■调查数字健康干预措施对提高孕妇口服铁补充剂依从性的影响。
■从成立到2023年10月,搜索了五个数据库,没有日期限制。
■评估数字健康干预措施对口服补铁依从性影响的随机对照试验(RCT)(例如,片剂和胶囊)与针对孕妇的非数字健康干预措施相比是合格的。
■我们使用逆方差法对连续变量计算了具有95%置信区间(CI)的标准化平均差(SMD)和平均差(MD)。我们使用Mantel-Haenszel模型用95CI计算分类变量的比值比(OR)。使用建议分级评估来评估证据的确定性,发展,和评估(等级)方法。使用Cochrane偏倚风险工具2.0评估纳入的随机对照试验的偏倚风险。
■纳入10项试验,1,633名参与者。根据7项试验,与非数字健康干预相比,数字健康干预可以提高客观依从性(1,289名参与者,OR=4.07[2.19,7.57],p<0.001,I2=69%)在孕妇中。与非数字健康干预相比,数字健康干预可以改善主观依从性行为(3项试验,434名参与者,SMD=0.82[0.62,1.01],p<0.001,I2=0%)在孕妇中。基于3次试验,与非数字健康干预相比,数字健康干预可以改善平板电脑的消费(333名参与者,SMD=1.00[0.57,1.42],p<0.001,I2=66%)在孕妇中。与非数字健康干预相比,数字健康干预可以提高血红蛋白水平(7项试验,1,216名与会者,MD=0.59[0.31,0.88],p<0.001,I2=93%)在孕妇中。
■数字健康干预措施可有效改善孕妇对口服铁补充剂的依从性和血红蛋白水平。
UNASSIGNED: To investigate the effects of digital health interventions for improving adherence to oral iron supplementation in pregnant women.
UNASSIGNED: Five databases were searched from their inception to October 2023 with no date restrictions.
UNASSIGNED: Randomized controlled trials (RCTs) that assessed the effects of digital health interventions on adherence to oral iron supplementation (e.g., tablets and capsules) compared to non-digital health interventions for pregnant women were eligible.
UNASSIGNED: We calculated standardized mean differences (SMDs) and mean differences (MDs) with 95% confidence intervals (CIs) for continuous variables using the inverse variance method. We calculated odds ratios (OR) with 95%CI for categorical variables using the Mantel-Haenszel model. The certainty of the evidence was assessed using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach. The risk of bias of the included RCTs was assessed using the Cochrane risk of bias tool 2.0.
UNASSIGNED: Ten trials with 1,633 participants were included. Based on 7 trials, digital health interventions can improve objective adherence rate comparing with non-digital health interventions (1,289 participants, OR = 4.07 [2.19, 7.57], p < 0.001, I2 = 69%) in pregnant women. Digital health interventions can improve subjective adherence behavior comparing with non-digital health interventions (3 trials, 434 participants, SMD = 0.82 [0.62, 1.01], p < 0.001, I2 = 0%) in pregnant women. Based on 3 trials, digital health interventions can improve tablets consumption comparing with non-digital health interventions (333 participants, SMD = 1.00 [0.57, 1.42], p < 0.001, I2 = 66%) in pregnant women. Digital health interventions can improve hemoglobin level comparing with non-digital health interventions (7 trials, 1,216 participants, MD = 0.59 [0.31, 0.88], p < 0.001, I2 = 93%) in pregnant women.
UNASSIGNED: Digital health interventions were effective at improving adherence to oral iron supplementation and hemoglobin levels in pregnant women.