目的:本研究旨在控制所有听阈,包括扩展高频(EHF),呈现不同难度水平的刺激,并测量脑电图(EEG)和瞳孔测量反应,以确定耳鸣患者的听力困难是否与努力或疲劳有关。
方法:包括21名慢性耳鸣患者和26名具有正常纯音平均值和对称听阈的匹配健康对照。受试者用0.125-20kHz纯音测听法进行评估,蒙特利尔认知评估测试(MoCA)耳鸣障碍清单(THI),脑电图,和瞳孔测量。
结果:在所有听音条件下,耳鸣患者在“编码”阶段的瞳孔扩张和脑电图α功率较少(p<0.05)。此外,对于所有听力条件和THI或MoCA,EEG和瞳孔测量分量之间没有统计学上的显着关系(p>.05)。
结论:各种听力条件下的EEG和瞳孔测量结果表明耳鸣患者即使所有频率,也有潜在的听力努力。包括EHFs,被控制。此外,我们建议在与自主神经系统相关的疾病如耳鸣时,应谨慎进行瞳孔测量。
OBJECTIVE: This study aims to control all hearing thresholds, including extended high frequencies (EHFs), presents stimuli of varying difficulty levels, and measures electroencephalography (EEG) and pupillometry responses to determine whether listening difficulty in tinnitus patients is effort or fatigue-related.
METHODS: Twenty-one chronic tinnitus patients and 26 matched healthy controls having normal pure-tone averages with symmetrical hearing thresholds were included. Subjects were evaluated with 0.125-20 kHz pure-tone audiometry, Montreal Cognitive Assessment Test (MoCA), Tinnitus Handicap Inventory (THI), EEG, and pupillometry.
RESULTS: Pupil dilatation and EEG alpha power during the \"encoding\" phase of the presented sentence in tinnitus patients were less in all listening conditions (p < .05). Also, there was no statistically significant relationship between EEG and pupillometry components for all listening conditions and THI or MoCA (p > .05).
CONCLUSIONS: EEG and pupillometry results under various listening conditions indicate potential listening effort in tinnitus patients even if all frequencies, including EHFs, are controlled. Also, we suggest that pupillometry should be interpreted with caution in autonomic nervous system-related conditions such as tinnitus.