目的:了解鄂西北某稀土矿区居民血液和头发中稀土元素的含量,并评估REs对当地居民健康状况的影响。
方法:共有191名来自RE矿区核心区的居民和186名来自非RE矿区的居民,20-69岁,被选中。采用电感耦合等离子体质谱法测定调查对象血液和头发中REs的含量,并与现有文献价值进行了比较。同时,将对居民的健康状况进行血液检查和问卷调查,以检查人类RE富集是否会导致地方病。
结果:矿区居民血液中REs的平均总含量为60.22ng/mL,是对照区的3.35倍;头发中REs的平均总含量为1197.91ng/g,是控制区的6.32倍。随着年龄的增长,矿区男性和女性血液和头发中的REs丰度增加。钇和钪在血液和头发中的比例远高于土壤中的比例。与头发相比,钇和钪更容易在血液中富集。发生脂肪肝的概率无显著差异,乙型肝炎,低血糖,低血压,高血压和心脏病以及RE矿区居民与控制区居民的平均寿命。
结论:居民每日平均REs摄入量高,导致人的血液和头发中REs积累相对较大,但是目前没有发现重大和实质性的人类健康损害。
OBJECTIVE: To investigate the content of rare earth elements(REs)in blood and hair of residents in a RE mining area in Northwest Hubei, and evaluate the impact of REs on the health status of local residents.
METHODS: A total of 191 residents from the core area of RE mining areas and 186 residents from non RE mining areas, aged 20-69, were selected. The content of REs in the blood and hair of the survey subjects was measured using inductively coupled plasma mass spectrometry, and compared with existing literature values. At the same time, blood tests and questionnaire surveys will be conducted on the health status of residents to examine whether human RE enrichment can lead to endemic diseases.
RESULTS: The average total content of REs in the blood of residents in the mining area was 60.22 ng/mL, which was 3.35 times that of the control area; The average total content of REs in hair was 1197.91 ng/g, which was 6.32 times higher than the control area. As age increasing, the abundance of REs in the blood and hair of both men and women in mining areas increased. The proportion of
Yttrium and Scandium in the blood and hair were much higher than that in the soil. Compared to hair,
Yttrium and Scandium were more easily enriched in the blood. There was no significant difference in the probability of fatty liver, hepatitis B, hypoglycemia, hypotension, hypertension and heart disease and the average life span between residents in RE mining areas and those in the control area.
CONCLUSIONS: The high daily average dietary intake of REs in residents leads to a relatively large accumulation of REs in human blood and hair, but no significant and substantial human health damage has been found at present.