■为了评估可行性,功效,微波消融治疗滤泡性甲状腺肿瘤和可疑滤泡性甲状腺肿瘤的安全性。
■在这项回顾性研究中,总结2016年12月至2024年1月微波消融治疗滤泡性肿瘤的患者资料.结节大小的变化,volume,技术成功率,疾病进展,完整的肿瘤分辨率,甲状腺功能,并对消融后的并发症进行了评估。
■74名患者(15名男性,包括59名女性;平均年龄46.3±15.2岁)的滤泡性肿瘤。在13个月的中位随访时间内,实现了完全消融,给出100%的技术成功率。在消融后的第一个月,结节最大直径无明显变化(p=0.287)。从第三个月开始,最大直径和体积均显着降低(全部p<0.005)。体积减少率在1个月和3个月保持稳定(分别为p=0.389和0.06),但此后显着增加(全部p<0.005)。到24个月,中值最大直径从2.3厘米减少到0厘米,实现100%的中位体积减少率。20.3%(15/74)的结节完全消失。2.7%的病例出现局部复发(2/74),无转移或肿瘤相关死亡报告。治疗后甲状腺功能无变化(p>0.05)。并发症和副作用发生率分别为8.1%和4.1%,分别。
■初步研究结果表明,微波消融治疗滤泡性肿瘤是一种安全有效的治疗方法,疾病进展和并发症发生率低,同时保持甲状腺功能。
UNASSIGNED: To assess the feasibility, efficacy, and safety of microwave ablation in treating follicular thyroid neoplasms and suspicious follicular thyroid neoplasms.
UNASSIGNED: In this retrospective study, the data of patients treated with microwave ablation for follicular neoplasms from December 2016 to January 2024 were summarized. The changes in nodule size, volume, technical success rate, disease progression, complete tumor resolution, thyroid function, and complications post-ablation were evaluated.
UNASSIGNED: Seventy-four patients (15 men, 59 women; mean age 46.3 ± 15.2 years) with follicular neoplasms were included. Over a median follow-up of 13 months, complete ablation was achieved, giving a 100% technical success rate. At the first month post-ablation, the maximum diameter of nodules showed no significant change (p = 0.287). From the third month, both maximum diameter and volume significantly decreased (p < 0.005 for all). Volume reduction rates remained stable at one and three months (p = 0.389 and 0.06, respectively) but increased significantly thereafter (p < 0.005 for all). By 24 months, the median maximum diameter had reduced from 2.3 cm to 0 cm, achieving a median volume reduction rate of 100%. Nodules disappeared completely in 20.3% (15/74). Local recurrence was noted in 2.7% of cases (2/74), with no metastasis or neoplasm-related deaths reported. Thyroid function remained unchanged post-treatment (p > 0.05). The complication and side effect rates were 8.1% and 4.1%, respectively.
UNASSIGNED: Initial findings suggest microwave ablation is an effective and safe treatment for follicular neoplasms, with low incidences of disease progression and complications, while maintaining thyroid function.