妊娠前庭神经鞘瘤很少有报道,对妊娠期大量听神经瘤的处理经验缺乏深入的探讨。在这里,我们介绍一名孕妇,在妊娠30周时出现巨大的前庭神经鞘瘤和梗阻性脑积水。她最初被误诊为怀孕相关的头痛反应,头晕,和2个月前发生的呕吐。在家观察后,她的症状在妊娠30周时进展,影像学检查结果显示,CPA区域的脑肿瘤伴有继发性小脑扁桃体疝和梗阻性脑积水,她被转到我们中心接受治疗.因此,我们用脑室-腹腔分流术(V-P分流术)缓解了她的脑积水,并使用皮质类固醇来模拟胎儿成熟。10天后,她的精神状况恶化了,右肢体肌力逐渐下降至0级(MMT分级)。最后,在与神经外科的联合协商下,产科,和麻醉学,她在妊娠31周时在全身麻醉下接受了剖宫产术,并进行了一期肿瘤切除.出院时,之前观察到的神经功能缺损,这是可逆的,在她的妊娠期表现出来,已成功解决,胎儿已经保存好了.神经影像学证实肿瘤完全切除,而神经病理学检查显示前庭神经鞘瘤。因此,我们建议对这些患者进行早期诊断和治疗,尤其是头痛的人,呕吐,怀孕期间突然听力损失。在这里,我们的结论是,我们的病例在最新可接受的时间框架内提供了宝贵的经验,为防止妊娠晚期不可逆的神经损伤和早产的手术提供了经验。
Vestibular schwannomas in pregnancy have rarely been reported, and there is a lack of in-depth discussion on the experience of management of massive acoustic neuromas in pregnancy. Herein, we present a pregnant woman with a giant vestibular schwannoma and obstructive hydrocephalus who presented at 30 weeks of gestation. She was initially misdiagnosed as having a pregnancy-related reaction of headache, dizziness, and vomiting that had occurred 2 months earlier. After observation at home, her symptoms progressed at 30 weeks of gestation, and imaging findings revealed a brain tumor in the CPA region with secondary cerebella tonsil herniation and obstructive hydrocephalus, and she was transferred to our center for treatment. Consequently, we relieved her hydrocephalus with a ventriculoperitoneal shunt (V-P shunt) and used corticosteroids to simulate fetal maturation. After 10 days, her mental condition deteriorated, and her right limb muscle strength gradually decreased until grade 0 (MMT Grading). Finally, under a joint consultation with the Department of Neurosurgery, Obstetrics, and Anesthesiology, she underwent a cesarean section under general anesthesia and first-stage tumor removal at 31 weeks of gestation. Upon discharge, the previously observed neurological deficits, which were reversible and had manifested during her gestational period, had been successfully resolved, and the fetus had been conserved. The neuroimaging confirmed the complete tumor removal, while the neuropathologic examination revealed a vestibular schwannoma. Therefore, we recommend early diagnosis and treatment for these patients, especially people with headaches, vomiting, and sudden hearing loss during pregnancy. Herein, we concluded that our cases provide a valuable experience in the latest acceptable time frame for the operation to prevent irreversible neurological impairment and premature delivery in late pregnancy.