■表征威尔逊病(WD)领域中引用最多的100篇文章,以提供一般概述并揭示经典研究的历史发展,和新发现。
■在WebofScience数据库上搜索了与WD相关的文章。检索到100篇引用最多的文章,并对其进行描述性统计分析。
■选择了WD领域引用最多的100篇文章,并选择了几个参数,包括引用计数,引文密度,第一作者,通讯作者,journal,国家,机构,并提取关键词以评估文章的整体质量和影响。
■选定的100篇文章中的大多数都是在1990年代和2000年代发表的,2005年发表的文章最多。每篇论文的引用次数从100到1631不等,平均引用次数为199.03。排名前100位的文章发表在38种期刊上,大部分发表在《生物化学杂志》上。最突出的研究主题是临床表现,临床试验,铜传输机制,和铜代谢失调。Prof.SvetlanaLutsenko,Prof.彼得·费伦西,Prof.乔治·J·布鲁尔,和教授。DianeW.Cox是该领域最有影响力的研究人员之一,而欧美国家在研究产出方面最占主导地位。关键词网络分析识别\"转运ATP酶,\"\"ATP7B,\"和\"Menkes疾病\"作为最有影响力的关键字。此外,疾病管理,WD临床表型,ATP7B功能,铜代谢是未来WD研究的潜在热点。
■这项研究揭示了WD研究领域最有影响力的文章。此外,介绍了全球WD领域的主要研究主题和技术创新。
UNASSIGNED: To characterize the 100 most-cited articles in the field of Wilson\'s Disease (WD) to provide a general overview and reveal the historical developments classical studies, and new findings.
UNASSIGNED: WD-related articles were searched on the Web of Science database. The 100 most-cited articles were retrieved and their descriptive statistics were analyzed.
UNASSIGNED: The 100 most-cited articles in the field of WD were selected and several parameters, including citation count, citation density, first author, corresponding author, journal, country, institution, and keywords were extracted to assess the overall quality and impact of the articles.
UNASSIGNED: Most of the selected 100 articles were published in the 1990s and 2000s, with the highest number of articles published in 2005. Citations per paper ranged from 100 to 1,631, with a mean number of citations of 199.03. The top 100 articles were published in 38 journals, and the majority were published in the Journal of Biological Chemistry. The most prominent research themes were clinical presentations, clinical trials, copper transport mechanisms, and dysregulation of copper metabolism. Prof. Svetlana Lutsenko, Prof. Peter Ferenci, Prof. George J. Brewer, and Prof. Diane W. Cox were among the most influential researchers in this field, while Euro-American countries were the most dominant in terms of research output. Keywords network analysis identified \"Transporting ATPase,\" \"ATP7B,\" and \"Menkes disease\" as the most influential keywords. Moreover, disease management, WD clinical phenotype, ATP7B function, and copper metabolism are potential hotspots in future WD research.
UNASSIGNED: This study reveals the most influential articles in the field of WD research. In addition, the major research themes and technological innovations in the field of WD worldwide are presented.