迄今为止,已经进行了一些研究来测试Carnoy's(CS)与改良Carnoy's(MC)溶液预防牙源性角化囊肿复发的有效性,这是潜在的侵袭性病变。为了评估MC应用的疗效，我们进行了为期18年的回顾性队列研究，从2004年10月到2022年10月，在122例接受辅助化学烧灼手术治疗的患者中，CS（n=73；中位年龄：30岁）或MC（n=49；中位年龄：42岁），一个外科医生。主要结果变量为观察复发和复发间隔。独立变量是人口统计学，location,基线时的临床表现，相邻拔牙，和植骨。男性在两组中占主导地位。在特定月份的复发方面，两组之间没有观察到统计学上的显着差异，CS组6例（8.2%），MC组5例（10.2%）。在11次复发中，在手术后的前2年内观察到10例，只有一个发生在随访的第7年。因此，当用作辅助治疗时，在降低牙源性角化囊肿的复发率方面，MC的应用与CS相当。
To date, few studies have been conducted to test the effectiveness of Carnoy\'s (CS) versus modified Carnoy\'s (MC) solution for preventing the recurrence of odontogenic keratocysts, which are potentially aggressive lesions. To evaluate the efficacy of MC application, we conducted a retrospective cohort study over an 18-year period, from October 2004 to October 2022, in 122 patients treated surgically with adjunctive chemical cautery, with either CS (n = 73; median age: 30 years) or MC (n = 49; median age: 42 years), by a single surgeon. The primary outcome variables were observed recurrence and interval to recurrence. Independent variables were demographics, location, clinical presentation at baseline, adjacent tooth extraction, and bone grafting. Males predominated in both groups. No statistically significant differences were observed between the two arms in terms of recurrences in particular months, with six patients (8.2%) in the CS arm and 5 (10.2%) in the MC arm. Of the 11 recurrences, 10 were observed within the first 2 years post-surgery, with only one occurring in the 7th year of follow-up. Thus, when used as adjunctive therapy, the application of MC has an efficiency comparable to that of CS for lowering the recurrence rate of odontogenic keratocysts.
