背景：炎性肌纤维母细胞瘤（IMT）是罕见的间充质肿瘤，病因不明，恶性潜能不确定，影响所有年龄组。IMT最常见于肺部；尽管它们确实发生在各种其他器官中。据报道，肠系膜有IMT，头部和颈部,网膜,腹膜后,四肢,泌尿生殖道,and,极少,在胃里。关于IMT的流行病学数据很少，在某种程度上,由于缺乏国家和国际注册管理机构。
方法：这是一例10个月大的女孩在4个月内出现发热和体重减轻的临床症状的病例报告。该患者最初被诊断患有不明原因的发热综合征。然而,经过进一步调查,发现了胃IMT,患者需要左肝切除术和胃大部切除术并进行Roux-en-Y重建术。
结论：在儿科人群中，临床发现通常是非特异性的。基于这个案例研究,我们的结论是，在有明显肿块的儿童中，IMT应始终被视为诊断选项。
BACKGROUND: Inflammatory Myofibroblastic Tumors (IMTs) are rare mesenchymal tumors of unclear etiology and uncertain malignant potential that affect all age groups. IMTs are most often found in the lungs; although they do occur in a variety of other organs. IMTs have been reported in the mesentery, head and neck, omentum, retroperitoneum, limbs, genitourinary tract, and, extremely rarely, in the stomach. There is scant epidemiological data on IMTs, in part, due to the absence of national and international registries.
METHODS: This is a case report of a 10-month-old girl who presented with clinical signs of fever and weight loss over a period of four months. The patient was initially diagnosed with a febrile syndrome of unknown origin. However, upon further investigation, a Gastric IMT was found, and the patient required a left hepatectomy and subtotal gastrectomy with Roux-en-Y reconstruction.
CONCLUSIONS: In the pediatric population clinical findings are often nonspecific. Based on this case study, we conclude that, in children with palpable masses, IMT should always be considered as a diagnostic option.
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