SUICIDE

自杀
  • 文章类型: Journal Article
    警告标志是自杀风险的近端指标,尽早认识到有效的预防策略。本研究旨在探讨基于安全规划框架的中国情绪障碍患者自我识别的自杀警告信号。
    研究人员与患者合作制定了安全计划,并根据该计划编制了警告标志。进行词频和网络分析以识别关键警告标志。定向内容分析将这些迹象分类为认知,情感,行为,或根据自杀模式理论的生理主题。此外,我们检查了具有不同人口统计学特征的参与者之间报告的警告信号的潜在差异,包括年龄,性别,和自杀未遂史.
    “情绪低落”和“哭泣”成为突出的警告信号,与“社会退出”紧随其后。患者通常在自杀危机期间报告情绪主题,经常同时经历两到三个主题,主要关注情感,行为,和生理主题。与女性相比,男性同时报告三个体征主题的比例更高(P<0.05),而在具有其他人口统计学特征的患者中,警告标志没有观察到差异。
    这项研究提供了对中国情绪障碍患者的警告信号的细致理解。调查结果强调了全面自杀风险管理策略的必要性,强调针对情绪调节和社会支持的干预措施。这些见解为加强自杀预防和干预工作提供了有价值的信息。
    UNASSIGNED: Warning signs serve as proximal indicators of suicide risk, making early recognition imperative for effective prevention strategies. This study aimed to explore self-identified suicide warning signs among Chinese patients with mood disorders based on safety planning framework.
    UNASSIGNED: Researchers collaborated with patients to develop a safety plan and compiled warning signs based on it. Word frequency and network analysis were conducted to identify key warning signs. Directed content analysis categorized these signs into cognitive, emotional, behavioral, or physiological themes according to the suicide mode theory. Additionally, we examined potential variations in reported warning signs among participants with different demographic characteristics, including age, gender, and history of suicide attempts.
    UNASSIGNED: \"Low mood\" and \"crying\" emerged as prominent warning signs, with \"social withdrawal\" closely following. Patients commonly reported emotional themes during suicidal crises, often experiencing two to three themes simultaneously, primarily focusing on emotional, behavioral, and physiological themes. Males exhibited a higher proportion of concurrently reporting three sign themes compared to females (P < 0.05), while no difference was observed in warning signs among patients with other demographic traits.
    UNASSIGNED: This study offers a nuanced understanding of warning signs among mood disorder patients in China. The findings underscore the necessity for comprehensive suicide risk management strategies, emphasizing interventions targeting emotional regulation and social support. These insights provide valuable information for enhancing suicide prevention and intervention efforts.
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  • 文章类型: Journal Article
    在丧亲之后,我们的研究探索了长期悲伤障碍(PGD)的微妙之处,特别关注其与自杀行为的相关性及其跨性别的差异。这项研究旨在阐明性别对患有PGD的个体中这些行为的影响,从而增强我们的理解并促进量身定制的治疗干预措施的发展。
    到11月24日,2023年,我们严格审查了关键数据库,如PubMed、WebofScience,科克伦图书馆,PsycINFO,和Embase。独立地,两名研究人员对参与者进行了详细的访谈并填写了问卷,以收集人口统计信息并记录长期悲伤障碍的情况.该研究还精心追踪了自杀意念的发生,自杀未遂,自杀死亡,以及参与者的自我伤害。
    研究结果表明,22.34%的男性报告有自杀意念(95%CI:21.33-23.35),这一数字在女性中上升到26.84%(95%CI:25.99-27.69)。值得注意的是,12.11%的男性自杀未遂(95%CI:11.49-12.72),略高于女性的9.60%(95%CI:9.17-10.04)。在自杀死亡中观察到更显著的差异,男性的比率为3.66%(95%CI:3.32-4.00),而女性的比率为7.12%(95%CI:6.44-7.81)。此外,男性自伤发生率较低,2.48%(95%CI:2.03-2.94),比女性,报告率为5.09%(95%CI:4.69-5.49)。这些模式突出表明,迫切需要采取针对性别的干预措施,以减少这些重大差距。
    这项研究清楚地强调了性别对长期悲伤障碍患者自杀行为表现的深远影响。它揭示了女性更容易有自杀意念,自我伤害,自杀死亡,而男性主要表现出更高的自杀企图和冒险行为的发生率。这些未介导的趋势凸显了针对特定行为的针对性别的临床干预措施的必要性,并修改了通常抵制传统方法的流行模式。
    PROSPERO(约克。AC.英国),标识符CRD42023480035。
    UNASSIGNED: In the aftermath of bereavement, our research explores the subtleties of Prolonged Grief Disorder (PGD), focusing particularly on its correlation with suicidal behaviors and their variation across genders. This study seeks to elucidate the impact of gender on these behaviors among individuals suffering from PGD, thereby enhancing our understanding and facilitating the development of tailored therapeutic interventions.
    UNASSIGNED: By November 24th, 2023, we had rigorously reviewed key databases such as PubMed, Web of Science, Cochrane Library, PsycINFO, and Embase. Independently, two researchers conducted detailed interviews and filled out questionnaires with participants to gather demographic information and record instances of prolonged grief disorder. The study also meticulously tracked occurrences of suicidal ideation, suicide attempts, suicide deaths, and self-injury among the participants.
    UNASSIGNED: The findings indicate that 22.34% of males reported suicidal ideation (95% CI: 21.33-23.35), a figure that rises to 26.84% among females (95% CI: 25.99-27.69). Notably, 12.11% of males attempted suicide (95% CI: 11.49-12.72), marginally surpassing the 9.60% observed in females (95% CI: 9.17-10.04). More striking disparities were observed in suicide deaths, with rates for males at 3.66% (95% CI: 3.32-4.00) compared to a notably higher 7.12% for females (95% CI: 6.44-7.81). Furthermore, the incidence of self-injury was lower among males, at 2.48% (95% CI: 2.03-2.94), than in females, who reported a rate of 5.09% (95% CI: 4.69-5.49). These patterns underscore the critical need for gender-specific interventions aimed at reducing these significant disparities.
    UNASSIGNED: This study distinctly underscores the profound impact of gender on the manifestation of suicidal behaviors in individuals afflicted with prolonged grief disorder. It reveals that females are more prone to suicidal ideation, self-injury, and suicide deaths, while males predominantly exhibit a higher incidence of suicide attempts and risk-taking behaviors. These unmediated trends highlight the necessity for gender-specific clinical interventions tailored to address particular behaviors and modify prevalent patterns that typically resist conventional approaches.
    UNASSIGNED: PROSPERO (york.ac.uk), identifier CRD42023480035.
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  • 文章类型: Journal Article
    中国年轻人(12-24岁)的自杀念头和行为(STBs)正在增加。尽管生态瞬时评估(EMA)已越来越多地用于研究全球STB,在中国,尚未对患有情绪障碍(MD)的年轻人进行研究。这项混合方法研究旨在评估75名患有MD的年轻人的自杀风险监测的可行性和可接受性。参与者完成了五到八次每日EMA调查,并为EMA研究佩戴了智能表带。半结构化访谈用于收集反馈。对EMA调查(73.0%)和智能频段(87.4%)的高依从性表明了可行性。参与者报告了EMA研究的总体积极经验(有帮助,友好,并且可以接受)。此外,他们愿意遵守EMA研究的原因是:(1)看到了恢复正常的可能性,\"和(2)经历返回的过程。然而,一小部分参与者有负面经历(例如,烦恼和缺少提示)。这项混合方法研究的结果为使用EMA(组合智能手机和可穿戴传感器设备)评估中国文化和社会背景下患有MD的年轻人的自杀行为的可行性和可接受性提供了初步支持。
    Suicidal thoughts and behaviors (STBs) are increasing among young people (aged 12-24 years) in China. Although Ecological Momentary Assessment (EMA) has been increasingly used to study STBs worldwide, no study has been conducted on young people with mood disorders (MD) in China. This mixed-method study aimed to evaluate the feasibility and acceptability of suicide risk monitoring in 75 young people with MD. Participants completed five to eight daily EMA surveys and wore smart bands for the EMA study. Semi-structured interviews were used to collect feedback. High adherence to EMA surveys (73.0 %) and smart bands (87.4 %) indicated feasibility. Participants reported an overall positive experience with the EMA study (helpful, friendly, and acceptable). Additionally, the reasons they were willing to comply with the EMA study were: (1) seeing the possibility of returning to \"normal,\" and (2) experiencing the process of returning. However, a small proportion of participants had negative experiences (e.g., annoyance and missing prompts). The results of this mixed-methods study provide preliminary support for the feasibility and acceptability of using EMA (combined smartphones and wearable sensor devices) to assess suicidality among young people with MD in the Chinese cultural and social context.
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  • 文章类型: Systematic Review
    背景:自我伤害和自杀的患病率高于艾滋病毒/艾滋病感染者(PLWHA)的普通人群。然而,现有研究报告的结果在中国差异很大。本系统评价和荟萃分析的目的是综合现有的高质量证据,以探讨中国PLWHA人群中自我伤害和自杀的患病率和影响因素。
    方法:我们通过PubMed、Embase,WebofScience,科克伦图书馆,SinoMed,CNKI,万方数据库,和CQVIP从成立到2022年9月1日。采用Sata16.0软件进行分析。
    结果:共纳入28项研究,样本量为1,433,971,质量评分令人满意,≥5。中国PLWHA的自杀意念(SI)患病率为30%,5%的自杀未遂(SA),8%为自杀计划(SP),7%为自杀未遂(AS),完成自杀为3‰。高柱头(OR=2.94,95CI:1.90-4.57),抑郁症(或,3.17;95CI,2.20-4.57),焦虑(或,3.06;95CI,2.23-4.20),低自尊(或,3.82、95CI、2.22-6.57),高艾滋病毒相关压力(OR,2.53;95CI,1.36-4.72),和失业(OR,2.50;95CI,1.51-4.15)是SI的危险因素;高社会支持(OR,0.61;95CI,0.44-0.84)和配偶感染艾滋病毒(OR,0.39;95CI,0.21-0.74)是SI的保护因素;抑郁(OR,1.62;95CI,1.24-2.13),高侵略性(或,4.66;95CI,2.59-8.39),和更多的负面生活事件(或,2.51;95CI,1.47-4.29)是AS的危险因素;教育水平高(OR,1.31;95CI,1.21-1.43)是CS的危险因素。
    结论:数字表明,大约三分之一的PLWHA有自杀意念,在中国,千分之三的人完成了自杀。阳性事件是PLWHA患者自我伤害和自杀的保护因素,而负面事件是危险因素。这表明应将社会心理支持和风险评估纳入PLWHA的护理中。
    BACKGROUND: The prevalence of self-injury and suicide is higher than the general population of people living with HIV/AIDS (PLWHA). However, the results reported in existing studies are highly variable in China. The purpose of this systematic review and meta-analysis was to synthesize the currently available high-quality evidence to explore the prevalence and influence factors of self-injury and suicide among PLWHA in China.
    METHODS: We retrieve literature written in Chinese and English through databases such as PubMed, Embase, Web of Science, Cochrane Library, SinoMed, CNKI, WanFang Database, and CQVIP from inception to 1 September 2022. Sata 16.0 software was used for analysis.
    RESULTS: A total of 28 studies were included with a sample size of 1,433,971 and had a satisfactory quality score of ≥ 5. The prevalence among PLWHA in China were 30% for suicidal ideation (SI), 5% for suicide attempt (SA), 8% for suicide plan (SP), 7% for attempted suicide (AS), and 3‰ for completed suicide. High stigma (OR = 2.94, 95%CI: 1.90 - 4.57), depression (OR, 3.17; 95%CI, 2.20 - 4.57), anxiety (OR, 3.06; 95%CI, 2.23 - 4.20), low self-esteem (OR, 3.82, 95%CI, 2.22 - 6.57), high HIV related stress (OR, 2.53; 95%CI, 1.36 - 4.72), and unemployment (OR, 2.50; 95%CI, 1.51 - 4.15) are risk factors for SI; high social support (OR, 0.61; 95%CI, 0.44 - 0.84) and spouse infected with HIV (OR, 0.39; 95%CI, 0.21 - 0.74) are protective factors for SI; depression (OR, 1.62; 95%CI, 1.24 - 2.13), high aggression (OR, 4.66; 95%CI, 2.59 - 8.39), and more negative life events (OR, 2.51; 95%CI, 1.47 - 4.29) are risk factors for AS; high level of education (OR, 1.31; 95%CI, 1.21 - 1.43) is risk factor for CS.
    CONCLUSIONS: Figures indicate that approximately one-third of PLWHA had suicidal ideation, and three out of 1,000 completed suicide in China. Positive events are protective factors for self-injury and suicide among PLWHA, while negative events are risk factors. This suggests that psychosocial support and risk assessment should be integrated into the care of PLWHA.
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  • 文章类型: Journal Article
    自杀是全球严重的公共卫生问题。准确识别高危肺癌患者的自杀行为并及时采取干预措施已成为当前研究的热点。本研究旨在构建动态预测模型,以识别肺癌患者的自杀风险。患者来自监测,流行病学,和最终结果数据库,而气象数据是从疾病控制和预防中心获得的。该队列包括1979年1月至2011年12月的455,708名合格的肺癌患者。采用基于界标法的Cox比例风险回归模型,探讨气象因素和临床特征对肺癌患者自杀的影响。并建立这些患者自杀风险的动态预测模型。此外,亚组分析按年龄和性别进行.使用C指数评估模型的性能,Brier得分,曲线下面积(AUC)和校准图。在学习期间,肺癌患者中有666人死于自杀。动态预测模型的多变量Cox结果表明,年龄,婚姻状况,种族,性别,主站点,舞台,每月平均每日阳光,月平均气温是自杀的重要预测因素。动态预测模型表现出良好的一致性和辨别能力。亚组分析显示,在女性和年轻肺癌患者中,每月平均每日日照和每月平均温度与自杀的关联仍然显着。动态预测模型可以有效地结合时变协变量来预测肺癌患者的自杀死亡。这项研究的结果对评估肺癌个体的自杀风险具有重要意义。
    Suicide is a severe public health issue globally. Accurately identifying high-risk lung cancer patients for suicidal behavior and taking timely intervention measures has become a focus of current research. This study intended to construct dynamic prediction models for identifying suicide risk among lung cancer patients. Patients were sourced from the Surveillance, Epidemiology, and End Results database, while meteorological data was acquired from the Centers for Disease Control and Prevention. This cohort comprised 455, 708 eligible lung cancer patients from January 1979 to December 2011. A Cox proportional hazard regression model based on landmarking approach was employed to explore the impact of meteorological factors and clinical characteristics on suicide among lung cancer patients, and to build dynamic prediction models for the suicide risk of these patients. Additionally, subgroup analyses were conducted by age and sex. The model\'s performance was evaluated using the C-index, Brier score, area under curve (AUC) and calibration plot. During the study period, there were 666 deaths by suicide among lung cancer patients. Multivariable Cox results from the dynamic prediction model indicated that age, marital status, race, sex, primary site, stage, monthly average daily sunlight, and monthly average temperature were significant predictors of suicide. The dynamic prediction model demonstrated well consistency and discrimination capabilities. Subgroup analyses revealed that the association of monthly average daily sunlight and monthly average temperature with suicide remained significant among female and younger lung cancer patients. The dynamic prediction model can effectively incorporate covariates with time-varying to predict lung cancer patients\' suicide death. The results of this study have significant implications for assessing lung cancer individuals\' suicide risk.
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  • 文章类型: Journal Article
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  • 文章类型: Letter
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  • 文章类型: Journal Article
    背景:在COVID-19大流行期间,自杀已成为一个关键的公共卫生问题。有了社交距离措施,社交媒体已成为个人表达自杀想法和行为的重要平台。然而,现有的使用社交媒体数据的自杀研究通常忽略了用户之间的多样性和自杀风险的时间动态。
    目标:通过检查在COVID-19大流行期间r/SuicideWatchsubreddit上用户的发布量轨迹变化,这项研究旨在调查自杀风险变化的异质性模式,以帮助识别具有高自杀风险的社交媒体用户。我们还在大流行之前和期间描述了他们的语言特征。
    方法:我们从2019年3月至2022年8月每6个月为r/SuicideWatchsubreddit上的用户收集和分析帖子数据(N=6163)。然后使用基于增长的轨迹模型来研究后容量的轨迹,以识别大流行期间自杀风险的变化模式。还绘制并比较了帖子中语言特征的趋势,使用回归分析在轨迹组中识别语言标记。
    结果:我们在r/SuicideWatchsubreddit用户中确定了两个不同的发布量轨迹。一小部分用户(744/6163,12.07%)被标记为具有高自杀风险,在大流行期间,员额数量急剧而持久地增加。相比之下,大多数使用者(5419/6163,87.93%)被归类为低自杀风险,大流行期间员额数量持续低且温和增加。就大多数语言特征的频率而言,两组在大流行的初始阶段都显示出增加。随后,在高风险人群中,上升趋势继续下降,而低危组显示立即下降。大流行爆发一年后,两组在使用与人称代词类别相关的单词方面表现出差异;情感,社会,认知,和生物过程;驱动器;相对性;时间取向;和个人关注。特别是,高风险组在使用与愤怒相关的词语时是有区别的(比值比[OR]3.23,P<.001),悲伤(OR3.23,P<.001),健康(OR2.56,P=0.005),成就(OR1.67,P=.049),运动(OR4.17,P<.001),未来焦点(OR2.86,P<.001),和死亡(OR4.35,P<.001)在这个阶段。
    结论:根据大流行期间确定的2个后容量轨迹,这项研究将r/SuicideWatchsubreddit上的用户分为自杀高风险和低风险人群。我们的发现表明,应对大流行的自杀风险变化的异质性模式。高危人群也表现出明显的语言特征。我们建议在未来的公共卫生危机期间使用社交媒体数据对自杀风险进行实时监测,以便为潜在自杀风险高的个人提供及时的支持。
    BACKGROUND: Suicide has emerged as a critical public health concern during the COVID-19 pandemic. With social distancing measures in place, social media has become a significant platform for individuals expressing suicidal thoughts and behaviors. However, existing studies on suicide using social media data often overlook the diversity among users and the temporal dynamics of suicide risk.
    OBJECTIVE: By examining the variations in post volume trajectories among users on the r/SuicideWatch subreddit during the COVID-19 pandemic, this study aims to investigate the heterogeneous patterns of change in suicide risk to help identify social media users at high risk of suicide. We also characterized their linguistic features before and during the pandemic.
    METHODS: We collected and analyzed post data every 6 months from March 2019 to August 2022 for users on the r/SuicideWatch subreddit (N=6163). A growth-based trajectory model was then used to investigate the trajectories of post volume to identify patterns of change in suicide risk during the pandemic. Trends in linguistic features within posts were also charted and compared, and linguistic markers were identified across the trajectory groups using regression analysis.
    RESULTS: We identified 2 distinct trajectories of post volume among r/SuicideWatch subreddit users. A small proportion of users (744/6163, 12.07%) was labeled as having a high risk of suicide, showing a sharp and lasting increase in post volume during the pandemic. By contrast, most users (5419/6163, 87.93%) were categorized as being at low risk of suicide, with a consistently low and mild increase in post volume during the pandemic. In terms of the frequency of most linguistic features, both groups showed increases at the initial stage of the pandemic. Subsequently, the rising trend continued in the high-risk group before declining, while the low-risk group showed an immediate decrease. One year after the pandemic outbreak, the 2 groups exhibited differences in their use of words related to the categories of personal pronouns; affective, social, cognitive, and biological processes; drives; relativity; time orientations; and personal concerns. In particular, the high-risk group was discriminant in using words related to anger (odds ratio [OR] 3.23, P<.001), sadness (OR 3.23, P<.001), health (OR 2.56, P=.005), achievement (OR 1.67, P=.049), motion (OR 4.17, P<.001), future focus (OR 2.86, P<.001), and death (OR 4.35, P<.001) during this stage.
    CONCLUSIONS: Based on the 2 identified trajectories of post volume during the pandemic, this study divided users on the r/SuicideWatch subreddit into suicide high- and low-risk groups. Our findings indicated heterogeneous patterns of change in suicide risk in response to the pandemic. The high-risk group also demonstrated distinct linguistic features. We recommend conducting real-time surveillance of suicide risk using social media data during future public health crises to provide timely support to individuals at potentially high risk of suicide.
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  • 文章类型: Journal Article
    缺乏早期干预服务(EISs)与25岁以上的首发精神分裂症(FES)患者的自我伤害和自杀相关的证据。
    研究实施EIS计划前后FES患者的自我伤害和自杀率的变化。
    这项基于人群的队列研究在2001年1月1日至2020年3月31日期间对37,040名年龄在15至64岁的FES患者进行,使用了香港临床数据分析和报告系统的电子病历。从首次诊断为精神分裂症(指标日期)到死亡或研究期结束(2021年3月31日),对所有患者进行了随访。以先到者为准。统计分析于2023年7月至11月进行。
    EIS将早期精神病患者的早期评估服务(EASY)计划从15至25岁的患者扩展到15至64岁的患者(EASYPlus)。曝光是2011年4月EASYPlus计划的实施。对于1年时滞分析,暴露期定义为2012年4月至2021年3月。
    结果是实施EASYPlus计划前后FES患者的月自残率和自杀率。主分析采用中断时间序列分析。
    这项研究包括37,040例FES患者(发病时的平均[SD]年龄,39[12]岁;82.6%年龄大于25岁;53.0%女性患者)。1年时滞分析发现,在26至44岁的患者中,自我伤害率立即下降(比率[RR],0.77[95%CI,0.59-1.00])和45至64年(RR,0.70[95%CI,0.49-1.00])和男性患者(RR,0.71[95%CI,0.56-0.91])。发现所有FES患者的自我伤害率长期显着下降(15-25岁的患者:RR,0.98[95%CI,0.97-1.00];26-44岁的患者:RR,0.98[95%CI,0.97-0.99];45-64岁患者:RR,0.97[95%CI,0.96-0.98])。在15至25岁的患者中实施EASYPlus计划后,自杀率立即下降(RR,0.33[95%CI,0.14-0.77])和26至44年(RR,0.38[95%CI,0.20-0.73])。与反事实情景相比,EASYPlus计划可能使26~44岁患者的自残事件减少了6302次.
    这项EASYPlus计划的队列研究表明,延长的EIS与所有FES患者的自我伤害和自杀率降低有关,包括25岁以上的人。这些发现强调了为所有年龄段的患者开发量身定制的干预措施的重要性,以最大限度地提高EISs的益处。
    UNASSIGNED: Evidence on the association of early intervention services (EISs) with self-harm and suicide among patients with first-episode schizophrenia (FES) at older than 25 years is lacking.
    UNASSIGNED: To examine changes in self-harm and suicide rates among patients with FES before and after the implementation of an EIS program.
    UNASSIGNED: This population-based cohort study conducted among 37 040 patients aged 15 to 64 years with FES between January 1, 2001, and March 31, 2020, used electronic medical records from the Hong Kong Clinical Data Analysis and Reporting System. All patients were followed up from the first diagnosis of schizophrenia (the index date) until the date of their death or the end of the study period (March 31, 2021), whichever came first. Statistical analysis was performed from July to November 2023.
    UNASSIGNED: The EIS extended the Early Assessment Service for Young People With Early Psychosis (EASY) program from patients aged 15 to 25 years to those aged 15 to 64 years (EASY Plus). The exposure was the implementation of the EASY Plus program in April 2011. The exposure period was defined as between April 2012 and March 2021 for the 1-year-time-lag analysis.
    UNASSIGNED: The outcomes were monthly rates of self-harm and suicide among patients with FES before and after the implementation of the EASY Plus program. Interrupted time series analysis was used for the main analysis.
    UNASSIGNED: This study included 37 040 patients with FES (mean [SD] age at onset, 39 [12] years; 82.6% older than 25 years; 53.0% female patients). The 1-year-time-lag analysis found an immediate decrease in self-harm rates among patients aged 26 to 44 years (rate ratio [RR], 0.77 [95% CI, 0.59-1.00]) and 45 to 64 years (RR, 0.70 [95% CI, 0.49-1.00]) and among male patients (RR, 0.71 [95% CI, 0.56-0.91]). A significant long-term decrease in self-harm rates was found for all patients with FES (patients aged 15-25 years: RR, 0.98 [95% CI, 0.97-1.00]; patients aged 26-44 years: RR, 0.98 [95% CI, 0.97-0.99]; patients aged 45-64 years: RR, 0.97 [95% CI, 0.96-0.98]). Suicide rates decreased immediately after the implementation of the EASY Plus program among patients aged 15 to 25 years (RR, 0.33 [95% CI, 0.14-0.77]) and 26 to 44 years (RR, 0.38 [95% CI, 0.20-0.73]). Compared with the counterfactual scenario, the EASY Plus program might have led to 6302 fewer self-harm episodes among patients aged 26 to 44 years.
    UNASSIGNED: This cohort study of the EASY Plus program suggests that the extended EIS was associated with reduced self-harm and suicide rates among all patients with FES, including those older than 25 years. These findings emphasize the importance of developing tailored interventions for patients across all age ranges to maximize the benefits of EISs.
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