free flap

自由皮瓣
  • 文章类型: Journal Article
    目的:综合评价股前外侧皮瓣在下肢重建(LLR)手术中的临床疗效,并通过Meta分析探讨其应用价值。
    方法:在PubMed等英文数据库中检索了有关LLR股前外侧皮瓣功效的发表的文章,WebofScience,Embase,和Cochrane图书馆,从成立之初到2023年11月进行了搜索。搜索词包括“大腿前外侧皮瓣”,“下肢”,“自由肌肉”和“重建”。随后,对符合条件的研究进行了数据提取,采用RevMan5.3软件进行数据分析。
    结果:最终选择包括12项适当的研究,共包括577名患者。Meta分析显示,不同类型皮瓣患者的住院时间差异可忽略不计(均差(MD)=-0.10,95%置信区间(CI)=-0.400.20,P>0.05)。此外,并发症的发生率差异不大(Riskdifference,RD=-0.02,95%CI=-0.090.05,P>0.05)。二次手术的发生率也没有显着差异(RD=-0.04,95%CI=-0.11-0.04,P>0.05)。然而,接受股前外侧皮瓣移植的患者的供体部位发病率急剧下降(赔率比(OR)=0.22,95%CI=0.10-0.49,P<0.05)。
    结论:股前外侧皮瓣在LLR手术中的临床疗效与住院时间无明显差异。并发症发生率,或需要二次手术相比其他皮瓣。然而,在LLR中使用股前外侧皮瓣可显着降低供体部位的发病率。
    OBJECTIVE: To comprehensively assess the clinical efficacy of the anterolateral thigh flap in lower limb reconstruction (LLR) surgeries and explore its application value via a meta-analysis.
    METHODS: Published articles on the efficacy of anterolateral thigh flap in LLR were retrieved in English databases such as PubMed, Web of Science, Embase, and The Cochrane Library, which were searched from their inception to November 2023. The search terms included \"anterolateral thigh flaps\", \"lower extremity\", \"free muscle\" and \"reconstruction\". Subsequently, data extraction of eligible studies was carried out, and data analysis was conducted using RevMan 5.3 software.
    RESULTS: The final selection comprised 12 appropriate studies, encompassing a total of 577 patients. Meta-analysis demonstrated that negligible differences existed in the length of hospital stay among patients treated with different types of flaps (mean difference (MD) =-0.10, 95% confidence interval (CI) =-0.400.20, P>0.05). Additionally, the occurrence of complications differed slightly (Risk difference (RD) =-0.02, 95% CI=-0.090.05, P>0.05). The incidence of secondary surgeries also demonstrated non-significant differences (RD=-0.04, 95% CI=-0.11-0.04, P>0.05). Nevertheless, patients who underwent anterolateral thigh flap transplantation exhibited a drastic decrease in donor site morbidity (Odds ratio (OR) =0.22, 95% CI=0.10-0.49, P<0.05).
    CONCLUSIONS: The clinical efficacy of the anterolateral thigh flap in LLR surgeries shows no significant differences in hospital stay, complication rates, or the need for secondary surgeries compared to other flaps. However, using anterolateral thigh flap in LLR significantly reduces donor site morbidity.
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  • 文章类型: Journal Article
    背景:多个相邻缺陷(MAD)的有效重修需要精确的重建策略。各种方法(例如,已经报道了几个皮瓣转移或接受部位的预层压),但是接收者站点损伤,疼痛,长期住院,低成本效益的结果注定会把它们视为妥协的方法。本研究旨在评估使用游离的多桨浅旋支髂动脉穿支(SCIAP)皮瓣重建MADs的可行性。
    方法:从2015年12月至2020年12月,我们招募了使用各种多桨SCIAP皮瓣(2桨,3桨,和4桨)。收集各组患者的人口统计学和结果。
    结果:32,21名,6名患者接受了2桨,3桨,和4桨SCIAP襟翼转移,分别。所有多桨SCIAP皮瓣均存活,没有血管问题,捐赠地点直接关闭。除3例2桨SCIAP皮瓣经旋髂浅静脉回流引流外,大多数病例(n=56)由静脉顺流引流。轻微的并发症,包括部分皮瓣坏死(4例)和股外侧皮神经麻痹(11例),被保守地对待。所有患者对重建结果均满意。
    结论:多个相邻缺损重建仍然是一个难题,缺乏黄金标准。自由的多桨SCIAP皮瓣被证明是一种有希望的替代品,不仅丰富了其多功能性,而且还初步突出了“以需要取代需要”的重建需求。
    BACKGROUND: The efficient resurfacing of multiple adjacent defects (MADs) requires precise reconstructive strategy. Various approaches (e.g., several flap transferring or prelamination of the recipient site) have been reported, but recipient-site impairments, pain, long hospitalization, and low cost-benefit results fatefully considered them as compromise approaches. This study aims to evaluate the feasibility of MADs reconstruction with free multipaddle superficial circumflex iliac artery perforator (SCIAP) flaps.
    METHODS: From Dec 2015 to Dec 2020, we enrolled patients with upper and lower extremity defects treated with various multipaddle SCIAP flaps (2-paddle, 3-paddle, and 4-paddle). Patient demographics and outcomes of each group were collected.
    RESULTS: Thirty-two, 21, and 6 patients underwent 2-paddle, 3-paddle, and 4-paddle SCIAP flaps transfers, respectively. All multipaddle SCIAP flaps survived without vascular problems, and the donor sites were closed directly. Except for 3 cases of 2-paddle SCIAP flaps drained by superficial circumflex iliac vein venous return, most cases (n = 56) were drained by venae comitans. Minor complications, including partial flap necrosis (4 cases) and lateral femoral cutaneous nerve palsies (11 cases), were treated conservatively. All patients were satisfied with the reconstructive outcome.
    CONCLUSIONS: Multiple adjacent defects reconstruction is still a Gordian knot and lacks a golden standard. The free multipaddle SCIAP flap was demonstrated as a promising alternative, not only enriching its versatility but also initially highlighting the \"replace need with need\" reconstructive demand.
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  • 文章类型: Journal Article
    The quality of vessel anastomosis is a key element for the success of free flap reconstruction. When adopting free flaps for oral and maxillofacial defect reconstruction, skills in selecting vessels, determining the clinical manifestations of the recipient vessel, and anastomosis technique are needed. Key points on postoperative flap observation were also required. We are experienced on this subject given that we have accomplished more than 1 000 free flaps for patients with oral and maxillofacial defects in the last 5 years. In this article, we summarize the skills and key points in free flap reconstruction of oral and maxillofacial defects, including vessel anastomosis skills, vessel selection, and vessel crisis diagnosis.
    血管吻合的质量是决定游离皮瓣移植修复术是否成功最为关键的因素。游离皮瓣在修复口腔颌面部缺损的应用中存在血管选择、受区血管相关术中表现和血管吻合技术等方面的诸多特点及技巧。同时,术后对皮瓣危象、并发症进行判断和处理时也有较多的关键点。笔者的团队在近年来开展了大量的口腔颌面缺损游离皮瓣修复,在口腔颌面颈部的血管吻合方面积累了大量的经验。本文针对口腔颌面缺损游离皮瓣修复中动静脉吻合的技巧、血管选择、血管危象的判断及处理等问题进行评述。.
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  • 文章类型: Journal Article
    目的:本研究旨在探讨游离皮瓣重建后血管并发症的危险因素,并利用机器学习方法开发一种预测游离皮瓣重建患者血管并发症的临床辅助评估工具。
    方法:回顾性分析2019年1月1日至2021年12月31日遵义医学院附属医院行游离皮瓣重建患者的医疗资料。采用统计学分析筛选危险因素。使用合成少数过采样技术生成并增强了训练数据集。Logistic回归,随机森林和神经网络,模型被训练,使用此数据集。然后使用测试集评估和比较这三个预测模型的性能,有四个指标,接收器工作特性曲线下面积(AUC),准确度,灵敏度,和特异性。
    结果:本研究共纳入570例接受游离皮瓣重建的患者,其中46人发生术后血管并发症。在测试的模型中,神经网络模型在测试集上表现出优越的性能,AUC为0.828。多因素logistic回归分析确定术前血红蛋白水平,术前纤维蛋白原水平,操作持续时间,吸烟史,吻合的数量,和外周血管损伤是游离皮瓣重建后血管并发症的独立危险因素。神经网络中排名前五位的预测因素是纤维蛋白原含量,操作持续时间,捐赠网站,体重指数(BMI),和血小板计数。
    结论:血红蛋白水平,纤维蛋白原水平,操作持续时间,吸烟史,吻合静脉是游离皮瓣重建后血管并发症的独立危险因素。这些风险因素增强了机器学习模型预测血管并发症发生和识别高危患者的能力。神经网络模型优于逻辑回归和随机森林模型,提示其可能帮助临床医生早期识别高危患者,从而减轻患者痛苦并改善预后。
    OBJECTIVE: This study aims to explore the risk factors of vascular complications following free flap reconstruction and to develop a clinical auxiliary assessment tool for predicting vascular complications in patients undergoing free flap reconstruction leveraging machine learning methods.
    METHODS: We reviewed the medical data of patients who underwent free flap reconstruction at the Affiliated Hospital of Zunyi Medical University retrospectively from January 1, 2019, to December 31, 2021. Statistical analysis was used to screen risk factors. A training data set was generated and augmented using the synthetic minority oversampling technique. Logistic regression, random forest and neural network, models were trained, using this dataset. The performance of these three predictive models was then evaluated and compared using a test set, with four metrics, area under the receiver operating characteristic curve (AUC), accuracy, sensitivity, and specificity.
    RESULTS: A total of 570 patients who underwent free flap reconstruction were included in this study, 46 of whom developed postoperative vascular complications. Among the models tested, the neural network model exhibited superior performance on the test set, achieving an AUC of 0.828. Multivariate logistic regression analysis identified that preoperative hemoglobin levels, preoperative fibrinogen levels, operation duration, smoking history, the number of anastomoses, and peripheral vascular injury as statistically significant independent risk factors for vascular complications post-free flap reconstruction. The top five predictive factors in the neural network were fibrinogen content, operation duration, donor site, body mass index (BMI), and platelet count.
    CONCLUSIONS: Hemoglobin levels, fibrinogen levels, operation duration, smoking history, and anastomotic veins are independent risk factors for vascular complications following free flap reconstruction. These risk factors enhance the ability of machine learning models to predict the occurrence of vascular complications and identify high-risk patients. The neural network model outperformed the logistic regression and random forest models, suggesting its potential to aid clinicians in early identification of high-risk patients thereby mitigating patient suffering and improving prognosis.
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  • 文章类型: Journal Article
    目的:探讨骨间前动脉背支放射状骨皮支游离复合皮瓣移植重建手部骨缺损和皮肤缺损的临床应用及疗效。
    方法:解剖学,骨间前动脉背侧分支的radial骨皮分支具有恒定的侧支吻合,可以从前臂的背侧提供大的背皮瓣。该皮瓣用于5例皮肤和指骨缺损的重建。
    结果:所有5例重建均成功,结合方骨和良好的美容效果。所有的捐献者都可以直接关闭。
    结论:前臂背皮瓣重建是一种可靠的手术,创伤最小。因此,它是修复皮肤和指骨缺损的理想方法。
    OBJECTIVE: To explore the clinical application and efficacy of transplantation of free composite flaps supplied by radial osteocutaneous branch of the dorsal branch of the anterior interosseous artery for reconstructing bone and skin defects in the hand.
    METHODS: Anatomically, the radial osteocutaneous branch of the dorsal branch of the anterior interosseous artery has constant collateral anastomoses which can provide a large dorsoradial flap from the dorsum of the forearm. This flap was used for reconstruction in five cases of cutaneous and phalangeal defects.
    RESULTS: Reconstruction was successful in all five cases, with consolidated phalanx and good cosmetic results. All donor sites could be closed directly.
    CONCLUSIONS: Reconstruction with dorsoradial forearm flaps is a reliable procedure which causes minimal trauma. Thus, it is an ideal approach for repairing cutaneous and phalangeal defects.
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  • 文章类型: Journal Article
    背景:应用端侧(ETS)吻合术进行皮瓣转移带来了挑战,特别是在供体动脉和皮瓣动脉之间存在明显尺寸差异的情况下。在这里,一种新的ETS吻合技术,称为“吸盘样ETS吻合术”,旨在减轻和纠正此类船舶差异。本研究旨在通过游离皮瓣转移评估该技术在组织缺损重建中的功效。
    方法:收集并回顾性分析2018年9月至2023年3月期间78例患者的病历和随访资料,这些患者使用吸盘样ETS吻合术进行游离皮瓣转移,动脉尺寸差异明显。
    结果:78例游离皮瓣转移患者中,动脉大小差异的范围(皮瓣动脉与供体动脉)为1:1.6-1:4(平均:1:2.5)。用吸盘样ETS技术吻合后,75例皮瓣成活,不需要额外的手术干预,单阶段成功率为96.2%。3例术后静脉危象,2例静脉探查后存活,1例皮瓣坏死,需要二次皮肤移植。7例面临伤口愈合延迟,但在换药后最终实现完全愈合。住院期间未观察到动脉危象。平均随访13个月,存活的皮瓣表现出极好的活力,没有皮瓣坏死或色素沉积。总的来说,应用吸盘样ETS动脉吻合术进行皮瓣转移,手术总成功率高达98.7%(77/78)。
    结论:应用吸盘样ETS吻合术治疗游离皮瓣转移是非常有效的,特别是在受者和供者动脉之间具有显著大小差异的情况下。
    BACKGROUND: The application of end-to-side (ETS) anastomosis for flap transfer poses challenges, particularly in cases of significant size discrepancy between the donor and flap arteries. Herein, a novel ETS anastomosis technique, termed \"sucker-like ETS anastomosis\", is developed to mitigate and rectify such vessel discrepancies. This study aims to evaluate the efficacy of this technique in tissue defect reconstruction through free flap transfer.
    METHODS: Between September 2018 and March 2023, the medical records and follow-up data of 78 patients who underwent free flap transfer using sucker-like ETS anastomosis for significant artery size discrepancies were collected and retrospectively analyzed.
    RESULTS: Among the 78 cases that received free flap transfer, the range of artery size discrepancy (flap artery vs donor artery) was 1:1.6-1:4 (mean: 1:2.5). Following anastomosis with the sucker-like ETS technique, 75 cases achieved flap survival without requiring additional surgical intervention, yielding a one-stage success rate of 96.2%. Three cases experienced post-operative venous crises, with two cases surviving after vein exploration and one case undergoing flap necrosis, necessitating a secondary skin graft. Seven cases faced delayed wound healing but eventually achieved complete healing following dressing changes. No arterial crisis was observed during hospitalization. With an average follow-up of 13 months, the surviving flaps exhibited excellent vitality without flap necrosis or pigment deposition. Overall, the application of sucker-like ETS arterial anastomosis for flap transfer resulted in a high overall surgical success rate of 98.7% (77/78).
    CONCLUSIONS: The application of sucker-like ETS anastomosis for free flap transfer is highly effective, particularly in cases with significant size discrepancy between the recipient and donor arteries.
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  • 文章类型: Journal Article
    我们报告了在Wassel-FlattIV-D型拇指重复术中使用游离外侧大脚趾皮瓣覆盖皮肤缺损的应用和结果。这项回顾性研究包括2020年6月至2021年9月期间接受治疗的五名患者,以纠正角状畸形并修复继发性皮肤缺损。所有的皮瓣都活了下来。术后随访8~12个月,所有重建拇指外观满意。日本手外科学会评分系统的结果在一名患者中表现优异,三个病人好,一个病人好。对齐的结果,尺骨和径向稳定性,4例患者的运动范围和美学方面(ALURRA)评分系统良好,1例患者中等。证据级别:IV。
    We report the application and results of skin defect coverage using the free lateral great toe flap in revision surgery for residual postoperative deformities in Wassel-Flatt type IV-D thumb duplications. This retrospective study included five patients treated between June 2020 and September 2021 to correct angular deformity and repair the secondary skin defect. All the flaps survived. The patients were followed up for 8-12 months and all the reconstructed thumbs had a satisfactory appearance. The results of the Japanese Society for Surgery of the Hand scoring system were excellent in one patient, good in three patients and fair in one patient. The results of the Alignment, Ulnar and Radial stability, Range of motion and Aesthetical aspects (ALURRA) scoring system were good in four patients and moderate in one patient.Level of evidence: IV.
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  • 文章类型: Letter
    暂无摘要。
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  • 文章类型: Case Reports
    对于外科医生来说,在近端残端截肢时恢复四指损伤,节段性损伤以及软组织缺损和即将发生的室综合征仍然是挑战。在特殊情况下,考虑临时异位寄养作为实际选择的立即移植。我们描述了暂时的异位手指植入物,用于掌指骨(MCP水平)的挤压伤,手扭转以及前臂隔室被植入足背。扭转手指用微型外固定器临时固定,以稳定作为抢救,采用ALT游离皮瓣覆盖手部软组织缺损。使用长椎弓根到解剖部位进行了存活人物的再植术,而不会压碎MCP关节,以便以后将肌腱转移到手指。恢复了满意的功能,没有寄养部位(足部)并发症,如疼痛或残疾。作者验证了截肢者的异位寄养以及在特殊情况下选择的四肢救助程序。
    Retrieval of four finger injury at proximal stump amputation with segmental injury along with soft tissue defect and impending compartment syndrome continues to be challenge for the surgeon. Immediate transplant considering temporary ectopic foster as a practical option in special case. We describe temporary ectopic finger implant for crush injury at Metacarpophalangeal (MCP level) with hand torsion along with forearm compartment was fostered to Dorsum of the foot. The torsion fingers was temporary fixed with mini external fixator for stabilization as salvage, ALT free flap was used to cover soft tissue defect of the hand. Replantation of survived figure was performed using the long pedicle to anatomical site without crushing the MCP joint to allow for later tendon transfer for finger. Satisfactory function regained with no foster site (foot) complication like pain or disability. The author validated ectopic foster for amputee as and procedure of choice for salvage of extremity under special circumstances.
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  • 文章类型: Journal Article
    描述一种用直角螺丝刀对钛网进行内侧固定的新颖方法,用于眶底和上颌骨重建,并比较改良和传统方法对眶底重建的重建结果。
    回顾性分析2018年至2021年北京大学口腔医院23例采用个体化钛网进行上颌骨切除及眶底缺损重建的患者资料。8例患者接受钛网和斜角螺丝刀改良眶底重建术(A组),15例患者接受传统眶底重建术(B组)。计算A组和B组钛网与颊瓣的接触面积。钛网变形,记录骨折或暴露。评估术后眼功能和美学恢复的成功。
    平均随访15.7个月(范围,9-22个月)。A组改良钛网与颊瓣的接触面积(13.11±1.41cm2)明显小于B组传统钛网(21.83±1.23cm2;p<0.05)。B组中有2例患者出现钛网暴露。23例患者的面部对称性自我评估在A组(7.75±0.71)和B组(6.68±1.30;p>0.05)之间无显着性差异。没有具体的并发症报告。
    我们提出了一种新颖的方法,用直角螺丝刀对钛网进行zy骨内侧固定,用于眶底和上颌骨重建,有可能防止钛网术后暴露。
    III级(回顾性比较研究)。
    UNASSIGNED: To describe a novel method of medial fixation of titanium mesh with a right-angled screwdriver for orbital floor and maxillary reconstruction and to compare the reconstruction outcome of orbital floor reconstruction with modified and traditional methods.
    UNASSIGNED: The data of 23 patients who underwent maxillectomy and orbital floor defect reconstruction by individualized titanium mesh in Peking University School and Hospital of Stomatology between 2018 and 2021 were retrospectively reviewed. While eight patients received modified orbital floor reconstruction with titanium mesh and angled screwdriver (group A), 15 patients received traditional orbital floor reconstruction (group B). The contact area with buccal flap for titanium mesh in groups A and B was calculated. Titanium mesh deformation, fracture or exposure was recorded. Postoperative ophthalmic function and success of esthetic restoration were assessed.
    UNASSIGNED: Mean follow-up was for 15.7 months (range, 9-22 months). The contact area with buccal flap for the modified titanium mesh in group A (13.11 ± 1.41 cm2) was significantly less than that of the traditional titanium mesh in group B (21.83 ± 1.23 cm2; p < .05). The exposure of titanium mesh occurred in two patients in group B. The self-evaluation of facial symmetry for 23 patients showed no significant difference between group A (7.75 ± 0.71) and group B (6.68 ± 1.30; p > .05). No specific complications were reported.
    UNASSIGNED: We propose a novel method of zygomatic medial fixation of titanium mesh with a right-angled screwdriver for orbital floor and maxillary reconstruction, which has the potential to prevent the postoperative exposure of titanium mesh.
    UNASSIGNED: Level III (Retrospective comparative study).
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