PDF(Pubmed)
Abstract：
UNASSIGNED: This study evaluated the analgesic efficacy and psychological response of low-temperature plasma ablation of dorsal root ganglion (DRG) combined with selective spinal nerve block in patients with acute or subacute zoster-related neuralgia (ZRN).
UNASSIGNED: Totally 90 ZRN patients were randomly and evenly divided into three groups. Treatment was given to Group A using C arm-guided selective spinal nerve block (C-SSVB), Group B using C-SSVB and pulsed radiofrequency (PRF), and Group C using C-SSVB and low-temperature plasma ablation of the DRG. The outcomes were examined using the Visual Analog Scale (VAS). Anxiety and depression of patients were evaluated using the Self-rating Anxiety Scale (SAS) and Self-rating Depression Scale (SDS). Quality of life was assessed using the Pittsburgh Sleep Quality Index (PSQI) and postoperative Satisfaction scale. In addition, data on adverse events and medication usage rates were collected.
UNASSIGNED: The 90 patients were eligible for this study. The three treatments reduced VAS scores with no significant difference between groups A and B at the same time points; however, group B tended to have numerically lower VAS scores. Comparatively, group C had significantly reduced VAS scores on day 1 and 1 month after treatment compared with the other two groups. In terms of the decreasing SAS, SDS and PSQI scores, all the three treatments improved the anxiety, depression and sleep quality of the patients. In addition, significant alleviation in anxiety was found in group C compared with group A at all- time points. However, there was no statistically significant difference among the three groups in treatment-related adverse events that mainly focused on puncture pain at the surgical-site, skin numbness and medication usage rates.
UNASSIGNED: C-SSVB and LTPRA of DRG will be considered as a promising treatment option for ZRN patients if those results can be confirmed after further validation.
UNASSIGNED: Totally 90 ZRN patients were randomly and evenly divided into three groups. Treatment was given to Group A using C arm-guided selective spinal nerve block (C-SSVB), Group B using C-SSVB and pulsed radiofrequency (PRF), and Group C using C-SSVB and low-temperature plasma ablation of the DRG. The outcomes were examined using the Visual Analog Scale (VAS). Anxiety and depression of patients were evaluated using the Self-rating Anxiety Scale (SAS) and Self-rating Depression Scale (SDS). Quality of life was assessed using the Pittsburgh Sleep Quality Index (PSQI) and postoperative Satisfaction scale. In addition, data on adverse events and medication usage rates were collected.
UNASSIGNED: The 90 patients were eligible for this study. The three treatments reduced VAS scores with no significant difference between groups A and B at the same time points; however, group B tended to have numerically lower VAS scores. Comparatively, group C had significantly reduced VAS scores on day 1 and 1 month after treatment compared with the other two groups. In terms of the decreasing SAS, SDS and PSQI scores, all the three treatments improved the anxiety, depression and sleep quality of the patients. In addition, significant alleviation in anxiety was found in group C compared with group A at all- time points. However, there was no statistically significant difference among the three groups in treatment-related adverse events that mainly focused on puncture pain at the surgical-site, skin numbness and medication usage rates.
UNASSIGNED: C-SSVB and LTPRA of DRG will be considered as a promising treatment option for ZRN patients if those results can be confirmed after further validation.
摘要：
UNASSIGNED：本研究评估了低温等离子消融背根神经节（DRG）联合选择性脊神经阻滞对急性或亚急性带状疱疹相关性神经痛（ZRN）患者的镇痛疗效和心理反应。
UNASSIGNED：将90例ZRN患者随机均分为三组。A组采用C臂引导选择性脊神经阻滞（C-SSVB）治疗，B组使用C-SSVB和脉冲射频（PRF），和C组使用C-SSVB和低温等离子体消融的DRG。使用视觉模拟量表(VAS)检查结果。采用焦虑自评量表(SAS)和抑郁自评量表(SDS)对患者的焦虑、抑郁进行评价。使用匹兹堡睡眠质量指数（PSQI）和术后满意度量表评估生活质量。此外,收集有关不良事件和药物使用率的数据.
未经批准：90例患者符合本研究的条件。三种治疗方法在同一时间点降低了VAS评分，A组和B组之间无显著差异；然而，B组的VAS评分往往较低。相对而言,与其他两组相比，C组治疗后第1天和第1个月的VAS评分明显降低。在SAS下降方面，SDS和PSQI得分，所有这三种治疗方法都改善了焦虑，患者的抑郁和睡眠质量。此外,在所有时间点，与A组相比，C组的焦虑显著减轻。然而,在治疗相关的不良事件，主要集中在手术部位的穿刺疼痛，三组之间没有统计学上的显著差异，皮肤麻木和药物使用率。
UNASSIGNED：DRG的C-SSVB和LTPRA将被认为是ZRN患者的有希望的治疗选择，如果这些结果可以在进一步验证后得到证实。
UNASSIGNED：将90例ZRN患者随机均分为三组。A组采用C臂引导选择性脊神经阻滞（C-SSVB）治疗，B组使用C-SSVB和脉冲射频（PRF），和C组使用C-SSVB和低温等离子体消融的DRG。使用视觉模拟量表(VAS)检查结果。采用焦虑自评量表(SAS)和抑郁自评量表(SDS)对患者的焦虑、抑郁进行评价。使用匹兹堡睡眠质量指数（PSQI）和术后满意度量表评估生活质量。此外,收集有关不良事件和药物使用率的数据.
未经批准：90例患者符合本研究的条件。三种治疗方法在同一时间点降低了VAS评分，A组和B组之间无显著差异；然而，B组的VAS评分往往较低。相对而言,与其他两组相比，C组治疗后第1天和第1个月的VAS评分明显降低。在SAS下降方面，SDS和PSQI得分，所有这三种治疗方法都改善了焦虑，患者的抑郁和睡眠质量。此外,在所有时间点，与A组相比，C组的焦虑显著减轻。然而,在治疗相关的不良事件，主要集中在手术部位的穿刺疼痛，三组之间没有统计学上的显著差异，皮肤麻木和药物使用率。
UNASSIGNED：DRG的C-SSVB和LTPRA将被认为是ZRN患者的有希望的治疗选择，如果这些结果可以在进一步验证后得到证实。
