■许多研究已经调查了在俯卧位脊柱手术中PCV与VCV模式的效力和安全性的比较。然而,关于哪种通气模式的最大益处仍然存在争议。这项荟萃分析的主要目的是研究在PCV和VCV两种通气模式下,俯卧位脊柱手术的手术患者哪一种是最佳通气。
■我们对PubMed进行了全面搜索,Embase,WebofScience,Cochrane图书馆,和谷歌学者可能符合条件的文章。使用平均差异和相关的95%置信区间分析连续结果。采用ReviewManager5.4软件进行Meta分析。
■我们的荟萃分析包括8个RCT,涉及2012年至2020年间的454名患者。结果表明,IOB,在俯卧位脊柱手术中,VCV的Ppeak和CVP明显优于PCV。PCV的Cdyn和PaO2/FiO2比VCV高。但PCV和VCV在POB方面没有显著差异,Hb,HCT,HR和MAP
■PCV模式显示出比VCV模式更令人满意的效果。与相同潮气量预设的VCV模式相比,俯卧位PCV模式患者IOB较少,下Ppeak和CVP,脊柱手术中PaO2/FiO2较高。然而,在血流动力学变量(HR和MAP)方面,PCV和VCV之间没有明显差异。
UNASSIGNED: Many studies have investigated a comparison of the potency and safety of PCV versus VCV modes in spinal surgery in prone position. However, controversy about the maximal benefits of which ventilation modes remains. The main purpose of this meta-analysis was to investigate which one is the optimal ventilation for surgery patients undergoing spine surgery in prone position between the two ventilation modes as PCV and VCV.
UNASSIGNED: We conducted a comprehensive search of PubMed, Embase, Web of Science, the Cochrane Library, and Google Scholar for potentially eligible articles. The continuous outcomes were analyzed using the mean difference and the associated 95% confidence interval. Meta-analysis was performed using Review Manager 5.4 software.
UNASSIGNED: Our meta-analysis included 8 RCTs involving a total of 454 patients between 2012 and 2020. The results demonstrated that IOB, Ppeak and CVP for VCV are significantly superior to PCV in spinal surgery in prone position. And PCV had higher Cdyn and PaO2/FiO2 than VCV. But there was no significant difference between PCV and VCV in terms of POB, Hb, HCT, HR and MAP.
UNASSIGNED: The PCV mode displayed a more satisfying effect than VCV mode. Compared to VCV mode in same preset of tidal volume, the patients with PCV mode in prone position demonstrated less IOB, lower Ppeak and CVP, and higher PaO2/FiO2 in spinal surgery. However, there is no obvious difference between PCV and VCV in terms of hemodynamics variables (HR and MAP).