■脑血管疾病通常定义为短暂性脑缺血发作和中风。然而,它们也可能导致脑损伤而没有神经系统事件。沉默性脑梗塞(SBI)和脑白质疏松是血管和神经系统异常的症状。这项研究旨在调查SBI,脑白质疏松症,和中年缺血性卒中患者。
■一项针对50名中年人的单中心回顾性研究,从2022年11月和2023年5月对缺血性卒中患者进行了研究.根据是否存在脑白质疏松症,将患者分为两组。历史,体检,脑部CT扫描,和MRI都是诊断过程的一部分。还通过各种因素评估了代谢综合征(MetS)。统计分析包括描述性统计,Logistic回归分析,和卡方检验。
■在包含50名患者的队列中,以平均年龄52.26岁(SD5.29)为特征,32是男性,占样本的64%。在这些患者中,26人表现出脑白质疏松症,其中17人(65.4%)也出席了SBI会议。此外,在这个群体中,22例患者被诊断为MetS,占受影响者的84.6%。多因素logistic回归分析显示,脑白质疏松与SBI之间存在强烈且独立的关联。与没有脑白质疏松的人相比,患有脑白质疏松的人患SBI的可能性几乎是后者的五倍。
■该研究强调脑白质疏松是SBI的重要危险因素,在MetS旁边。先进的成像技术促进了它们的检测,显示中风患者的患病率较高,特别是与年龄和高血压有关。需要进一步的研究,以充分了解它们之间的复杂关系,并制定更好的脑血管疾病管理策略,最终改善患者预后。
UNASSIGNED: Cerebrovascular diseases of the brain are usually defined by transient ischemic attacks and strokes. However, they can also cause brain injuries without neurological events. Silent brain infarcts (SBI) and leukoaraiosis are symptoms of both vascular and neurological abnormalities. This study aims to investigate the association between SBI, leukoaraiosis, and middle-aged patients with ischemic stroke.
UNASSIGNED: A single-center retrospective study of 50 middle-aged, ischemic stroke patients were studied from November 2022 and May 2023. The patients were divided into two groups based on the presence or absence of leukoaraiosis. History taking, physical examination, brain CT scan, and MRI were all part of the diagnostic process. Metabolic syndrome (MetS) was also assessed through various factors. The statistical analysis included descriptive statistics, logistic regression analysis, and chi-square test.
UNASSIGNED: Out of the cohort comprising 50 patients, characterized by a mean age of 52.26 years (SD 5.29), 32 were male, constituting 64% of the sample. Among these patients, 26 individuals exhibited leukoaraiosis, with 17 of them (65.4%) also presenting with SBI. Moreover, within this cohort, 22 patients were diagnosed with MetS, representing 84.6% of those affected. The Multivariate logistic regression analysis showed a strong and independent association between leukoaraiosis and SBI. Individuals with leukoaraiosis were nearly five times more likely to have SBI compared to those without leukoaraiosis.
UNASSIGNED: The study highlights leukoaraiosis as a significant risk factor for SBI, alongside MetS. Advanced imaging techniques have facilitated their detection, revealing a higher prevalence among stroke patients, particularly associated with age and hypertension. Further research is needed to fully understand their complex relationship and develop better management strategies for cerebrovascular diseases, ultimately improving patient outcomes.