导电/绝缘油墨已经受到广泛关注,用于制造各种增材制造技术。然而,目前的油墨通常表现出较差的生物相容性,并且在生理条件下面临电导率和机械刚度之间的权衡。这里,提出了基于二维材料的导电/绝缘生物墨水。导电生物墨水,石墨烯(GR)-聚(乳酸-乙醇酸)(PLGA),通过将导电GR引入可降解的聚合物基质中来制备,PLGA,而绝缘的生物墨水,氮化硼(BN)-PLGA,通过添加绝缘BN合成。通过优化材料比,这项工作实现了对生物墨水的机电特性的精确控制,从而能够根据具体要求进行导电网络的柔性构造。此外,这些生物墨水与3D打印等各种制造技术兼容,静电纺丝,旋涂,和注塑成型,拓展其在生物医学领域的应用范围。总的来说,结果表明,这些导电/绝缘生物墨水提供了改进的机械,电子,和各种新兴生物医学应用的生物学特性。
Conducting/insulating inks have received significant attention for the fabrication of a wide range of additive manufacturing technology. However, current inks often demonstrate poor biocompatibility and face trade-offs between conductivity and mechanical stiffness under physiological conditions. Here, conductive/insulating bioinks based on two-dimensional materials are proposed. The conductive
bioink, graphene (GR)-poly(lactic-co-glycolic acid) (PLGA), is prepared by introducing conductive GR into a degradable polymer matrix, PLGA, while the insulating
bioink, boron nitride (BN)-PLGA, is synthesized by adding insulating BN. By optimizing the material ratios, this work achieves precise control of the electromechanical properties of the bioinks, thereby enabling the flexible construction of conductive networks according to specific requirements. Furthermore, these bioinks are compatible with a variety of manufacturing technologies such as 3D printing, electrospinning, spin coating, and injection molding, expanding their application range in the biomedical field. Overall, the results suggest that these conducting/insulating bioinks offer improved mechanical, electronic, and biological properties for various emerging biomedical applications.