目的:虚弱是一种普遍的老年病,对老年人的健康有显著影响。本研究旨在调查65岁以上中国老年人的身体虚弱患病率,并评估其与老年不良结局的相关性。
方法:本研究纳入江苏省20,724名年龄≥65岁的老年人,中国,利用随机的,分层,多级整群抽样方法。使用5项FRAIL量表评估虚弱。老年病结果,如日常生活活动的独立性(ADL),认知障碍,和频繁的跌倒事件(前一年发生四次或更多次),进行了评估。采用Logistic回归模型评估虚弱与老年结局之间的关联,结果以比值比(OR)和95%置信区间(CI)表示。
结果:参与者的平均年龄为73.4±6.4岁。脆弱和脆弱的标准化患病率分别为35.2%和10.3%,分别。被认定为脆弱或脆弱的人往往生活在农村地区,教育水平较低,丧偶,收入较低,从事较少的体力活动。优先和虚弱与BADL(OR:9.62,95%CI:7.43-12.46;OR:29.25,95%CI:22.42-38.17)和IADL(OR:2.54,95%CI2.35-2.74;和OR:5.19,95%CI4.66-5.78)的局限性风险增加有关,认知障碍筛查阳性(OR:1.23,95%CI:1.16-1.31;和OR:1.72,95%CI:1.56-1.91),和频繁跌倒(上一年发生四次或更多次)(OR:3.38,95%CI:2.50-4.56;OR:8.37,95%CI:6.01-11.65)。在年轻年龄组中,虚弱与BADL和跌倒的局限性之间的关联更为明显(相互作用p<0.001)。
结论:根据5项FRAIL量表,虚弱与BADLs和IADLs的局限性有关,认知障碍筛查阳性,以及最近居住在社区中的老年人的跌倒。筛查年轻年龄组的虚弱有可能防止身体功能下降和跌倒。
OBJECTIVE: Frailty is a prevalent geriatric condition that significantly impacts the health of older adults. This study aimed to examine the prevalence of frailty among older Chinese adults aged ≥ 65 years and to assess its association with adverse geriatric outcomes.
METHODS: This study included 20,724 older adults aged ≥ 65 years in Jiangsu Province, China, utilizing a random, stratified, multistage cluster sampling approach. Frailty was assessed using the 5-item FRAIL scale. Geriatric outcomes, such as independence in activities of daily living (ADL), cognitive impairment, and frequent fall events (occurring four or more times in the preceding year), were evaluated. Logistic regression models were employed to evaluate the association between frailty and geriatric outcomes, with results presented as odds ratios (ORs) and 95% confidence intervals (CIs).
RESULTS: The mean age of the participants was 73.4 ± 6.4 years. The standardized prevalence of prefrailty and frailty was 35.2% and 10.3%, respectively. Individuals identified as prefrail or frail tended to live in rural areas, have lower educational levels, be widowed, have lower incomes, and engage in less physical activity. Prefrailty and frailty were associated with an increased risk of limitations in BADL (OR: 9.62, 95% CI: 7.43-12.46; and OR: 29.25, 95% CI: 22.42-38.17, respectively) and IADL (OR: 2.54, 95% CI 2.35-2.74; and OR: 5.19, 95% CI 4.66-5.78, respectively), positive cognitive impairment screening (OR: 1.23, 95% CI: 1.16-1.31; and OR: 1.72, 95% CI: 1.56-1.91, respectively), and frequent falls (occurring four or more times in the preceding year) (OR: 3.38, 95% CI: 2.50-4.56; and OR: 8.37, 95% CI: 6.01-11.65). The association between frailty and both limitations in BADL and falls was notably more pronounced among the younger age groups (p for interaction < 0.001).
CONCLUSIONS: According to the 5-item FRAIL scale, frailty was associated with limitations in BADLs and IADLs, positive cognitive impairment screening, and recent falls among older adults living in the community. Screening for frailty in younger age groups has the potential to prevent declines in physical function and falls.