA治疗慢性和发作性CH的效果。
    患有CH的患者,在SPG阻滞后实现了暂时的疼痛缓解,对2015年1月至2017年10月期间使用LTPRA治疗的患者进行了回顾.包括76例患者:50例患有发作性CH,其余26例患有慢性CH。主要结果是临床改善率,定义为1天部分和完全疼痛缓解结果的百分比,12个月,术后24个月随访。
    临床改善率为92.3%,慢性CH分别为92.3%和73.1%和73.1%,每个随访时间点的偶发性CH分别为84%和68%,分别。3例慢性CH患者和7例发作性CH患者术后疼痛无缓解。2例眼睑下垂,其中1人在3个月随访时痊愈,但另1人在24个月随访中未痊愈.术中、术后无严重并发症发生。
    LTPRA可以被认为是治疗慢性和发作性CH患者的有效和替代手术方式,基于SPG块。
    UNASSIGNED: Although the sphenopalatine ganglion (SPG) has been considered a site of therapeutic potential for cluster headache (CH), the optimal technique of SPG is still to be determined. Low-temperature plasma radiofrequency ablation (LTPRA) has been proposed as an alternative treatment for several neuropathic pain diseases.
    UNASSIGNED: To evaluate the effect of LTPRA of SPG in treating chronic and episodic CH.
    UNASSIGNED: The patients with CH, who achieved temporary pain relief following SPG block, treated using LTPRA between January 2015 and October 2017 were reviewed. Seventy-six patients were included: 50 patients suffered from episodic CH and the remaining 26 patients from chronic CH. The primary outcomes were clinical improvement rate, defined as the percentage of partial and complete pain relief results at 1 day, 12 months, and 24 months of follow-up after the operation.
    UNASSIGNED: Clinical improvement rates were 92.3%, 92.3% and 73.1% in chronic CH and 73.1%, 84% and 68% in episodic CH at each follow-up time point, respectively. 3 chronic CH patients and 7 episodic CH patients showed no pain relief after the operation. Drooping eyelids were found in 2 cases, one recovered at the 3-month follow-up but another one did not in the 24-month follow-up. No serious complications occurred intraoperatively or postoperatively.
    UNASSIGNED: LTPRA can be considered an effective and alternative surgical modality in treating patients with chronic and episodic CH, based on SPG block.
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  • 文章类型: Journal Article
    UNASSIGNED: Cluster headache (CH) is a refractory headache. Low-temperature plasma radiofrequency ablation is a relatively novel technique with promising applications in neuropathic pain. It may improve the treatment of CH.
    UNASSIGNED: To evaluate the efficacy and safety of sphenopalatine ganglion-targeted low-temperature plasma radiofrequency ablation in the treatment of patients with refractory CH.
    UNASSIGNED: A retrospective cohort study including seventy-five patients with refractory cluster headache who underwent computed tomography (CT)-guided sphenopalatine ganglion-targeted low-temperature plasma radiofrequency ablation between January 2015 and December 2017 at the Beijing Xuanwu Hospital was conducted.
    UNASSIGNED: Effective pain relief rate 3 months after the procedure was 96% with 40 (53.3%) patients achieving complete relief; 32 (42.7%) patients obtained partial relief and 3 (4%) patients showed no relief. The effective pain relief rate two years after the procedure remained as high as 85.3% with 29 (38.6%) achieving complete relief, 35 (46.7%) partial relief and 11 (14.7%) no relief. The procedure proved equally effective for both episodic and chronic cluster headache. Complications including facial numbness, masseter weakness, facial hypoesthesia and cheek hematoma were observed, but all were mild and disappeared within 6 months.
    UNASSIGNED: CT-guided low-temperature plasma radiofrequency ablation is an effective and safe strategy for refractory cluster headache. For patients who have not responded to conservative treatment, this minimally invasive intervention is a reliable alternative.
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  • 文章类型: Clinical Trial
    To evaluate the effectiveness and safety of low-temperature plasma radiofrequency ablation (coblation) and Nd:YAG laser in treating recurrent nasolacrimal duct obstruction. A prospective study was performed on patients who agreed to be treated with coblation or Nd:YAG laser for recurrent nasolacrimal duct obstruction after failed lacrimal Nd:YAG laser combined with silicone intubation. The visual analogue scale (VAS) pain grade was assessed at baseline, immediately, and 3 and 7 days after surgery. The degree of watering, lacrimal passage irrigation, and complications were also evaluated 1 week and 1, 3, and 6 months after surgery. Ninety-five patients who met the criteria for recurrent nasolacrimal duct obstruction from February 2018 to February 2019 were included in this study, with 46 patients receiving coblation and 49 patients Nd:YAG laser. The intraoperative and postoperative (3 days after surgery) VAS pain grades of the patients who received coblation were significantly lower than those who received Nd:YAG laser (P < 0.001). The number of patients in the coblation group who achieved complete clinical relief (no epiphora symptoms with fluent lacrimal passage irrigation) was significantly larger than that in the lacrimal Nd:YAG laser group at 1, 3, and 6 months after surgery (P = 0.033, P = 0.006, P = 0.003, respectively). During the follow-up period, there were no unexpected complications in either group. Compared with Nd:YAG laser, coblation performed well in alleviating pain and maintaining sustained disease relief and may therefore be an alternative to conventional laser or dacryocystorhinostomy surgery in the management of recurrent nasolacrimal duct obstruction.
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  • 文章类型: Case Reports
    To evaluate the feasibility and effectiveness of using endoscopic low-temperature plasma radiofrequency ablation (RFA) for treatment of laryngeal plexiform neurofibromatosis-1 (NF-1). An infant diagnosed as laryngeal plexiform NF-1 based on a detailed medical history, as well as physical, laboratory, and pathological examinations, was treated under general anesthesia with low-temperature plasma RFA in combination with a self-retaining laryngoscope and high definition camera system.The laryngeal plexiform NF-1 tumor was successfully excised using endoscopic low-temperature plasma RFA without complications. Following surgery, the infant displayed an uneventful recovery and no disease recurrence during a 2-year follow-up period. low-temperature plasma RFA is a feasible and effective method for treating laryngeal plexiform NF-1, and has advantages of producing minimal bleeding, providing complete removal of the tumor, and causing only slight degrees of trauma and postoperative tissue reaction.
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