■恶性高热(MH)是一种高死亡率的高代谢综合征。早期发现和及时静脉注射丹曲林对于有效治疗MH至关重要。然而,目前缺乏全面的全国范围内的dantroene和麻醉医师对中国MH的了解。
■在2022年1月至2022年6月之间进行了全国性调查。通过社交平台向中国大陆麻醉医师发送了中国麻醉医师对MH认知的在线调查问卷。有关参与者对MH相关知识的感知的数据,国内丹曲林的可用性,本研究收集了报告的MH病例。
■共收集了来自中国大陆31个省的11,354名麻醉医师的回答。在11个得分问题中,关于MH的治疗药物(99.3%)和MH的特征(98.0%)的问题的准确率最高.相反,与MH最早的临床体征有关的问题的准确率最低(23.5%).不同职称之间的分数存在显着差异(P=0.003),学历(P<0.001),医院分类(P<0.001),和城市等级(P<0.001)。在受访者中,919名(8.1%)麻醉师报告说,他们的医院有丹曲林,631(5.6%)表示不清楚。在这项调查中,共有136家医院报告了至少一例先前的MH病例。
■中国大陆面临挑战,例如诊断和治疗MH的经验不足,以及获得丹曲林的困难。为了提高公众对MH的认识,建立和推广精细化MH培训体系势在必行。此外,应实施简化和快速的丹曲林联动应急系统,以确保迅速获得药物。
UNASSIGNED: Malignant hyperthermia (MH) is a hypermetabolic syndrome with high mortality rates. Early detection and prompt intravenous administration of dantrolene are crucial for effective management of MH. However, there is currently a lack of comprehensive nationwide surveys on the availability of dantrolene and anesthesiologists\' understanding of MH in
China.
UNASSIGNED: A nationwide survey was conducted between January 2022 and June 2022. Online questionnaires on the cognition of MH among anesthesiologists in
China were sent through social platforms to anesthesiologists in mainland
China. Data regarding participants\' perception of MH-related knowledge, availability of domestic dantrolene, and reported MH cases were collected in this study.
UNASSIGNED: Responses were collected from a total of 11,354 anesthesiologists representing 31 provinces across the Chinese mainland. Among the 11 scoring questions, the highest accuracy rates were observed for the question regarding therapeutic drugs for MH (99.3%) and the characteristics of MH (98.0%). Conversely, the question pertaining to the earliest clinical signs of MH had the lowest accuracy rate (23.5%). Significant variations were observed in the scores among different professional titles (P=0.003), academic degree (P<0.001), hospital classification (P<0.001), and urban hierarchy (P<0.001). Of the respondents, 919 (8.1%) anesthesiologists reported dantrolene availability in their hospitals, and 631 (5.6%) indicated unclear. A total of 136 hospitals in this survey reported at least one previous case of MH.
UNASSIGNED: Mainland
China faces challenges such as insufficient experience in diagnosing and treating MH, as well as difficulty in obtaining dantrolene. To improve the public awareness of MH, it is imperative to establish and promote a refined MH training system. Additionally, a streamlined and rapid dantrolene linkage emergency system should be implemented to ensure prompt access to the drug.