数以百万计的公共共享单车(PSB)已经在中国推出,和PSB是抗微生物耐药葡萄球菌的潜在储库。然而,没有国家数据来阐明传播,在中国不同城市的公共共享单车中,已经恢复了葡萄球菌的耐药性和基因型。抗菌药物敏感性,确定了葡萄球菌的SCCmec类型和序列类型。本研究共回收了146株葡萄球菌,87%的葡萄球菌分离株对至少一种抗生素耐药。总的来说,29株(20%)葡萄球菌分离株携带mecA基因,和SCCmec类型确定如下:SCCmecII型(n=1),IV(n=3),V(n=4),VI(n=1),VIII(n=2),A/1(n=6),A/5(n=2),C/1(n=2),C/2(n=1),C/3(n=1),(n=5)和伪(Φ)-SCCmec(n=1)。确定了16种表皮葡萄球菌的序列类型,包括ST10、ST17、ST59、ST60、ST65、ST130、ST184、ST262、ST283、ST337、ST360、ST454、ST567、ST820、ST878和ST934。PSBs是不同的抗微生物葡萄球菌的储库,在中国南方和北方从公共共享自行车中回收的分离物中观察到葡萄球菌种类差异。PSB是抗微生物耐药性和遗传多样性葡萄球菌的来源。
Millions of public shared bicycles (PSBs) have been launched in
China, and PSBs are a potential reservoir of antimicrobial-resistant
staphylococci. However, no national data to elucidate the dissemination, antimicrobial resistance and genotypes of staphylococci has been recovered from public shared bicycles located in different cities in
China. Antimicrobial susceptibility, SCCmec types and sequence types of staphylococci were determined. A total of 146 staphylococci were recovered in this study, and 87% staphylococcal isolates were resistant to at least one antibiotic. In total, 29 (20%) staphylococcal isolates harbored mecA gene, and SCCmec types were determined as follows: SCCmec type II (n = 1), IV(n = 3), V (n = 4), VI (n = 1), VIII (n = 2), A/1 (n = 6), A/5 (n = 2), C/1 (n = 2), C/2 (n = 1), C/3 (n = 1), (n = 5) and Pseudo (ψ)-SCCmec (n = 1). Sequence types of 16 Staphylococcus epidermidis were determined, including ST10, ST17, ST59, ST60, ST65, ST130, ST184, ST262, ST283, ST337, ST360, ST454, ST567, ST820, ST878 and ST934. PSBs are a reservoir of diverse antimicrobial-resistant staphylococci, and staphylococcal species differences were observed in isolates that were recovered from public shared bicycles in the south and north of
China. PSBs are a source of antimicrobial resistance and genetic diverse
staphylococci.