背景:原发性乳腺血管肉瘤是一种罕见的肿瘤,仅占所有乳腺恶性肿瘤的0.05%。原发性乳腺血管肉瘤通常表现为非特异性临床表现。这很容易导致误诊。导致误诊的潜在因素包括皮肤变化,这些变化可能被错误地归因于乳房外伤引起的瘀伤和乳房肿胀,可能被误认为是炎症性疾病或其他良性肿瘤。
方法:一名19岁女性因左乳外伤后9个月反复形成左乳肿块入院。
方法:经血肿活检确诊为原发性乳腺血管肉瘤。
方法:由于患者的病情,术后未给予特殊治疗。在那之后,胸壁复发了,患者接受了2个周期的化疗,导致复发性胸壁肿块的大小减少和减轻。当化疗不耐受发生时,患者选择停止治疗.
结果:经过18个月的随访,复发的胸壁肿块增加,患者死于出血。
结论:原发性乳腺血管肉瘤发病率低,恶性程度高,具有很高的复发率和转移率,导致预后不良。辅助化疗,放射治疗,靶向治疗,应考虑其他治疗方法,以降低局部复发率,延长患者生存期。
BACKGROUND: Primary breast angiosarcoma is a rare tumor, accounting for only 0.05% of all malignant breast tumors. The primary breast angiosarcoma typically presents with nonspecific clinical manifestations, which can easily lead to misdiagnosis. Potential factors contributing to misdiagnosis include skin changes that may be erroneously attributed to breast trauma-induced bruising and breast swelling that may be mistaken for inflammatory diseases or other benign tumors.
METHODS: A 19-year-old female was admitted to the hospital due to repeated lump formation in the left breast for 9 months after left breast trauma.
METHODS: The diagnosis of primary breast angiosarcoma was confirmed on hematoma biopsy.
METHODS: Due to the patient\'s condition, no special treatment was given postoperatively. After then, there was a recurrence in the chest wall, and the patient received 2 cycles of chemotherapy, resulting in a reduction in the size and lightening of the recurrent chest wall mass. When chemotherapy intolerance happened, the patient chose to discontinue treatment.
RESULTS: After an 18-month follow-up, the recurrent chest wall mass increased and the patient died from bleeding.
CONCLUSIONS: Primary breast angiosarcoma has a low incidence but high malignancy, with a high recurrence and metastasis rate, leading to a poor prognosis. The adjuvant chemotherapy, radiotherapy, targeted therapy, and other treatments should be considered to reduce the local recurrence rate and prolong patient survival.