Aortoiliac occlusive disease

主动脉闭塞性疾病
  • 文章类型: Journal Article
    根据在Songklanagarind医院的10年经验,研究血管内治疗主动脉闭塞性疾病(AIOD)的技术考虑因素。
    这项回顾性队列研究纳入了2010年1月至2020年12月期间接受有症状AIOD血管内治疗的210例患者。患者的临床和病变特征,包括程序的技术考虑,被收集,分析,并使用跨大西洋社会间共识(TASC)进行分层。
    这项研究中的大多数患者(80%)患有慢性威胁肢体的缺血病变,闭塞率为37%。TASCC&D的技术成功率低于TASCA&B,84.4%vs.99.2%p≤0.001。股骨和肱入路的技术成功率为93.3%(14/15),与TASCC&D中单声入路的89.0%(57/64)的成功率相比,无统计学差异(p=0.076)。然而,该途径的穿刺部位并发症高达17.6%,与其他技术相比,这是最高的比率。这些并发症可以保守或微创治疗。
    在股骨入路失败的情况下,股动脉和肱动脉同时入路提高了TASCC&D主髂动脉闭塞血管内再通的技术成功率。
    UNASSIGNED: To examine the technical considerations of endovascular treatment for aortoiliac occlusive disease (AIOD) based on a 10-year experience in Songklanagarind Hospital.
    UNASSIGNED: This retrospective cohort study included 210 patients who underwent endovascular treatment for symptomatic AIOD between January 2010 and December 2020. The patients\' clinical and lesion characteristics, including technical considerations of the procedure, were collected, analyzed, and stratified using the Transatlantic Inter-Society Consensus (TASC).
    UNASSIGNED: Most patients (80%) in this study had chronic limb-threatening ischemia lesions, with an occlusion rate of 37%. The technical success rate of TASC C & D was lower than that of TASC A & B, 84.4% vs. 99.2% p ≤ 0.001. A technical success rate of 93.3% (14/15) was found for the femoral and brachial approach, compared with a success rate of 89.0% (57/64) for the unibifemoral approach in TASC C & D, without a statistically significant difference (p = 0.076). However, the puncture site complications in this route were up to 17.6%, which is the highest rate compared with other techniques. These complications could be treated either conservatively or minimally invasively.
    UNASSIGNED: In cases of failed femoral access, simultaneous femoral and brachial approaches improved the technical success rate of endovascular recanalization of TASC C & D aortoiliac occlusions.
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  • 文章类型: Journal Article
    背景:本研究探讨了Begraft和Solaris支架移植物的组合使用对主动脉分叉覆膜血管内重建(BS-CERAB)技术和延伸至the动脉的结果的影响。方法:纳入2020年1月至2023年12月间接受BS-CERAB血管内治疗的主动脉髂动脉闭塞性疾病患者。患者人口统计学,症状,病变特征,收集并分析了程序和随访细节.还确定了围手术期并发症和再干预措施。结果:共有42例患者符合纳入标准(32例男性,76.2%,中位年龄72岁,范围59-85)。治疗指征为间歇性跛行(42.9%)和严重肢体缺血(57.1%)。在所有情况下都取得了成功。患者中位随访时间为14个月(1~36个月)。一名患者因肺癌在10个月的随访中死亡。术前平均ABI从干预前的0.37±0.19增加到术后12个月的0.71±1.23(p=0.037)。估计3、6和12个月的主要通畅率为90.5%,85.7%,81.0%,初级辅助通畅率为90.5%,90.5%,和85.7%,分别。随访3个月和6个月时,继发性通畅率为95.2%,12个月时为90.5%。活动性癌症(p=0.023,OR2.1295CI1.14-3.25)是再狭窄的危险因素。结论:中期经验表明,CERAB技术使用Begraft和Solaris支架移植的组合,用于严重主动脉粥样硬化疾病的血管内治疗,可以有效重建与高通畅性和低再介入率相关的主动脉分叉和髂动脉。
    Background: This study examines the impact of the use of the combination of BeGraft and Solaris stent grafts on the outcomes during the covered endovascular reconstruction of aortic bifurcation (BS-CERAB) technique and extension to the iliac arteries. Methods: Consecutive patients with aortoiliac occlusive disease who underwent endovascular treatment using BS-CERAB between January 2020 and December 2023 were included. Patient demographics, symptoms, lesion characteristics, and procedural and follow-up details were collected and analyzed. Perioperative complications and reinterventions were also identified. Results: A total of 42 patients met the inclusion criteria (32 men, 76.2%, median age 72 years, range 59-85). Indications for treatment were intermittent claudication (42.9%) and critical limb ischemia (57.1%). Procedure success was achieved in all cases. The median patient follow-up time was 14 months (1-36). One patient died at a 10-month follow-up due to lung cancer. The mean pre-operative ABI increased from 0.37 ± 0.19 before intervention to 0.71 ± 1.23 post-operatively at 12 months (p = 0.037). The estimated primary patency rates at 3, 6, and 12 months were 90.5%, 85.7%, and 81.0% and primary assisted patency rates were 90.5%, 90.5%, and 85.7%, respectively. Secondary patency was 95.2% at 3 and 6 months and 90.5% at a 12-month follow-up. Active cancer (p = 0.023, OR 2.12 95%CI 1.14-3.25) was a risk factor for restenosis. Conclusions: This mid-term experience shows that the CERAB technique using the combination of BeGraft and Solaris stents grafts, for the endovascular treatment of severe aortoiliac atherosclerotic disease, may allow an effective reconstruction of the aortic bifurcation and iliac arteries related to high-patency and lower-reintervention rates.
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  • 文章类型: Case Reports
    手术不良患者的主动脉闭塞性疾病需要血管内手术的创新策略。我们介绍了一例59岁的绅士,患有严重的医学合并症和慢性威胁肢体的缺血,继发于慢性闭塞的左右股动脉旁路手术,以及右髂系统闭塞,原因是右髂外动脉从先前的髂内覆盖支架被监禁,最初是为臀部跛行做的。在通过同侧通路进入旧的右髂总支架并使用Pioneer血管内超声引导的再入室导管后,通过右髂内动脉和外动脉的亲吻支架成功治疗了他。使用这种策略来治疗不适合手术的患者的复杂主髂动脉闭塞可以有效地实现,即使在现有的同侧支架移植物的设置。
    Aortoiliac occlusive disease in patients who are poor surgical candidates requires innovative strategies in endovascular surgery. We present a case of a 59-year-old gentleman with significant medical comorbidities and chronic limb-threatening ischemia secondary to a chronically occluded left-to-right cross-femoral bypass, as well as an occluded right iliac system owing to a jailed right external iliac artery from a prior common-to-internal iliac covered stent, originally done for buttock claudication. He was treated successfully from an endovascular approach with kissing stents in the right internal and external iliac arteries after gaining access to the old right common iliac stent via an ipsilateral access and use of a Pioneer intravascular ultrasound-guided re-entry catheter. Use of this strategy to treat complex aortoiliac occlusions in patients that are not suitable surgical candidates can be achieved effectively, even in the setting of existing prior ipsilateral stent grafts.
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  • 文章类型: Journal Article
    本研究旨在报告接受血管内介入治疗的患者的中期结果,亲吻支架,或覆盖主动脉分叉的血管内重建,涉及主动脉分叉的跨大西洋社会共识C或D主动脉闭塞性疾病。
    2018年1月至2021年1月期间,18名患有间歇性跛行或慢性威胁肢体缺血的跨大西洋学会共识C或D型主动脉髂动脉闭塞性疾病的患者纳入研究。亲吻支架,AdvantaV12(中庭,GetingeGroup),用于13名患者,4例患者采用覆膜血管内重建主动脉分叉技术进行主动脉分叉重建。对患者进行了中位49个月的随访(分钟。2,最大58个月)。通畅率,死亡率,发病率,并记录了再干预措施。
    患者的平均年龄为60.4±10岁。94.4%的患者获得了技术上的成功,但一名患者不得不转为开放手术.其余患者在58个月时的主要通畅率为85.6%。靶病变血运重建率为11.7%。一名患者成功再介入支架再狭窄,58个月时二次通畅率为93.3%。随访期间肢体抢救率为84.6%。2例患者发生心肌梗死(11.1%),1例因脑血管事件而死亡(5.6%)。
    血管内技术可安全地用于跨大西洋社会共识C或D型主动脉闭塞性疾病的主动脉分叉重建,这些患者具有高风险的开放性手术。主动脉分叉的覆盖血管内重建是迄今为止在治疗涉及主动脉分叉的主动脉闭塞性疾病中唯一显示接近开放手术的通畅率的技术。尽管接吻覆盖的支架获得了有希望的通畅效果,长期通畅率仍低于开放手术.需要进一步的随机对照研究来比较这些技术的长期结果。
    UNASSIGNED: The current study aims to report midterm results of patients treated with endovascular intervention, kissing stent, or covered endovascular reconstruction of the aortic bifurcation, for Trans-Atlantic Inter-Society Consensus C or D aortoiliac occlusive disease involving the aortic bifurcation.
    UNASSIGNED: Eighteen patients who have intermittent claudication or chronic limb threatening ischemia with Trans-Atlantic Inter-Society Consensus C or D aortoiliac occlusive disease involving the aortic bifurcation enrolled to the study between January 2018 and January 2021. Kissing stents, Advanta V12 (Atrium, Getinge Group), were used in 13 patients, and the covered endovascular reconstruction of the aortic bifurcation technique was used in 4 patients to reconstruct the aortic bifurcation. The patients were followed for a median of 49 months (min. 2, max.58 months). Patency rates, mortality, morbidities, and reinterventions were recorded.
    UNASSIGNED: The mean age of the patients was 60.4 ± 10 years. Technical success was achieved in 94.4% of the patients, but one patient had to convert to open surgery. Primary patency rate of the remaining patients was 85.6% at 58 months. Target lesion revascularization rate was 11.7%. One patient had successful reintervention for in stent restenosis, and secondary patency rate was 93.3% at 58 months. Limb salvage rate was 84.6% during the follow-up. Two patients had myocardial infarction (11.1%) and one mortality (5.6%) occurred because of cerebrovascular event in the follow-up.
    UNASSIGNED: Endovascular techniques can be used safely for reconstruction of the aortic bifurcation in Trans-Atlantic Inter-Society Consensus C or D aortoiliac occlusive disease in selected patients who have high risk for open surgery. Covered endovascular reconstruction of the aortic bifurcation is the only technique that showed patency rates approaching open surgery in treatment of aortoiliac occlusive disease involving the aortic bifurcation to date. Although promising patency results were achieved with kissing-covered stents, long-term patency rates were still lower than those achieved with open surgery. Further randomized controlled studies comparing the long-term results of these techniques are needed.
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  • 文章类型: Journal Article
    外周动脉疾病(PAD)影响全球超过2亿,是主要截肢的主要原因,与对照组相比,患有PAD的个体的死亡风险是对照组的三倍。TASC-II指南基于国际血管专科之间的合作,就PAD的管理达成了共识。这些指南先前概述了开放手术作为治疗主髂动脉疾病和PAD的金标准,因为它已经证明了一致的长期结果。然而,这种方法也与高的围手术期死亡率有关,特别是与血管内技术相比。随着血管内技术的发展,用户技术,和经验,这种方法已被更广泛地用作主髂动脉疾病的主要干预措施.这些新技术之一包括主动脉分叉的覆盖血管内重建,这证明了出色的技术成功,并提高了随访的主要和次要通畅率。这篇综述的目的是比较这些方法治疗主髂动脉疾病的疗效,并证明转向血管内优先治疗该疾病的好处。无论病变的复杂性或严重程度。
    Peripheral arterial disease (PAD) affects over 200 million worldwide and is the leading cause of major limb amputation, with individuals suffering from PAD being at three times greater risk of dying compared with matched controls. TASC-II guidelines provide a consensus on the management of PAD based on the collaboration between international vascular specialties. These guidelines previously outlined open surgery as the gold standard for treatment of aortoiliac disease and PAD as it has demonstrated consistent long-term results. However, this approach is also associated with high perioperative mortality, especially when compared with endovascular techniques. With recent developments in endovascular technology, user technique, and experience, this approach has become more widely used as primary intervention for aortoiliac disease. One of these novel techniques includes covered endovascular reconstruction of the aortic bifurcation, which has demonstrated excellent technical success and improved primary and secondary patency rates with follow-up. The aim of this review is to compare the efficacy of these approaches to the treatment of aortoiliac disease and demonstrate the benefits of the shift toward an endovascular-first approach to treatment of this disease, regardless of lesion complexity or severity.
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  • 文章类型: Journal Article
    研究并比较血管内治疗与杂交手术治疗跨大西洋学会共识II(TASCII)D主动脉闭塞性疾病(AIOD)的临床结果。
    在2018年3月至2021年3月期间在我们医院接受首次手术治疗的TASCIID型AIOD患者被招募并随访以评估症状的改善。并发症,和初级通畅。使用Kaplan-Meier方法比较治疗组之间原发性通畅性的差异。
    总共,139名入选患者中有132名(94.96%)在治疗后取得了技术成功。围手术期死亡率为1.44%(2/139),2例患者发生术后并发症。在成功接受手术的患者中,120例接受了血管内治疗(110例支架置入,10例支架置入前溶栓),10人接受了混合手术,2人接受了开放手术。比较血管内和杂交组的随访数据。在随访期结束时,混合组和腔内通畅率分别为100%和89.17%(107/120),分别。血管内组的原发通畅率为94.12%,92.44%,术后6、12和24个月为89.08%,分别,而混合组的主要通畅率保持在100%,血管内和混合组之间没有显着差异(P=0.289)。血管内组又分为支架亚组(110例)和溶栓/支架亚组(10例),两个亚组之间的主要通畅性没有显著差异(P=0.276).
    尽管开放手术是TASCIID型AIOD的黄金标准治疗方法,血管内和混合治疗是可行和有效的。两种方法均显示出良好的技术成功和早期至中期的原发性通畅率。
    UNASSIGNED: To study and compare the clinical outcomes of endovascular therapy with those of hybrid surgery in the treatment of Trans-Atlantic Inter-Society Consensus II (TASC II) D aortoiliac occlusive disease (AIOD).
    UNASSIGNED: Patients with TASC II D-type AIOD who underwent their first surgical treatment at our hospital between March 2018 and March 2021 were enrolled and followed up to evaluate the improvement in symptoms, complications, and primary patency. The Kaplan-Meier method was used to compare the differences in primary patency between the treatment groups.
    UNASSIGNED: In total, 132 of 139 enrolled patients (94.96%) achieved technical success following treatment. The perioperative mortality rate was 1.44% (2/139), and postoperative complications occurred in two patients. Among the patients who successfully underwent surgery, 120 underwent endovascular treatment (110 patients with stenting and 10 patients with thrombolysis before stenting), 10 underwent hybrid surgery, and 2 underwent open surgery. The follow-up data were compared between the endovascular and hybrid groups. At the end of the follow-up period, the patency rates in the hybrid and endovascular groups were 100% and 89.17% (107/120), respectively. The endovascular group achieved primary patency rates of 94.12%, 92.44%, and 89.08% at 6, 12, and 24 months postoperatively, respectively, whereas the primary patency rate remained at 100% in the hybrid group, with no significant variation between the endovascular and hybrid groups (P = 0.289). The endovascular group was further divided into a stent subgroup (110 patients) and a thrombolysis/stent subgroup (10 patients), and no prominent variation was noted in the primary patency between the two subgroups (P = 0.276).
    UNASSIGNED: Although open surgery is the gold standard treatment for TASC II D-type AIOD, endovascular and hybrid treatments are feasible and effective. Both methods showed good technical success and early to midterm primary patency rates.
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  • 文章类型: Case Reports
    涉及肠系膜分支的主动脉闭塞性疾病提出了一个有趣的挑战。虽然开放手术方法被认为是黄金标准,血管内技术,例如用肠系膜下动脉烟囱覆盖的主动脉分叉腔内重建,已被用作不适合进行大型手术修复的患者的替代方法。一名64岁的患有双侧慢性威胁肢体缺血和严重慢性营养不良的男子,由于术中存在重大风险,因此接受了带有肠系膜下动脉烟囱的主动脉分叉的血管内重建。我们已经介绍了所使用的手术技术。术中成功,and,术后,病人经历了成功,计划,左膝下截肢,右下肢伤口愈合。
    Aortoiliac occlusive disease involving mesenteric branches poses an interesting challenge. Although an open surgical approach is considered the gold standard, endovascular techniques such as covered endovascular reconstruction of the aortic bifurcation with inferior mesenteric artery chimney have been presented as alternatives for patients unfit for major surgical repair. A 64-year-old man with bilateral chronic limb-threatening ischemia and severe chronic malnutrition underwent covered endovascular reconstruction of the aortic bifurcation with inferior mesenteric artery chimney due to significant intraoperative risk. We have presented the operative technique used. The intraoperative course was successful, and, postoperatively, the patient underwent successful, planned, left below-the-knee amputation and his right lower extremity wounds healed.
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  • 文章类型: Journal Article
    主动脉闭塞性疾病(AIOD)的最佳管理策略仍有争议。这项研究比较了直接手术旁路术和接吻支架治疗AIOD的早期和晚期结果。
    我们回顾性审查了数据,包括年龄,性别,危险因素,合并症,症状,跨大西洋社会共识(TASC)II分类,操作时间,围手术期并发症,住院死亡率,以及住院时间,从2007年1月至2016年12月在釜山国立大学Hostpital接受AIOD治疗的46例患者(24例接受亲吻支架治疗,22例接受直接手术搭桥治疗)的队列中得出。主要的,辅助小学,比较两组的二次通畅率。
    住院时间(直接手术搭桥与亲吻支架:16.36±5.19天vs.9.08±10.88天,p=0.007)和手术时间(直接手术旁路与亲吻支架:316.09±141.78分钟vs.99.54±37.95分钟,p<0.001)对于亲吻支架明显较短。Kaplan-Meier分析显示,辅助小学,直接手术搭桥组的二次通畅率为95.5%,95.5%,和95.5%,分别,1年;86.4%,86.4%,三年为95.5%;和77.3%,77.3%,5年为95.5%。主要的,辅助小学,接吻支架组的二次通畅率为100.0%,100.0%,和100.0%,分别,一年;95.8%,95.8%,3年为100.0%;95.8%,95.8%,5年为100.0%。
    除了血管内血运重建困难的特殊情况,亲吻支架对TASCIIC和D病变更有利。
    UNASSIGNED: The optimal management strategy for aortoiliac occlusive disease (AIOD) remains debatable. This study compared early and late outcomes between direct surgical bypass and kissing stents for AIOD treatment.
    UNASSIGNED: We retrospectively reviewed data, including age, sex, risk factors, comorbidities, symptoms, TransAtlantic Inter-Society Consensus (TASC) II classification, operation time, perioperative complications, in-hospital mortality, and length of hospital stay, from a cohort of 46 patients treated for AIOD (24 with kissing stents and 22 with direct surgical bypass) at Pusan National University Hostpital from January 2007 to December 2016. The primary, assisted primary, and secondary patency rates in both groups were compared.
    UNASSIGNED: The hospital stay (direct surgical bypass vs. kissing stents: 16.36±5.19 days vs. 9.08±10.88 days, p=0.007) and operation time (direct surgical bypass vs. kissing stents: 316.09±141.78 minutes vs. 99.54±37.95 minutes, p<0.001) were significantly shorter for kissing stents. Kaplan-Meier analysis revealed that the primary, assisted primary, and secondary patency rates in the direct surgical bypass group were 95.5%, 95.5%, and 95.5%, respectively, at 1 year; 86.4%, 86.4%, and 95.5% at 3 years; and 77.3%, 77.3%, and 95.5% at 5 years. The primary, assisted primary, and secondary patency rates in the kissing stent group were 100.0%, 100.0%, and 100.0%, respectively, at 1 year; 95.8%, 95.8%, and 100.0% at 3 years; and 95.8%, 95.8%, and 100.0% at 5 years.
    UNASSIGNED: Except for special cases wherein endovascular revascularization is difficult, kissing stents are more advantageous for TASC II C and D lesions.
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  • 文章类型: Journal Article
    在主动脉闭塞性疾病中,动脉粥样硬化斑块可阻塞远端主动脉分叉和近端双侧髂动脉,从而引起下肢缺血。这通常通过用球囊可扩张支架恢复开放来治疗。支架通常以“亲吻支架”构型部署到双侧髂动脉和远端主动脉分叉腔中,以恢复顺行动脉血流。然而,这些支架通常会被斑块重新闭塞。要了解原因并寻找解决方案,我们使用计算流体动力学模拟了存在和不存在支架的主动脉分叉处的流动动力学。结果表明,亲吻支架配置与高水平的涡旋和流量收缩有关。这些血栓前变量在替代方案中得到缓解,主动脉有窗(AIFEN),锥形,和球囊扩张支架设计。我们的发现表明,可以定制支架设计以改善主动脉支架置入的流场。
    In aortoiliac occlusive disease, atherosclerotic plaques can occlude the distal aortic bifurcation and proximal bilateral iliac artery and thus cause ischemia in the lower extremity. This is typically treated by restoring patency with balloon expandable stents. Stents are typically deployed in a \"kissing stent\" configuration into the bilateral iliac arteries and into the distal aortic bifurcation lumen to restore antegrade arterial flow. However, these stents typically become re-occluded by plaques. To understand the reasons for this and look for solutions, we simulated flow dynamics in the aortic bifurcation in the presence and absence of stents using computational fluid dynamics. Results demonstrated that the kissing stent configuration was associated with high levels of vorticity and flow constriction. These prothrombotic variables were alleviated in an alternative, aortoiliac fenestrated (AIFEN), tapered, and balloon-expandable stent design. Our findings suggest that stent design can be tailored to improve flow fields for aortoiliac stenting.
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  • 文章类型: Case Reports
    我们介绍了一名66岁的女性,患有严重的主动脉闭塞性疾病(TASC-D),并偶然发现了左侧下腔静脉,在术前计算机断层扫描中发现的。这种罕见的先天性发现可能给血管外科医生带来术中挑战。在这个案例报告中,我们已经描述了这种解剖变体,并详细阐述了我们的手术技术,为解决这些病例提供了一些提示和技巧。
    We present the case of a 66-year-old woman with severe aortoiliac occlusive disease (TASC-D) and an incidental finding of a left sided inferior vena cava, discovered on the preoperative computed tomography scan. This uncommon congenital finding can create intraoperative challenges to the vascular surgeon. In this case report, we have described this anatomic variant and elaborated on our surgical technique to suggest a few tips and tricks for addressing these cases.
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