Coupling mechanism

耦合机制
  • 文章类型: Journal Article
    中国土地政策的几个重大变化,经济体制,和发展战略促进了农村模式和城乡关系的不断转变。城乡互动的不断深化,导致乡村地域功能日趋复杂,强调了地域多功能机制在中国农村发展动态过程中的重要性。然而,当前农村发展模式的选择缺乏将农村地区的功能机制与发展环境要素相结合的综合思维。在本文中,我们定义和识别了甘肃省农村地区的功能,中国,通过分析乡村区域功能与“乡村振兴”战略的互动机制,分析并构建了乡村发展模式。我们发现,在“乡村振兴”的控制下,“一个可持续发展的工具,农村正在不断发展成为一个多功能的综合体,其开发模式应根据功能变化进行动态调整。最后,总结了农村区域多功能系统的一般演化周期,并试图从中国农村区域功能的角度推断“乡村振兴”的动态发展型村庄类型分类过程。
    Several major changes in China\'s land policy, economic system, and development strategy have contributed to the continuous transformation of rural patterns and urban-rural relations. The deepening of urban-rural interaction has led to an increasing complexity of rural territorial functions, and the importance of territorial multifunctional mechanisms in the dynamic process of rural development in China has been highlighted. However, the current choice of a rural development model lacks comprehensive thinking that combines the functional mechanisms of rural areas with the elements of the development environment. In this paper, we define and identify the functions of rural areas in Gansu Province, China, and analyze and construct a rural development model by analyzing the interaction between the mechanisms of rural regional functions and the \"rural revitalization\" strategy. We find that under the control of \"rural revitalization,\" a sustainable development tool, the countryside is constantly developing into a multifunctional complex, and its development mode should be dynamically adjusted according to functional changes. Finally, we summarize the general evolutionary cycle of the multifunctional system of rural regions and attempt to extrapolate the dynamic developmental village type classification process of \"rural revitalization\" from the perspective of rural regional functions in China.
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  • 文章类型: Journal Article
    AC-DC配电网段中的电能质量之间的相互作用有助于整个网络中电能质量异常的分布式传播。重点研究光伏多功能并网逆变器(PVMFGCI),本研究深入探讨了一种优化区域电能质量的协同治理策略。最初,该分析剖析了与交流子网电压中的谐波和不对称相对应的直流纹波产生机制。随后,提出了一种交流侧电能质量综合控制区域划分策略,基于光伏控制领域和电能质量分类的见解,考虑光伏治理资源。Further,基于PVMFGCI的治理能力和剩余容量,建立了结合并网变流器主动优化潜力的治理资源协同分配模型。最后,通过基于MATLAB的实例分析,验证了该方法的有效性。
    The interactions between power quality in the AC-DC distribution network segments contribute to the distributed propagation of power quality anomalies throughout the entire network. Focusing on the photovoltaic multifunctional grid-connected inverter (PVMFGCI), this study deeply explores a collaborative governance strategy for optimizing regional power quality. Initially, the analysis dissects the DC ripple generation mechanism corresponding to harmonics and asymmetry in AC subnetwork voltages. Subsequently, a strategy is proposed for partitioning comprehensive control regions for AC-side power quality, taking into account photovoltaic governance resources based on insights from photovoltaic control realms and power quality classifications. Further, a collaborative allocation model for governance resources incorporating active optimization potentials of grid-connected converters is established based on the governance capabilities and residual capacities of PVMFGCI. Finally, the effectiveness of the proposed approach is validated through a MATLAB-based example analysis.
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  • 文章类型: Journal Article
    背景:在特发性脊柱侧凸中,前脊柱旋转远离中线,并通过椎间盘的卸载和扩张而变得更长。理论上,脊柱在矢状面的延伸应该为这个较长的前脊柱提供空间,允许它在冠状面和轴向面朝中线摆动,从而减少Cobb角和根尖椎体旋转。
    方法:在本前瞻性实验研究中,10例原发性胸部青少年特发性脊柱侧凸(AIS)患者在仰卧位以及在伸展位置通过放置一个宽的垫进行了MRI(BoneMRI和cVISTA序列),支持两个半边带,在脊柱侧凸顶点下。T4-T12后凸角度的差异,冠状Cobb角,椎骨旋转,以及椎间盘的形状和髓核的形状和位置,对这两个位置进行了分析和比较。
    结果:延长使T4-T12胸椎后凸减少10°(p<0.001),冠状Cobb角减小9°(p<0.001),椎体旋转4°(p=0.036)。椎间盘的冠状楔形显着正常化,楔形和偏侧的髓核部分减少到更对称的位置。
    结论:脊柱侧凸的简单延伸导致冠状和轴向平面的畸形减少。椎间盘的形状恢复正常,偏心髓核部分移回中线。
    BACKGROUND: In idiopathic scoliosis, the anterior spinal column has rotated away from the midline and has become longer through unloading and expansion of the intervertebral discs. Theoretically, extension of the spine in the sagittal plane should provide room for this longer anterior spinal column, allowing it to swing back towards the midline in the coronal and axial plane, thus reducing both the Cobb angle and the apical vertebral rotation.
    METHODS: In this prospective experimental study, ten patients with primary thoracic adolescent idiopathic scoliosis (AIS) underwent MRI (BoneMRI and cVISTA sequences) in supine as well as in an extended position by placing a broad bolster, supporting both hemi-thoraces, under the scoliotic apex. Differences in T4-T12 kyphosis angle, coronal Cobb angle, vertebral rotation, as well as shape of the intervertebral disc and shape and position of the nucleus pulposus, were analysed and compared between the two positions.
    RESULTS: Extension reduced T4-T12 thoracic kyphosis by 10° (p < 0.001), the coronal Cobb angle decreased by 9° (p < 0.001) and vertebral rotation by 4° (p = 0.036). The coronal wedge shape of the disc significantly normalized and the wedged and lateralized nucleus pulposus partially reduced to a more symmetrical position.
    CONCLUSIONS: Simple extension of the scoliotic spine leads to a reduction of the deformity in the coronal and axial plane. The shape of the disc normalizes and the eccentric nucleus pulposus partially moves back to the midline.
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  • 文章类型: Journal Article
    通过添加电子供体刺激本地微生物将水性U(VI)还原为不溶性U(IV)已被用作原位修复铀污染的地下水的适用策略。然而,生物U(IV)矿物质在暴露于氧气后容易氧化再动员。为了增强最终产品的稳定性,选择甘油磷酸盐(GP)来处理不同pH值的人造含铀地下水(即,7.0和5.0),以甘油(GY)为对照组。结果表明,GP对铀的去除率均高于GY,在GP组中产生了还原的结晶U(IV)-磷酸盐和U(VI)-磷酸盐矿物质(对氧化再固定有抑制作用)。尽管在pH5.0时生物还原效率受到影响,但与GY相比,GP的最终产物的稳定性显着提高。机理分析表明,GP可以激活微生物群落的生物还原和生物矿化,GP组包括两个阶段。在早期阶段,生物还原和生物矿化都参与了固定化过程。随后,部分U(VI)沉淀被微生物逐渐还原成U(IV)沉淀。这项工作表明,通过生物还原与生物矿化相结合形成U-磷酸盐矿物可能为长期稳定地修复受铀污染的地下水提供了更有效的策略。
    Stimulating indigenous microbes to reduce aqueous U(VI) to insoluble U(IV) by adding an electron donor has been applied as an applicable strategy to remediate uranium-contaminated groundwater in situ. However, biogenic U(IV) minerals are susceptible to oxidative remobilization after exposure to oxygen. To enhance the stability of the end product, glycerol phosphate (GP) was selected to treat artificial uranium-containing groundwater at different pH values (i.e., 7.0 and 5.0) with glycerol (GY) as the control group. The results revealed that removal ratios of uranium with GP were all higher than those with GY, and reduced crystalline U(IV)-phosphate and U(VI)-phosphate minerals (recalcitrant to oxidative remobilization) were generated in the GP groups. Although bioreduction efficiency was influenced at pH 5.0, the stability of the end product with GP was elevated significantly compared with that with GY. Mechanism analysis demonstrated that GP could activate bioreduction and biomineralization of the microbial community, and two stages were included in the GP groups. In the early stage, bioreduction and biomineralization were both involved in the immobilization process. Subsequently, part of the U(VI) precipitate was gradually reduced to U(IV) precipitate by microorganisms. This work implied that the formation of U-phosphate minerals via bioreduction coupled with biomineralization potentially offers a more effective strategy for remediating uranium-contaminated groundwater with long-term stability.
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  • 文章类型: Journal Article
    随着中国工会的改革,近年来,工会与工作场所的人力资源管理之间存在着明显的互动。然而,我们没有一个合适的概念来描述这种现象。因此,在回顾当前中国工会和人力资源管理相关文献的基础上,本研究旨在通过探索定义来描述工会实践与企业人力资源管理之间的互动关系,特点,和形成机制。本研究将工会与人力资源管理之间的关系定义为一种耦合关系,即工会与人力资源管理在企业中作为两个相对独立的系统不断地相互促进和约束。这种关系具有三个双重特征,即互惠与互惠克制,完整性与独立性,和稳定性与活力。工会和人力资源管理形成这种关系有三个顺序阶段,互动,共识,和调整。这项研究进一步深入了解了工会与工作场所人力资源管理之间的关系,并试图对这种关系进行全面的描述。该研究还为工会和企业建立高质量的合作关系提供了方向,这对企业的发展和员工的福祉是互惠互利的。
    With the reform of trade unions in China, there has been a noticeable interaction in recent years between trade unions and human resource management in the workplace. However, we do not have a proper concept to describe such a phenomenon. Therefore, based on reviewing the current literature involving trade unions and human resource management in China, this study aims to describe the interactive relation between union\'s practices and enterprises\' human resource management by exploring the definition, characteristics, and formation mechanism. This study defines the relationship between the trade unions and human resource management as a coupling relationship where the trade unions and human resource management continually promote and restrain each other as two relatively independent systems in the enterprise. This relationship possesses three dual characteristics, namely reciprocity vs. restraint, integrity vs. independence, and stability vs. dynamism. And there are three sequential stages for trade unions and human resource management to form such a relation, interaction, consensus, and adjustment. This study provides further insight into the relationship between trade unions and human resource management in the workplace and attempts a proximately complete description of the relationship. The study also offers a direction for trade unions and enterprises to establish high-quality cooperation with each other which is mutually beneficial for enterprises\' development and employees\' wellbeing.
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  • 文章类型: Journal Article
    具有异源T辅助表位(T辅助VLP)的实验性HIV-1病毒样颗粒疫苗的功能化可以通过结构内帮助(ISH)调节体液免疫应答。将天然样HIV-1包膜三聚体(Env)缀合到脂质体上以及将肽表位包封到这些纳米颗粒中的当前进展使得该GMP可扩展的脂质体平台成为基于VLP的疫苗的可行替代方案。在这项研究中,我们设计并分析了可定制的Env偶联T辅助脂质体。首先,我们被动地将T辅助肽包封到充分表征的脂质体制剂中,在表面上显示出密集的Env三聚体阵列。我们通过用构象特异性抗体的免疫金染色证实了偶联的Env三聚体的闭合融合前状态。这些负载肽的Env-脂质体缀合物有效地激活了Env特异性B细胞,其通过在MHC-II分子上呈递脂质体衍生的肽进一步诱导CD4+T细胞的增殖。然后通过使用整体阴离子脂质制剂的静电驱动方法定量地改进肽封装过程。我们证明了脂质体递送的肽在小鼠肌内免疫后由次级淋巴器官中的DC呈递。通过His-tag/NTA(Ni)相互作用和EDC/Sulfo-NHS交联,将UFO(未切割的预融合优化)Env三聚体共价偶联至负载肽的阴离子脂质体。EM成像显示脂质体表面上中等密集的折叠良好的Env三聚体阵列。通过脂质体表面FACS验证构象。此外,阴离子Env偶联的T辅助脂质体在与T辅助VLP相当的范围内有效地诱导Env特异性B细胞活化和增殖。一起来看,我们证明T辅助VLP可以被可定制和GMP可扩展的脂质体纳米颗粒替代,作为未来临床前和临床HIV疫苗应用的前景.本研究中显示的功能性纳米颗粒表征测定可应用于递送源自各种病原体的抗原的合成纳米颗粒的其他系统。
    Functionalization of experimental HIV-1 virus-like particle vaccines with heterologous T helper epitopes (T helper VLPs) can modulate the humoral immune response via intrastructural help (ISH). Current advances in the conjugation of native-like HIV-1 envelope trimers (Env) onto liposomes and encapsulation of peptide epitopes into these nanoparticles renders this GMP-scalable liposomal platform a feasible alternative to VLP-based vaccines. In this study, we designed and analyzed customizable Env-conjugated T helper liposomes. First, we passively encapsulated T helper peptides into a well-characterized liposome formulation displaying a dense array of Env trimers on the surface. We confirmed the closed pre-fusion state of the coupled Env trimers by immunogold staining with conformation-specific antibodies. These peptide-loaded Env-liposome conjugates efficiently activated Env-specific B cells, which further induced proliferation of CD4+ T cells by presentation of liposome-derived peptides on MHC-II molecules. The peptide encapsulation process was then quantitatively improved by an electrostatically driven approach using an overall anionic lipid formulation. We demonstrated that peptides delivered by liposomes were presented by DCs in secondary lymphoid organs after intramuscular immunization of mice. UFO (uncleaved prefusion optimized) Env trimers were covalently coupled to peptide-loaded anionic liposomes by His-tag/NTA(Ni) interactions and EDC/Sulfo-NHS crosslinking. EM imaging revealed a moderately dense array of well-folded Env trimers on the liposomal surface. The conformation was verified by liposomal surface FACS. Furthermore, anionic Env-coupled T helper liposomes effectively induced Env-specific B cell activation and proliferation in a comparable range to T helper VLPs. Taken together, we demonstrated that T helper VLPs can be substituted with customizable and GMP-scalable liposomal nanoparticles as a perspective for future preclinical and clinical HIV vaccine applications. The functional nanoparticle characterization assays shown in this study can be applied to other systems of synthetic nanoparticles delivering antigens derived from various pathogens.
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  • 文章类型: Journal Article
    挥发性有机物(VOCs)危害人类健康和生态环境。这项工作证明了氧化锰催化膜与催化膜生物膜反应器(CMBfR)中甲苯的生物降解耦合。在200天的操作中,CMBfR中的甲苯去除效率高达91%。氧化锰结合膜生物膜反应器可以促进甲苯的降解。通过XRD对氧化锰催化剂进行了表征,拉曼,XPS,和FT-IR。拉曼光谱和XPS光谱验证了Mn缺陷的存在,吸附的氧物种,和氧空位,甲苯对Mn氧化物涂层膜的催化作用显着。假单胞菌,Hydrogenophaga,黄杆菌,芽孢杆菌,降解甲苯的优势菌为梭状芽孢杆菌和原杆菌属。Mn氧化物催化可以将甲苯降解为中间产物;这些产物进入生物相,最终代谢为CO2和H2O。这些结果表明,催化膜生物膜反应器是可实现的,并为将催化膜生物膜反应器应用于VOC处理开辟了新的可能性。
    Volatile organic compounds (VOCs) harm human health and the ecological environment. This work demonstrated manganese oxide catalytic membrane coupled to biodegradation of toluene in a catalytic membrane biofilm rector (CMBfR). Toluene removal efficiency in CMBfR was up to 91% in a 200-day operation. Manganese oxide combined to membrane biofilm reactor could promote degradation of toluene. Manganese oxide catalysts were characterized by XRD, Raman, XPS, and FT-IR. Raman and XPS spectra verified the existence of Mn defects, adsorbed oxygen species, and the oxygen vacancy, which was catalytic of toluene on the Mn oxides coated membranes significantly. Pseudomonas, Hydrogenophaga, Flavobacterium, Bacillus, Clostridium and Prosthecobacter were the dominant bacteria of toluene degradation. Mn oxides catalysis could degrade toluene into intermediate products; these products were entered into the biological phase eventually metabolized to CO2 and H2O. These results show that the catalytic membrane biofilm reactor is achievable and opens new possibilities for applying the catalytic membrane biofilm reactor to VOCs treatment.
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  • 文章类型: Journal Article
    The small white cabbage butterfly (Pieris rapae) flaps its fore- and hindwings in synchrony as the wings are coupled using a wing \"coupling mechanism\". The coupling mechanism of butterflies includes an enlarged humeral area located at the anterior of the hindwing base and a corresponding basal posterior part of the forewing, of which the former component dorsally contacts the ventral side of the latter one. The coupling mechanism allows for the fore- and hindwings sliding in contact along the span and chord. It is of interest that butterflies still take off successfully and fly, when their wing couplings are clipped, but they are unable to properly synchronize the fore- and hindwing motions. Compared with the regular takeoff trajectory of intact butterflies that always first fly backwards and then forwards, the coupling-clipped butterflies took off in a random trajectory. Due to the clipping of the coupling mechanism, the initiation of the hindwing flapping and the abdomen rotation from upward to downward during takeoff was postponed. The coupling-clipped butterflies changed their stroke plane in upstroke to a more vertical position and strengthened the abdominal undulation. We believe our work, which for the first time investigates the influence of coupling mechanism removal on insect flight, extends our understanding on the working principle of wing coupling in insects and its significance on the flapping flight.
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  • 文章类型: Journal Article
    It would be highly beneficial to use the methane produced by anaerobic digestion, which is low cost and accessible, as the carbon source in the removal of nitrogenous contaminants in wastewater. However, there is a knowledge gap regarding coupling systems that entail methane oxidation, nitrification, and denitrification, which restricts their industrial application. In this study, we acclimated a mixed culture to deal with simultaneous nitrification-denitrification coupled to methane oxidation in a laboratory-scale hollow-fiber membrane biofilm reactor, which achieved a steady ammonia removal rate of 38.09 mg N/(L•d). Furthermore, a series of batch experiments were conducted to test methane oxidation coupled to nitrate denitrification (AME-D3), nitrite denitrification (AME-D2), and simultaneous nitrification and denitrification (ME-SND). The molar ratio between methane consumed and nitrate reduced (C/N) equals 10 and 5 mol CH4C mol-1 NO3N in AME-D3 and AME-D2, averagely and respectively. Without methane injection, the removal of nitrates and nitrites was very low, indicating that the coupling of nitrate/nitrite denitrification and methane oxidation was beneficial. The average ammonia removal rates in the 20% O2 and 25% O2 groups were 20.06 and 22.03 mg N/(L•d) in the ME-SND system, respectively. Without methane, the ammonia oxidation rate declined, and large amounts of nitrite accumulated. As traditional ammonia and nitrite oxidation approaches are autotrophic, we proposed the possibility of heterotrophic nitrification-aerobic denitrification (HN-AD). To study the coupling systems, the microbial communities and functional bacteria were analyzed. The results indicated that the system contained a guild of methanotrophs (mainly Methylobacter) and HN-AD bacteria (mainly Chrysobacterium and Comamonas).
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  • 文章类型: Journal Article
    Composite prepreg tape winding technology has proven to be an effective method for manufacturing revolving body composite structures in aerospace field. Process parameters including heating temperature, tape tension and roller pressure have an important impact on the winding products\' mechanical property such as tensile strength. The aim of this study is to investigate the influence mechanism and optimization analysis of parameters for the composite prepreg tape winding process. Firstly, the sensitivity analysis for single parameter had be employed to reveal the influence mechanism of each winding parameter change on tensile strength. Secondly, iso-surfaces analysis for parameter range had be applied to describe the distribution law of parameter with continuous distribution characteristics. Then the coupling analysis for process parameters was carried out employing response surface methodology. The analysis results showed that tape tension has the most significant effect on the winding products\' tensile strength. And the outstanding parameter combination with the heating temperature of 72 °C, tape tension of 307 N and roller pressure of 1263 N was provided by response surface design software via desirability function method. The validation experiments showed that the optimal parameter combination has a positive guiding significance for improving the quality of winding products.
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