暂无摘要。

OBJECTIVE: The objective of this study was to evaluate the clinical effect and safety of the postauricular infratemporal fossa approach (ITFA) in resecting jugular foramen lesions.
METHODS: All 25 patients undergoing microsurgery via postauricular ITFA from March 2015 to May 2023 in the Department of Neurosurgery, Tangdu Hospital, Air Force Military Medical University were included. The clinical and radiological data were retrospectively analyzed. Regular follow-up was carried out.
RESULTS: The mean age of all patients was 50.5±8.9 years, and 14 of them were female and 11 were male. Among the cases, lower cranial nerve schwannoma accounted for 60 % (15/25) of all tumors, jugular foramen paraganglioma accounted for 20 % (5/25), and the remaining 20 % included meningioma, chondrosarcoma, plasmacytoma, and salivary gland tumors. Total tumor resection was performed in 18 cases, subtotal tumor resection in 7 cases and partial resection in 1 case. Seven patients underwent gamma knife radiotherapy after surgery. Transient lower cranial nerve dysfunction occurred in 8 patients, and permanent lower cranial nerve dysfunction occurred in 2 patients after surgery. One patient developed facial paralysis, and one patient presented hearing loss.
CONCLUSIONS: The postauricular ITFA achieved a relatively high total tumor resection rate and a lower incidence of neurological functional disorders. It is an alternative and suitable surgical approach for resecting jugular foramen lesions. Maximizing the preservation of neurological function is preferred, especially when radical resection cannot be achieved. Stereotactic radiotherapy could be used for residual tumors.

Neoplasms in the infratemporal fossa (ITF) are rare and insidious lesions that cause various symptoms due to involvement of the temporomandibular joint (TMJ), paranasal sinuses, and orbit. Here, we report a case of metastatic non-small cell lung adenocarcinoma in the ITF. The patient presented with facial pain and limited mouth opening, which did not respond to treatment for TMJ disorder, and a neoplasm was discovered in the ITF through medical imaging. With an open biopsy, the diagnosis was finalized. This report suggested that the physician should consider lesions in the ITF when facial pain and limited mouth opening failed local treatment, and distant metastasis of malignant tumor should be alerted. We also reviewed the literature regarding metastatic cancer to the ITF.

Objective: To investigate the efficacy and safety of endoscopic resection of infratemporal fossa mass and to determine the indications for surgery. Methods: A retrospective case series study was conducted, including a total of 29 patients who underwent endoscopic surgery to treat infratemporal fossa mass in the Department of Rhinology of Beijing Tongren Hospital, Capital Medical University, from April 2008 to December 2021. Ten males and 19 females were included in the study, with age of (46.5±13.7) years. Pre-and post-operative sinus CT, sinus or nasopharyngeal enhanced MRI were evaluated, respectively. The main outcome measurements were the total resection of mass and the incidence of surgery-related complications. Results: Among the 29 cases of infratemporal fossa mass, 22 were schwannomas, 3 were cysts, 2 were neurofibromas, 1 was pleomorphic adenoma and 1 was basal cell adenoma. Preoperative imaging showed well-defined lesion boundaries, and postoperative pathology confirmed the benign nature of all cases. The endoscopic transnasal approach was used in 28 patients, while the combination of the transnasal approach and the transoral approach was used in 1 patient. Complete tumor removal was achieved in all cases with a 100% resection rate. The average follow-up time was 38 months (7-168 months), and no tumor recurrence was observed. Conclusions: The Endoscopic transnasal approach is a safe and effective surgical approach for the treatment of benign tumors or masses in the infratemporal fossa.
目的： 分析内镜下手术治疗颞下窝肿物的疗效和安全性。 方法： 本研究为回顾性病例系列研究，纳入于2008年4月至2021年12月在首都医科大学附属北京同仁医院鼻科接受内镜手术治疗的颞下窝肿物患者29例，其中男性10例，女性19例，年龄（46.5±13.7）岁。术前和术后分别行鼻窦CT、鼻咽或鼻窦增强MRI评估。主要结局测量指标为肿物全部切除率，以及手术相关并发症发生情况。 结果： 本研究29例颞下窝肿物包含神经鞘瘤22例、囊肿3例、神经纤维瘤2例、多形性腺瘤1例、基底细胞腺瘤1例。术前影像学检查提示肿物周围界限清晰，术后组织病理学检查均提示为良性病变。28例患者采用内镜经鼻入路，1例采用内镜经鼻入路联合内镜经口入路，肿物全部切除率为100%。平均随访时间38个月（7~168个月），未见肿物复发。 结论： 内镜经鼻入路可用于切除颞下窝良性肿物，疗效满意且安全性较高。.

UNASSIGNED: In this paper, the goal of the authors is to present the anatomic nuances and their clinical experience with lesions of the pterygopalatine fossa and infratemporal fossa using an endoscopic transnasal prelacrimal recess transmaxillary approach (PLRMA).
UNASSIGNED: An endoscopic anatomical dissection of three fresh cadaveric heads was performed bilaterally to evaluate the feasibility of the PLRMA. Prior to dissection, stereotactic computed tomography scans were obtained for each head to obtain anatomical measurements. The area of exposure on the posterior wall of the maxillary sinus was determined using stereotaxis. The cases of six patients with schwannomas or epidermoid cysts who underwent the transnasal PLRMA were illustrated.
UNASSIGNED: The mean area of exposure on the posterior wall of the maxillary sinus was 9.55 cm2. Total resection was achieved in all six patients. The mean follow-up time was 16 months, and one patient complained of postoperative facial numbness, which resolved gradually. No cases of chronic sinusitis were reported.
UNASSIGNED: The endoscopic transnasal PLRMA provides efficient operative exposure to the pterygopalatine fossa and infratemporal fossa. Preserving the integrity of the mucosa on the nasal lateral wall is an advantage of this approach.

Objectives: Infratemporal fossa approaches (IFAs) allow the total resection of certain lateral skull base neoplasms. To date, no studies have explored the change of patient-reported quality of life (QoL) after total resection of benign lateral skull base neoplasms through IFA. The present study aimed to give a comprehensive understanding of QoL among patients after IFA through general and disease-specific QoL questionnaires. Methods: Forty-seven patients with benign lateral skull base neoplasms were enrolled. The Short Form 36 (SF-36), World Health Organization Quality of Life-BREF (WHOQOL-BREF), and the University of Washington Head and Neck Quality of Life (UW-QOL) were chosen as tools to assess QoL before and after surgeries through IFA. Results: Patients had significantly lower scores in appearance, chewing, and speech after surgeries through IFA. However, change in health from SF-36 and physical health from WHOQOL-BREF scored higher after surgery. In multivariate linear regression analysis, age, gender, mood, speech, appearance, swallowing, and chewing contributed independently to general QoL. Conclusion: Patients were shown to benefit with regard to overall QoL after gross tumor resection from IFA, despite the impact of appearance, speech, and chewing. Function preservation and restoration are critical since their correlation with postoperative QoL.

BACKGROUND: The treatment of abscess in the infratemporal space is still controversial and bedside and operative intraoral drainage is often used to resolve the abscess. However, it can be difficult to control the infection quickly.[1] In this report, the authors present a new technique of using transfixion irrigation with negative pressure drainage for minimally invasive management of infratemporal fossa abscess.
METHODS: A 45-year-old man with type 2 diabetes complained of painful swelling and trismus in the right lower facial region for 10 days. The patient was weak, with mild anxiety, and gradually aggravated.
METHODS: The patient was misdiagnosed and received dental pulp treatment for the right mandibular first molar and was given oral cefradine capsules (500 mg 3 times per day). Computed tomography scan and puncture revealed an abscess in the infratemporal fossa.
METHODS: The authors used transfixion irrigation with negative pressure drainage from different directions to reach the abscess cavity. Saline solution was infused through 1 tube and allowed to flow out through the other tube to flush out the pus and debris from the abscess.
RESULTS: On day 9, the drainage tube was removed and the patient was discharged. One week later, the patient was followed up in the outpatient clinic and the impacted mandibular third molar was removed. This technique is less invasive and leads to faster recovery times and fewer complications.
UNASSIGNED: The report highlights the importance of proper preoperative evaluation, using a thoracic drainage tube as soon as possible, and continuous flushing. A double-lumen drainage tube with a suitable diameter and combined flushing should be designed for future reference. Moreover, the use of drugs can effectively eliminate emboli formation, allowing for faster and more minimally invasive control and removal of the infection.[2].

This study aimed to introduce and evaluate the feasibility of a modified transzygomatic approach with preservation of masseter attachment for the management of infratemporal fossa tumors. This retrospective study included 20 patients treated at Shanghai Ninth People\'s Hospital, Shanghai Jiao Tong University, between June 2007 and August 2017. Pre- and postoperative radiological findings (magnetic resonance imaging and computed tomography) were obtained from all patients. During an average 67 months of follow-up, no clinical or radiographic signs were found of recurrence or absorption of zygomatic arch defects. The mean visual analog scale score changed from 5.5 preoperatively to 0.6 postoperatively (P<0.001), while the mean maximum inter-incisal opening improved from 21.5 mm preoperatively to 38.7 mm postoperatively (P<0.001). Thus, managing infratemporal lesions using the modified transzygomatic approach may provide functional and esthetically established outcomes.

滑膜肉瘤是一种具有间叶和上皮双相性分化的恶性肿瘤，在细胞遗传学上存在X与18号染色体的特异性易位，滑膜肉瘤可发生在任何部位，发生于颞下窝部位则罕见。根据组织学形态可分为双相分化型、梭形细胞型、单相上皮型和低分化（圆形细胞）型四型，其中单相上皮型、低分化型是较为少见的亚型。本文报道1例颞下窝滑膜肉瘤，经确诊后行肿瘤边缘广泛切除，术后随访6个月未复发。.

Objective:According to the characteristics of endoscopic transnasal and transoral surgery for infratemporal fossa tumors, we divided and named subzones of the infratemporal fossa, to explore the approaches of endoscopic transnasal and transoral surgery for infratemporal fossa tumors, and to analyze their advantages and disadvantages. Methods:We retrospectively analyzed the clinical data of 36 patients with benign tumors of infratemporal fossa successfully resected through nose or mouth under endoscope, summarized and analyzed the localization characteristics of these tumors in infratemporal fossa, and made a subzone naming rule of infratemporal fossa. We also summarized the selection principles, advantages and disadvantages of endoscopic transnasal and transoral surgical approaches. Results:The infratemporal fossa area is divided into ABC area. Area A is the fat pad area posterolateral of maxillary sinus. Area B is further divided into B1 （above the plane of maxillary sinus floor, anterior styloid process）, B2 （below the plane of maxillary sinus floor, anterior styloid process）, and B3 （posterior styloid process to anterior vertebra）; Area C is retropharyngeal and eustachian tube area. The location of the tumor in the infratemporal fossa determines the choice of transnasal and transoral approaches. All tumors were completely removed, and no tumor recurred during the follow-up. A few patients had temporary local sensory function decline, and recovered during the follow-up. Conclusion:The infratemporal fossa region naming rule according to the characteristics of endoscopic transoral and transnasal surgery approach is simple and practical, which can effectively guide the operation of the infratemporal fossa region and has clinical application value.
目的：根据内镜下经鼻和经口进行颞下窝肿瘤手术的特点进行颞下窝分区，探索内镜下经鼻和经口颞下窝肿瘤切除手术的径路选择，并分析其优缺点。 方法：回顾分析36例内镜下经鼻和经口成功切除颞下窝良性肿瘤患者资料，分析肿瘤在颞下窝区域定位特点，对颞下窝进行系统定位分区研究。总结内镜下经鼻和经口手术径路的选择原则及其优缺点。 结果：将颞下窝区域分为ABC区，A区为上颌窦后外侧脂肪区；B区进一步分为B1（上颌窦底壁平面上方，茎突前方），B2（上颌窦底壁平面下方，茎突前方），B3区（茎突后方至椎前）；C区为咽后及咽鼓管区。根据肿瘤主体在颞下窝分区中的定位特点，选择经鼻和经口入路。肿瘤均获完全切除，随访期间无肿瘤复发。少数患者出现局部感觉功能下降，随访期间均有所恢复。 结论：根据内镜下口鼻手术入路特点命名的颞下窝区域解剖分区，简便实用，可有效指导颞下窝区域手术，有临床推广运用价值。.