目的:以前的研究集中在适当的修复治疗的好处,虽然很少有研究调查与口腔修复相关的健康风险。作为一个可修改的口腔健康指标,假体不合适(IFP)与高血压的相关性尚未得到充分研究.
方法:这项横断面研究涉及北京的158,659名成年人(2009-2017年),他们接受了口腔检查和血压测量。应用Logistic回归模型评估IFP与高血压患病率的相关性。收缩压(SBP)≥140mmHg,舒张压(DBP)≥90mmHg,以及不同固定IFP亚组(根据涉及的牙齿数量)和可移除IFP亚组的亚组分析。我们进一步研究了分层群体之间的效应变化。
结果:158,659人被纳入分析,IFP组346例(26.86%),非IFP组27,380例(17.40%)(p<0.001)为高血压。性别调整后,年龄,肥胖,血脂异常,糖尿病,hsCRP,心血管疾病家族史,自我报告吸烟,自我报告饮酒和WC,高血压的OR,SBP≥140mmHg,DBP≥90mmHg为1.330(95%CI:1.162-1.522),1.277(95%CI:1.098-1.486)和1.376(95%CI:1.186-1.596),分别为(p<0.05)。此外,经过充分调整,在有和无IFP的人群中,受累牙齿数量呈显著增加趋势,高血压风险呈显著增加趋势(p<0.001).IFP与血压的相关性在女性中更为明显,18-60岁,非肥胖和糖尿病参与者。
结论:作为一种可修改的口腔指标,IFP与高血压的高风险显著相关。
OBJECTIVE: Previous studies focused on the benefits of adequate prosthodontic treatment, while few studies have investigated the prosthodontic-related risks to health. As a modifiable oral health indicator, the association of ill-fitting prosthesis (IFP) with hypertension has not been fully explored.
METHODS: This cross-sectional study involved 158,659 adults in Beijing (2009-2017) receiving intra-oral examinations and blood pressure measurements. Logistic regression models were applied to assess the association of IFP with the prevalence of hypertension, systolic blood pressure (SBP) ≧ 140 mmHg and diastolic blood pressure (DBP) ≧ 90 mmHg, as well as subgroup analyses by different fixed IFP subgroups (according to involved teeth number) and removable IFP subgroup. We further investigated effect modifications among stratified populations.
RESULTS: 158,659 individuals were included for analysis, 346 (26.86%) in IFP group and 27,380 (17.40%) in non-IFP group (p < 0.001) were hypertensive. After adjustment of sex, age, obesity, dyslipidaemia, diabetes, hsCRP, family history of CVD, self-reported smoking, self-reported drinking and WC, ORs of hypertension, SBP ≧ 140 mmHg and DBP ≧ 90 mmHg were 1.330 (95% CI: 1.162-1.522), 1.277 (95% CI: 1.098-1.486) and 1.376 (95% CI: 1.186-1.596), respectively (p < 0.05). Furthermore, after full adjustment, the number of involved teeth showed a significant incremental trend with hypertension risk in the population with and without IFP (p for trend <0.001). The IFP-blood pressure associations were more pronounced in females, 18-60 years, non-obese and diabetic participants.
CONCLUSIONS: As a modifiable oral indicator, IFP was significantly associated with a higher risk of hypertension.