UNASSIGNED: Light-sheet fluorescence microscopy (LSFM) has emerged as a powerful and versatile imaging technique renowned for its remarkable features, including high-speed 3D tomography, minimal photobleaching, and low phototoxicity. The interference light-sheet fluorescence microscope, with its larger field of view (FOV) and more uniform axial resolution, possesses significant potential for a wide range of applications in biology and medicine.
UNASSIGNED: The aim of this study is to investigate the interference behavior among multiple light sheets (LSs) in LSFM and optimize the FOV and resolution of the light-sheet fluorescence microscope.
UNASSIGNED: We conducted a detailed investigation of the interference effects among LSs through theoretical derivation and numerical simulations, aiming to find optimal parameters. Subsequently, we constructed a customized system of multi-LSFM that incorporates both interference light sheets (ILS) and noninterference light-sheet configurations. We performed beam imaging and microsphere imaging tests to evaluate the FOV and axial resolution of these systems.
UNASSIGNED: Using our custom-designed light-sheet fluorescence microscope, we captured the intensity distribution profiles of both interference and noninterference light sheets (NILS). Additionally, we conducted imaging tests on microspheres to assess their imaging outcomes. The ILS not only exhibits a larger FOV compared to the NILS but also demonstrates a more uniform axial resolution.
UNASSIGNED: By effectively modulating the interference among multiple LSs, it is possible to optimize the intensity distribution of the LSs, expand the FOV, and achieve a more uniform axial resolution.

Cone-beam computed tomography (CBCT) is a widely used imaging technique in interventional radiology. Although CBCT offers great advantages in terms of improving comprehension of complex angioarchitectures and guiding therapeutic decisions, its additional degree of radiation exposure has also aroused considerable concern. In this study, we aimed to assess radiation exposure and its influential factors in patients undergoing CBCT scans of the head and abdomen during interventional procedures. A total of 752 patients were included in this retrospective study. Dose area product (DAP) and reference air kerma (RAK) were used as measures of patient dose. The results showed that the median values of DAP were 53.8 (50.5-64.4) Gy⋅cm2 for head CBCT and 47.4 (39.6-54.3) Gy⋅cm2 for that of the abdomen. Male gender and body mass index (BMI) were characterized by increased DAP and RAK values in both head and abdominal CBCT scans. Larger FOV size was associated with a higher DAP but a lower RAK value, especially in head CBCT scans. Exposure parameters under automatic exposure control (AEC) also varied according to patient BMI and gender. In conclusion, the patients received slightly higher radiation doses from head CBCT scans than from those applied to the abdomen. BMI, gender, and FOV size were the key factors that influenced the radiation dose administered to the patients during CBCT scans. Our results may help to define and minimize patients\' exposure to radiation.

The field of view and single-star measurement accuracy are crucial metrics for assessing the performance of a star sensor. The field of view determines the spatial range of stars that can be captured by the sensor, while the single-star measurement accuracy determines the precision of attitude determination and control for the star sensor. The optical system of conventional star sensors is constrained by imaging relationships. Once the detector is determined, improving either the field of view or the single-star measurement accuracy will result in the degradation of the other. To address this issue, we propose an optical system for star sensors with accuracy performance varying with the field of view. By controlling the relationship between the field focal length of the optical system and the field of view, it is possible to simultaneously enhance both the field of view and the single-star measurement accuracy. We have designed corresponding optical systems to address the requirements for improving the single-star measurement accuracy and field of view. The design results confirm the feasibility of this star sensor. The star sensors are capable of simultaneously meeting the requirements for star pattern recognition and attitude determination, presenting broad application prospects in fields such as space navigation.

OBJECTIVE: To investigate the characteristics and objective assessment method of visual field defects caused by optic chiasm and its posterior visual pathway injury.
METHODS: Typical cases of visual field defects caused by injuries to the optic chiasm, optic tracts, optic radiations, and visual cortex were selected. Visual field examinations, visual evoked potential (VEP) and multifocal visual evolved potential (mfVEP) measurements, craniocerebral CT/MRI, and retinal optical coherence tomography (OCT) were performed, respectively, and the aforementioned visual electrophysiological and neuroimaging indicators were analyzed comprehensively.
RESULTS: The electrophysiological manifestations of visual field defects caused by optic chiasm injuries were bitemporal hemianopsia mfVEP abnormalities. The visual field defects caused by optic tract, optic radiation, and visual cortex injuries were all manifested homonymous hemianopsia mfVEP abnormalities contralateral to the lesion. Mild relative afferent pupil disorder (RAPD) and characteristic optic nerve atrophy were observed in hemianopsia patients with optic tract injuries, but not in patients with optic radiation or visual cortex injuries. Neuroimaging could provide morphological evidence of damages to the optic chiasm and its posterior visual pathway.
CONCLUSIONS: Visual field defects caused by optic chiasm, optic tract, optic radiation, and visual cortex injuries have their respective characteristics. The combined application of mfVEP and static visual field measurements, in combination with neuroimaging, can maximize the assessment of the location and degree of visual pathway damage, providing an effective scheme for the identification of such injuries.
目的: 探讨视交叉及其后部视路损伤所致视野缺损的特点及其客观评定方法。方法: 选择视交叉、视束、视放射及视皮质损伤所致视野缺损典型案例，分别进行视野、视觉诱发电位（visual evoked potential，VEP）、多焦视觉诱发电位（multifocal visual evoked potential，mfVEP）检查以及颅脑CT或MRI、视网膜光学相干断层扫描（optical coherence tomography，OCT），并对上述视觉电生理指标及神经影像学指标进行综合分析。结果: 视交叉损伤所致视野缺损的电生理学表现为双颞侧偏盲型mfVEP异常；视束、视放射及视皮质损伤所致视野缺损均表现为病变对侧的同向性偏盲型mfVEP异常。视束损伤出现偏盲眼轻度相对性传入性瞳孔障碍（relative afferent pupil disorder，RAPD）及特征性视神经萎缩表现，视放射、视皮质损伤则无此表现。神经影像学可为视交叉及其后部视路损伤提供形态学证据。结论: 视交叉、视束、视放射及视皮质损伤所致视野缺损具有各自特点，通过mfVEP视野与静态视野检查的联合应用，结合神经影像学检查，可最大程度地评价视路受损的部位和程度，为此类损伤的认定提供有效方案。.

Objective. High energy and large field of view (FOV) phase contrast imaging is crucial for biological and even medical applications. Although some works have devoted to achieving a large FOV at high energy through bending gratings and so on, which would be extremely challenging in medical high energy imaging.Approach.We analyze the angular shadowing effect of planar gratings in high-energy x-ray Talbot-Lau interferometer (XTLI). Then we design and develop an inverse XTLI coupled with a microarray anode-structured target source to extend the FOV at high energy.Main results.Our experimental results demonstrate the benefit of the source in the inverse XTLI and a large FOV of 106.6 mm in the horizontal direction is achieved at 40 keV. Based on this system, experiments of a mouse demonstrate the potential advantage of phase contrast mode in imaging lung tissue.Significance.We extend the FOV in a compact XTLI using a microarray anode-structured target source coupled with an inverse geometry, which eliminates grating G0 and relaxes the fabrication difficulty of G2. We believe the established design idea and imaging system would facilitate the wide applications of XTLI in high energy phase contrast imaging.

Risley-prism-based image sensors can expand the imaging field of view through beam control. The larger the top angle of the prism, the higher the magnification of the field of view, but at the same time, it aggravates the problem of imaging aberrations, which also puts higher requirements on the aberration correction method for the Risley-prism-based image sensor. To improve the speed, accuracy, and stability of the aberration correction process, an automatic calibration method for the Risley-prism-based image sensor is proposed based on a two-axis turntable. The image datasets of the calibration plate with different prism rotation angles and object distances are acquired using a two-axis turntable. Then, the images of the calibration plate are pre-processed using the bicubic interpolation algorithm. The calibration parameters are finally calculated, and parameter optimization is performed. The experimental results verify the feasibility of this automated calibration method. The reprojection error of the calibration is within 0.26 pixels when the distance of the imaging sensor is 3.6 m from the object, and the fine aberration correction results are observed.

The study aimed to introduce a novel imaging method that generates large-coverage, weight-bearing, and 3D images of the whole spine. The proposed system comprises an X-ray tube, a flat panel detector, and a standing platform. The standing platform rotates the imaged subject, allowing for the acquisition of serial fluoroscopic images from different angles which can be used to create 3D images. To increase the longitudinal coverage, we apply a segmental scanning pattern in which the imaged region is scanned in segments and stitched. To address the issue of data inaccuracy between the segments, redundant areas are set at margins of the segmental images, and registration and stitching algorithms are applied. We conducted validation experiments to evaluate radiation dose and image quality. The dose was evaluated using the volume CT dose index (CTDIvol). For image quality evaluation, we measured the low-contrast and spatial resolution. Additionally, we conducted a clinical study consisting of 30 volunteers with adolescent idiopathic scoliosis who were imaged by our method, and the images were subjectively assessed based on image noise, artifacts, anatomical coverage, diagnostic confidence, and overall quality. The CTDIvol was 1.23 mGy, and the low-contrast resolution was 0.6% at 4 mm and the spatial resolution was 8 lp/cm. The clinical images were generally of good quality, with high scores for all factors evaluated. Our method successfully generates large-coverage, weight-bearing, and 3D images of the whole spine with high image quality and low radiation dose. It shows potential for wider clinical applications for various musculoskeletal conditions.

BACKGROUND: This study aimed to evaluate the influence of field of view (FOV) and voxel size on the accuracy of dynamic navigation (DN)-assisted endodontic microsurgery (EMS).
METHODS: Nine sets of maxillary and mandibular 3-dimensional-printed jaw models composed of 180 teeth were divided into 9 groups with different FOVs (80 × 80 mm, 60 × 60 mm, and 40 × 40 mm) and voxel sizes (0.3 mm, 0.16 mm, and 0.08 mm). The endodontic DN system was used to plan and execute the EMS. The accuracy of the DN-EMS was represented by the platform deviation, end deviation, angular deviation, resection angle, and resection length deviation. Statistical analyses were performed using SPSS 24.0, and the significance level was set at P < .05.
RESULTS: The average platform deviation, end deviation, angular deviation, resection angle, and resection length deviation were 0.69 ± 0.31 mm, 0.93 ± 0.44 mm, 3.47 ± 1.80°, 2.35 ± 1.76°, and 0.41 ± 0.29 mm, respectively. No statistically significant differences in accuracy were observed between the nine FOV and voxel size groups.
CONCLUSIONS: FOV and voxel size did not appear to play an important role in the accuracy of DN-EMS. Considering the image quality and radiation dose, it is reasonable to select a limited FOV (such as 40 × 40 mm and 60 × 60 mm) to cover only the registration device, involved teeth, and periapical lesion. The voxel size should be selected according to the required resolution and cone-beam computed tomography units.

Continued research in fields such as materials science and biomedicine requires the development of a super-resolution imaging technique with a large field of view (FOV) and deep subwavelength resolution that is compatible with both fluorescent and nonfluorescent samples. Existing on-chip super-resolution methods exclusively focus on either fluorescent or nonfluorescent imaging, and, as such, there is an urgent requirement for a more general technique that is capable of both modes of imaging. In this study, to realize labeled and label-free super-resolution imaging on a single scalable photonic chip, a universal super-resolution imaging method based on the tunable virtual-wavevector spatial frequency shift (TVSFS) principle is introduced. Using this principle, imaging resolution can be improved more than threefold over the diffraction limit of a linear optical system. Here, diffractive units are fabricated on the chip\'s surface to provide wavevector-variable evanescent wave illumination, enabling tunable spatial frequency shifts in the Fourier space. A large FOV and resolutions of λ/4.7 and λ/7.1 were achieved for label-free and fluorescently labeled samples using a gallium phosphide (GaP) chip. With its large FOV, compatibility with different imaging modes, and monolithic integration, the proposed TVSFS chip may advance fields such as cell engineering, precision industry inspection, and chemical research.

This paper investigates a composite optical receiver for an indoor visible light communication (VLC) system. The optical gain, received power, and signal-to-noise ratio (SNR) are considered to be optimized. However, it is difficult to find a balance between them in general design and optimization. We propose the Taguchi and fuzzy logic combination method to improve multiple performance characteristics effectively in the optical receiver. The simulated results indicate that the designed receiver has the characteristics of an optical gain of 10.57, a half field of view (HFOV) of 45°, a received power of 6.4635 dBm, a signal-to-noise ratio (SNR) of 89.8874 dB, and a spot size of 2 mm. The appropriate weights of the three performance characteristics for the inputs of the fuzzy controllers increase the optical gain by 13.601 dB, and the received power and SNR by 11.097 dB and 0.373 dB, respectively. Therefore, the optical receiver optimally designed by the Taguchi and fuzzy logic methods can significantly meet the requirements of an indoor VLC system.