■验证白蛋白衍生的中性粒细胞对淋巴细胞(ALB-dNLR)评分在诊断70岁以上内科住院患者营养不良中的作用。
■这是一项回顾性的横断面研究,涉及来自14家中国医院的7个科室。计算ALB-dNLR评分,在倾向评分匹配(PSM)后,比较ALB-dNLR评分为阳性和阴性的组间结果.之后,在PSM后使用全球领导力倡议营养不良(GLIM)标准诊断的营养不良患者中,比较接受营养支持和未接受营养支持的组的结局.
■在10184例病例中,6165是合格的。ALB-dNLR评分阳性组2200例。PSM之后,分析了1458对,显示住院死亡率较低(0.8%与2.1%,p=0.005)和较低的医院感染率(5.9%vs.11.0%,在ALB-dNLR评分阴性组中p<0.001)。在营养不良的患者中,在PSM后分析259对。它在死亡率方面显示出更好的结果(0.8%vs.3.5%,p=0.033),医院感染率(5.4%vs.15.4%,p<0.001),住院时间(LOS)(13.8±10.3vs.18.4±14.1,p<0.001),和医院总费用(3315.3±2946.4vs.4795.3±4198.2,p<0.001)在支持组中。在以ALB-dNLR评分为唯一病因标准的营养不良患者中,计算了94对。它在死亡率方面显示出更好的结果(0.0%vs.6.4%,p=0.029),医院感染率(7.4%vs.18.1%,p=0.029),LOS(13.7±8.3vs.19.8±15.2,p=0.001),和医院总费用(3379.3±2955.6vs.4471.2±4782.4,p=0.029)在支持组中。
ALB-dNLR评分已被验证用于预测70岁以上内科住院患者的住院死亡率。根据GLIM标准诊断并使用ALB-dNLR评分的营养不良患者可能会受益于营养支持。
UNASSIGNED: To validate the role of the albumin-derived neutrophil-to-lymphocyte (ALB-dNLR) score in diagnosing malnutrition in medical inpatients over 70 years old.
UNASSIGNED: This is a retrospective cross-sectional study involving 7 departments from 14 Chinese hospitals. The ALB-dNLR score was calculated, and outcomes between groups with positive and negative ALB-dNLR scores were compared after propensity score matching (PSM). Afterwards, the outcomes were compared between the groups receiving nutrition support and those not receiving support among malnourished patients diagnosed using the Global Leadership Initiative Malnutrition (
GLIM) criteria after PSM.
UNASSIGNED: Out of 10,184 cases, 6165 were eligible. 2200 cases were in the positive ALB-dNLR score group. After PSM, 1458 pairs were analyzed, showing lower in-hospital mortality (0.8 % vs. 2.1 %, p = 0.005) and a lower nosocomial infection rate (5.9 % vs. 11.0 %, p < 0.001) in the negative ALB-dNLR score group. In malnourished patients, 259 pairs were analyzed after PSM. It showed better outcomes in mortality (0.8 % vs. 3.5 %, p = 0.033), nosocomial infection rate (5.4 % vs. 15.4 %, p < 0.001), length of stay (LOS) (13.8 ± 10.3 vs. 18.4 ± 14.1, p < 0.001), and total hospital cost (3315.3 ± 2946.4 vs. 4795.3 ± 4198.2, p < 0.001) in the support group. In malnourished patients with ALB-dNLR score as the sole etiological criterion, 94 pairs were calculated. It showed better outcomes in mortality (0.0 % vs. 6.4 %, p = 0.029), nosocomial infection rate (7.4 % vs. 18.1 %, p = 0.029), LOS (13.7 ± 8.3 vs. 19.8 ± 15.2, p = 0.001), and total hospital cost (3379.3 ± 2955.6 vs. 4471.2 ± 4782.4, p = 0.029) in the support group.
UNASSIGNED: The ALB-dNLR score was validated to predict in-hospital mortality in medical inpatients over 70 years old. Malnutrition patients diagnosed by the
GLIM criteria and using the ALB-dNLR score might benefit from nutrition support.