The improper storage of seeds can potentially compromise agricultural productivity, leading to reduced crop yields. Therefore, assessing seed viability before sowing is of paramount importance. Although numerous techniques exist for evaluating seed conditions, this research leveraged hyperspectral imaging (HSI) technology as an innovative, rapid, clean, and precise nondestructive testing method. The study aimed to determine the most effective classification model for watermelon seeds. Initially, purchased watermelon seeds were segregated into two groups: One underwent sterilization in a dehydrator machine at 40°C for 36 h, whereas the other batch was stored under favorable conditions. Watermelon seeds\' spectral images were captured using an HSI with a charge-coupled device camera ranging from 400 to 1000 nm, and the segmented regions of all samples were measured. Preprocessing techniques and wavelength selection methods were applied to manage spectral data workload, followed by the implementation of a support vector machine (SVM) model. The initial hybrid-SVM model achieved a predictive accuracy rate of 100%, with a test set accuracy of 92.33%. Subsequently, an artificial bee colony (ABC) optimization was introduced to enhance model precision. The results indicated that, with kernel parameters (c, g) set at 13.17 and 0.01, respectively, and a runtime of 4.19328 s, the training and evaluation of the dataset achieved an accuracy rate of 100%. Hence, it was practical to utilize HSI technology combined with the PCA-ABC-SVM model to detect different watermelon seeds. As a result, these findings introduce a novel technique for accurately forecasting seed viability, intended for use in agricultural industrial multispectral imaging. PRACTICAL APPLICATION: The traditional methods for determining the condition of seeds primarily emphasize aesthetics, rely on subjective assessment, are time-consuming, and require a lot of labor. On the other hand, HSI technology as green technology was employed to alleviate the aforementioned problems. This work significantly contributes to the field of industrial multispectral imaging by enhancing the capacity to discern various types of seeds and agricultural crop products.

UNASSIGNED: Brain-computer interfaces (BCIs) are systems that acquire the brain\'s electrical activity and provide control of external devices. Since electroencephalography (EEG) is the simplest non-invasive method to capture the brain\'s electrical activity, EEG-based BCIs are very popular designs. Aside from classifying the extremity movements, recent BCI studies have focused on the accurate coding of the finger movements on the same hand through their classification by employing machine learning techniques. State-of-the-art studies were interested in coding five finger movements by neglecting the brain\'s idle case (i.e., the state that brain is not performing any mental tasks). This may easily cause more false positives and degrade the classification performances dramatically, thus, the performance of BCIs. This study aims to propose a more realistic system to decode the movements of five fingers and the no mental task (NoMT) case from EEG signals.
UNASSIGNED: In this study, a novel praxis for feature extraction is utilized. Using Proper Rotational Components (PRCs) computed through Intrinsic Time Scale Decomposition (ITD), which has been successfully applied in different biomedical signals recently, features for classification are extracted. Subsequently, these features were applied to the inputs of well-known classifiers and their different implementations to discriminate between these six classes. The highest classifier performances obtained in both subject-independent and subject-dependent cases were reported. In addition, the ANOVA-based feature selection was examined to determine whether statistically significant features have an impact on the classifier performances or not.
UNASSIGNED: As a result, the Ensemble Learning classifier achieved the highest accuracy of 55.0% among the tested classifiers, and ANOVA-based feature selection increases the performance of classifiers on five-finger movement determination in EEG-based BCI systems.
UNASSIGNED: When compared with similar studies, proposed praxis achieved a modest yet significant improvement in classification performance although the number of classes was incremented by one (i.e., NoMT).

Accurate segmentation of liver tumors is a prerequisite for early diagnosis of liver cancer. Segmentation networks extract features continuously at the same scale, which cannot adapt to the variation of liver tumor volume in computed tomography (CT). Hence, a multi-scale feature attention network (MS-FANet) for liver tumor segmentation is proposed in this paper. The novel residual attention (RA) block and multi-scale atrous downsampling (MAD) are introduced in the encoder of MS-FANet to sufficiently learn variable tumor features and extract tumor features at different scales simultaneously. The dual-path feature (DF) filter and dense upsampling (DU) are introduced in the feature reduction process to reduce effective features for the accurate segmentation of liver tumors. On the public LiTS dataset and 3DIRCADb dataset, MS-FANet achieved 74.2% and 78.0% of average Dice, respectively, outperforming most state-of-the-art networks, this strongly proves the excellent liver tumor segmentation performance and the ability to learn features at different scales.

Aiming at accurate survival prediction of Glioblastoma (GBM) patients following radiation therapy, we developed a subregion-based survival prediction framework via a novel feature construction method on multi-sequence MRIs. The proposed method consists of two main steps: (1) a feature space optimization algorithm to determine the most appropriate matching relation derived between multi-sequence MRIs and tumor subregions, for using multimodal image data more reasonable; (2) a clustering-based feature bundling and construction algorithm to compress the high-dimensional extracted radiomic features and construct a smaller but effective set of features, for accurate prediction model construction. For each tumor subregion, a total of 680 radiomic features were extracted from one MRI sequence using Pyradiomics. Additional 71 geometric features and clinical information were collected resulting in an extreme high-dimensional feature space of 8231 to train and evaluate the survival prediction at 1 year, and the more challenging overall survival prediction. The framework was developed based on 98 GBM patients from the BraTS 2020 dataset under five-fold cross-validation, and tested on an external cohort of 19 GBM patients randomly selected from the same dataset. Finally, we identified the best matching relationship between each subregion and its corresponding MRI sequence, a subset of 235 features (out of 8231 features) were generated by the proposed feature bundling and construction framework. The subregion-based survival prediction framework achieved AUCs of 0.998 and 0.983 on the training and independent test cohort respectively for 1 year survival prediction, compared to AUCs of 0.940 and 0.923 for survival prediction using the 8231 initial extracted features for training and validation cohorts respectively. Finally, we further constructed an effective stacking structure ensemble regressor to predict the overall survival with the C-index of 0.872. The proposed subregion-based survival prediction framework allow us to better stratified patients towards personalized treatment of GBM.

DNA synthesis is widely used in synthetic biology to construct and assemble sequences ranging from short RBS to ultra-long synthetic genomes. Many sequence features, such as the GC content and repeat sequences, are known to affect the synthesis difficulty and subsequently the synthesis cost. In addition, there are latent sequence features, especially local characteristics of the sequence, which might affect the DNA synthesis process as well. Reliable prediction of the synthesis difficulty for a given sequence is important for reducing the cost, but this remains a challenge. In this study, we propose a new automated machine learning (AutoML) approach to predict the DNA synthesis difficulty, which achieves an F1 score of 0.930 and outperforms the current state-of-the-art model. We found local sequence features that were neglected in previous methods, which might also affect the difficulty of DNA synthesis. Moreover, experimental validation based on ten genes of Escherichia coli strain MG1655 shows that our model can achieve an 80% accuracy, which is also better than the state of art. Moreover, we developed the cloud platform SCP4SSD using an entirely cloud-based serverless architecture for the convenience of the end users.

OBJECTIVE: Knee-joint vibroarthrographic (VAG) signal is an effective method for performing a non-invasive knee osteoarthritis (KOA) diagnosis, VAG signal analysis plays a crucial role in achieving the early pathological screening of the knee joint. In order to improve the accuracy of knee pathology screening and to investigate the method suitable for embedded in wearable diagnostic device for knee joint, this paper proposes a knee pathology screening method. Aiming to fill the gap of lacking suitable and unified evaluation indexes for single feature and fusion feature, this paper proposes feature separability evaluation criteria.
METHODS: In this paper, we propose a knee joint pathology screening method based on feature fusion and dimension reduction combined with random forest classifier, as well as, the evaluation criteria of feature separability. As for pathological screening method, this paper proposes the idea of multi-dimensional feature fusion, using principal component analysis (PCA) to reduce the redundant part of fusion feature (F-F) to obtain deep fusion feature (D-F-F) with more separability. Meanwhile, this paper proposes the maximal information coefficient (MIC) and correlation matrix collinearity (CMC) feature evaluation criteria, these not only can be used as new feature quantitative metrics, but also illustrate that the divisibility of the deep fusion feature is more potent than that before feature dimension reduction.
RESULTS: The experimental results show that the method in this paper has good performance in pathology classification on random forest classifier with 96% accuracy, especially the accuracy of SVM and K-NN are also improved after feature dimension reduction.
CONCLUSIONS: The results indicate that this classification research has high screening efficiency for KOA diagnosis and could provide a feasible method for computer-assisted non-invasive diagnosis of KOA. And we provide a novel way for separability evaluation of VAG signal features.

This study aimed to utilize machine learning algorithems combined with feature reduction for predicting pyrolytic gas yield and compositions based on pyrolysis conditions and biomass characteristics. To this end, random forest (RF) and support vector machine (SVM) was introduced and compared. The results suggested that six features were adequate to accurately forecast (R2 > 0.85, RMSE < 5.7%) the yield while the compositions only required three. Moreover, the profound information behind the models was extracted. The relative contribution of pyrolysis conditions was higher than that of biomass characteristics for yield (55%), CO2 (73%), and H2 (81%), which was inverse for CO (12%) and CH4 (38%). Furthermore, partial dependence analysis quantified the effects of both reduced features and their interactions exerted on pyrolysis process. This study provided references for pyrolytic gas production and upgrading in a more convenient manner with fewer features and extended the knowledge into the biomass pyrolysis process.

In the clinical diagnosis of epileptic diseases, the intelligent diagnosis of epileptic electroencephalogram (EEG) signals has become a research focus in the field of brain diseases. In order to solve the problem of time-consuming and easily influenced by human subjective factors, artificial intelligence pattern recognition algorithm has been applied to EEG signals recognition. However, at present, the common empirical mode decomposition (EMD) signal decomposition algorithm does not consider the problem of mode aliasing. The EEG features obtained by feature extraction may be mixed with some unimportant features that affect the classification accuracy. In this paper, we proposed a new method based on complementary ensemble empirical mode decomposition (CEEMD) combined with iterative feature reduction for aided diagnosis of epileptic EEG. First of all, the evaluation indexes of decomposing and reconstructing signals by several methods were compared. The CEEMD was selected as the decomposition method of the signals. Then, the support vector machine recursive elimination (SVM-RFE) was used to reduce 9 features extracted from EEG data. The support vector classification of the gray wolf optimizer (GWO-SVC) recognition model was established for different feature subsets. By comparing the classification accuracy of training set and test set of different feature subsets, and considering the complexity of the model reflected by the number of features selected by SVM-RFE, the analysis showed that the 6 feature subsets with fewer features and higher classification accuracy could reflect the key information of epileptic EEG. The accuracy of the training set classification was 99.38% and the test set was as high as 100%. The recognition time was only 1.6551 s. Finally, in order to verify the reliability of the algorithm proposed in this paper, the proposed algorithm compared with the classification model established by the raw EEG signals and the optimization model established by other intelligent optimization algorithms. It is found that the algorithm used in this paper has higher classification accuracy and faster recognition time than other processing methods. The experimental results show that CEEMD combined with SVM-RFE is feasible for rapid and accurate recognition of EEG signals, which provides a theoretical basis for the aided diagnosis of epilepsy.

At present, the traditional scoring methods generally utilize laboratory measurements to predict mortality. It results in difficulties of early mortality prediction in the rural areas lack of professional laboratorians and medical laboratory equipment. To improve the efficiency, accuracy, and applicability of mortality prediction in the remote areas, a novel mortality prediction method based on machine learning algorithms is proposed, which only uses non-invasive parameters readily available from ordinary monitors and manual measurement. A new feature selection method based on the Bayes error rate is developed to select valuable features. Based on non-invasive parameters, four machine learning models were trained for early mortality prediction. The subjects contained in this study suffered from general critical diseases including but not limited to cancer, bone fracture, and diarrhea. Comparison tests among five traditional scoring methods and these four machine learning models with and without laboratory measurement variables are performed. Only using the non-invasive parameters, the LightGBM algorithms have an excellent performance with the largest accuracy of 0.797 and AUC of 0.879. There is no apparent difference between the mortality prediction performance with and without laboratory measurement variables for the four machine learning methods. After reducing the number of feature variables to no more than 50, the machine learning models still outperform the traditional scoring systems, with AUC higher than 0.83. The machine learning approaches only using non-invasive parameters achieved an excellent mortality prediction performance and can equal those using extra laboratory measurements, which can be applied in rural areas and remote battlefield for mortality risk evaluation. Graphical abstract.

[This corrects the article on p. 146 in vol. 9, PMID: 28572766.].