vestibular rehabilitation

前庭康复
  • 文章类型: Journal Article
    前庭系统专用于凝视稳定,姿势平衡,和空间定位;这使得前庭功能对于我们与环境有效互动的能力至关重要。前庭功能减退(VH)随着时间的推移,它在早期和晚期表现不同。在VH的初始阶段,使用前庭康复治疗(VRT)减轻VH的影响,这可以借助技术来促进。在VH的更高级阶段,使用可穿戴技术进行感觉增强和感觉替代的新技术已应用于管理VH。尽管如此,在过去的几十年中,辅助技术在VH管理方面的潜力仍未得到充分开发.因此,在这篇评论文章中,我们介绍了促进早期VRT和管理高级VH的最先进技术。此外,提出了如何改进这些技术以实现长期门诊和家庭使用的挑战和策略。
    The vestibular system is dedicated to gaze stabilization, postural balance, and spatial orientation; this makes vestibular function crucial for our ability to interact effectively with our environment. Vestibular hypofunction (VH) progresses over time, and it presents differently in its early and advanced stages. In the initial stages of VH, the effects of VH are mitigated using vestibular rehabilitation therapy (VRT), which can be facilitated with the aid of technology. At more advanced stages of VH, novel techniques that use wearable technologies for sensory augmentation and sensory substitution have been applied to manage VH. Despite this, the potential of assistive technologies for VH management remains underexplored over the past decades. Hence, in this review article, we present the state-of-the-art technologies for facilitating early-stage VRT and for managing advanced-stage VH. Also, challenges and strategies on how these technologies can be improved to enable long-term ambulatory and home use are presented.
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  • 文章类型: Journal Article
    Large vestibular aqueduct syndrome(LVAS) is a common recessive hereditary hearing loss disease, and some patients may also experience vestibular dysfunction. With the wide application of cochlear implant(CI) and the development of vestibular medicine, the pathophysiological mechanism of LVAS and the influence mechanism of CI on vestibular function are gradually elucidated. Consequently, the evaluation and rehabilitation of vestibular dysfunction function have also become research hotspots. This article reviews studies on vestibular function and related rehabilitation in patients with large vestibular aqueduct syndrome.
    摘要: 大前庭水管综合征(large vestibular aqueduct syndrome,LVAS)是临床常见的常染色体隐性遗传性听力损失疾病,大部分患者可伴发前庭功能障碍。随着人工耳蜗植入(cochlear implant,CI)的广泛应用和前庭医学的发展,LVAS的病理、生理机制及CI对于前庭功能的影响得到了广泛关注,针对LVAS的前庭功能以及CI术后的前庭功能康复逐步成为研究热点,本文就LVAS患者的前庭功能及其相关康复研究做一综述。.
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  • 文章类型: Journal Article
    背景:短期个性化前庭康复(ST-PVR)可以建立稳定的前庭代偿。然而,对于能够动态反映前庭康复(VR)进展的临床指标,目前缺乏明确的定义.
    目的:探讨适合评价ST-PVR治疗良性复发性眩晕(BRV)疗效的临床指标。
    方法:总共,纳入50例诊断为BRV的患者。所有患者均接受ST-PVR治疗方案。康复后2周和4周,主观尺度,包括视觉模拟量表(VAS),头晕障碍量表(DHI),评估了特定活动平衡信心量表(ABC)和广泛性焦虑障碍(GAD-7).进行了客观的前庭功能测试。确定VR分级。
    结果:康复2周后,在VAS中观察到显著增强,DHI,ABC,GAD-7,UW,vHIT结果,和VR分级评分(p<0.05)。感觉组织测试(SOT)结果显示在康复后2周和4周的统计学显著改善(p<0.05)。
    结论:客观评估中的主观量表和部分检查结果均可作为动态监测BRV患者前庭功能代偿过程的指标。VR功效分级评分,其中包含了上述指标,允许量化在前庭康复过程中发生的变化。
    BACKGROUND: Short-term personalized vestibular rehabilitation (ST-PVR) can establish stable vestibular compensation. However, there is a lack of a clear definition for clinical indicators that can dynamically reflect the progress of vestibular rehabilitation (VR).
    OBJECTIVE: To explore the clinical indicators suitable for evaluating the effectiveness of ST-PVR in treating benign recurrent vertigo (BRV).
    METHODS: In total, 50 patients diagnosed with BRV were enrolled. All patients received the ST-PVR treatment program. At 2 and 4 weeks after rehabilitation, subjective scales, including the visual analogue scale (VAS), dizziness handicap inventory scale (DHI), activities-specific balance confidence scale (ABC) and generalized anxiety disorder (GAD-7) were assessed. Objective vestibular function tests were performed. VR grading was determined.
    RESULTS: At 2 weeks after rehabilitation, significant enhancements were observed in VAS, DHI, ABC, GAD-7, UW, vHIT results, and VR grading scores (p < 0.05). The sensory organization test (SOT) results demonstrated statistically significant improvements at 2 weeks and 4 weeks after rehabilitation (p < 0.05).
    CONCLUSIONS: Both subjective scales and partial examination results in objective assessment can serve as indicators to dynamically monitor the compensatory process of vestibular function in patients with BRV. The VR efficacy grading score, which incorporates the above indicators, allows for quantification of the changes that occur during the vestibular rehabilitation process.
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  • 文章类型: Journal Article
    本研究旨在探讨良性阵发性位置性眩晕(BPPV)成功重新定位后残留症状患者前庭康复(VR)的不同持续时间和每日频率的影响。
    成功进行BPPV重新定位的患者(n=118)根据VR持续时间和频率分为3组:A组(n=30;15分钟,3次/天),B组(n=30;30分钟,3次/天),C组(n=28;15分钟,6次/天),对照组D(n=30;无VR)。所有患者在基线以及2周和4周后完成头晕障碍量表(DHI)和前庭康复受益问卷(VRBQ)。
    2、4周后VRA~C组与对照D组的情感评分和重度头晕残疾在DHI评分中的比例差异均有统计学意义(均P<.05)。2、4周后VRA~C组的总DHI和VRBQ评分差异均有统计学意义(均P<0.05)。有趣的是,A组的情绪评分无显著差异(P=.385),B组(P=.569),和C组(P=0.340)在2和4周之间。同时在2周,A组和B组之间运动引起的头晕评分差异有统计学意义(P=.02).
    在成功的BPPV重新定位后,在常规治疗中,超过4周的总VR持续时间可以减少头晕并改善VR益处。2周后可观察到情绪改善。如果患者愿意考虑将持续时间增加到15分钟以上,VR可能有助于更早地缓解运动引起的头晕。
    UNASSIGNED: This study aimed to explore the effects of different duration and daily frequency of vestibular rehabilitation (VR) in patients with residual symptoms after benign paroxysmal positional vertigo (BPPV) successful repositioning.
    UNASSIGNED: Patients with successful BPPV repositioning (n = 118) were divided into 3 groups according to VR duration and frequency: group A (n = 30; 15 minutes, 3 times/day), group B (n = 30; 30 minutes, 3 times/day), group C (n = 28; 15 minutes, 6 times/day), and control group D (n = 30; no VR). All patients completed the dizziness handicap inventory (DHI) and vestibular rehabilitation benefit questionnaire (VRBQ) at baseline and after 2 and 4 weeks.
    UNASSIGNED: The emotional scores and the proportion of severe dizziness disability in the DHI scores were significant differences between VR groups A to C and control group D after 2 and 4 weeks (all P < .05). There were significant differences in total DHI and VRBQ scores among the VR groups A to C after 2 and 4 weeks (all P < .05). Interestingly, emotion scores were not significantly different in group A (P = .385), group B (P = .569), and group C (P = .340) between 2 and 4 weeks. Meanwhile at 2 weeks, the difference in motion-provoked dizziness score between group A and B was statistically significant (P = .02).
    UNASSIGNED: A total VR duration over 4 weeks can reduce dizziness and improve VR benefits in routine therapy in patients with residual dizziness after successful BPPV repositioning. Emotional improvement can be observed after 2 weeks. VR may help to relieve motion-provoked dizziness earlier if patients are willing to consider increasing the duration to more than 15 minutes.
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  • Bilateral vestibulopathy(BVP) is one of the common diseases in the vestibular nervous system, with an incidence rate of about 4%-7% in the population, which can lead to a variety of body dysfunctions. At present, there are two main treatment methods for BVP. One is vestibular rehabilitation. However, only part of BVP patients can finally benefit from vestibular rehabilitation, and most patients will remain with permanent vestibular dysfunction. Benefiting from the maturity of cochlear implant technology, European and American countries took the lead in the development of vestibular prosthesis(VP) technology to restore the vestibular function in patients with BVP. This review will focus on the development history, principles, future applications and the related research progress of VP in China.
    摘要: 双侧前庭病(bilateral vestibulopathy,BVP)为前庭神经系统常见疾病之一,人群发病率约为4%~7%,可导致多种机体功能障碍。目前对BVP的治疗方法主要有2种,一为前庭康复,然而仅有部分BVP患者可通过前庭康复最终获益,大部分患者将遗留永久性功能障碍。获益于人工耳蜗技术的成熟,欧美国家率先开始了人工前庭技术的研发,用以恢复BVP患者的前庭神经系统功能。本综述将着重介绍人工前庭的发展历史、工作原理、未来应用以及我国人工前庭的相关研究进展。.
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  • 文章类型: Meta-Analysis
    背景:支持使用前庭康复疗法(VRT)改善中风后患者的平衡和步态的证据有限。本系统评价旨在评估VRT除常规康复外,与常规康复相比,对改善卒中后患者平衡和步态的效果。
    方法:本综述遵循系统评价和Meta分析陈述指南的首选报告项目。截至2023年6月1日,共检索了十个电子数据库,没有语言和出版状态的限制。PEDro量表和建议评估发展分级,和评估用于评估偏倚风险和证据的确定性。使用ReviewManager5.3进行荟萃分析。
    结果:纳入了15项随机对照试验,共769名参与者。PEDro量表用于评估偏倚风险,平均得分为5.9(0.7)。VRT可有效改善卒中后患者的平衡(SMD=0.59,95%CI(0.40,0.78),p<0.00001),特别是卒中后发生在6个月内的患者(SMD=0.56,95%CI(0.33,0.79),p<0.00001),证据的确定性适中。亚组分析显示,VRT作为注视稳定性练习结合转椅训练提供(SMD=0.85,95%CI(0.48,1.22),p<0.00001)和头部运动(SMD=0.75,95%CI(0.43,1.07),p<0.00001)可以显著改善平衡。4周VRT对平衡改善效果较好(SMD=0.64,95%CI(0.40,0.89),p<0.00001)比小于4周的VRT。时间Up-and-Go检验值的合并均值差异显示VRT可以显着改善卒中后患者的步态功能(MD=-4.32,95%CI(-6.65,-1.99),p=0.0003),尤其是卒中后发生在6个月内的患者(MD=-3.92,95%CI(-6.83,-1.00),p=0.008),具有中等的证据确定性。
    结论:有证据支持VRT在改善卒中后患者平衡和步态方面的积极作用。
    背景:PROSPEROCRD42023434304。
    There is limited evidence to support the use of vestibular rehabilitation therapy (VRT) on improving balance and gait in patients after stroke. This systematic review aimed to evaluate the effects of VRT in addition to usual rehabilitation compared with usual rehabilitation on improving balance and gait for patients after stroke.
    This review followed the Preferred Reporting Items for Systematic reviews and Meta-Analysis statement guidelines. Ten electronic databases were searched up to 1 June 2023 without restrictions in language and publication status. The PEDro scale and the Grading of Recommendations Assessment Development, and Evaluation were used to evaluate the risk of bias and the certainty of evidence. The meta-analysis was conducted with Review Manager 5.3.
    Fifteen randomised controlled trials with 769 participants were included. PEDro scale was used to assess the risk of bias with a mean score of 5.9 (0.7). VRT was effective in improving balance for patients after stroke (SMD = 0.59, 95% CI (0.40, 0.78), p < 0.00001), particularly for patients after stroke that occurred within 6 months (SMD = 0.56, 95% CI (0.33, 0.79), p < 0.00001) with moderate certainty of evidence. Subgroup analysis showed that VRT provided as gaze stability exercises combined with swivel chair training (SMD = 0.85, 95% CI (0.48, 1.22), p < 0.00001) and head movements (SMD = 0.75, 95% CI (0.43, 1.07), p < 0.00001) could significantly improve balance. Four-week VRT had better effect on balance improvement (SMD = 0.64, 95% CI (0.40, 0.89), p < 0.00001) than the less than 4-week VRT. The pooled mean difference of values of Timed Up-and-Go test showed that VRT could significantly improve gait function for patients after stroke (MD =  -4.32, 95% CI (-6.65, -1.99), p = 0.0003), particularly for patients after stroke that occurred within 6 months (MD =  -3.92, 95% CI (-6.83, -1.00), p = 0.008) with moderate certainty of evidence.
    There is moderate certainty of evidence supporting the positive effect of VRT in improving balance and gait of patients after stroke.
    PROSPERO CRD42023434304.
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  • 文章类型: Journal Article
    UNASSIGNED:这是一项分组随机对照研究,旨在评估前庭-眼反射(VOR)适应训练对复发性眩晕伴单侧前庭功能障碍(UVD)和正常平衡功能的儿童的有效性和接受度。
    未经批准:30个孩子,4-13岁,分析诊断为儿童复发性眩晕(RVC)的UVD(根据热量测试)和正常平衡功能。根据相似的年龄和眩晕的严重程度,将这30名儿童分为10个街区。每个组的3名儿童被随机分配到三组中的一组,接受1个月的治疗。A组接受前庭眼反射(VOR)适应训练,B组接受了Cawthorne-Cooksey训练,对照组没有接受训练。所有儿童均接受药物治疗[银杏叶提取物(滴剂)]。头晕障碍清单(DHI),眩晕患者生活质量视觉模拟量表(VAS-QLV),并在治疗前后进行热量测试(CP)记录,并对治疗效果进行评价。采用视觉接受模拟量表(VAS-A)评价两组接受训练的接受情况。
    未经评估:A组各有10名儿童,B组,和对照组;男女比例为1,各组平均年龄为9.0±3.2,8.4±3.0,8.3±2.6岁,分别。A组有效率100%,B组65%,C组60%。处理后的热量测试回收率为100%,70%和50%,分别。A组训练前后DHI评分分别为56.8±12.4和8.8±6.1,B组57.8±12.6和18.8±9.7,C组分别为56.8±12.4和24.0±15.3(P均=0.000)。A组训练前后VAS-QLV评分分别为7.5±1.0和0.9±0.9,B组6.4±2.2和2.7±1.1,C组分别为6.6±1.6和2.6±1.4(均P<0.05)。A组训练前后CP值分别为35.7±15.1和12.9±8.7,B组33.6±20.1和23.6±19.3,C组38.6±21.1和24.8±17.9(分别为P=0.001,P=0.015和P=0.050)。组间比较显示,训练后DHI和VAS-QLV评分的降低有显著性差异(P=0.015,P=0.02),而CP值没有(P=0.139)。培训后,与C组相比,A组DHI值明显下降(P<0.05),但是没有其他区别。培训后,与B、C组比较,A组VAS-QLV评分下降更明显(P<0.05)。在接受方面,A组VAS-A评分为7.6±2.2,B组为3.1±2.8(P=0.004),A组接受率为70%,B组接受率为10%,A组和B组年龄与VAS-A无明显相关性(P>0.05)。
    UNASSIGNED:这项研究强烈建议对眩晕患儿进行前庭康复训练以改善症状。对于患有UVD但平衡功能正常的RVC的儿童,单一的VOR适应方案可以有效改善眩晕症状,考虑到它的简单性,时效,和出色的结果,与经典的Cawthorne-Cooksey训练相比,它与儿童更好的接受度有关。
    UNASSIGNED: This was a block randomized controlled study to evaluate the effectiveness and acceptance of Vestibulo-Ocular Reflex (VOR) adaptation training in children with recurrent vertigo with unilateral vestibular dysfunction (UVD) and normal balance function.
    UNASSIGNED: Thirty children, aged 4-13 years, diagnosed with recurrent vertigo of childhood (RVC) with UVD (according to a caloric test) and normal balance function were analyzed. These 30 children were divided into 10 blocks based on similar age and severity of vertigo. Three children in each block were randomly assigned to one of three groups to receive 1 month of treatment. Group A received vestibular-ocular reflex (VOR) adaptation training, Group B received Cawthorne-Cooksey training, and a control group received no training. All children were administered pharmacotherapy [Ginkgo biloba leaf extract (drops)]. The Dizziness Handicap Inventory (DHI), Visual Analog Scale of Quality of Life with Vertigo (VAS-QLV), and canal paralysis (CP) on the caloric test were recorded before and after treatment, and the effectiveness of treatment was evaluated. The Visual Analog Scale of Acceptance (VAS-A) was used to evaluate the acceptance of the training in the two groups that received training.
    UNASSIGNED: There were 10 children each in Group A, Group B, and the control group; the male to female ratio was 1, and the average age in each group was 9.0 ± 3.2, 8.4 ± 3.0, and 8.3 ± 2.6 years, respectively. The effective rate was 100% in Group A, 65% in Group B, and 60% in Group C. The recovery rate on caloric testing after treatment was 100, 70, and 50%, respectively. DHI scores before and after training were 56.8 ± 12.4 and 8.8 ± 6.1 in Group A, 57.8 ± 12.6 and 18.8 ± 9.7 in Group B, and 56.8 ± 12.4 and 24.0 ± 15.3 in Group C (all P = 0.000). VAS-QLV scores before and after training were 7.5 ± 1.0 and 0.9 ± 0.9 in Group A, 6.4 ± 2.2 and 2.7 ± 1.1 in Group B, and 6.6 ± 1.6 and 2.6 ± 1.4 in Group C (all P < 0.05). The CP values before and after training were 35.7 ± 15.1 and 12.9 ± 8.7 in Group A, 33.6 ± 20.1 and 23.6 ± 19.3 in Group B, and 38.6 ± 21.1 and 24.8 ± 17.9 in Group C (P = 0.001, P = 0.015, and P = 0.050, respectively). Between-group comparisons showed that the decreases in DHI and VAS-QLV scores after training were significantly different (P = 0.015, P = 0.02), while CP values were not (P = 0.139). After training, the DHI value had decreased significantly more in Group A compared with Group C (P < 0.05), but there were no other differences. After training, VAS-QLV scores in Group A had decreased significantly more compared with Group B and C (P < 0.05). In terms of acceptance, the VAS-A score was 7.6 ± 2.2 in Group A and 3.1 ± 2.8 in Group B (P =0.004), The acceptance rate was 70% in group A and 10% in group B. there was no significant correlation between age and VAS-A in either group A or group B (P > 0.05).
    UNASSIGNED: This study strongly suggests that vestibular rehabilitation training should be performed in children with vertigo to improve symptoms. For children with RVC with UVD but normal balance function, a single VOR adaptation program can effectively improve vertigo symptoms, and given its simplicity, time-effectiveness, and excellent outcomes, it is associated with better acceptance in children compared to classic Cawthorne-Cooksey training.
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  • 文章类型: Journal Article
    本研究旨在探讨注视稳定练习(GSEs)对步态的影响,足底压力,卒中后患者(≤6个月)的平衡功能。将40例脑卒中后患者随机分为实验组(n=20)和对照组(n=20)。实验组进行GSEs联合物理治疗,而对照组只进行物理治疗,一天一次,一周五天,4周。Berg平衡量表(BBS)用于测试平衡功能和跌倒风险,这是主要结果。定时上行和下行测试(TUGT)评估了步行能力和跌倒风险。采用包络线椭圆面积和患侧足底压力比例测量患者静立时的支撑能力和稳定性。压力位移速度的前后中心用于测试重量移位能力。与对照组相比,受影响侧的摆动阶段,摆动相位的绝对对称指数,闭眼时的包络椭圆区域,实验组GSEs后TUGT明显下降(p<0.05);BBS评分,TUGT,前后COP位移速度,训练4周后患侧足底压力比例明显升高(p<0.05)。总之,GSE联合物理治疗可改善脑卒中后患者的步态和平衡功能。此外,它可以增强患侧的重量转移和单腿站立能力,从而降低跌倒的风险。
    This study aims to explore the effects of gaze stabilization exercises (GSEs) on gait, plantar pressure, and balance function in post-stroke patients (≤6 months). Forty post-stroke patients were randomly divided into an experimental group (n = 20) and a control group (n = 20). The experimental group performed GSEs combined with physical therapy, while the control group only performed physical therapy, once a day, 5 days a week, for 4 weeks. The Berg Balance Scale (BBS) was used to test the balance function and the risk of falling, which was the primary outcome. The Timed Up and Go test (TUGT) evaluated the walking ability and the fall risk. The envelope ellipse area and the plantar pressure proportion of the affected side were used to measure the patient’s supporting capacity and stability in static standing. The anterior−posterior center of pressure displacement velocity was used to test the weight-shifting capacity. Compared to the control group, the swing phase of the affected side, swing phase’s absolute symmetric index, envelope ellipse area when eyes closed, and TUGT of the experimental group had significantly decreased after GSEs (p < 0.05); the BBS scores, TUGT, the anterior−posterior COP displacement velocity, and the plantar pressure proportion of the affected side had significantly increased after 4 weeks of training (p < 0.05). In conclusion, GSEs combined with physical therapy can improve the gait and balance function of people following stroke. Furthermore, it can enhance the weight-shifting and one-leg standing capacity of the affected side, thus reducing the risk of falling.
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  • 文章类型: English Abstract
    Objective:To evaluate the value of high intensity stimulation training of semicircular canal of SRM-Ⅳ vertigo diagnosis and treatment system in the rehabilitation of vestibular neuritis. Methods:To analyze 68 patients with vestibular neuritis treated in Department of Otorhinolaryngology Head and Neck Surgery, Shijiazhuang People\'s Hospital from January 2020 to January 2021, conduct spontaneous nystagmus and head toss test, and perform spontaneous nystagmus and rotation test of SRM-Ⅳvertigo system, compare the positive rate of the side of disease was between the two. To randomly divide 68 patients into treatment group 1, 2 and control group, the control group with drugs, treatment group 1 with drugs and vestibular rehabilitation training exercise, treatment group 2 with additional high intensity stimulation training of semicircular canal at one week after onset, on the basis of drug therapy and vestibular rehabilitation training exercise. At 2 weeks and 1 month, through swivel chair test negative rate, DHI score, compare the efficacy of the three groups. Results:Spontaneous nystagmus combined with head toss test confirmed 80.9% of the side of the disease, spontaneous nystagmus and rotation test of SRM-Ⅳ vertigo system confirmed 100%, the difference is statistically significant(P<0.05). Compared with the control group and the treatment group 1, the negative conversion rate of the rotation test in the treatment group 2 at the second week and the first month of treatment, the difference is statistically significant(P<0.05, the second week χ²=6.474, the first month χ²=6.245); the DHI score of treatment group 2 was statistically significant compared with that of control group and treatment group 1 at the second week and first month of treatment(P<0.05, the second week F=13.578, the first month F=28.599). Conclusion:SRM-Ⅳ vertigo diagnosis and treatment system semicircular canal high intensity stimulation training has a certain role in the rehabilitation treatment of vestibular neuritis. It is simple to operate, patient tolerance and compliance are good, and it is worth promoting.
    目的:评价SRM-Ⅳ眩晕诊疗系统半规管高强刺激训练在前庭神经炎康复治疗中的价值。 方法:对2020年1月—2022年1月在石家庄市人民医院耳鼻咽喉头颈外科治疗的68例前庭神经炎患者,进行自发眼震、甩头试验以及SRM-Ⅳ眩晕诊疗系统的自发眼震、旋转试验检查。将68例患者随机分为对照组、治疗1组、治疗2组。对照组应用药物治疗,治疗1组给予药物治疗和前庭康复训练,治疗2组在药物治疗、前庭康复训练基础上,于发病1周后增加半规管高强刺激训练。3组分别在治疗2周、1个月时,通过旋转试验转阴率、DHI评分进行疗效比较。 结果:自发眼震结合甩头试验检查明确发病侧别80.9%,经SRM-Ⅳ眩晕诊疗系统的自发眼震和旋转试验检查明确发病侧别100%,差异有统计学意义(P<0.05);治疗2组在治疗2周、1个月旋转试验转阴率与对照组和治疗1组比较,差异均有统计学意义(P<0.05、2周χ²=6.474、1个月χ²=6.245);治疗2组在治疗2周、1个月DHI评分与对照组和治疗1组比较,差异均有统计学意义(P<0.05、2周F=13.578、1个月F=28.599)。 结论:SRM-Ⅳ眩晕诊疗系统半规管高强刺激训练在前庭神经炎康复治疗中具有一定的作用,其操作简单,患者耐受性、依从性好,值得临床推广。.
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  • 文章类型: Journal Article
    Objective:To observe the effectiveness of vestibular rehabilitation in Ménière\'s disease patients with chronic imbalance. Methods:Forty-five Ménière\'s disease patients with chronic imbalance treated in vertigo specialist clinic of Eye and ENT Hospital of Fudan University from December 2020 to December 2021 were enrolled. Patients were divided randomly into two groups, 23 patients in experimental group and 22 patients in control group. Both groups received routine outpatient treatment, and the experimental group received an additional vestibular rehabilitation for 8 weeks. All patients were evaluated with dizziness handicap inventory (DHI) at baseline and 8-week follow-up, and the incidence of fall was calculated. The occurrence of adverse events during the study was also recorded. Results:There was no significant difference in baseline data between the two groups (P>0.05). During the study, 1 patient were lost to follow-up and 2 patients dropped out. A total of 42 patients completed the study. Intentionality analysis was performed on lost follow-up patients. After 8 weeks of the treatment, there were significant statistically differences in difference values of DHI and DHI-F scores(d₁=-30.22±3.78, d₂=-13.09±4.85, t=-2.799, P<0.05; d₁=-12.43±1.46, d₂=-4.55±2.17, t=-3.043, P<0.05), while no significant difference was showed in the difference values of DHI-P and DHI-E scores(P>0.05). There was no significant difference in incidence of fall between two groups(P>0.05), but the incidence of experimental group decreased significantly compared with that before treatment(4.35% vs 34.78%, χ²=4.973, P<0.05). No serious adverse event was reported in the two groups. Conclusion:Vestibular rehabilitation can improve the balance function and reduce risk of fall in Ménière\'s disease patients with chronic imbalance. Therefore, it is worthy of clinical application.
    目的:观察前庭康复在梅尼埃病慢性失衡患者中的疗效。 方法:入组2020年12月—2021年12月在复旦大学附属眼耳鼻喉科医院眩晕专科门诊就诊的45例梅尼埃病慢性失衡患者,采用随机数表的方法将患者分为试验组(23例)和对照组(22例)。对照组接受门诊常规治疗,试验组在常规治疗的基础上接受为期8周的前庭康复训练。在基线和治疗8周时使用眩晕残障量表(DHI)对所有患者进行评估,计算两组患者的跌倒发生率并记录研究窗口期内的不良事件。 结果:两组患者基线资料差异无统计学意义(P>0.05)。研究过程中,有2例患者退出研究,1例患者失访,共42例患者完成试验。对失访患者进行意向性分析。经过8周治疗,两组患者的DHI和DHI-F得分差值的差异有统计学意义(d₁=-30.22±3.78,d₂=-13.09±4.85,t=-2.799,P<0.05;d₁=-12.43±1.46,d₂=-4.55±2.17,t=-3.043,P<0.05),DHI-P和DHI-E得分差值的差异无统计学意义(P>0.05)。两组患者的跌倒发生率差异无统计学意义(P>0.05),但治疗后试验组的跌倒发生率已较治疗前显著下降(4.35% vs 34.78%,χ²=4.973,P<0.05)。两组均未报告严重不良事件。 结论:前庭康复能够改善梅尼埃病慢性失衡患者的平衡功能,降低患者的跌倒风险,值得临床上推广应用。.
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