目的:探讨儿童角度α和κ与屈光和生物学参数的相关性。
方法:本病例系列研究包括219名儿童的438只眼(男/女=105/114,年龄:3-15岁)。眼睛生物参数,包括轴向长度,角膜曲率半径(CR),白到白距离(WTW),角度κ和角度α,使用IOLMaster700测量;在睫状肌麻痹下评估自动屈光。根据CR将眼睛分为不同的组,WTW,和性别来比较角度α和κ,并分析了角度α和κ的生物学参数差异之间的相关性。
结果:轴向长度的平均值,CR,WTW,角度α,角度κ为23.24±1.14毫米,7.79±0.27mm,11.68±0.41mm,0.45±0.25mm,和0.27±0.22毫米,分别。角度α与CR和WTW相关(固定效应系数[FEC]=0.237,p=0.015;FEC=-0.109,p=0.003;分别),和角度κ也与CR和WTW相关(FEC=0.271,p=0.003;FEC=-0.147,p<0.001)。比较子组,大CR和小WTW组有较大的角度α(0.49±0.27vs.0.41±0.21,p<0.001;0.46±0.27vs.0.44±0.21,p<0.05)和κ(0.29±0.25vs.0.24±0.15,p<0.01;0.29±0.25vs.分别为0.26±0.19,p<0.05)。眼间角度α和κ的差异与眼间WTW相关(r=-0.255,p<0.001;r=-0.385,p<0.001)。具有较小WTW的眼睛倾向于具有较大的角度κ(0.28±0.27vs.0.25±0.15,p<0.05)。
结论:角度α/κ的大小可能与CR和WTW有关,和较大的WTW眼睛可能暗示与另一只眼睛相比更小的角度κ。
OBJECTIVE: To investigate the correlation of angles α and κ with the refractive and biological parameters in children.
METHODS: This case-series study included 438 eyes of 219 children (males/females = 105/114, age: 3-15 years). Ocular biometric parameters, including axial length, corneal radius of curvature (CR), white-to-white distance (WTW), angle κ and angle α, were measured using IOL Master 700; auto-refraction were assessed under cycloplegia. The eyes were assigned to different groups based on CR, WTW, and gender to compare the angles α and κ, and analyze the correlations between the differences of biological parameters on angles α and κ.
RESULTS: The means of axial length, CR, WTW, angle α, and angle κ were 23.24 ± 1.14 mm, 7.79 ± 0.27 mm, 11.68 ± 0.41 mm, 0.45 ± 0.25 mm, and 0.27 ± 0.22 mm, respectively. Angle α was correlated with CR and WTW (fixed effect coefficient [FEC] = 0.237, p = 0.015; FEC = -0.109, p = 0.003; respectively), and angle κ also correlated with CR and WTW (FEC = 0.271, p = 0.003; FEC = -0.147, p < 0.001, respectively). Comparing subgroups, the large CR and small WTW group had larger angles α (0.49 ± 0.27 vs. 0.41 ± 0.21, p < 0.001; 0.46 ± 0.27 vs. 0.44 ± 0.21, p < 0.05, respectively) and κ (0.29 ± 0.25 vs. 0.24 ± 0.15, p < 0.01; 0.29 ± 0.25 vs. 0.26 ± 0.19, p < 0.05, respectively). The differences in interocular angles α and κ showed correlation with interocular WTW (r = - 0.255, p < 0.001; r = - 0.385, p < 0.001). Eyes with smaller WTW tended to have larger angle κ (0.28 ± 0.27 vs. 0.25 ± 0.15, p < 0.05).
CONCLUSIONS: The size of angle α/κ may be correlated to CR and WTW, and a larger WTW eye may suggest a smaller angle κ compared with the fellow eye.