未经证实:阻塞性睡眠呼吸暂停(OSA)的特征是间歇性低氧血症和睡眠破碎。虽然在快速眼动(REM)睡眠期间呼吸暂停明显伴有严重的去饱和,REM相关OSA是OSA的独特表型,其主要与REM睡眠期间的呼吸紊乱相关。在这项研究中,我们调查了台湾REM相关OSA的临床特征.
UNASSIGNED:对2015年至2017年在台北荣民总医院诊断为OSA的所有患者进行回顾性分析,并分为REM相关OSA(REM-OSA)组。非REM相关OSA(NREM-OSA)组,和非分期特异性OSA组。临床人口统计学,OSA相关症状,多导睡眠图结果,并对三组患者的合并症进行分析。
未经证实:在1331名OSA患者中,414(31.1%)被归类为REM-OSA,808(60.7%)作为NREM-OSA,109(8.2%)为非阶段性特异性OSA。在针对OSA严重性进行调整之后,REM-OSA组的男性比例较低,更长的去饱和持续时间,在轻度和中度OSA中,与NREM-OSA组相比,最低点氧饱和度(SpO2)较低。在中度OSA中,与其他组相比,非分期特异性OSA组的OSA严重程度和去饱和程度更高.Epworth嗜睡量表评分和合并症的患病率在REM-OSA之间没有变化,NREM-OSA,和非阶段特异性OSA组。高REM-AHI/NREM-AHI比率与年轻有关,女性性别,高BMI,低AHI。
UASSIGNED:高REM-AHI/NREM-AHI比率的OSA患者与年轻年龄有关,女性性别,高BMI,低AHI。经OSA严重程度调整后,REM相关OSA患者的去饱和持续时间较长,最低点SpO2较低。
UNASSIGNED: Obstructive sleep apnea (OSA) is characterized by intermittent hypoxemia and sleep fragmentation. While apnea is pronounced with severe desaturation during rapid eye movement (
REM) sleep,
REM-related OSA is a distinct phenotype of OSA associated with respiratory disturbances predominantly during
REM sleep. In this study, we investigated the clinical features of
REM-related OSA in Taiwan.
UNASSIGNED: All patients diagnosed with OSA in the Taipei Veterans General Hospital from 2015 to 2017 were analyzed retrospectively and classified into REM-related OSA (
REM-OSA) group, non-
REM related OSA (NREM-OSA) group, and non-stage specific-OSA group. The clinical demographics, OSA-related symptoms, polysomnography results, and medical comorbidities of the three groups were analyzed.
UNASSIGNED: Among 1331 patients with OSA, 414 (31.1%) were classified as REM-OSA, 808 (60.7%) as NREM-OSA, and 109 (8.2%) as non-stage specific-OSA. After being adjusted for OSA severity, the REM-OSA group was associated with less portion of males, longer desaturation duration, and lower nadir oxygen saturation (SpO2) compared with the NREM-OSA group in mild and moderate OSA. In moderate OSA, the non-stage specific-OSA group featured more OSA severity and more desaturation compared with the other groups. The Epworth Sleepiness Scale scores and the prevalence of comorbidities did not vary among the REM-OSA, NREM-OSA, and non-stage specific-OSA groups. High
REM-AHI/NREM-AHI ratio was associated with young age, female gender, high BMI, and low AHI.
UNASSIGNED: OSA patients with high REM-AHI/NREM-AHI ratio are related to young age, female gender, high BMI, and low AHI. Patients with REM-related OSA presented with longer desaturation duration and lower nadir SpO2 after being adjusted for OSA severity.